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MED1

  • MED1
  • Protein-coding gene in the species Homo sapiens

    Mediator complex and is a protein that in humans is encoded by the MED1 gene. MED1 functions as a nuclear receptor coactivator. The activation of gene

    MED1

    MED1

    MED1

  • Mediator (coactivator)
  • Multiprotein complex involved in transcription in eukaryotes

    many proteins. MED1 is targeted by miR-1, which is important in gene regulation in cancers. The tumor suppressor miR-137 also regulates MED1. Null mutants

    Mediator (coactivator)

    Mediator (coactivator)

    Mediator_(coactivator)

  • BioPlex
  • The interaction network of MED1, one of the subunit of the Mediator complex.

    BioPlex

    BioPlex

    BioPlex

  • MBD4
  • Protein-coding gene in the species Homo sapiens

    Cicchillitti L, Schepis F, Riccio A, Yeung AT, Matsumoto Y, et al. (May 1999). "MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch

    MBD4

    MBD4

    MBD4

  • PGC-1α
  • Protein-coding gene in the species Homo sapiens

    (ERR-β), estrogen-related receptor gamma (ERR-γ). Farnesoid X receptor FBXW7 MED1, MED12, MED14, MED17, NRF1 Peroxisome proliferator-activated receptor gamma

    PGC-1α

    PGC-1α

    PGC-1α

  • Androgen receptor
  • Mammalian protein found in humans

    FOXO1, GAPDH, Gelsolin, GNB2L1, GSK3B, HDAC1, HSP90AA1, HTATIP, MAGEA11, MED1, MYST2, NCOA1, NCOA2, NCOA3, NCOA4, NCOA6, NCOR2, NONO, p300, PA2G4, PAK6

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • P53
  • Mammalian protein found in humans

    HMGB1, HSPA9, Huntingtin, ING1, ING4, ING5, IκBα, KPNB1, LMO3, Mdm2, MDM4, MED1, MAPK9, MNAT1, NDN, NCL, NUMB, NF-κB, P16, PARC, PARP1, PIAS1, CDC14B, PIN1

    P53

    P53

    P53

  • Sulodexide
  • Pharmaceutical drug

    Research Reviews. 18 (1): 1–20. doi:10.1002/(SICI)1098-1128(199801)18:1<1::AID-MED1>3.0.CO;2-4. PMID 9436179. S2CID 26366651. Lauver DA, Booth EA, White AJ,

    Sulodexide

    Sulodexide

  • Chromosome 17
  • Human chromosome

    protein kinase kinases: MAP2K3, MAP2K4, MAP2K6 Mediator complex subunits: MED1, MED9, MED11, MED13, MED24, MED31 Myosins: MYH1, MYH2, MYH3, MYH4, MYH8,

    Chromosome 17

    Chromosome 17

    Chromosome_17

  • Mariam Coulibaly (television presenter)
  • Ivorian journalist (born 1977)

    Retrieved 2024-05-20. "Mariam Coulibaly, une animatrice radio de renom". Med1 TV (in French). 2024-03-08. Retrieved 2024-05-20. Mercereau, Damien (2013-12-16)

    Mariam Coulibaly (television presenter)

    Mariam Coulibaly (television presenter)

    Mariam_Coulibaly_(television_presenter)

  • Natural product
  • Chemical compound or substance produced by a living organism, found in nature

    Research Reviews. 20 (1): 1–27. doi:10.1002/(SICI)1098-1128(200001)20:1<1::AID-MED1>3.0.CO;2-A. PMID 10608919. S2CID 25117225. Petek BJ, Loggers ET, Pollack

    Natural product

    Natural product

    Natural_product

  • ARGLU1
  • Protein-coding gene in the species Homo sapiens

    located at 13q33.3. The protein product of this gene has been proposed as a MED1-interacting protein required for estrogen-dependent gene transcription and

    ARGLU1

    ARGLU1

    ARGLU1

  • Sensenbrenner syndrome
  • Medical condition

    transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4". Dev. Biol. 325 (1): 225–37. doi:10.1016/j.ydbio.2008.10.020. PMC 2645042

    Sensenbrenner syndrome

    Sensenbrenner syndrome

    Sensenbrenner_syndrome

  • Glucocorticoid receptor
  • Receptor to which cortisol and other glucocorticoids bind

    shown to interact with: BAG1, CEBPB, CREBBP, DAP3, DAXX, HSP90AA1, HNRPU, MED1, MED14, Mineralocorticoid receptor, NRIP1, NCOR1, NCOA1, NCOA2, NCOA3, POU2F1

    Glucocorticoid receptor

    Glucocorticoid receptor

    Glucocorticoid_receptor

  • Trabectedin
  • Chemical compound

    Research Reviews. 20 (1): 1–27. doi:10.1002/(SICI)1098-1128(200001)20:1<1::AID-MED1>3.0.CO;2-A. PMID 10608919. S2CID 25117225. Cromie WJ (4 May 2000). "Potent

    Trabectedin

    Trabectedin

    Trabectedin

  • Emergency medical services in Sri Lanka
  • former team members founded Med1 (Pvt) Ltd. in 2011 to provide commercial prehospital care in Colombo and suburbs. Med1 secured the short code 1-9-9-0

    Emergency medical services in Sri Lanka

    Emergency_medical_services_in_Sri_Lanka

  • Hepatocyte nuclear factor 4 alpha
  • Protein-coding gene in the species Homo sapiens

    alpha has been shown to interact with: Beta-catenin, CREB binding protein, MED1, MED14, Small heterodimer partner Testicular receptor 4, Hepatocyte nuclear

    Hepatocyte nuclear factor 4 alpha

    Hepatocyte nuclear factor 4 alpha

    Hepatocyte_nuclear_factor_4_alpha

  • Chemical space
  • Concept in cheminformatics

    Research Reviews. 16 (1): 3–50. doi:10.1002/(SICI)1098-1128(199601)16:1<3::AID-MED1>3.0.CO;2-6. PMID 8788213. S2CID 44271689. Kirkpatrick, P.; C. Ellis (2004)

    Chemical space

    Chemical space

    Chemical_space

  • Base excision repair
  • DNA repair process

    Arnoletti JP (Jan 2009). "Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer". Cancer Biology & Therapy. 8 (1):

    Base excision repair

    Base excision repair

    Base_excision_repair

  • Haplogroup M30 (mtDNA)
  • Human mitochondrial DNA haplogroup

    I6945 R64 Roopkund Lake, India 687-870 CE Harney, É. et al. M30-C16234T — Med1 Kashmir valley, India 1444-1617 CE Dwivedi, A. et al. M30c I3346 R15 Roopkund

    Haplogroup M30 (mtDNA)

    Haplogroup_M30_(mtDNA)

  • The Cancer Genome Atlas
  • Project to catalogue genetic mutations responsible for cancer

    CD274 and PDCD1LG2 immune checkpoint genes; alterations to genes including MED1, ERBB3, CASP8, HLA-A, and TGFBR2 and fusions involving lncRNA BCAR4; nearly

    The Cancer Genome Atlas

    The_Cancer_Genome_Atlas

  • MiR-205
  • Micro RNA involved in the regulation of multiple genes

    specific target in the 3'-UTR sequence of MED1, which plays an important role in placental development, and silences MED1 expression in human trophoblasts exposed

    MiR-205

    MiR-205

    MiR-205

  • Estrogen receptor alpha
  • Protein-coding gene in the species Homo sapiens

    DNTTIP2 EP300 ESR2 FOXO1 GREB1 GTF2H1 HSPA1A HSPA8 HSP90AA1 ISL1 JARID1A MVP MED1 MED12 MED14 MED16 MED24 MED6 MGMT MNAT1 MTA1 NCOA6 NCOA1 NCOA2 NCOA3 NRIP1

    Estrogen receptor alpha

    Estrogen receptor alpha

    Estrogen_receptor_alpha

  • D3web
  • Germany) going back to the 1980s, starting with the medical expert systems MED1 and MED2 . Whereas the original systems were focussed on medical diagnosis

    D3web

    D3web

  • MED25
  • Protein-coding gene in the species Homo sapiens

    Krutchinsky A, Fukuda A, Chen W, Yamamura S, Chait BT, Roeder RG (Jul 2005). "MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in

    MED25

    MED25

    MED25

  • DNA glycosylase
  • Enzymes involved in base excision repair

    Arnoletti JP (Jan 2009). "Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer". Cancer Biology & Therapy. 8 (1):

    DNA glycosylase

    DNA_glycosylase

  • Topoisomerase inhibitor
  • Compounds that inhibit the activity of DNA topoisomerases

    Research Reviews. 20 (4): 231–293. doi:10.1002/1098-1128(200007)20:4<231::AID-MED1>3.0.CO;2-N. ISSN 1098-1128. PMID 10861727. S2CID 24531327. Laponogov I, Sohi

    Topoisomerase inhibitor

    Topoisomerase_inhibitor

  • MED13
  • Protein-coding gene in the species Homo sapiens

    Krutchinsky A, Fukuda A, Chen W, Yamamura S, Chait BT, Roeder RG (Jul 2005). "MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in

    MED13

    MED13

    MED13

  • 2017–18 Botola Pro
  • Moroccan football league season

    Joly3 IR Tanger Driss El Mrabet Bang Sports Renault, APM Terminals, Tanger-Med1, Moroccan Airports Authority1, Valencia1, RCI Finance Maroc3 Kawkab Marrakesh

    2017–18 Botola Pro

    2017–18_Botola_Pro

  • MLH1
  • Protein-coding gene in humans

    A, Yeung AT, Matsumoto Y, Golemis EA, Genuardi M, Neri G (March 1999). "MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch

    MLH1

    MLH1

    MLH1

  • LRPPRC
  • Protein-coding gene in the species Homo sapiens

    PMID 14743216. S2CID 11683986. Labialle S, Dayan G, Gayet L, et al. (2004). "New invMED1 element cis-activates human multidrug-related MDR1 and MVP genes, involving

    LRPPRC

    LRPPRC

    LRPPRC

  • Thyroid hormone receptor alpha
  • Protein-coding gene in the species Homo sapiens

    hypothyroidism. THR1 has been shown to interact with: COPS2, EP300, ITGB3BP, MED1, MED6, MED12, MED16, MEF2A, NCOA6, TRIP11, and UBC. GRCh38: Ensembl release

    Thyroid hormone receptor alpha

    Thyroid hormone receptor alpha

    Thyroid_hormone_receptor_alpha

  • Virtual screening
  • Computational technique of discovering new drugs

    Res. Rev. 16 (1): 3–50. doi:10.1002/(SICI)1098-1128(199601)16:1<3::AID-MED1>3.0.CO;2-6. PMID 8788213. McGregor MJ, Luo Z, Jiang X (June 11, 2007). "Chapter

    Virtual screening

    Virtual screening

    Virtual_screening

  • Cyclin-dependent kinase 8
  • Protein-coding gene in the species Homo sapiens

    kinase 8 has been shown to interact with: CCNC CREB binding protein CRSP3 MED1 MED12 MED14 MED16 MED17 MED21 MED24 MED26 MED6 Notch proteins POLR2A SMARCB1

    Cyclin-dependent kinase 8

    Cyclin-dependent kinase 8

    Cyclin-dependent_kinase_8

  • MED26
  • Protein-coding gene in the species Homo sapiens

    Krutchinsky A, Fukuda A, Chen W, Yamamura S, Chait BT, Roeder RG (July 2005). "MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in

    MED26

    MED26

    MED26

  • Mir-491 microRNA precursor family
  • RNA family

    Chu T, Nelson DM, Mishima T, Sadovsky Y (June 2010). "MiR-205 silences MED1 in hypoxic primary human trophoblasts". FASEB Journal. 24 (6): 2030–9. doi:10

    Mir-491 microRNA precursor family

    Mir-491_microRNA_precursor_family

  • List of human protein-coding genes 5
  • HGNC:3498; Q03112 9403 MECP2 HGNC:6990; P51608 9404 MECR HGNC:19691; Q9BV79 9405 MED1 HGNC:9234; Q15648 9406 MED4 HGNC:17903; Q9NPJ6 9407 MED6 HGNC:19970; O75586

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

  • TGS1
  • Protein-coding gene in the species Homo sapiens

    TGS1 has been shown to interact with: CREB-binding protein, and EED, EP300, MED1, and NCOA6. GRCh38: Ensembl release 89: ENSG00000137574 – Ensembl, May 2017

    TGS1

    TGS1

    TGS1

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MED1

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MED1

Online names & meanings

  • STORMIE
  • Female

    English

    STORMIE

    Variant spelling of English Stormy, STORMIE means "stormy." 

  • Chandar
  • Boy/Male

    Hindu, Indian, Kannada, Marathi, Tamil, Telugu

    Chandar

    Moon

  • MARGARETA
  • Female

    Danish

    MARGARETA

    , pearl.

  • Claybrook
  • Surname or Lastname

    English

    Claybrook

    English : habitational name from any of various minor places named Claybrook, from Old English clǣg ‘clay’ + brōc ‘brook’, for example Claybrook in Shropshire or Claybrooke Magna and Claybrooke Parva in Leicestershire.

  • Hareendra
  • Boy/Male

    Hindu

    Hareendra

    Lord Shiva, A tree

  • HAANI
  • Female

    Chamoru

    HAANI

    , day.

  • Ethelda
  • Girl/Female

    Teutonic

    Ethelda

    Wise advisor.

  • Arppitha
  • Girl/Female

    Hindu, Indian

    Arppitha

    Render

  • Al-Karim
  • Boy/Male

    Indian

    Al-Karim

    The bountiful, The generous

  • Emmalyn
  • Girl/Female

    French German

    Emmalyn

    Hardworking.

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MED1

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