Reference for BECN1. Search for BECN1

AI searches containing BECN1

BECN1

BECN1

Protein-coding gene in the species Homo sapiens

Beclin-1 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 is a mammalian ortholog of the yeast autophagy-related gene 6 (Atg6) and

BECN1

Psoriasis

Autoimmune diseases of the skin

and type 2 diabetes share four loci, namely, ACTR2, ERLIN1, TRMT112, and BECN1, which are connected via the inflammatory NF-κB pathway. While no cure is

Psoriasis

Ovarian cancer

Cancer originating in or on the ovary

amplification/mutation 6%, 20% ARID1A point mutation endometrioid and clear-cell BECN1 deletion BRAF point mutation low-grade serous 0.5% BRCA1 nonsense mutation

Ovarian cancer

Ovarian_cancer

Herpes simplex virus

Species of virus

Neurovirulence factor. Antagonizes PKR by de-phosphorylating eIF4a. Binds to BECN1 and inactivates autophagy. LAT LRP1, LRP2 P17588 P17589 Latency-associated

Herpes simplex virus

Herpes_simplex_virus

Beth Levine (physician)

American microbiologist (1960–2020)

University Medical College Known for Identified the mammalian autophagy gene BECN1/beclin 1 Spouse Milton Packer Children 2 Awards The American Cancer Society

Beth Levine (physician)

Beth_Levine_(physician)

Bcl-2

Protein found in humans

Bcl-2 has been shown to interact with: BAK1, BCAP31, BCL2-like 1, BCL2L11, BECN1, BID, BMF, BNIP2, BNIP3, BNIPL, BAD BAX, BIK, C-Raf, CAPN2, CASP8, Cdk1

Bcl-2

Zhenyu Yue

Chinese medical researcher

maintaining neuronal health. Yue reported the first mammalian autophagy gene (BECN1) function in vivo. Yue's laboratory identified key regulators of autophagy

Zhenyu Yue

Zhenyu_Yue

Rubicon (protein)

Human protein involved in autophagy regulation

Yamamoto-Imoto H, et al. (January 2019). "Bidirectional Control of Autophagy by BECN1 BARA Domain Dynamics". Molecular Cell. 73 (2): 339–353.e6. doi:10.1016/j

Rubicon (protein)

Rubicon_(protein)

List of human protein-coding genes 1

P23560 1506 BDP1 HGNC:13652; A6H8Y1 1507 BEAN1 HGNC:24160; Q3B7T3 1508 BECN1 HGNC:1034; Q14457 1509 BECN2 HGNC:38606; A8MW95 1510 BEGAIN HGNC:24163;

List of human protein-coding genes 1

List_of_human_protein-coding_genes_1

Housekeeping gene

Gene which maintains basic cellular functions

astrocyte-derived neurotrophic factor AES amino terminal enhancer of split BECN1 involved in autophagy and partners with PI3K BUD31 formerly Maternal G10

Housekeeping gene

Housekeeping_gene

ABHD5

Protein-coding gene in the species Homo sapiens

Shi C, Ye L, Sun W, Wang L, Liang H, Ou J (2016). "ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2"

ABHD5

GOPC

Protein-coding gene in humans

sequence-specific manner.[supplied by OMIM] GOPC has been shown to interact with GRID2, BECN1, RHOQ, ACCN3, Cystic fibrosis transmembrane conductance regulator and CSPG5

GOPC