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Class of enzymes which split esters into an acid and alcohol via hydrolysis
In biochemistry, an esterase is a class of enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis (and
Esterase
Test for white blood cells in urine
Leukocyte esterase is a type of esterase enzyme released by white blood cells (leukocytes), particularly neutrophils, when they are activated or recruited
Leukocyte_esterase
Topics referred to by the same term
A-esterase may refer to one of two enzymes: Arylesterase Aryldialkylphosphatase This disambiguation page lists articles associated with the title A-esterase
A-esterase
Esterase that lyses choline-based esters
The enzyme cholinesterase (EC 3.1.1.8, choline esterase; systematic name acylcholine acylhydrolase) catalyses the hydrolysis of choline-based esters, several
Cholinesterase
Histological staining compound
α-Naphthyl butyrate esterase, also referred to as naphthyl butyrate esterase or butyrate esterase, is a histological stain specific for white blood cells
Butyrate_esterase
The enzyme sinapine esterase (EC 3.1.1.49) catalyzes the hydrolysis reaction: sinapine H2O sinapinic acid + choline Sinapine and sinapinic
Sinapine_esterase
Class of enzymes
The enzyme acetylajmaline esterase (EC 3.1.1.80, AAE, 2β(R)-17-O-acetylajmalan:acetylesterase, acetylajmalan esterase; systematic name 17-O-acetylajmaline
Acetylajmaline_esterase
Glycoprotein present in some enveloped viruses
Hemagglutinin esterase (HEs) is a glycoprotein that certain enveloped viruses possess and use as an invading mechanism. HEs helps in the attachment and
Hemagglutinin_esterase
The enzyme feruloyl esterase (EC 3.1.1.73) catalyzes the reaction feruloyl-polysaccharide + H2O ⇌ {\displaystyle \rightleftharpoons } ferulate + polysaccharide
Feruloyl_esterase
Drugs that inhibit acetylcholinesterase
contamination with the organophosphate. It is believed that the neuropathy target esterase (NTE) is affected by the organophosphate which induces the disease. However
Acetylcholinesterase inhibitor
Acetylcholinesterase_inhibitor
The enzyme sterol esterase (EC 3.1.1.13) catalyzes the reaction a sterol ester + H2O ⇌ {\displaystyle \rightleftharpoons } a sterol + a fatty acid This
Sterol_esterase
Index of enzymes associated with the same name
Esterase D may refer to: Methylumbelliferyl-acetate deacetylase, an enzyme Carboxylesterase, an enzyme This set index page lists enzyme articles associated
Esterase_D
Medical condition
Acquired C1 esterase inhibitor deficiency, also referred to as acquired angioedema (AAE), is a rare medical condition that presents as body swelling that
Acquired C1 esterase inhibitor deficiency
Acquired_C1_esterase_inhibitor_deficiency
Disorder resulting in severe swelling
in hereditary angioneurotic edema: Absence of serum inhibitor of C' 1-esterase". Am. J. Med. 35 (1). The American Journal of Medicine: 37–44. doi:10
Hereditary_angioedema
Disease characterized by rapid swelling
related to bradykinin may occur due to an inherited problem known as C1 esterase inhibitor deficiency, medications known as angiotensin-converting enzyme
Angioedema
Class of enzymes which use water to break a chemical bond
of hydrolase enzymes are esterases including lipases, phosphatases, glycosidases, peptidases, and nucleosidases. Esterases cleave ester bonds in lipids
Hydrolase
Protein-coding gene in the species Homo sapiens
Neuropathy target esterase, also known as patatin-like phospholipase domain-containing protein 6 (PNPLA6), is an esterase enzyme that in humans is encoded
Neuropathy_target_esterase
Class of enzymes
The chloride cocaine esterase (EC 3.1.1.84, CocE, hCE2, hCE-2, human carboxylesterase 2; systematic name cocaine benzoylhydrolase) catalyses the reaction
Cocaine_esterase
Primary cholinesterase in the body
discussed at Cholinesterase § Types and nomenclature. For acetylcholine esterase (AChE), reversible inhibitors are those that do not irreversibly bond to
Acetylcholinesterase
Protein-coding gene in the species Homo sapiens
Neurexophilin and PC-esterase domain family member 2 is a protein that in humans is encoded by the NXPE2 gene. GRCh38: Ensembl release 89: ENSG00000204361
Neurexophilin and PC-esterase domain family member 2
Neurexophilin_and_PC-esterase_domain_family_member_2
Class of enzymes
The enzyme acetylxylan esterase (EC 3.1.1.72) catalyzes the deacetylation of xylans and xylo-oligosaccharides. This enzyme belongs to the family of hydrolases
Acetylxylan_esterase
Class of enzymes
aspirin esterase, acetylsalicylic acid esterase, and aspirin hydrolase. Ali B, Kaur S (1983). "Mammalian tissue acetylsalicylic acid esterase(s): identification
Acetylsalicylate_deacetylase
Mammalian protein found in humans
C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement
C1-inhibitor
Chemical reaction
pig liver esterase is the enantioselective conversion of an ester to a carboxylic acid through the action of the enzyme pig liver esterase (EC 3.1.1.1)
Asymmetric ester hydrolysis with pig-liver esterase
Asymmetric_ester_hydrolysis_with_pig-liver_esterase
hormone esterase (EC 3.1.1.59, systematic name methyl-(2E,6E,10R)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase, JH esterase) catalyzes
Juvenile-hormone_esterase
Class of enzymes
ali-esterase, B-esterase, butyrate esterase, butyryl esterase, carboxylesterase 1 carboxylesterase 2 carboxylesterase 3 esterase A, esterase B, esterase D
Carboxylesterase
Class of enzymes
The enzyme 4-methyloxaloacetate esterase (EC 3.1.1.44) catalyzes the reaction oxaloacetate 4-methyl ester + H2O ⇌ {\displaystyle \rightleftharpoons } oxaloacetate
4-methyloxaloacetate_esterase
Class of enzymes which split acetic esters into alcohols and acetates
ester bonds (esterases). The systematic name of this enzyme class is acetic-ester acetylhydrolase. Other names in common use include C-esterase (in animal
Acetylesterase
Protein-coding gene in the species Homo sapiens
CES1 gene. The protein is also historically known as serine esterase 1 (SES1), monocyte esterase and cholesterol ester hydrolase (CEH). Three transcript variants
Carboxylesterase_1
Species of virus
N-acetyl-9-O-acetylneuraminic acid receptor. It has the hemagglutinin esterase (HE) gene, which distinguishes it as a member of the genus Betacoronavirus
Human_coronavirus_HKU1
Chemical compound
prokinetic benzamide derivative. These drugs inhibit dopamine and acetylcholine esterase enzyme and have a gastrokinetic effect. Itopride is indicated for the treatment
Itopride
Species of virus
an additional shorter spike-like surface protein called hemagglutinin esterase (HE) as well as the larger coronavirus spike protein. de Groot, R.J; et al
Betacoronavirus_1
The enzyme mycophenolic acid acyl-glucuronide esterase (EC 3.1.1.93, mycophenolic acid acyl-glucuronide deglucuronidase; AcMPAG deglucuronidase; systematic
Mycophenolic acid acyl-glucuronide esterase
Mycophenolic_acid_acyl-glucuronide_esterase
Chemical agents that inhibit Cholinesterase
Cholinesterase inhibitors (ChEIs), also known as anti-cholinesterase, are chemicals that prevent the breakdown of the neurotransmitter acetylcholine or
Cholinesterase_inhibitor
Diagnostic tool used in urinalysis
contain esterases. Neutrophil granulocytes are the leukocytes most commonly associated with urinary infections. A positive test for leukocyte esterase normally
Urine_test_strip
Class of enzymes
include diacetoxybutynylbithiophene acetate esterase, and 3,4-diacetoxybutinylbithiophene:4-acetate esterase. Pensl R, Suetfeld R (1985). "Occurrence of
5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase
5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene_deacetylase
Class of enzymes
carboxylesterase, pyrethroid-hydrolysing esterase, pyrethroid-hydrolyzing esterase, pyrethroid-selective esterase, pyrethroid-cleaving enzyme, permethrinase
Pyrethroid_hydrolase
Protein-coding gene in humans
C1r subcomponent (EC 3.4.21.41, activated complement C1r, C overbar 1r esterase, C1r) is a protein involved in the complement system of the innate immune
Complement_component_1r
Enzyme
The enzyme fumonisin B1 esterase (EC 3.1.1.87, fumD (gene); systematic name fumonisin B1 acylhydrolase) catalyses the reaction fumonisin B1 + 2 H2O ⇌ {\displaystyle
Fumonisin_B1_esterase
Protein found in humans
Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system
Complement_component_1s
Chemical compound (nerve agent)
inhibits AChE, but it is also a substrate for other esterases. Reaction of soman with these esterases allows for the detoxication of the compound. No metabolic
Soman
Species of scorpion
that C. vittatus venom contains the enzymes alkaline phosphatase, esterase, esterase lipase, acid phosphatase, and phospholipase A. While a C. vittatus
Striped_bark_scorpion
Class of enzymes
use include acetoxybutynylbithiophene esterase, and 5-(4-acetoxy-1-butynyl)-2,2′-bithiophene:acetate esterase. Granander J, Sott R, Hilmersson G (2006)
Acetoxybutynylbithiophene deacetylase
Acetoxybutynylbithiophene_deacetylase
Chemical compound
producing masculinization and suitable for androgen replacement therapy. Esterase enzymes break the ester bond in testosterone enanthate, releasing free
Testosterone_enanthate
In enzymology, a retinyl-palmitate esterase (EC 3.1.1.21) is an enzyme that catalyzes the chemical reaction. retinyl palmitate + H2O ⇌ {\displaystyle \rightleftharpoons
Retinyl-palmitate_esterase
Class of enzymes
acylhydrolase. Other names in common use include 11-cis-retinol palmitate esterase, and RPH. This enzyme participates in retinol metabolism. This enzyme has
11-cis-retinyl-palmitate hydrolase
11-cis-retinyl-palmitate_hydrolase
The enzyme polyneuridine-aldehyde esterase (EC 3.1.1.78) catalyzes the following reaction: polyneuridine aldehyde + H2O ⇌ {\displaystyle \rightleftharpoons
Polyneuridine-aldehyde esterase
Polyneuridine-aldehyde_esterase
Potentially fatal complication of pregnancy
activate complement. Additionally, another study showed activity levels of C1 esterase inhibitor, a key regulator of the complement system, are significantly
Amniotic_fluid_embolism
Anatomic structure in pit vipers
adenosine triphosphate, monoamine oxidase, generalized esterases, and acetylcholine esterase have also been found in it. When prey comes into range,
Loreal_pit
Protein-coding gene in the species Homo sapiens
Paraoxonase 1 (PON1) also known as Serum paraoxonase and arylesterase 1, A esterase, homocysteine thiolactonase or serum aryldialkylphosphatase 1, is an enzyme
PON1
Class of enzymes
Factor D (EC 3.4.21.46, C3 proactivator convertase, properdin factor D esterase, factor D (complement), complement factor D, CFD, adipsin) is a protein
Factor_D
Class of enzymes which cleave fats via hydrolysis
these are usually treated separately from "conventional" lipases. Unlike esterases, which function in water, lipases "are activated only when adsorbed to
Lipase
Form of L-carnitine
dietary supplement. Acetylcarnitine is broken down in the blood by plasma esterases to carnitine which is used by the body to transport fatty acids into the
Acetylcarnitine
Chemical compound
complex + HF The median lethal dose between 150–215 mg/kg (acetylcholine esterase inactivator). PMSF should be handled only inside a fume hood and while
PMSF
Topics referred to by the same term
certain organisms Helium, symbol He, a chemical element Hemagglutinin esterase, a viral protein Hematoxylin and eosin stain, a popular staining method
He
Pharmaceutical drug
treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. It is not effective in angioedema caused by medication
Icatibant
Birth defect in which the intestine lacks certain nerves
Histopathology of Hirschsprung disease showing abnormal acetylcholine esterase (AchE)-positive nerve fibers (brown) in the mucosa Specialty Medical genetics
Hirschsprung's_disease
Class of enzymes
organophosphate hydrolase, parathion hydrolase, paraoxonase, and parathion aryl esterase; systematic name aryltriphosphate dialkylphosphohydrolase) is a metalloenzyme
Aryldialkylphosphatase
Compound that is metabolized into a pharmacologically active drug
aglycone. For example, salicin is a β-D-glucopyranoside that is cleaved by esterases to release salicylic acid. Aspirin (acetylsalicylic acid), first made
Prodrug
Class of enzymes
PETases are an esterase class of enzymes that catalyze the breakdown (via hydrolysis) of polyethylene terephthalate (PET) plastic to monomeric mono-2-hydroxyethyl
PETase
Class of enzymes which split thiol esters into an acid and alcohol
which belong to the esterase family. Esterases, in turn, are one type of the several hydrolases known. Thioesterases exhibit esterase activity (splitting
Thioesterase
Chemical compound
ripening of fruit. In over-ripe fruits, due to the presence of pectic methyl esterase enzyme, the pectin gets largely converted to pectic acid which is water-insoluble
Pectic_acid
Family of evolutionarily related proteins
eukaryotes have many distinct esterases. The different types include those that act on carboxylic esters (EC 3.1.1). Carboxyl-esterases have been classified into
Carboxylesterase_type_B
Species of virus
Embecovirus, an additional shorter spike protein called hemagglutinin-esterase (HE). Genetic and antigenic analyses reveal significant similarities between
Human_coronavirus_OC43
Opioid analgesic drug
controlled-substances laws. Diacetyldihydromorphine is quickly metabolized by plasma esterase enzymes into dihydromorphine, in the same way that diamorphine is metabolized
Diacetyldihydromorphine
Enzyme hydrolysing long-chain fatty esters
"Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population". Journal of Human
Carboxylesterase_2
The enzyme Pimelyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85, BioH; systematic name pimelyl-[acyl-carrier protein] methyl ester hydrolase
Pimelyl-(acyl-carrier protein) methyl ester esterase
Pimelyl-(acyl-carrier_protein)_methyl_ester_esterase
Psychedelic drug
psilocybin. Psilocin ester prodrugs like 4-AcO-DMT are cleaved into psilocin by esterase enzymes. A 2025 in-vitro study examined the stability and metabolism of
4-AcO-DMT
Class of enzymes
The enzyme 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) catalyzes the reaction 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O ⇌ {\displaystyle
1-alkyl-2-acetylglycerophosphocholine esterase
1-alkyl-2-acetylglycerophosphocholine_esterase
Chemical compound found in some species of mushrooms
stomach or the actions of alkaline phosphatase (ALP) and non-specific esterases in tissues and fluids. Psilocin is demethylated and oxidatively deaminated
Psilocybin
Pharmaceutical compound
psilocybin (4-PO-DMT). The drug is cleaved into psilocin by non-specific esterases. O-Glutarylpsilocin was first described in the scientific literature in
RE-109
Chemical compound
ester of benzylpenicillin, is a prodrug processed to benzylpenicillin by esterases. It has no detectable teratogenic risk to the fetus. Agersborg HP, Batchelor
Penamecillin
Topics referred to by the same term
PLE may refer to: Photoluminescence excitation Pig-liver esterase Pittsburgh and Lake Erie Railroad, P&LE Polymorphous light eruption, a skin condition
PLE
Antihypertensive drug of the calcium channel blocker class
a half-life of approximately one minute. It is rapidly inactivated by esterases. It was approved by the United States Food and Drug Administration on
Clevidipine
The enzyme α-amino-acid esterase (EC 3.1.1.43) catalyzes the reaction an α-amino acid ester + H2O ⇌ {\displaystyle \rightleftharpoons } an α-amino acid
Alpha-amino-acid_esterase
Region of the human brain
cord via reticulospinal tract.[citation needed] Physostigmine, a choline-esterase inhibitor, elevates endogenous levels of acetylcholine and causes a rise
Rostral_ventrolateral_medulla
Enzyme database
hydrolases, glycosyltransferases, polysaccharide lyases, carbohydrate esterases, and non-catalytic carbohydrate-binding modules. The CAZy database also
CAZy
Protein family
lysophopholipase L2, lysophospholipase transacylase, neuropathy target esterase, NTE, NTE-LysoPLA, and NTE-lysophospholipase. This enzyme participates
Lysophospholipase
Class of enzymes
The enzyme methylumbelliferyl-acetate deacetylase (EC 3.1.1.56, esterase D) catalyzes the reaction 4-methylumbelliferyl acetate + H2O ⇌ {\displaystyle
Methylumbelliferyl-acetate deacetylase
Methylumbelliferyl-acetate_deacetylase
Set of three coordinated amino acids
found in hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases, lipases and β-lactamases). An acid-base-nucleophile triad is
Catalytic_triad
Mammalian protein found in Homo sapiens
Colwell N, et al. (1992). "Structure of the human pancreatic cholesterol esterase gene". Biochemistry. 31 (26): 6077–81. doi:10.1021/bi00141a017. PMID 1627550
Bile_salt-dependent_lipase
Class of enzymes
degrades triglycerides into two fatty acids and a monoglyceride Sterol esterase Phospholipase Several nucleases that degrade nucleic acids, like DNAase
Digestive_enzyme
Species of bacterium
Streptomyces capillispiralis produces cephalosporin-C4-carboxymethyl-esterase. List of Streptomyces species LPSN bacterio.net MERTZ, F. P.; HIGGENS,
Streptomyces_capillispiralis
Tropane alkaloid and stimulant drug
elimination half-life of 0.7–1.5 hours and is extensively metabolized by plasma esterases and also by liver cholinesterases, with only about 1% excreted unchanged
Cocaine
Medical condition
Cholinergic urticaria Aquagenic urticaria Other urticaria Acquired C1 esterase inhibitor deficiency Adrenergic urticaria Autoimmune urticaria Exercise
Annular_erythema_of_infancy
Psychoactive substance found in plants in the family Apocynaceae
(N10OMT) to produce (-)-voacangine. Polyneudridine aldehyde esterase-like 1 (PNAE1) and a spontaneous decarboxylation can convert (-)-voacangine
Ibogaine
Genus of viruses in the family Orthomyxoviridae
than the HI test. Because only Influenza viruses C and D produce esterase, In Situ Esterase Assays provide a quick and inexpensive method of detecting just
Influenza_C_virus
Pharmaceutical compound
esters to rat brain synaptosomes and the influence of bioactivation by esterases". Arzneimittel-Forschung. 31 (6): 979–981. PMID 7196245. Cesari A, Balzano
Oxazepam_hemisuccinate
Drugs used to achieve relief from pain
Mu opioid. IV. Protein binding = 70%; hydrolysed by blood and tissue esterases; half-life = 20 min; excretion = urine (95%). Anaesthesia maintenance
Analgesic
Protein family
methyl-accepting chemotaxis protein methyl-esterase, CheB methylesterase, methylesterase CheB, protein methyl-esterase, protein carboxyl methylesterase, PME
Protein-glutamate methylesterase
Protein-glutamate_methylesterase
Development of hives after contact with water
Cholinergic urticaria Aquagenic urticaria Other urticaria Acquired C1 esterase inhibitor deficiency Adrenergic urticaria Autoimmune urticaria Exercise
Aquagenic_urticaria
Describes a new class of consumer health testing
✓ ✓ ✓ ✓ Monocytes % ✓ ✓ ✓ ✓ ✓ Band Neutrophils % ✓ Advanced Leukocyte Esterase Advanced Immature granulocytes (IG) ✓ ✓ Immature granulocytes % (IG%) ✓
Direct-to-consumer blood testing
Direct-to-consumer_blood_testing
Anti-full body paralysis drug treatment
Metabolism Slow hydrolysis by acetylcholinesterase and also by plasma esterases Onset of action Within 10-20 min (injection), with 4 hrs (by mouth) [citation
Neostigmine
Protein-coding gene in the species Homo sapiens
Gene ontology Molecular function 1-alkyl-2-acetylglycerophosphocholine esterase activity platelet-activating factor acetyltransferase activity protein
PAFAH1B3
aromatic rings of digallate (depsidase activity), tannase may also have an esterase activity (hydrolysis of terminal ester functional groups that are attached
Tannase
Mammalian protein found in Homo sapiens
lipase A, lysosomal acid, cholesterol esterase (Wolman disease) Identifiers Symbol LIPA NCBI gene 3988 HGNC 6617 OMIM 278000 RefSeq NM_000235 UniProt P38571
Lysosomal_lipase
Array of tests performed on urine
ketones, bilirubin, urobilinogen, blood, white blood cells (leukocyte esterase), protein, nitrite, pH, and specific gravity. Nitrite is reported as negative
Urinalysis
Chemical compound
After entering cells by diffusion, CFDA-SE is cleaved by intracellular esterase enzymes to form CFSE. As its reactive succinimidyl ester group is unmodified
Carboxyfluorescein diacetate succinimidyl ester
Carboxyfluorescein_diacetate_succinimidyl_ester
Antiviral medication
greater oral bioavailability (about 55%) than aciclovir. It is converted by esterases to the active drug, aciclovir, and the amino acid valine via hepatic first-pass
Valaciclovir
Protein-coding gene in the species Homo sapiens
carboxylic ester hydrolase activity sterol esterase activity triglyceride lipase activity methyl indole-3-acetate esterase activity Cellular component endoplasmic
Carboxylesterase_3
ESTERASE
ESTERASE
ESTERASE
ESTERASE
Girl/Female
Bengali, Hindu, Indian, Kannada, Malayalam, Marathi, Sindhi, Telugu
Flower
Boy/Male
Arabic, Australian, Muslim
Comfort; Sweet Smelling Plant
Boy/Male
Indian
Ocean of knowledge
Boy/Male
Indian, Kannada
Lord Shiva
Girl/Female
Indian
Lustrous
Female
Arthurian
, ice-fighter.
Boy/Male
Arabic, Muslim
Servant of the Most Holy (Allah)
Girl/Female
Hindu
Another name of river Kaveri
Boy/Male
Hindu, Indian, Sanskrit
Born of the Sun
Boy/Male
Gujarati, Hindu, Indian, Sanskrit
Which can Hear
ESTERASE
ESTERASE
ESTERASE
ESTERASE
ESTERASE