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Miniaturized and simplified version of an organ
An organoid is a miniaturised and simplified version of an organ produced in vitro in three dimensions that mimics the key functional, structural, and
Organoid
Artificial miniature brain like organ
A cerebral organoid describes an artificially grown, in vitro, tissue resembling parts of the human brain. Cerebral organoids are created by culturing
Cerebral_organoid
Field of study in computer science and biology
Organoid intelligence (OI) is an emerging field of study in computer science and biology that develops and studies biological wetware computing using 3D
Organoid_intelligence
3D in vitro tissue culture system
term, neural organoids encompasses various models including cerebral organoids, spinal organoids, and retinal organoids. Neural organoid models are used
Neural_organoid
Television series
discovers a mysterious girl named Fiona (Fine in the Japanese version), and an Organoid named Zeke (Sieg). Van discovers that Zeke has the ability to merge with
Zoids:_Chaotic_Century
Biological model of 2 or more cell types
An assembloid is an in vitro model that combines two or more organoids, spheroids, or cultured cell types to recapitulate structural and functional properties
Assembloid
Medical condition
Latin name, the second term is its name in English; also known as an "organoid nevus" and "nevus sebaceus of Jadassohn") is a congenital, hairless plaque
Nevus_sebaceous
Method of growing stem cells
epithelium (basal stem cells) were isolated and used in developing 3D organoids that could be used for various studies, including tumor studies. The cell
Air–liquid interface cell culture
Air–liquid_interface_cell_culture
Austrian biomedical research organisation
cerebral organoids 2020: Discovery on the conformation of sister chromatids in the replicated human genome 2019: Generation of blood vessel organoids from
Institute of Molecular Biotechnology
Institute_of_Molecular_Biotechnology
Austrian molecular biologist
molecular biologist known mainly as a pioneer in developing cerebral organoids. Since 2005, he is a Senior Group Leader at the Institute of Molecular
Jürgen_Knoblich
Italian molecular biologist (born 1971)
the cerebral cortex. She is best known for her work using 3D cerebral organoids derived from human induced pluripotent stem cells (iPSCs) to study cortical
Paola_Arlotta
Stem cell-based embryo model
modelling. Simunovic, Mijo; Brivanlou, Ali H. (14 March 2017). "Embryoids, organoids and gastruloids: new approaches to understanding embryogenesis". Development
Blastoid_(embryoid)
Embryonic Stem Cells
they lack fore- mid- and hindbrain. They are a model system an embryonic organoid for the study of mammalian development (including humans) and disease.
Gastruloid
Culture of cells from fresh tissues
creation of three-dimensional (3D) organ-like architectures known as "organoids," which are able to exhibit properties of their corresponding real organs
Primary_cell_culture
Cultrex BME is commonly used for the culture of pluripotent stem cells and organoids.[citation needed] Cultrex BME is gelatinous at 4 °C. The matrix proteins
Cultrex_BME
Intelligence of machines
Hypothetical process of digitally emulating a brain Organoid intelligence – Use of brain cells and brain organoids for intelligent computing Outline of deep learning
Artificial_intelligence
American cancer biologist (born 1966)
pancreatic cancer and more recently, for his work developing pancreatic cancer organoids. David Tuveson received a B.S. in chemistry from the Massachusetts Institute
David_Tuveson
Test methods that avoid the use of animals
test new drugs. Organoids grow in vitro on scaffolds (biological or synthetic hydrogels such as Matrigel) or in a culture medium. Organoids are derived from
Alternatives to animal testing
Alternatives_to_animal_testing
Computer composed of organic material
self-repair at the cellular and network level. The development of cerebral organoids—miniature lab-grown brains—demonstrates spontaneous learning behavior
Wetware_computer
Collection of tissues with similar functions
Commons has media related to Organ systems. List of organs of the human body Organoid Organ-on-a-chip Situs inversus Widmaier, E P; Raff, H; Strang, KT (2014)
Organ_(biology)
When the human brain ceases to make new neurons and stops developing in humans
outcomes. Advances in magnetic resonance imaging and the study of brain organoids have enhanced understanding of neurological disorders and critical periods
Timeline of human brain development
Timeline_of_human_brain_development
cell-based assays, advanced 3D in vitro human-derived systems such as organoids or organs-on-a-chip, predictive in silico computational models such as
New_approach_methodologies
Line of stem cells for research
A myelinoid or myelin organoid is a three dimensional in vitro cultured model derived from human pluripotent stem cells (hPSCs) that represents various
Myelinoid
Unspecialized biological cell that can become specialized
various sources for stem cells. Research is attempting to generating organoids using stem cells, which would allow for further understanding of human
Stem_cell
Microfluidic bioengineered 3D-model
which better mimic physiological features than conventional 3D intestinal organoid culture. A variety of different intestine-on-a-chip models systems have
Intestine-on-a-chip
Scientists coalesce recent developments using human brain organoids into a new field they term organoid intelligence (OI), seeking to harness OI for computing
Timeline_of_biotechnology
Phase of embryonic development
ethical concerns, but can be done using organoids developed in vitro without the use of a human embryo. Organoids are simplified organ structures made from
Organogenesis
2024 book by Jonathan Birch
including people with disorders of consciousness, human fetuses, brain organoids, cephalopods, crustaceans, and artificial intelligence systems. He argues
The_Edge_of_Sentience
Romanian-American scientist
neuropsychiatric disease. Pașca's work has helped establish human neural organoids and assembloids as experimental platforms for studying human brain development
Sergiu_P._Pașca
Mathematical image techniques
Digital volume correlation analysis of micromechanical compression in a 3D organoid. The tracked nodes inform volumetric deformation, including cellular displacement
Digital image correlation and tracking
Digital_image_correlation_and_tracking
Australian biotechnology company
human brain. Biological computing Brain organoid Brain-computer interface Neuromorphic engineering Organoid intelligence Wetware computer "Australian
Cortical_Labs
American spaceflight and AI company
August 11, 2019. Thompson, Amy (December 5, 2020). "Tissue chips and organoids: SpaceX is launching lots of science to space for NASA on Sunday". Space
SpaceX
Swiss biomedical engineer
in vitro organoids mimicking healthy and diseased tissues and organs. Lütolf's laboratory has also pioneered designer matrices for organoid culture, including
Matthias_Lütolf
Family of Notch signalling genes
disorders, and they showed that loss of NOTCH2NL in cortical organoids leads to the organoids being smaller, while resulting in premature differentiation
NOTCH2NL
Topics referred to by the same term
Japanese cruiser Ōi O-I, a Japanese tank design of the Second World War Organoid intelligence, a field of study related to computer science and biology
Oi
Genetic disorder affecting mostly the lungs
functional repair in culture of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Bacteriophage therapy (phage therapy) is
Cystic_fibrosis
Australian scientist and academic (born 1963)
Institute produced the world’s first kidney in a dish. Known today as kidney organoids, this research has become a foundation of ongoing work to find a regenerative
Melissa_Little
Brazilian biologist
neuroscience of brain development, using human and "Neanderthalized" brain organoids developed from stem cells. He is one of the most scientifically impactful
Alysson_Muotri
Principles for ethical use of animals in science
known as organoids or mini-organs, have replaced animal models for some types of research. In recent years, scientists have produced organoids that can
Three_Rs_(animal_research)
University-affiliated research center
augmented reality-assisted medical care for emergency response and a brain organoid platform to study the effects of mild blast-induced traumatic brain injury
Johns Hopkins University Applied Physics Laboratory
Johns_Hopkins_University_Applied_Physics_Laboratory
American biotechnology company
capabilities. In 2019, the organoid platform was established, and Crown Bioscience entered into a strategic partnership with Hubrecht Organoid Technology (HUB)
Crown_Bioscience
All Latin and Greek roots beginning with G
microorganism, organ, organic, organism, organist, organize, organogenesis, organoid, organoleptic, orgiastic, orgy, parergon, surgeon, synergism, synergy,
List of Greek and Latin roots in English/A–G
List_of_Greek_and_Latin_roots_in_English/A–G
Embryologic stage in which germ layers form
Finally, using 3D embryoid body- and organoid-based techniques, small aggregates of mouse ESCs (Embryonic Organoids, or Gastruloids) are able to show a
Gastrulation
Gland between the intestinal villi that produces new cells
biology to further understand stem cell niches, and to generate intestinal organoids. The crypts of Lieberkühn are named after the eighteenth-century German
Intestinal_gland
Dutch molecular genetics and stem cell researcher
adult stem cells, creating organoids of the small intestine. Clevers's group has applied this technology to culturing organoids from other organs, such as
Hans_Clevers
American developmental biologist
cerebral organoids, or brain organoids, and used them to demonstrate the first disease model from induced pluripotent stem cell-derived organoids, an approach
Madeline_Lancaster
elucidated using this model system.[citation needed] Three dimensional organoid culture methods have become a popular way of recapitulating AD pathology
Experimental models of Alzheimer's disease
Experimental_models_of_Alzheimer's_disease
Phenomenon in which AI achievements are reclassified as non-intelligent
Computational intelligence Artificial intelligence in video games God of the gaps Organoid intelligence Haenlein, Michael; Kaplan, Andreas (2019). "A Brief History
AI_effect
Central organ of the human nervous system
behaviour, and the creation of neuronal maps. The development of cerebral organoids has opened ways for studying the growth of the brain, and of the cortex
Human_brain
Stem cell biologist
chronic liver disease and cancer. Her group have extensively developed human organoid models to study the molecular basis of adult tissue regeneration. Having
Meritxell_Huch
Species of virus
SEM image of influenza A virions infecting ciliated cells of human nasal epithelial organoid
Influenza_A_virus
Mouse carrying functioning human genes, cells, etc.
cerebral organoids transplanted into mice functionally integrate with their visual cortex. Such models may raise similar ethical issues as organoid-based
Humanized_mouse
Medical condition
a rare neurocutaneous condition characterized by the combination of an organoid sebaceous nevus and speckled lentiginous nevus. It is an unusual variant
Phakomatosis pigmentokeratotica
Phakomatosis_pigmentokeratotica
2673-7523 Optics 2020 2673-3269 Oral 2021 2673-6373 Organics 2020 2673-401X Organoids 2022 2674-1172 Osteology Medicine 2021 2673-4036 Oxygen 2021 2673-9801
List of MDPI academic journals
List_of_MDPI_academic_journals
The following is a partial list of the "A" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)
List_of_MeSH_codes_(A10)
Medical condition
substantially from human endometriosis. One alternative is the use of organoids, miniature organs derived from the cells of women with endometriosis,
Endometriosis
Generation and application of muscle tissue
left ventricle. Human Cardiac Organoids:an in vitro, scaffold-free technique for producing a functioning cardiac organoid; cardiac spheroids made from
Muscle_tissue_engineering
Hong Kong-born cell and developmental biologist
quickly. Li's lab have used a variety of models, including an innovative organoid system, to reveal a new way that a molecule called Wnt is activated in
Vivian_Li
Philosophical thought experiment
externalism Isolated brain Metaverse Mind uploading Neurally controlled animat Organoid intelligence Red pill Simulation hypothesis Skeptical hypothesis Solipsism
Brain_in_a_vat
First stage of pregnancy
endometrium that could more clearly identify causes of implantation failure. Organoids have also been developed to model the endometrium and its role in implantation
Implantation_(embryology)
American scientist
Singh is a pioneering researcher and inventor in the field of immune organoids, a discipline he has advanced and established as a significant area of
Ankur_Singh
Phenomenon of drug metabolism
"Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid". Cells. 10 (12): 3301. doi:10.3390/cells10123301. ISSN 2073-4409. PMC 8699265
First_pass_effect
Neural stem cell culture system
and more varied cell types arise with a longer time in culture. Cerebral organoid Neural stem cell Progenitor cell Adult stem cell Kempermann, Gerd. Adult
Neurosphere
Indian scientist and professor of cancer biology
centres in India. His research includes stem cell biology, spheroids/organoids, DNA repair mechanisms, and the effects of microgravity on radiobiology
Rana_P_Singh
Protein-coding gene in the species Homo sapiens
neuro-oncological ventral antigen 1 (NOVA1) gene into human cortical organoids might promote slower development and higher surface complexity in the
NOVA1
Psychological focus, perception and prioritising discrete information
in attention: An investigation through computational modelling". Brain Organoid and Systems Neuroscience Journal. 3: 1–7. doi:10.1016/j.bosn.2025.01.001
Attention
Italian chemist
cell reprogramming and disease. Her early work considered intestinal organoids and how they develop from stem cells. In June 2022, Liberali was awarded
Prisca_Liberali
American engineering researcher
the forefront of infection modeling and drug discovery". Biomaterials. Organoids and Ex Vivo Tissue On-Chip Technologies. 198: 228–249. doi:10.1016/j.biomaterials
Thomas_J._Webster
Research University in Kolkata, India
campus have achieved a pioneering breakthrough by developing human brain organoids to investigate Spinocerebellar Ataxia Type-12. By reprogramming patient
The Chatterjee Group Centres for Research and Education in Science and Technology
The_Chatterjee_Group_Centres_for_Research_and_Education_in_Science_and_Technology
Multipotent stem cell in the adult body
and distal airway epithelia. After being developed in 3D cultures, the organoids were separated into individual cells to form 2D monolayers. These lung
Adult_stem_cell
Research institute in Germany
division, lipid rafts, endocytosis, embryogenesis, regeneration, tissue and organoid development. The MPI-CBG is headed by six tenured directors or group leaders
Max Planck Institute of Molecular Cell Biology and Genetics
Max_Planck_Institute_of_Molecular_Cell_Biology_and_Genetics
Norwegian medical researcher (born 1964)
futility. Reproductive technologies, biobanks, organ transplantation, organoids, and artificial intelligence (AI/ML) have been his main topics in the
Bjørn_Hofmann
Scientists coalesced recent developments using human brain organoids into a new field they term organoid intelligence (OI), seeking to harness OI for computing
Timeline of computing 2020–present
Timeline_of_computing_2020–present
Professor at University of Oslo, Norway
includes preclinical work on WNT signalling pathway inhibitors, liver organoid development, integration on chip, microphysiological systems for modeling
Stefan_Krauss_Deiml
German physician and biotechnologist (born 1964)
micro-organoid in vitro technologies,” as follows: Organs are built up by multiple, identical, functionally self-reliant structural micro-organoid units
Uwe_Marx
All Latin and Greek roots beginning with E
microorganism, organ, organic, organism, organist, organize, organogenesis, organoid, organoleptic, orgiastic, orgy, parergon, surgeon, synergism, synergy,
List of Greek and Latin roots in English/E
List_of_Greek_and_Latin_roots_in_English/E
Male reproductive organ cancer
and −2b. Research requiring more complex models of the prostate uses organoids – clusters of prostate cells that can be grown from human prostate tumors
Prostate_cancer
Medication
a non-prostanoid EP2 receptor agonist, induces enlargement of the 3D organoid of 3T3-L1 cells". Scientific Reports. 10 (1) 16018. Bibcode:2020NatSR.
Omidenepag
American composer (1931–2021)
on cerebral organoids cultured from Lucier's white blood cells was opened at the Art Gallery of Western Australia. The cerebral organoids made from Lucier's
Alvin_Lucier
American youtube personality
Angeles finals. She is a co-author of a peer-reviewed study on intestinal organoids derived from human embryonic stem cells related to inflammatory bowel
Natalie_Duran
Diseases of humans caused by a pathogen
through bioinformatics and modeling infections in porcine intestinal organoids". Veterinary Microbiology. 293 110101. doi:10.1016/j.vetmic.2024.110101
Zoonosis
Species of bacteria
inhibit the inflammation that leads to the associated diseases. Gastric organoids can be used as models for the study of H. pylori pathogenesis. Research
Helicobacter_pylori
German artist
Scanning electron microscope (SEM) images of tumor organoids
Andreas_Greiner
Cell that differentiates into one or a few cell types
(October 2016). "Building brains in a dish: Prospects for growing cerebral organoids from stem cells". Neuroscience. 334: 105–118. doi:10.1016/j.neuroscience
Progenitor_cell
Global health science project
liver, and immune system. Draft atlases from the HCA Lung, Nervous System, Organoid and Eye Biological Networks have been assembled by HCA researchers collaborating
Human_Cell_Atlas
Interdisciplinary branch of biology and engineering
combinatorial design, and rational design. Synthetic biology has been used for organoids, which are lab-grown organs with application to medical research and transplantation
Synthetic_biology
Ethics of neuroscience, and the neuroscience of ethics
derived organoids into other animal models. For example, potential future concerns of this type were described when human brain tissue organoids were transplanted
Neuroethics
Synthetic, biodegradable polyester
; LaBarbera, D. V. (2017-01-01), "2.16 - 3D High-Content Screening of Organoids for Drug Discovery", in Chackalamannil, Samuel; Rotella, David; Ward,
Polycaprolactone
Hormonal disorder affecting the female repoductive system
can then be specified to replicate PMOS-like traits. Furthermore, 3D "organoid" models of female reproductive tissue, such as the uterus and ovaries,
Polyendocrine metabolic ovarian syndrome
Polyendocrine_metabolic_ovarian_syndrome
Nevus comedonicus syndrome Nevus sebaceous (nevus sebaceous of Jadassohn, organoid nevus) Nevus unius lateris Nodular basal cell carcinoma (classic basal
List_of_skin_conditions
American neurosurgeon
successfully implanted brain organoids into rodents. Dr. Chen has made notable contributions to the field of human brain organoids. His work in the Cell journal
Isaac_Chen
Saudi bioengineer and engineering education researcher
Inventor Award (2008) Scientific career Fields Bioengineering, Microrobotics, Organoid systems, Engineering education Institutions University of California, San
Reem_Khojah
Matrix for Developing a Cost‐Effective Xenofree Hepatocellular Carcinoma Organoid Model Label-free live-cell-based electrochemical nano-biosensor for monitoring
Nagwa_El-Badri
Award
scientist Hans Clevers. A biologist and immunologist, Clevers's research into organoid technology has earned him recognition from the scientific community. He
Abarca_Prize
Hospital in Baltimore, Maryland, US
Kim, SujungJun; Li, Jiaxin (2021). "Stem cell-derived three-dimensional (organoid) models of Alzheimer's disease: a precision medicine approach". Neural
Johns Hopkins Bayview Medical Center
Johns_Hopkins_Bayview_Medical_Center
American material scientist
adult stem cells, was selected by the National Eye Institute's 3-D Retina Organoid Challenge. She contributed to the 2013 Elsevier book Retina, talking about
Erin_Lavik
cutting-edge technologies for stem cell biology, stem cell differentiation, organoid formation, and induced pluripotent stem cells. This unit collaborates with
Centre_for_Genomic_Regulation
Mouse used for scientific research
Svetlana (2019-08-21). "Copper Transport and Disease: What Can We Learn from Organoids?". Annual Review of Nutrition. 39 (1). Annual Reviews: 75–94. doi:10
Laboratory_mouse
Spanish biochemist and developmental biologist
the differentiation of human stem cells into various cells types and organoids, like the kidney and heart. Development of novel stem cell models of human
Juan_Carlos_Izpisua_Belmonte
Protein-coding gene in the species Homo sapiens
gene corrected before differentiating both stem cell lines into kidney organoids for transcriptional comparison. Aside from validating the club shaped
IFT140
ORGANOID
ORGANOID
ORGANOID
ORGANOID
Girl/Female
Tamil
The intelligent
Boy/Male
Hindu, Indian
Wheat Juice
Boy/Male
German
Land; Form of Lawrence; Crowned with Laurels
Surname or Lastname
Dutch
Dutch : from a reduced form of any of various Germanic personal names formed with the element bald (see Bald).English : variant spelling of Ball 1.Danish : habitational name from a farmstead named Balle, meaning ‘slope’, ‘hill’.Catalan : respelling of Batlle, status name for a steward or official, from Catalan batlle.
Boy/Male
Gaelic
Worships the saints.
Boy/Male
Hindu, Indian
Lord of the Seas
Boy/Male
Arabic, Muslim
Ranks; Praises
Girl/Female
Irish
Great.
Boy/Male
Celebrity, Christian, Greek, Hindu, Indian, Latin, Tamil
Twin
Girl/Female
Muslim
Flourishing, Blossoming
ORGANOID
ORGANOID
ORGANOID
ORGANOID
ORGANOID