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KAT2A

  • KAT2A
  • Protein-coding gene in the species Homo sapiens

    Histone acetyltransferase KAT2A is an enzyme that in humans is encoded by the KAT2A gene. KAT2A also acetylates non-histone proteins, including the transcription

    KAT2A

    KAT2A

    KAT2A

  • TBP-associated factor
  • Protein domains

    TAF-containing complex), and STAGA (SPT3-TAF9-GCN5L acetylase). PCAF (GCN5) and KAT2A (GCN5L) are two human homologs of the yeast Gcn5. TAF8, TAF10, and SPT7L

    TBP-associated factor

    TBP-associated factor

    TBP-associated_factor

  • Zhimin Lu
  • Chinese-American biologist and oncologist

    translocates into the nucleus and associates with KAT2A, which known as a histone acetyltransferase. KAT2A gains a new function and acts as a histone H3 succinyltransferase

    Zhimin Lu

    Zhimin_Lu

  • Lysine malonylation
  • Post-translational modification

    certain lysine acetyltransferases (KATs) may also catalyze malonylation. KAT2A (GCN5) has been experimentally linked to histone malonylation and is currently

    Lysine malonylation

    Lysine malonylation

    Lysine_malonylation

  • PAX6
  • Protein-coding gene in humans

    functions. Post-translational regulation of PAX6 includes acetylation by KAT2A, which promotes its ubiquitination and proteasomal degradation, thereby

    PAX6

    PAX6

    PAX6

  • Neural stem cell
  • Precursor cells of neurons and glia during embryonic development

    transcription factors. For example, acetylation of the transcription factor PAX6 by KAT2A has been shown to promote its ubiquitination and proteasomal degradation

    Neural stem cell

    Neural_stem_cell

  • List of human protein-coding genes 4
  • A0A1W2PQU2 7939 KARS1 HGNC:6215; Q15046 7940 KASH5 HGNC:26520; Q8N6L0 7941 KAT2A HGNC:4201; Q92830 7942 KAT2B HGNC:8638; Q92831 7943 KAT5 HGNC:5275; Q92993

    List of human protein-coding genes 4

    List_of_human_protein-coding_genes_4

  • DNA damage-inducible transcript 3
  • Human protein and coding gene

    PMID 29391905. Li T, Su L, Lei Y, Liu X, Zhang Y, Liu X (April 2015). "DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum

    DNA damage-inducible transcript 3

    DNA damage-inducible transcript 3

    DNA_damage-inducible_transcript_3

  • Histone acetyltransferase
  • Enzymes that catalyze acyl group transfer from acetyl-CoA to histones

    Yin Z, Liu R, Xia Y, Tan L, Yang P, Lee J, et al. (December 6, 2017). "KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase"

    Histone acetyltransferase

    Histone acetyltransferase

    Histone_acetyltransferase

  • H4K91ac
  • Histone acetylation on tail of histone H4

    start site (TSS) of active and poised genes. Histone acetyltransferase KAT2A is the specific reader. Proteins are typically acetylated on lysine residues

    H4K91ac

    H4K91ac

  • Cancer Genome Project
  • pharmacological inhibition on select genes. Inhibition of one of the selected genes, KAT2A, was able to suppress the growth of the AML cells across several genotypes

    Cancer Genome Project

    Cancer_Genome_Project

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Online names & meanings

  • Aliza
  • Girl/Female

    Indian

    Aliza

    Joy, Joyous (The daughter of Ali ra)

  • Paulino
  • Boy/Male

    French, German, Portuguese

    Paulino

    Intelligent One; Small

  • Kasirah
  • Girl/Female

    Arabic, Muslim

    Kasirah

    Plenty

  • Kasturiranga
  • Boy/Male

    Hindu, Indian

    Kasturiranga

    Lord Ranganath

  • Seed
  • Surname or Lastname

    English (chiefly Lancashire)

    Seed

    English (chiefly Lancashire) : from Middle English sede ‘seed’; a metonymic occupational name for a gardener or husbandman, or a nickname for a small person.English (chiefly Lancashire) : from a late Old English personal name, Sida, a post-Conquest short form of compound names formed with sidu ‘custom’, ‘manner’; ‘morality’, ‘purity’ as the first element.

  • JESSE
  • Male

    English

    JESSE

    Anglicized form of Hebrew Yishay, JESSE means "I possess" or "wealthy." In the bible, this is the name of the father of King David.

  • JULIJA
  • Female

    Slovene

    JULIJA

     Feminine form of Slovene Júlij, JULIJA means "descended from Jupiter (Jove)." Compare with other forms of Julija.

  • Pranab | ப்ரணப 
  • Boy/Male

    Tamil

    Pranab | ப்ரணப 

    Lord Vishnu

  • Morsal
  • Girl/Female

    Afghan, Australian

    Morsal

    Flower

  • Oojam | ஊஜம
  • Boy/Male

    Tamil

    Oojam | ஊஜம

    Enthusiasm

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