Reference for GLOBOZOOSPERMIA. Search for GLOBOZOOSPERMIA

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GLOBOZOOSPERMIA

Globozoospermia

Medical condition

Globozoospermia is a rare and severe form of monomorphic teratozoospermia. This means that the spermatozoa show the same abnormality, and over 85% of

Globozoospermia

Teratospermia

Medical condition of mis-shaped sperm

often associated with decreased normal forms (morphology). In cases of globozoospermia (sperm with round heads), the Golgi apparatus is not transformed into

Teratospermia

Acrosome

Organelle of sperm cells

FITC-ConA, or fluoresceinated antibody such as FITC-CD46. In the case of globozoospermia (sperm with round heads), the Golgi apparatus is not transformed into

Acrosome

Inner nuclear membrane protein

Protein embedded in inner membrane of nuclear envelope

"Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus"

Inner nuclear membrane protein

Inner_nuclear_membrane_protein

A23187

Chemical compound

of low fertilization rate after ICSI procedure, particularly with Globozoospermia (Round Head sperm syndrome), Ca Ionophore will replace absence of sperm

A23187

SPATA16

Reproductive gene and associated protein

gene are associated with male infertility in humans and can cause globozoospermia, which are round-headed sperm without acrosomes. Sperm with incorrect

SPATA16

DPY19L2

Protein-coding gene in humans

"MLPA and sequence analysis of DPY19L2 reveals point mutations causing globozoospermia". Human Reproduction. 27 (8): 2549–58. doi:10.1093/humrep/des160. PMID 22627659

DPY19L2

Oocyte activation

Processes in fertilization

retrieval Severe teratozoospermia Severe oligoasthenoteratozoospermia Globozoospermia Testicular sperm extraction (MicroTESE) Previous fertilization failure

Oocyte activation

Oocyte_activation

C19Orf81

Human protein and gene

https://doi.org/10.1042/BJ20021469 Xu, X., Toselli, P., Russell, L. et al. Globozoospermia in mice lacking the casein kinase II α′ catalytic subunit. Nat Genet

C19Orf81

Casein kinase 2

Protein

PMID 27306791. Xu X, Toselli PA, Russell LD, Seldin DC (September 1999). "Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit". Nature

Casein kinase 2

Casein_kinase_2

List of OMIM disorder codes

137750; CYP1B1 Glioblastoma, somatic; 137800; ERBB2 Globozoospermia; 102530; GOPC Globozoospermia; 102530; SPATA16 Glomerulocystic kidney disease with

List of OMIM disorder codes

List_of_OMIM_disorder_codes