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Protein-coding gene in the species Homo sapiens
metalloproteinase-14 is an enzyme that in humans is encoded by the MMP14 gene. Matrix metalloproteinase-14 (MMP14), also known as MT1-MMP, is a zinc-dependent type I
MMP14
DNA pattern affecting anatomy development
respectively. HoxA3 induces endothelial cell (EC) migration by upregulating MMP14 and uPAR. Conversely, HoxD10 and HoxA5 have the opposite effect of suppressing
Homeobox
Family of zinc-dependent metalloendopeptidases
MMP-13 secreted Substrates include Col I, II, III, IV, IX, X, XIV, gelatin MMP14 MT1-MMP MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS
Matrix_metalloproteinase
Mammalian protein found in humans
(CCND1) Fibroblast growth factor 18 (FGF18) Matrix metalloproteinase-14 (MMP14) Myc proto-oncogene (MYC) Many of the genes activated by the β-catenin pathway
Catenin_beta-1
Protein family
metalloproteinases: MMP1, MMP2, MMP3, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17, MMP19, MMP20, MMP21, MMP24, MMP25, MMP27, MMP28, PRG4
Hemopexin_family
Protein-coding gene in humans
requires proteolytic processing. A complex of membrane type 1 MMP (MT1-MMP/MMP14) and tissue inhibitor of metalloproteinase 2 recruits pro-MMP 2 from the
MMP2
Biological pathway implicated in tumorigenesis
Calnexin is logically a promising targetable tumour antigen. In addition, MMP14 is another GalNAc-T substrate for which GALA induced glycosylation changes
GalNAc-T_activation_pathway
Protein-coding gene in the species Homo sapiens
human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in
MMP15
Protein-coding gene in the species Homo sapiens
and dendritic spines plasticity. TIMP2 has been shown to interact with: MMP14 and MMP2. TIMP1, TIMP3, TIMP4 GRCh38: Ensembl release 89: ENSG00000035862
TIMP2
Protein-coding gene in the species Homo sapiens
induce smooth muscle cell migration in response to PDGFB by activating MMP14. When Pcsk6 was knocked out, the intimal hyperplasia response to in vivo
PCSK6
Protein-coding gene in the species Homo sapiens
"Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively"
MMP16
A kind of tumor
MEN1 mutations are occasionally found in pediatric ependymomas. MMP2 and MMP14 appear to also play a role in tumor growth and progression in intracranial
Pediatric_ependymoma
Rare hereditary connective tissue disease
ajhg.2012.07.022. PMC 3512002. PMID 22922033. Reference, Genetics Home. "MMP14 gene". Genetics Home Reference. Retrieved 2017-11-07. "Winchester Syndrome
Winchester_syndrome
HGNC:7157; P24347 9657 MMP12 HGNC:7158; P39900 9658 MMP13 HGNC:7159; P45452 9659 MMP14 HGNC:7160; P50281 9660 MMP15 HGNC:7161; P51511 9661 MMP16 HGNC:7162; P51512
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
As lumican can directly bind to and inhibit matrix metalloproteinase-14 (MMP14), lumican may limit tumor progression by preventing extracellular matrix
Lumican
Protein-coding gene in the species Homo sapiens
Invasion is accompanied by proteolysis of the ECM through activation of MMP14, MMP2 and MMP9 metalloproteinases. NEDD9 is involved in chemokine-induced
NEDD9
Class of protein structural domains
domain include: MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17, MMP19, MMP20, MMP21, MMP24, MMP25, MMP27, MMP28 PDB:
Peptidoglycan_binding_domain
MMP14
MMP14
MMP14
MMP14
Girl/Female
Arthurian Legend
Grandmotber of Percival.
Girl/Female
Hindu, Indian
Auspicious; Goddess Lakshmi
Girl/Female
Arabic, French
Pleased; Happy
Male
Arthurian
, a king; first owner of Galahad's shield.
Surname or Lastname
English
English : nickname for a wealthy man (see Rich).English : occupational name for the servant of a man called Rich.English : variant of Richmond.German (Richmann) : from a Germanic personal name composed of the elements rīc ‘power(ful)’ + man ‘man’.German (Richmann) : nickname for a rich man.
Girl/Female
Arabic, Muslim
Sage; Philosopher; Physician; Doctor
Girl/Female
American, Bengali, Hindu, Indian, Sanskrit
Name of a River; Container of Glory
Boy/Male
Christian, Gaelic, Hindu, Indian, Irish, Punjabi, Sikh
Dusky; Dark-haired; Dark
Girl/Female
Indian, Tamil
Goddess Amman
Biblical
circumcised lamb; harvest; full of ears of corn
MMP14
MMP14
MMP14
MMP14
MMP14