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Family of proteins
The ErbB family of proteins contains four receptor tyrosine kinases, structurally related to the epidermal growth factor receptor (EGFR), its first discovered
ErbB
Mammalian protein found in humans
tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated from erythroblastic
HER2
Protein found in humans
Receptor tyrosine-protein kinase erbB-3, also known as HER3 (human epidermal growth factor receptor 3), is a membrane bound protein that in humans is encoded
ERBB3
Transmembrane protein
of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her
Epidermal growth factor receptor
Epidermal_growth_factor_receptor
Class of enzymes
different RTK classes have been identified. RTK class I (EGF receptor family) (ErbB family) RTK class II (Insulin receptor family) RTK class III (PDGF receptor
Receptor_tyrosine_kinase
Protein-coding gene in the species Homo sapiens
Receptor tyrosine-protein kinase erbB-4 is an enzyme that in humans is encoded by the ERBB4 gene. Alternatively spliced variants that encode different
ERBB4
p56(lck) MeSH D12.776.624.664.700.642 – receptor, erbb-2 MeSH D12.776.624.664.700.790 – receptor, erbb-3 MeSH D12.776.624.664.700.800 – receptor, macrophage
List_of_MeSH_codes_(D12.776)
Tricyclic antidepressant
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Amitriptyline
Protein-coding gene in the species Homo sapiens
ERBB receptor feedback inhibitor 1 is a protein that in humans is encoded by the ERRFI1 gene. MIG6 is a Cytoplasmic protein whose expression is upregulated
ERRFI1
Primary male sex hormone
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Testosterone
Corticosteroid medication
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Dexamethasone
German pharmaceutical company
cell lung cancer (NSCLC) / ovarian cancer Phase III Afatinib Irreversible ErbB family blocker Breast cancer / head and neck cancer. Already approved for
Boehringer_Ingelheim
TrkA and TrkB positive modulator
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
ACD856
Protein that stimulates cell division and differentiation
EJ (July 2002). "Role of the N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display". Biochemistry. 41 (27): 8732–41.
Epidermal_growth_factor
School in Keilor Downs, Victoria, Australia
branched out to other universities, such as Emir's Royal Bosnian Barracks or ERBB for short. "Home". kdc.vic.edu.au. "Keilor Downs College - Issue 17: VCE
Keilor_Downs_College
Protein-coding gene in the species Homo sapiens
all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms
Neuregulin_1
Monoclonal antibody
agents (L01) CI monoclonal antibodies ("-mab") Receptor tyrosine kinase ErbB: HER1/EGFR (Cetuximab Panitumumab) HER2/neu (Pertuzumab Trastuzumab (+hyaluronidase)
Mosunetuzumab
Medication for macular degeneration
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Faricimab
Mammalian protein found in humans
PMID 20152769. Bánkfalvi A (November 2000). "Comparative methodological analysis of erbB-2/HER-2 gene dosage, chromosomal copy number and protein overexpression in
Ki-67_(protein)
Peptide hormone
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Insulin
Medication
agents (L01) CI monoclonal antibodies ("-mab") Receptor tyrosine kinase ErbB: HER1/EGFR (Cetuximab Panitumumab) HER2/neu (Pertuzumab Trastuzumab (+hyaluronidase)
Elranatamab
interfaces of homologous proteins identified by ProtCID -- similar homodimers of ERBB kinases (EGFR, ERBB2, ERBB4) associated with kinase activation. Each monomer
ProtCID
System of communication
Michael; Lerdrup, Mads; van Deurs, Bo (May 2008). "Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer". Histochemistry and Cell Biology
Cell_signaling
Anti-cancer medication
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Dabrafenib
Spanish cancer researcher and reserve astronaut
dissertation focused on mechanisms of resistance to antibody-drug conjugates in ErbB receptors and it won her the university's Outstanding Doctorate Award the
Sara_García_Alonso
Chemical compound
inhibitor with activity against EGFR (IC50 0.8 nM), HER-2 (IC50 19 nM) and ErbB-4 (IC50 7 nM). By 2015, Pfizer had discontinued development of the drug.
Canertinib
Medication used for cancer
inhibitor. The target protein (EGFR) is a member of a family of receptors (ErbB) which includes Her1(EGFR), Her2(erb-B2), Her3(erb-B3) and Her4 (Erb-B4)
Gefitinib
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Eutropoflavin
Mammalian protein found in humans
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Nerve_growth_factor
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Dihexa
Protein that stimulates red blood cell production
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Erythropoietin
Synthetic protein
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
IGF-1_LR3
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Imatinib
Medication
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Bevacizumab
Pharmaceutical drug
the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans). Panitumumab is manufactured by Amgen and was originally
Panitumumab
Form of mimicry in plants
result is long-lasting hypersensitivity in bitten mammals, implying that ErbB is involved in signalling mammalian pain. The mechanism is, according to
Gilbertian_mimicry
Signaling glycoprotein regulating cell proliferation
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Platelet-derived growth factor
Platelet-derived_growth_factor
Protein-coding gene in the species Homo sapiens
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
FGF19
Mammalian protein found in humans
(August 2002). "Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1". Oncogene. 21 (36): 5609–18. doi:10.1038/sj.onc
Androgen_receptor
Group of signal transduction pathways involved in embryonic development
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Wnt_signaling_pathway
Protein found in humans
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Insulin-like_growth_factor_1
Protein-coding gene in the species Homo sapiens
protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus"
YAP1
Drug typically used in cancer treatment
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Tyrosine_kinase_inhibitor
Generating of neurons from neural stem cells in adults
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Adult_neurogenesis
Chemical compound used in the treatment of tumors
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Toceranib
Medication
signaling is stronger and longer acting compared to heterodimers between other ERBB members. It has been reported that Trastuzumab induces the formation of
Trastuzumab
Cancer medication
inhibition in the treatment of breast cancer: initial experience with the EGFR/ErbB-2 inhibitor lapatinib". The Oncologist. 9 (Suppl 3): 10–15. doi:10.1634/theoncologist
Lapatinib
Protein and coding gene in humans
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Tropomyosin_receptor_kinase_B
Class of proteins
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Hemopoietic_growth_factor
Class of enzymes
(protein-serine/threonine kinases). This enzyme participates in 14 metabolic pathways: erbb signaling pathway, cell cycle, wnt signaling pathway, hedgehog signaling
Tau-protein_kinase
Drug designed to treat obesity
apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene". Annals of Oncology. 16 (8): 1253–1267. doi:10.1093/annonc/mdi239
Orlistat
Protein-coding gene in the species Homo sapiens
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
EPHA10
Protein or other substance that stimulates cellular proliferation
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Growth_factor
Chemical compound
(July 2004). "Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells". Proc. Natl. Acad. Sci. U.S.A
Cerulenin
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Neratinib
Mammalian protein found in Mus musculus
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
FGF15
Monoclonal antibody
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Futuximab
Type of inhibitor
wild-type EGFR that are expected to lead to a wider therapeutic index. The pan-ErbB inhibitor Neratinib was approved in the US in 2017 and in the EU in 2018
Targeted_covalent_inhibitors
Transcription factor
including the ability to correct abnormal gene expression profiles (e.g., erbB-2 overexpression in human adenocarcinomas) and anti-retrovirals (e.g. HIV-1)
Zinc finger transcription factor
Zinc_finger_transcription_factor
Chemical compound
Develop Core Technologies". BusinessKorea. Roskoski R (September 2014). "ErbB/HER protein-tyrosine kinases: Structures and small molecule inhibitors".
Poziotinib
Pharmaceutical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
E2511
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Nintedanib
Class of drugs used to treat malignant tumors
(epidermal growth factor receptor) expression Selectively binds to HER-2 (ErbB-2), blocking HER-2-mediated PI3K and MAPK signaling pathways, inhibiting
Antineoplastic
Protein-coding gene in the species Homo sapiens
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Fibroblast growth factor receptor 4
Fibroblast_growth_factor_receptor_4
Protein-coding gene in the species Homo sapiens
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Angiopoietin_4
Monoclonal antibody
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Pegfilgrastim
Combination drug
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Mecasermin_rinfabate
Drug for the treatment of lung carninoma
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Dacomitinib
Cell signaling pathway
Schulze WX, Deng L, Mann M (2005). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Molecular Systems Biology. 1 (1): 2005.0008. doi:10
MAPK/ERK_pathway
Medication which blocks growth of blood vessels
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Anti-VEGF
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Fulranumab
Transmembrane receptors involved in cellular adhesion and signalling
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Integrin
Mammalian protein found in humans
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
C-fos-induced_growth_factor
Protein capable of worsening malignant diseases
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Hepatoma-derived growth factor
Hepatoma-derived_growth_factor
Proteins similar to insulin that stimulate cell proliferation
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Insulin-like_growth_factor
Protein involved in blood vessel growth
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Vascular endothelial growth factor
Vascular_endothelial_growth_factor
Protein-coding gene in the species Homo sapiens
after its similarity to v-erbA (P03373), a helper of an oncoprotein called v-erbB in avian erythroblastosis virus. Comparatively little is known about ear-2
V-erbA-related_gene
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
ANA-12
Hypothesis that decreased glutamatergic signalling is involved in schizophrenia
Research done on mice in early 2009 has shown that when the neuregulin-1\ErbB postsynaptic receptor genes are deleted, the dendritic spines of glutamate
Glutamate hypothesis of schizophrenia
Glutamate_hypothesis_of_schizophrenia
Pharmaceutical drug
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Trastuzumab_emtansine
ALK inhibitor for treatment of non-small-cell lung cancer
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Crizotinib
Family of proteins involved in anatomical development
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Fibroblast_growth_factor
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Axitinib
points at which the model could be further extended. A more recent model of ErbB receptor signalling even accounts for more than one googol ( 10 100 {\displaystyle
Multi-state modeling of biomolecules
Multi-state_modeling_of_biomolecules
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Crenolanib
Medical condition
carboxypeptidase II erbB-3 receptor Early prostate cancer antigen-2 SPINK1 GOLM1 PCA3 TMPRSS2 hPG80 Germ cell tumor NANOG Bladder cancer erbB-3 receptor NMP22
Germinoma
Pharmaceutical drug
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Alacizumab_pegol
adrenocortical carcinoma patients CD340 Receptor tyrosine-protein kinase erbB-2, HER2 (human epidermal growth factor receptor 2) or HER2/neu. Overexpression
List of human clusters of differentiation
List_of_human_clusters_of_differentiation
Mammalian protein found in Homo sapiens
Garcia RA, Vasudevan K, Buonanno A (March 2000). "The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses". Proc. Natl
DLG4
Protein-coding gene in the species Homo sapiens
Graus-Porta D, Beerli RR, Rohrer J, Gay B, Hynes NE (September 1998). "ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization
GRB2
Chemical compound, used as a medication to treat lung cancer
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Osimertinib
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Tepotinib
Protein found in humans
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Fibroblast growth factor receptor 1
Fibroblast_growth_factor_receptor_1
Family of proteins
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Neurotrophin
Family of four EGF proteins
transcription initiation sites. In general, they bind to and activate the erbB family of receptor tyrosine kinases (erbB2 (HER2), erbB3 (HER3), and erbB4
Neuregulin
Protein-coding gene in the species Homo sapiens
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
EPHA8
Growth factor and signaling protein otherwise known as FGF2
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Fibroblast_growth_factor_2
Chemical compound
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Tropoflavin
Protein found in humans
Nesvacumab (against angiopoietin 2) CNTF Agonists: Axokine CNTF Dapiclermin EGF (ErbB) EGF (ErbB1/HER1) Agonists: Amphiregulin Betacellulin EGF (urogastrone) Epigen
Brain-derived neurotrophic factor
Brain-derived_neurotrophic_factor
Protein-coding gene in the species Homo sapiens
Schulze WX, Deng L, Mann M (2005). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Molecular Systems Biology. 1 (1) 2005.0008. doi:10
STAT5A
ERBB
ERBB
ERBB
ERBB
Boy/Male
Hindu
Goddess Parvati, Goddess of desires
Boy/Male
Hindu, Indian
Religious Thought
Girl/Female
Hindu, Indian
Completed
Male
Hebrew
(גְּדַלְיָהוּ) Variant form of Hebrew Gedalyah, GEDALYAHU means "God is great."
Boy/Male
Afghan, American, Arabic
Bone-setter; Repairer
Girl/Female
Christian & English(British/American/Australian)
Old Name of Ireland
Girl/Female
Hindu
Cool like the Moon
Boy/Male
Gaelic American Irish English
Servant.
Boy/Male
Hindu
Goddess Lakshmi
Boy/Male
Hindu
ERBB
ERBB
ERBB
ERBB
ERBB