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Chemical compound
Macitentan, sold under the brand name Opsumit, is an endothelin receptor antagonist developed by Actelion and approved for the treatment of pulmonary arterial
Macitentan
Medication
Macitentan/tadalafil, sold under the brand name Opsynvi, is a fixed dose combination medication used for the treatment of pulmonary arterial hypertension
Macitentan/tadalafil
Increased blood pressure in lung arteries
include epoprostenol, treprostinil, iloprost, bosentan, ambrisentan, macitentan, and sildenafil, tadalafil, selexipag, riociguat. Lung transplantation
Pulmonary_hypertension
American multinational pharmaceutical and medical device company
a nasal spray for depression (1.8% of revenues); OPSUMIT (macitentan)/OPSYNVI (macitentan/tadalafil) for pulmonary arterial hypertension (2.5% of revenues);
Johnson_&_Johnson
Medication used to treat erectile dysfunction
doi:10.1177/1756287214531639. PMC 4054509. PMID 25083163. "Ppsynvi (macitentan and tadalafil) Becomes the First and Only Health Canada-Approved Once
Tadalafil
Drug that blocks endothelin receptors
dual receptor endothelin receptor antagonist. aprocitentan, bosentan, macitentan, tezosentan, Feloprentan (LU-302872 the HCl salt is called LU-420627)
Endothelin receptor antagonist
Endothelin_receptor_antagonist
Pharmaceutical drug classification
C02KX03 Sitaxentan C02KX04 Macitentan C02KX05 Riociguat C02KX06 Sotatercept C02KX52 Ambrisentan and tadalafil C02KX54 Macitentan and tadalafil C02LA01 Reserpine
ATC_code_C02
Cell surface receptors
BQ-788 Clazosentan Darusentan Edonentan Enrasentan Fandosentan Feloprentan Macitentan Nebentan Sitaxentan Sparsentan Tezosentan Zibotentan Agonists Galanin
Signaling_peptide_receptor
Swiss biopharmaceutical company
for the PAH (Pulmonary Arterial Hypertension) market include: Opsumit (Macitentan): Actelion received approval from the FDA for the manufacture of this
Actelion
Medical condition of the eye
in Pennsylvania found that a potential side effect of medications like macitentan, an endothelin receptor antagonist that is used to treat pulmonary arterial
Cotton_wool_spots
Medical condition
Other drug trials are ongoing in patients with inoperable CTEPH, with macitentan recently proving efficacy and safety in MERIT Pulmonary endarterectomy
Chronic thromboembolic pulmonary hypertension
Chronic_thromboembolic_pulmonary_hypertension
Vasoconstricting peptide family
potentially lethal effects in the liver. Bosentan was a precursor to macitentan, which was approved in 2013. Davenport AP, Hyndman KA, Dhaun N, Southan
Endothelin
M-Predrol M-Zole M.V.C. 9+3 M.V.I. mabuprofen (INN) mabuterol (INN) Maci macitentan (INN) Macrobid Macrodantin macrosalb (131 I) (INN) macrosalb (99m tc)
List_of_drugs:_M–Md
BQ-788 Clazosentan Darusentan Edonentan Enrasentan Fandosentan Feloprentan Macitentan Nebentan Sitaxentan Sparsentan Tezosentan Zibotentan Agonists: Galanin
List of signaling peptide/protein receptor modulators
List_of_signaling_peptide/protein_receptor_modulators
MACITENTAN
MACITENTAN
MACITENTAN
MACITENTAN
Girl/Female
Assamese, Gujarati, Hindu, Indian, Kannada, Marathi, Sindhi, Tamil, Telugu
Pure; Like a Pearl
Boy/Male
Hindu
Happy
Girl/Female
Christian, Hindu, Indian
Gem; Cloud
Surname or Lastname
English
English : from the Old English personal name BÄ“da, of which the most famous bearer was the Venerable Bede, the 8th century theologian and historian. Use of the personal name, though rare, continued long enough into the medieval period to give rise to the surname.
Girl/Female
Hindu, Indian, Tamil
Wisdom; Goddess Saraswati
Girl/Female
Hindu
Sweet person, Sweet, Surgery
Surname or Lastname
English
English : variant of Shadrick.
Boy/Male
Tamil
Name of one of the Pandavas
Girl/Female
Hindu, Indian
Wealthy
Boy/Male
Indian, Punjabi, Sikh
Wise; Intelligent
MACITENTAN
MACITENTAN
MACITENTAN
MACITENTAN
MACITENTAN