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Bacterial ribonuclease protein
Barnase (a portmanteau of "BActerial" "RiboNucleASE") is a bacterial protein that consists of 110 amino acids and has ribonuclease activity. It is synthesized
Barnase
Protein family
activity of its binding partner barnase, with which it forms an extraordinarily tightly bound complex within the cell until barnase is secreted. Expression of
Barstar
domains, WW domain, individual domains of proteins L and G, ubiquitin, and barnase have all been studied by φ {\displaystyle \varphi } analysis. Phi is defined
Phi_value_analysis
Genetically modified variety of mustard plant
transgenic technology, primarily involving the Bar, Barnase and Barstar gene system. The Barnase gene confers male sterility, while the Barstar gene restores
DMH-11_Mustard
Hong Kong geneticist
bacterial gene barnase from transgenic plants. This gene kills any cell that expresses it and lacks barstar, the specific inhibitor of barnase activity. In
Mae-Wan_Ho
Type of stable macromolecular complex
The Bacillus amyloliquefaciens ribonuclease barnase (colored) and its inhibitor (blue) in a complex
Protein_complex
Species of bacterium
restriction enzyme.[citation needed] The species also synthesizes the enzyme barnase, a widely studied ribonuclease that forms a famously tight complex with
Bacillus_amyloliquefaciens
American biologist
resulted in the seminal application of phi-value analysis to the study of barnase, a bacterial RNAse used in many protein folding studies. Development of
Andreas_Matouschek
English biochemist and academic
Philosophy degree in 1993 for investigations of Bacterial Ribonuclease (Barnase) from the University of Cambridge supervised by Alan Fersht. Clarke was
Jane_Clarke_(scientist)
Class of enzymes
denatured RNA prior to sequencing. Similar to other ribonucleases such as barnase and RNase A, ribonuclease T1 has been popular for folding studies. Structurally
Ribonuclease_T1
Genus of bacteria
Bacillus amyloliquefaciens is the source of a natural antibiotic protein barnase (a ribonuclease), alpha amylase used in starch hydrolysis, the protease
Bacillus
British chemist (born 1943)
Fersht LMB Profile Clarke, Jane (1993). Studies of disulphide mutants of barnase. jisc.ac.uk (PhD thesis). University of Cambridge. OCLC 53666398. EThOS uk
Alan_Fersht
Molecule that blocks enzyme activity
inhibitor proteins include the barstar inhibitor of the bacterial ribonuclease barnase. Animals and plants have evolved to synthesise a vast array of poisonous
Enzyme_inhibitor
Small piece of maintainable DNA
This may involve the use of a gene lethal to the host cells, such as barnase, Ccda, and the parD/parE toxins. This typically works by disrupting or
Cloning_vector
Modified genetic code
non-natural one. To remove the former, the plasmid is inserted into cells with a barnase gene (toxic) with a premature amber codon but without the non-natural amino
Expanded_genetic_code
Type of male sterility in hermaphrodite organisms
of such (patented) systems, which require genetic manipulation, are: a Barnase gene construct, Pioneer's Seed Production Technology (SPT), Monsanto's
Cytoplasmic_male_sterility
S2CID 2130725. Vu, ND; Feng, H; Bai, Y (30 Mar 2004). "The folding pathway of barnase: the rate-limiting transition state and a hidden intermediate under native
Omega_loop
transcriptase 1993 – Beta helix of Pectate lyase 1994 – Collagen 1994 – Barnase/barstar complex 1994 – F1 ATPase 1995 – Heterotrimeric G proteins 1996 –
List of biophysically important macromolecular crystal structures
List_of_biophysically_important_macromolecular_crystal_structures
Computational biologist
confirmation and the ribonucleotidecleavage reaction: implications for barnase catalysis", Proteins. February 1, 1097-0134. Sirota FL, Héry-Huynh S, Maurer-Stroh
Shoshana_Wodak
BARNASE
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Male
English
Variant spelling of English Ackley, ACKLEA means "oak meadow."
Boy/Male
Hindu
Girl/Female
Indian
Girl/Female
American, British, English, French, German, Greek
Light; Most Beautiful Woman; Variant of Helen; Shining; Brightness
Surname or Lastname
English
English : from Old French bas(se) ‘low’, ‘short’ (Latin bassus ‘thickset’; see Basso), either a descriptive nickname for a short person or a status name meaning ‘of humble origin’, not necessarily with derogatory connotations.English : in some instances, from Middle English bace ‘bass’ (the fish), hence a nickname for a person supposedly resembling this fish, or a metonymic occupational name for a fish seller or fisherman.Scottish : habitational name from a place in Aberdeenshire, of uncertain origin.Jewish (Ashkenazic) : metonymic occupational name for a maker or player of bass viols, from Polish, Ukrainian, and Yiddish bas ‘bass viol’.German : see Basse.
Girl/Female
English
Battle maid.
Boy/Male
Tamil
True friend, Limited
Girl/Female
Indian
Having no enemy
Girl/Female
Buddhist, Indian
Unique
Surname or Lastname
Variant spelling of Scottish Lindsay.Irish
Variant spelling of Scottish Lindsay.Irish : reduced and Anglicized form of various Gaelic surnames, as for example Ó Loingsigh (see Lynch 1), Mac Giolla Fhionntóg (see McClintock), and Ó Fhloinn (see Flynn).English : habitational name from Lindsey in Suffolk, named in Old English as ‘island (Old English ēg) of Lelli’, a personal name representing a byform of an unattested name Lealla.
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