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Medication used to treat anxiety disorders
Buspirone, sold under the name Buspar among others, is an anxiolytic medication primarily used for the treatment of generalized anxiety disorder. Unlike
Buspirone
Class of medications used to alleviate anxiety
anxiety disorders due to their fast onset but carry the risk of dependence. Buspirone is indicated for GAD, which has much slower onset but with the advantage
Anxiolytic
Combination drug
Buspirone/testosterone (tentative brand name Lybridos) is a combination of buspirone, a 5-HT1A receptor partial agonist, α2-adrenergic receptor antagonist
Buspirone/testosterone
Pharmaceutical compound
Buspirone/zolmitriptan, also known by its developmental code names AV-2860 and JM-010, is a combination of buspirone, a serotonin 5-HT1A receptor partial
Buspirone/zolmitriptan
Class of psychotropic drugs
(S-20,499) Binospirone (MDL-73,005) BMY-7,378 (CAS number: 21102-95-4 ) Buspirone (Buspar) Enilospirone (CERM-3,726) Eptapirone (F-11,440) Gepirone (Exxua)
Azapirone
Chemical compound
A number of pyrimidinylpiperazine derivatives are drugs, including: Buspirone – anxiolytic Dasatinib – anticancer agent Eptapirone – anxiolytic Gepirone –
Pyrimidinylpiperazine
Pharmaceutical compound
models of anxiety, whereas buspirone was ineffective in the same models. In contrast to diazepam but similarly to buspirone, FR260010 has modest adverse
FR260010
Motor symptoms caused by dysfunction of the cerebellum
to moderate cerebellar ataxia may be treatable with buspirone. It is thought that the buspirone increases the serotonin levels in the cerebellum and
Cerebellar_ataxia
Chemical which binds to and activates a biochemical receptor
specific type of receptor. E.g. buspirone is a selective agonist for serotonin 5-HT1A. Partial agonists (such as buspirone, aripiprazole, buprenorphine,
Agonist
Medication used for major depressive disorder
the D2 receptor (30- to 50-fold lower in comparison to buspirone). However, similarly to buspirone, gepirone metabolizes into 1-(2-pyrimidinyl)piperazine
Gepirone
Pharmaceutical compound
activity than other serotonin 5-HT1A receptor agonists, such as 8-OH-DPAT, buspirone, gepirone, F-15599 (NLX-101), and vilazodone, among others. On the other
TMU4142
Drug interactions with grapefruit juice
norbuprenorphine by CYP3A4 Buspirone (Buspar): Grapefruit juice increased peak and AUC plasma concentrations of buspirone 4.3- and 9.2-fold, respectively
Grapefruit–drug_interactions
Drug that blocks hallucinogen effects
psychedelics. Examples include serotonin 5-HT1A receptor agonists like buspirone, serotonin reuptake inhibitors such as selective serotonin reuptake inhibitors
Trip_killer
Anxiolytic and antidepressant medication
azapirone class of drugs and is closely related to other azapirones like buspirone and gepirone. Tandospirone was introduced for medical use in Japan in
Tandospirone
Chemical compound
effectiveness seen with already available 5-HT1A receptor agonists like buspirone and tandospirone, which act merely as weak-to-moderate partial agonists
Eptapirone
Class of antidepressant medication
bupropion; and for overall sexual dysfunction, switching to nefazodone. Buspirone is sometimes used off-label to reduce sexual dysfunction associated with
Selective serotonin reuptake inhibitor
Selective_serotonin_reuptake_inhibitor
Agonist drug having partial efficacy at a receptor
have been classed as partial agonists at particular receptors include buspirone, aripiprazole, buprenorphine, clobazam, nordazepam, nalmefene and norclozapine
Partial_agonist
Protein family
weak antagonist at the α2A and α2B subtypes. 1-PP (active metabolite of buspirone and gepirone) Aripiprazole Asenapine Atipamezole Cirazoline Clozapine
Alpha-2_adrenergic_receptor
antidepressants, antipsychotics, ergolines, and some piperazines like buspirone, trazodone, nefazodone, etoperidone, and mepiprazole antagonize α1-adrenergic
List_of_adrenergic_drugs
Moderate-size cluster of nuclei found in brain stem
the brain and decrease the release of serotonin. The anxiolytic drug Buspirone acts as partial agonist against these receptors. Selective serotonin reuptake
Raphe_nuclei
include: None currently approved Modafinil (Provigil) Armodafinil (Nuvigil) Buspirone (Buspar) – 5-HT1A receptor partial agonist Lithium (Eskalith, Lithobid)
List_of_antidepressants
Serotonin receptor protein distributed in the cerebrum and raphe nucleus
5-HT1A receptor agonists like buspirone and flesinoxan show efficacy in relieving anxiety and depression. Buspirone, tandospirone, and gepirone are
5-HT1A_receptor
Class of antidepressant medication
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Atypical_antidepressant
Medication
Mayer N, et al. (June 2002). "Region-dependent effects of flibanserin and buspirone on adenylyl cyclase activity in the human brain". The International Journal
Flibanserin
Symptoms caused by an excess of serotonin in the central nervous system
(TCAs), amphetamines, pethidine (meperidine), tramadol, dextromethorphan, buspirone, L-tryptophan, 5-hydroxytryptophan, St. John's wort, triptans, MDMA, metoclopramide
Serotonin_syndrome
Investigational anxiety disorder drugs
– corticotropin-releasing hormone (CRH) inhibitor [24] Buspirone controlled release (Buspirone ER) – serotonin 5-HT1A receptor partial agonist and other
List of investigational anxiety disorder drugs
List_of_investigational_anxiety_disorder_drugs
Anxiety disorder associated with social situations
effects of buspirone in social phobia: a double-blind placebo-controlled study National Library of Medicine. 1993. Retrieved 14 August 2025. Buspirone in social
Social_anxiety_disorder
List of pharmaceutical drugs under clinical development for treatment of depression
serotonin reuptake inhibitor and serotonin 5-HT1A and 5-HT1D receptor agonist Buspirone (transdermal; BuSpar Patch) – serotonin 5-HT1A receptor partial agonist
List of investigational antidepressants
List_of_investigational_antidepressants
Antihistamine drug
Insufficient data were available to compare the drug with benzodiazepines and buspirone. Hydroxyzine can also be used for the treatment of allergic conditions
Hydroxyzine
Brazil's federal drug control statute
Benzoctamine Benzquinamide Biperiden Brexpiprazole Brivaracetam Bupropion Buspirone Butaperazine Butriptyline Cannabidiol - Synthetic form with no other cannabinoid
Brazilian Controlled Drugs and Substances Act
Brazilian_Controlled_Drugs_and_Substances_Act
SSRI antidepressant
tricyclic antidepressants, methamphetamine, amphetamine, MDMA, triptans, buspirone, ginseng, dextromethorphan (DXM), linezolid, tramadol, serotonin–norepinephrine
Fluoxetine
Head movement in rodents upon 5-HT2A receptor activation
5‐HT1A agonist buspirone (20 mg p.o.) markedly attenuates the visual effects of psilocybin in human volunteers.59 Although buspirone failed to completely
Head-twitch_response
Main receptor for most antipsychotic drugs
positron emission tomography studies Typical antipsychotics SV 293 Yohimbine Buspirone – D2 presynaptic autoreceptors (low dose) and postsynaptic D2 receptors
Dopamine_receptor_D2
Antidepressant medication
receptor. Trazodone is a 5-HT1A receptor partial agonist similarly to buspirone and tandospirone but with comparatively greater intrinsic activity. A
Trazodone
Chemical compound
more potent than 8-OH-DPAT and 100-fold more potent than flesinoxan and buspirone. Other 5-HT1A-mediated effects of S-14671 include induction of flat-body
S-14671
Pharmaceutical compound
v t e Anxiolytics (N05B) 5-HT1ARTooltip 5-HT1A receptor agonists Buspirone Gepirone Tandospirone GABAARTooltip GABAA receptor PAMsTooltip positive allosteric
Tasipimidine
- a long-acting CNS stimulant used to treat ADHD Buspar (buspirone) – an anxiolytic used to treat generalized anxiety disorder Belbuca, Buprenex
List of psychotropic medications
List_of_psychotropic_medications
Atypical antipsychotic medication
Kowalki P, Jaskowska J (2012). "An Efficient Synthesis of Aripiprazole, Buspirone and NAN-190 by the Reductive Alkylation of Amines Procedure". Archiv der
Aripiprazole
Pharmaceutical compound
(A-437203; LU-201640) Alpiropride Azapride Bromerguride Bromocriptine Buspirone Carmoxirole Desmethoxyfallypride EEDQ F-15063 F-17464 Fallypride Fananserin
ST-148_(D2L_antagonist)
Chemical compound found in some species of mushrooms
5‐HT1A agonist buspirone (20 mg p.o.) markedly attenuates the visual effects of psilocybin in human volunteers.59 Although buspirone failed to completely
Psilocybin
Gamma-aminobutyric acid analog
uses v t e Anxiolytics (N05B) 5-HT1ARTooltip 5-HT1A receptor agonists Buspirone Gepirone Tandospirone GABAARTooltip GABAA receptor PAMsTooltip positive
Gabapentin
Medication to prevent nausea and vomiting
cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone (F-11440), gepirone, perospirone, tandospirone) Bay R 1531
Ondansetron
Benzodiazepine sedative
withdrawal symptoms after 6 and 12 weeks' treatment with diazepam or buspirone". The British Journal of Psychiatry. 154 (4): 529–34. doi:10.1192/bjp
Diazepam
Pharmaceutical drug classification
Mebutamate N05BC51 Meprobamate, combinations N05BD01 Benzoctamine N05BE01 Buspirone N05BX01 Mephenoxalone N05BX02 Gedocarnil N05BX03 Etifoxine N05BX04 Fabomotizole
ATC_code_N05
Cast of American crime drama TV series
stopped drinking and that the school doctor gave her a prescription for Buspirone, which Hunter comments is given to treat generalized anxiety disorder
List of The Sopranos characters
List_of_The_Sopranos_characters
Pharmaceutical compound
greater efficacy than certain other serotonin 5-HT1A receptor agonists like buspirone and gepirone. It shows favorable pharmacokinetics in rodents. The chemical
NLX-266
Inability to achieve orgasm despite adequate stimulation
may help to relieve SSRI-induced sexual dysfunction. Cyproheptadine, buspirone, stimulants such as amphetamines (including the antidepressant bupropion)
Anorgasmia
SNRI medication
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Duloxetine
Neurodevelopmental disorder
agonists Clonidine Guanfacine Antidepressants Amitriptyline Bupropion Buspirone Desipramine Duloxetine Imipramine Milnacipran Moclobemide Nortriptyline
Attention deficit hyperactivity disorder
Attention_deficit_hyperactivity_disorder
Antidepressant medication
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Mirtazapine
Neurological impairment of voluntary muscle movement
vigabatrin, phosphatidylcholine, acetazolamide, 4-aminopyridine, buspirone, and a combination of coenzyme Q10 and vitamin E. Physical therapy requires
Ataxia
Pharmaceutical compound
hyperlocomotion induced by the serotonin 5-HT1A receptor agonists 8-OH-DPAT and buspirone. The chemical synthesis of GR-46611 has been described. GR-46611 was first
GR-46611
Prodrug
agonists Clonidine Guanfacine Antidepressants Amitriptyline Bupropion Buspirone Desipramine Duloxetine Imipramine Milnacipran Moclobemide Nortriptyline
Omberacetam
Pharmaceutical compound
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Levisoprenaline
Psychiatric disorder defined by chronic depression
include lithium (medication), thyroid hormone augmentation, amisulpride, buspirone, bupropion, guanfacine, stimulants, and mirtazapine. Additionally, if
Dysthymia
Experimental antipsychotic
(A-437203; LU-201640) Alpiropride Azapride Bromerguride Bromocriptine Buspirone Carmoxirole Desmethoxyfallypride EEDQ F-15063 F-17464 Fallypride Fananserin
N-Methylamisulpride
Pharmaceutical compound
(A-437203; LU-201640) Alpiropride Azapride Bromerguride Bromocriptine Buspirone Carmoxirole Desmethoxyfallypride EEDQ F-15063 F-17464 Fallypride Fananserin
Matsupexole
Medical condition
them and are used as treatment by many health professionals. Isoniazid, buspirone hydrochloride, glutethimide, carbamazepine, clonazepam, topiramate, zofran
Intention_tremor
Antidepressant medication
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Vilazodone
Pharmaceutical compound
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Cianergoline
/ dopamine receptor partial agonist and serotonin receptor modulator Buspirone [transdermal] (BuSpar Patch) – serotonin 5-HT1A receptor partial agonist
List of investigational attention deficit hyperactivity disorder drugs
List_of_investigational_attention_deficit_hyperactivity_disorder_drugs
Nasal decongestant
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Xylometazoline
Antihypotensive agent active metabolite
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Desglymidodrine
Medication
Pharmacodynamics v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Milsaperidone
Compounds that bind to and activate adrenergic beta-2 receptors
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Beta2-adrenergic_agonist
Medication used to treat ADHD and depression
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Viloxazine
Pharmaceutical compound
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
CST-3056
Form of psychoactive drugs
cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone (F-11440), gepirone, perospirone, tandospirone) Bay R 1531
Hallucinogenic_snuff
Medication mainly used for depression and smoking cessation
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Bupropion
Central nervous system stimulant
agonists Clonidine Guanfacine Antidepressants Amitriptyline Bupropion Buspirone Desipramine Duloxetine Imipramine Milnacipran Moclobemide Nortriptyline
Methamphetamine
Investigational Parkinson's disease drugs
ionotropic glutamate NMDA receptor agonist [24] Buspirone/zolmitriptan (AV-2860; JM-010) – combination of buspirone (serotonin 5-HT1A receptor agonist and other
List of investigational Parkinson's disease drugs
List_of_investigational_Parkinson's_disease_drugs
Investigational sexual dysfunction drugs
dysfunction, male sexual dysfunction [15] Buspirone/testosterone (Lybridos; testosterone/buspirone) – combination of buspirone (serotonin 5-HT1A receptor agonist
List of investigational sexual dysfunction drugs
List_of_investigational_sexual_dysfunction_drugs
Hormone and medication
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Adrenaline
dronabinol (a trade name for THC) has proven the most effective. The drugs buspirone and rimonabant have shown some success in helping maintain cannabis abstinence
Effects_of_cannabis
Medical condition
including vestibular rehabilitation therapy, medications such as SSRIs or buspirone, and psychotherapy, cognitive behavioral therapy and acceptance and commitment
Persistent postural-perceptual dizziness
Persistent_postural-perceptual_dizziness
Class of medication used to treat depression and other conditions
(azapirones) Serotonin 5-HT1A receptor partial agonism • Other actions Buspirone (off-label) • Gepirone • Tandospirone 1980s Serotonin–norepinephrine reuptake
Antidepressant
Robust antidepressant
cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone (F-11440), gepirone, perospirone, tandospirone) Bay R 1531
NLX-204
Beta blocker medication
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Metoprolol
SNRI antidepressant
might interact with tramadol or other opioids, as well as trazodone and buspirone, so caution is needed while mixing multiple serotonergic agents together
Venlafaxine
Benzodiazepine medication
v t e Anxiolytics (N05B) 5-HT1ARTooltip 5-HT1A receptor agonists Buspirone Gepirone Tandospirone GABAARTooltip GABAA receptor PAMsTooltip positive allosteric
Alprazolam
Sympathomimetic drug
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Norbudrine
Pharmaceutical compound
cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone (F-11440), gepirone, perospirone, tandospirone) Bay R 1531
3,4-Dimethoxyamphetamine
Anti Parkinson medicine
(A-437203; LU-201640) Alpiropride Azapride Bromerguride Bromocriptine Buspirone Carmoxirole Desmethoxyfallypride EEDQ F-15063 F-17464 Fallypride Fananserin
Carbidopa/levodopa/entacapone
Class of chemical compounds
Quipazine (2-piperazin-1-ylquinoline) Many azapirones such as buspirone, gepirone, and tandospirone produce 1-PP as a metabolite. Antianginals
Substituted_piperazine
SSRI antidepressant
Szczawinska K (May 1996). "The effects of pindolol addition to fluvoxamine and buspirone in chronic mild stress model of depression". Behavioural Pharmacology
Fluvoxamine
Clebopride • Domperidone • Metoclopramide • Thiethylperazine Others: Amoxapine • Buspirone • Butaclamol • Ecopipam • N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
List_of_dopaminergic_drugs
Amino acid
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Tyrosine
Chemical compound, Novel psychoactive substance analog, LSD prodrug
cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone (F-11440), gepirone, perospirone, tandospirone) Bay R 1531
1S-LSD
Experimental serotonergic drug
cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone (F-11440), gepirone, perospirone, tandospirone) Bay R 1531
FKW00GA
Class of antidepressants
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Noradrenergic and specific serotonergic antidepressant
Noradrenergic_and_specific_serotonergic_antidepressant
Medication
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Tamsulosin
SSRI antidepressant
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Sertraline
Practice of writing part of a drug's name in upper case letters
but is not limited to: acetaZOLAMIDE vs. acetoHEXAMIDE buPROPion vs. busPIRone chlorproMAZINE vs. chlorproPAMIDE clomiPHENE vs. clomiPRAMINE cycloSERINE
Tall_Man_lettering
Chemical compound
v t e Anxiolytics (N05B) 5-HT1ARTooltip 5-HT1A receptor agonists Buspirone Gepirone Tandospirone GABAARTooltip GABAA receptor PAMsTooltip positive allosteric
Enilospirone
Class of medications
(aripiprazole, brexpiprazole, lurasidone, olanzapine, quetiapine, risperidone) Buspirone Lithium (lithium carbonate, lithium citrate) Thyroid hormones (triiodothyronine
Tricyclic_antidepressant
Psychoactive drug, often called ecstasy
cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone (F-11440), gepirone, perospirone, tandospirone) Bay R 1531
MDMA
Anxiolytic medication
benzodiazepines like lorazepam, alprazolam, and clonazepam and more effective than buspirone for adjustment disorder with anxiety on the basis of directly comparative
Etifoxine
Pharmaceutical compound
(A-437203; LU-201640) Alpiropride Azapride Bromerguride Bromocriptine Buspirone Carmoxirole Desmethoxyfallypride EEDQ F-15063 F-17464 Fallypride Fananserin
Etrabamine
Chemical compound
quebracho, vitamin E) Alkyl nitrites Alprostadil Amantadine Bupropion Buspirone Cyproheptadine Dapoxetine Flibanserin Mirtazapine Moxisylyte Oxytocin
Vardenafil
Dopamine reuptake inhibitor related to modafinil
(A-437203; LU-201640) Alpiropride Azapride Bromerguride Bromocriptine Buspirone Carmoxirole Desmethoxyfallypride EEDQ F-15063 F-17464 Fallypride Fananserin
JJC8-089
BUSPIRONE
BUSPIRONE
BUSPIRONE
BUSPIRONE
Boy/Male
French
From the village.
Girl/Female
American, Australian, British, Chinese, Christian, English, French, German, Latin
From Laurentum; Crowned with Laurel; The Bay; Laurel Plant
Girl/Female
Hindu, Indian
A Caste; Son of Lord Chitragupta
Girl/Female
Arabic, Muslim
Reward; Name of an Early Poetess
Girl/Female
Australian, Welsh
Bird
Boy/Male
American, Australian, British, Celtic, Christian, English, Gaelic, Hawaiian, Hebrew, Irish
Little Pale Green One; Green; Pale One; Pine; Battle; Rule; Soldier
Boy/Male
Tamil
A cuckoo bird
Girl/Female
Indian
God
Girl/Female
Australian
One with Curly Hair
Boy/Male
Hindu
Confined
BUSPIRONE
BUSPIRONE
BUSPIRONE
BUSPIRONE
BUSPIRONE