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Protein-coding gene in the species Homo sapiens
Nuclear respiratory factor 1, also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcription factor
NRF1
Protein-coding gene in the species Homo sapiens
Nuclear factor erythroid 2-related factor 1 (Nrf1) also known as nuclear factor erythroid-2-like 1 (NFE2L1) is a protein that in humans is encoded by the
NFE2L1
Pharmaceutical compound
ASC-JM17, JM17, ALZ-003) is an agonist of nuclear respiratory factor 1 (NRF1), a nonsteroidal antiandrogen, and an androgen receptor degrader related
Rosolutamide
Class of proteins
degeneration. Similar results have also been observed in Nrf1 central nervous-specific knockout mice. The Nrf1-sMaf heterodimers regulate genes responsible for
Small_Maf
Human protein and coding gene
1006/bbrc.1997.6943. PMID 9240432. Venugopal R, Jaiswal AK (December 1996). "Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant
NFE2L2
Protein-coding gene in the species Homo sapiens
thought to downregulate PGC-1α, but upregulate its downstream effectors, NRF1 and NRF2. Akt itself is activated by PIP3, often upregulated by PI3K after
PGC-1α
Protein-coding gene in the species Homo sapiens
interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1
PPRC1
Topics referred to by the same term
magazine nrf, the ISO 639-3 code for Jèrriais and Guernésiais languages NRF1, Nuclear Respiratory Factor This disambiguation page lists articles associated
NRF
Protein-coding gene in the species Homo sapiens
transcription factors, such as CNC (cap 'n' collar) proteins [p45 NF-E2 (NFE2), Nrf1 (NFE2L1), Nrf2 (NFE2L2), and Nrf3 (NFE2L3)] and Bach proteins (BACH1 and
MAFG
Protein-coding gene in the species Homo sapiens
G, Juget M, Roussis V, Roussakis C (2002). "Effect of four genes (ALDH1, NRF1, JAM and KBL) on proliferation arrest in a non-small cell bronchopulmonary
GCAT
Protein-coding gene in humans
respiratory factor 1 (NRF1), cAMP response element-binding protein (CREB), PAR bZIP family and Sp4 transcription factor. NRF1 encodes a protein which
CCDC47
American geneticist
In a 2017 paper, Hotamisligil lab has identified a transcription factor, NRF1, that both senses and responds to excess cholesterol in the ER and acts together
Gökhan_S._Hotamisligil
Protein-coding gene in the species Homo sapiens
transcription factors, such as CNC (cap 'n' collar) proteins [p45 NF-E2 (NFE2), Nrf1 (NFE2L1), Nrf2 (NFE2L2), and Nrf3 (NFE2L3)] and Bach proteins (BACH1 and
MAFK
Nuclear receptor Known motif – High-throughput in vitro [655] SAAGKTCAAGKKYR NRF1 ENSG00000106459 Unknown Known motif – High-throughput in vitro [656] YRCGCATGCGC
List of human transcription factors
List_of_human_transcription_factors
Class of reduction–oxidation proteins
upregulates the transcriptional activity of nuclear respiratory factors 1 and 2 (NRF1 and NRF2) and stimulates the expression of peroxisome proliferator-activated
Thioredoxin
French biochemist and endocrinologist (1926–2025)
inhibits endometrial cancer cell progress through regulating miR-492/Klf5/Nrf1 axis". Cancer Cell International. 21 (1): 29. doi:10.1186/s12935-020-01682-1
Étienne-Émile_Baulieu
Mammalian protein found in Homo sapiens
PMID 8380166. Venugopal R, Jaiswal AK (December 1998). "Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated
Protein_c-Fos
Protein-coding gene in the species Homo sapiens
transcript to include 243 bp of mRNA transcript. Nuclear respiratory factor 1 (NRF1) is a transcription factor that had seven sites predicted to bind on the
FAM98A
Protein-coding gene in the species Homo sapiens
Satoh J, Kawana N, Yamamoto Y (2013). "Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis
C14orf80
Process by which cells build mitochondrial mass
(NRF2/GABPA), and together with NRF-2 coactivates nuclear respiratory factor 1 (NRF1). The NRFs, in turn, activate the mitochondrial transcription factor A (tfam)
Mitochondrial_biogenesis
Mammalian protein found in Homo sapiens
PMID 8380166. Venugopal R, Jaiswal AK (December 1998). "Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated
Transcription_factor_Jun
Pharmaceutical compound
carcinoma progression by blocking mitochondrial function through the PGC-1α/NRF1/TFAM signaling pathway". Frontiers in Oncology. 12 1055126. doi:10.3389/fonc
Agrimol_B
Protein-coding gene in the species Homo sapiens
expression is regulated by factors that include E2F cell cycle regulators, NRF1, and ZF5, and brachyury. Expression data from human, mouse, and developing
IRX1
Protein-coding gene in the species Homo sapiens
CREB cAMP-responsive element binding proteins NRF1 nuclear respiratory factor 1 CCAAT-enhancer-binding proteins factor KRAB domain zinc finger protein
DEPDC1B
Protein-coding gene in the species Homo sapiens
PMC 4684645. PMID 21057541. Venugopal R, Jaiswal AK (December 1998). "Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated
NFE2L3
American college basketball tournament
Championship Game April 9 OKC5 Louisville 64 SPK2 California 57 OKC5 Louisville 60 BRP1 Connecticut 93 NRF1 Notre Dame 65 BRP1 Connecticut 83
2013 NCAA Division I women's basketball tournament
2013_NCAA_Division_I_women's_basketball_tournament
Protein found in humans
with: NR3C4, BRCA1, CCNDBP1, CDK4, CDK6, ESR1, HDAC3, HDACs, NEUROD1, NCOA1, NRF1, p300, PACSIN2, PCNA, PPARG, RAD51, RB1, TAF1, and NR1A2. Parathyroid adenoma
Cyclin_D1
Mammalian protein found in Homo sapiens
absorption of folates. The PCFT minimal promoter has been defined and contains an NRF1 response element. There is also evidence for a role of vitamin D in the regulation
Proton-coupled folate transporter
Proton-coupled_folate_transporter
German molecular biology researcher (born 1969)
between DNA methylation and transcription factors determines binding of NRF1. Nature 528:575-9 Barisic D, Stadler MB, Iurlaro M, Schübeler D (2019) Mammalian
Dirk_Schübeler
Wei; Li, Chao; Zhang, Zhengwen; Taniguchi, Hiroaki; Ao, Ping (2025-07-07). "Nrf1 acts as a highly-conserved determinon for maintaining robust redox homeostasis
Murburn_concept
Protein-coding gene in the species Homo sapiens
for transcription factors such as GATA binding factors, SMAD3, TP63 and NRF1. MIPOL1 is ubiquitously expressed at low levels in humans, with highest expression
MIPOL1
Protein-coding gene in the species Homo sapiens
1074/jbc.272.51.32163. PMID 9405416. Venugopal R, Jaiswal AK (1999). "Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated
JUNB
Protein-coding gene
transcription factors, such as CNC (cap 'n' collar) proteins [p45 NF-E2 (NFE2), Nrf1 (NFE2L1), Nrf2 (NFE2L2), and Nrf3 (NFE2L3)] and Bach proteins (BACH1 and
MAFF_(gene)
Medical condition
regulation have been described and include the minimal promoter, Vitamin D and NRF1 response elements. PCFT operates most efficiently when there is a strong
Hereditary folate malabsorption
Hereditary_folate_malabsorption
Protein-coding gene in the species Homo sapiens
elements related to the cell cycle and neuronal development and includes AP-2, NRF1, BRAC, E2F, NEUR, and NRSF. The second consists of elements related to brain
LCHN
Protein-coding gene in the species Homo sapiens
PMID 9739985. S2CID 44836385. Venugopal R, Jaiswal AK (1998). "Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated
JunD
Protein-coding gene in humans
co-immunoprecipitation (Co-IP) experiments revealed interacting protein NRF1 nuclear respiratory factor 1 This gene encodes a protein that homodimerizes
CFAP206
Protein-coding gene in the species Homo sapiens
affinity sites 423 441 (-) 1.00 TCF11 transcription factor TCF11/LCR-F1/Nrf1 homodimers 559 565 (+) 1.00 EVI1-myleoid transforming protein MEL1 (MDS1/EVI1-like
FAM110A
Protein-coding gene in humans
been shown to interact with: BCL2L11, DLG4 DLGAP1, DYNC1I1, IκBα, MYO5A, NRF1, PAK1, and TP53BP1. GRCh38: Ensembl release 89: ENSG00000088986 – Ensembl
DYNLL1
Protein
LIG4-CCDC176 interaction. The second and third predicted interactions are NRF1 and HYLS1. The predicted secondary structure of BBOF1 in humans is as follows:
CCDC176
Protein-coding gene in the species Homo sapiens
Detailed Family Information V$ZF15 C2H2 zinc finger transcription factors 15 V$NRF1 Nuclear respiratory factor 1 V$MYBL Cellular and viral myb-like transcriptional
C6orf136
Protein-coding gene in the species Homo sapiens
humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1". Proc. Natl. Acad. Sci. U.S.A. 100 (14): 8466–71. Bibcode:2003PNAS..100
PPARGC1B
Protein-coding gene in the species Homo sapiens
predicted to bind to conserved sites on the promoter region (GXP_7545710) are NRF1, E2F, ZF5, and AHR. The human C5orf24 gene has three mRNA transcript variants
C5orf24
Mammalian protein found in Homo sapiens
v t e Regulome Activates Runx2, nrf1, Bip Inhibits ATF4, CHOP Is activated by not, PERK
ATF4
Human protein
systems, as well as intrauterine development. Transcription factors TFIIB and NRF1 both occur twice within the first 100 base pairs upstream from the transcription
CXorf38_Isoform_1
Protein
Factors. Transcription factor Description Matrix similarity TCF11 TCF11/LCR-F1/Nrf1 homodimers 1 TFIIB Transcription factor II B (TFIIB) recognition element
TMEM39B
Gene profile for C10orf88 (aka PAAT)
contexts, consistent with the gene's expression profile. Key factors include NRF1, NR2C2, ELK4, ETV4, TFAP2A, and IRF3. PAAT functions as a novel ATPase, catalyzing
PAAT_(protein)
O43847 10802 NRDE2 HGNC:20186; Q9H7Z3 10803 NREP HGNC:16834; Q16612 10804 NRF1 HGNC:7996; Q16656 10805 NRG1 HGNC:7997; Q02297 10806 NRG2 HGNC:7998; O14511
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
Protein-coding gene in the species Homo sapiens
transcription factor Nanog V$TCFF TCF11 transcription factor V$TCF11.01 TCF11/LCR-F1/Nrf1 homodimers V$PERO Peroxisome proliferator-activated receptor V$PPAR_RXR.01
FAM214B
Protein-coding gene in the species Homo sapiens
round of initiation. Both eIF2α and eIF2β expression is regulated by the NRF1 transcription factor. eIF2 GRCh38: Ensembl release 89: ENSG00000125977 –
EIF2S2
Protein-coding gene in the species Homo sapiens
complex 0.834 P53F Tumor suppressor p53 (3' half site) 0.921 TCFF TCF11/LCP-F1/Nrf1 homodimers 1.000 FKHD Fork head homologous X binds DNA with a dual sequence
C9orf85
NRF1
NRF1
NRF1
NRF1
Boy/Male
Indian, Punjabi, Sikh
Modest Lamp
Boy/Male
Tamil
Snehin | ஸà¯à®¨à¯‡à®¹à®¿à®‚Â
A friend
Boy/Male
Indian
Desire, Wish
Female
Persian/Iranian
Variant spelling of Persian Nasrin, NASREEN means "wild rose."
Boy/Male
Arabic, Pakistani
Raat; Night
Girl/Female
German
Champion
Surname or Lastname
Dutch and German
Dutch and German : from a pet form of Nick, a short form of the personal name Nikolaus (see Nicholas).English : variant spelling of Nichol.
Girl/Female
Indian
Thankfulness, Praise
Boy/Male
Hindu
Victorious
Male
Russian
(Ðнтон) Russian form of Greek Antonios, possibly ANTON means "invaluable." Compare with other forms of Anton.
NRF1
NRF1
NRF1
NRF1
NRF1