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BARNASE

  • Barnase
  • Bacterial ribonuclease protein

    Barnase (a portmanteau of "BActerial" "RiboNucleASE") is a bacterial protein that consists of 110 amino acids and has ribonuclease activity. It is synthesized

    Barnase

    Barnase

    Barnase

  • Barstar
  • Protein family

    activity of its binding partner barnase, with which it forms an extraordinarily tightly bound complex within the cell until barnase is secreted. Expression of

    Barstar

    Barstar

    Barstar

  • Phi value analysis
  • domains, WW domain, individual domains of proteins L and G, ubiquitin, and barnase have all been studied by φ {\displaystyle \varphi } analysis. Phi is defined

    Phi value analysis

    Phi_value_analysis

  • DMH-11 Mustard
  • Genetically modified variety of mustard plant

    transgenic technology, primarily involving the Bar, Barnase and Barstar gene system. The Barnase gene confers male sterility, while the Barstar gene restores

    DMH-11 Mustard

    DMH-11 Mustard

    DMH-11_Mustard

  • Mae-Wan Ho
  • Hong Kong geneticist

    bacterial gene barnase from transgenic plants. This gene kills any cell that expresses it and lacks barstar, the specific inhibitor of barnase activity. In

    Mae-Wan Ho

    Mae-Wan Ho

    Mae-Wan_Ho

  • Protein complex
  • Type of stable macromolecular complex

    The Bacillus amyloliquefaciens ribonuclease barnase (colored) and its inhibitor (blue) in a complex

    Protein complex

    Protein_complex

  • Bacillus amyloliquefaciens
  • Species of bacterium

    restriction enzyme.[citation needed] The species also synthesizes the enzyme barnase, a widely studied ribonuclease that forms a famously tight complex with

    Bacillus amyloliquefaciens

    Bacillus amyloliquefaciens

    Bacillus_amyloliquefaciens

  • Andreas Matouschek
  • American biologist

    resulted in the seminal application of phi-value analysis to the study of barnase, a bacterial RNAse used in many protein folding studies. Development of

    Andreas Matouschek

    Andreas_Matouschek

  • Jane Clarke (scientist)
  • English biochemist and academic

    Philosophy degree in 1993 for investigations of Bacterial Ribonuclease (Barnase) from the University of Cambridge supervised by Alan Fersht. Clarke was

    Jane Clarke (scientist)

    Jane Clarke (scientist)

    Jane_Clarke_(scientist)

  • Ribonuclease T1
  • Class of enzymes

    denatured RNA prior to sequencing. Similar to other ribonucleases such as barnase and RNase A, ribonuclease T1 has been popular for folding studies. Structurally

    Ribonuclease T1

    Ribonuclease T1

    Ribonuclease_T1

  • Bacillus
  • Genus of bacteria

    Bacillus amyloliquefaciens is the source of a natural antibiotic protein barnase (a ribonuclease), alpha amylase used in starch hydrolysis, the protease

    Bacillus

    Bacillus

    Bacillus

  • Alan Fersht
  • British chemist (born 1943)

    Fersht LMB Profile Clarke, Jane (1993). Studies of disulphide mutants of barnase. jisc.ac.uk (PhD thesis). University of Cambridge. OCLC 53666398. EThOS uk

    Alan Fersht

    Alan Fersht

    Alan_Fersht

  • Enzyme inhibitor
  • Molecule that blocks enzyme activity

    inhibitor proteins include the barstar inhibitor of the bacterial ribonuclease barnase. Animals and plants have evolved to synthesise a vast array of poisonous

    Enzyme inhibitor

    Enzyme inhibitor

    Enzyme_inhibitor

  • Cloning vector
  • Small piece of maintainable DNA

    This may involve the use of a gene lethal to the host cells, such as barnase, Ccda, and the parD/parE toxins. This typically works by disrupting or

    Cloning vector

    Cloning vector

    Cloning_vector

  • Expanded genetic code
  • Modified genetic code

    non-natural one. To remove the former, the plasmid is inserted into cells with a barnase gene (toxic) with a premature amber codon but without the non-natural amino

    Expanded genetic code

    Expanded genetic code

    Expanded_genetic_code

  • Cytoplasmic male sterility
  • Type of male sterility in hermaphrodite organisms

    of such (patented) systems, which require genetic manipulation, are: a Barnase gene construct, Pioneer's Seed Production Technology (SPT), Monsanto's

    Cytoplasmic male sterility

    Cytoplasmic_male_sterility

  • Omega loop
  • S2CID 2130725. Vu, ND; Feng, H; Bai, Y (30 Mar 2004). "The folding pathway of barnase: the rate-limiting transition state and a hidden intermediate under native

    Omega loop

    Omega_loop

  • List of biophysically important macromolecular crystal structures
  • transcriptase 1993 – Beta helix of Pectate lyase 1994 – Collagen 1994 – Barnase/barstar complex 1994 – F1 ATPase 1995 – Heterotrimeric G proteins 1996 –

    List of biophysically important macromolecular crystal structures

    List of biophysically important macromolecular crystal structures

    List_of_biophysically_important_macromolecular_crystal_structures

  • Shoshana Wodak
  • Computational biologist

    confirmation and the ribonucleotidecleavage reaction: implications for barnase catalysis", Proteins. February 1, 1097-0134. Sirota FL, Héry-Huynh S, Maurer-Stroh

    Shoshana Wodak

    Shoshana Wodak

    Shoshana_Wodak

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Online names & meanings

  • ACKLEA
  • Male

    English

    ACKLEA

    Variant spelling of English Ackley, ACKLEA means "oak meadow."

  • Vidhyuthsagar
  • Boy/Male

    Hindu

    Vidhyuthsagar

  • Anahata
  • Girl/Female

    Indian

    Anahata

  • Ellene
  • Girl/Female

    American, British, English, French, German, Greek

    Ellene

    Light; Most Beautiful Woman; Variant of Helen; Shining; Brightness

  • Bass
  • Surname or Lastname

    English

    Bass

    English : from Old French bas(se) ‘low’, ‘short’ (Latin bassus ‘thickset’; see Basso), either a descriptive nickname for a short person or a status name meaning ‘of humble origin’, not necessarily with derogatory connotations.English : in some instances, from Middle English bace ‘bass’ (the fish), hence a nickname for a person supposedly resembling this fish, or a metonymic occupational name for a fish seller or fisherman.Scottish : habitational name from a place in Aberdeenshire, of uncertain origin.Jewish (Ashkenazic) : metonymic occupational name for a maker or player of bass viols, from Polish, Ukrainian, and Yiddish bas ‘bass viol’.German : see Basse.

  • Hildie
  • Girl/Female

    English

    Hildie

    Battle maid.

  • Meetul | மிதுல
  • Boy/Male

    Tamil

    Meetul | மிதுல

    True friend, Limited

  • Ajatha
  • Girl/Female

    Indian

    Ajatha

    Having no enemy

  • Zoysa
  • Girl/Female

    Buddhist, Indian

    Zoysa

    Unique

  • Lindsey
  • Surname or Lastname

    Variant spelling of Scottish Lindsay.Irish

    Lindsey

    Variant spelling of Scottish Lindsay.Irish : reduced and Anglicized form of various Gaelic surnames, as for example Ó Loingsigh (see Lynch 1), Mac Giolla Fhionntóg (see McClintock), and Ó Fhloinn (see Flynn).English : habitational name from Lindsey in Suffolk, named in Old English as ‘island (Old English ēg) of Lelli’, a personal name representing a byform of an unattested name Lealla.

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