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POLR2A

  • POLR2A
  • Protein-coding gene in the species Homo sapiens

    II subunit RPB1, also known as RPB1, is an enzyme that is encoded by the POLR2A gene in humans. This gene encodes the largest subunit of RNA polymerase

    POLR2A

    POLR2A

    POLR2A

  • RNA polymerase II holoenzyme
  • Form of eukaryotic RNA polymerase II

    RNAP II consists of seventeen protein molecules (gene products encoded by POLR2A-L, where the proteins synthesized from POLR2C, POLR2E, and POLR2F form homodimers)

    RNA polymerase II holoenzyme

    RNA_polymerase_II_holoenzyme

  • INTS1
  • Protein-coding gene in the species Homo sapiens

    associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1

    INTS1

    INTS1

    INTS1

  • RNA polymerase II
  • Protein complex for mRNA transcription

    polymerase II subunit RPB1 – an enzyme that in humans is encoded by the POLR2A gene and in yeast is encoded by RPO21. RPB1 is the largest subunit of RNA

    RNA polymerase II

    RNA polymerase II

    RNA_polymerase_II

  • INTS12
  • Protein-coding gene in the species Homo sapiens

    associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and

    INTS12

    INTS12

    INTS12

  • TCEA1
  • Human protein-coding gene

    the non-homologous Gre. TCEA1 has been shown to interact with GTF2H1 and POLR2A. GRCh38: Ensembl release 89: ENSG00000187735 – Ensembl, May 2017 GRCm38:

    TCEA1

    TCEA1

    TCEA1

  • BRCA1
  • Gene known for its role in breast cancer

    MED17 MED21 MRE11A MSH2 MSH3 MSH6 Myc NBN NMI NPM1 NCOA2 NUFIP1 P53 PALB2 POLR2A PPP1CA Rad50 RAD51 RBBP4 RBBP7 RBBP8 RELA RB1 RBL1 RBL2 RPL31 SMARCA4 SMARCB1

    BRCA1

    BRCA1

    BRCA1

  • SMYD3
  • Protein-coding gene in the species Homo sapiens

    interact with Heat shock protein 90kDa alpha (cytosolic), member A1 and POLR2A. SMYD3 trimethylates a lysine residue on MAP3K2, which causes crosstalk

    SMYD3

    SMYD3

    SMYD3

  • SMARCA2
  • Protein-coding gene in the species Homo sapiens

    polymorphism. SMARCA2 has been shown to interact with: ACTL6A, ARID1B, CEBPB, POLR2A, Prohibitin, SIN3A, SMARCB1, SMARCC1, and SS18. - Nicolaides Baraitser Syndrome

    SMARCA2

    SMARCA2

    SMARCA2

  • Housekeeping gene
  • Gene which maintains basic cellular functions

    MRPS31 MRPS33 MRPS34 MRPS35 MRPS5 MRPS6 MRPS7 MRPS9 POLR1C POLR1D POLR1E POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L

    Housekeeping gene

    Housekeeping_gene

  • TATA-binding protein
  • Protein-coding gene in the species Homo sapiens

    (TFIIF subunit 1) GTF2H4 (TFIIH subunit 4), Mdm2, MSX1, NFYB, P53, PAX6, POLR2A, POU2F1, RELA, NR2B1, TAF1, TAF4, TAF5, TAF6, TAF7, TAF9. TAF10, TAF11,

    TATA-binding protein

    TATA-binding protein

    TATA-binding_protein

  • PCAF
  • Protein-coding gene in humans

    BRCA2, CTNNB1, CREBBP, EVI1, HNF1A, IRF1, IRF2, KLF13, Mdm2 Myc, NCOA1, POLR2A, RBPJ, TCF3, TRRAP, and TWIST1. Transcription coregulator Acetyltransferase

    PCAF

    PCAF

    PCAF

  • SMARCA4
  • Protein-coding gene in the species Homo sapiens

    CTNNB1, CBX5, CREBBP, CCNE1, ESR1, FANCA, HSP90B1, ING1, Myc, NR3C1, P53, POLR2A, PHB, SIN3A, SMARCB1, SMARCC1, SMARCC2, SMARCE1, STAT2, and STK11. GRCh38:

    SMARCA4

    SMARCA4

    SMARCA4

  • CDC73
  • Protein-coding gene in humans

    PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. Mutations in the CDC73 gene

    CDC73

    CDC73

    CDC73

  • Transcription elongation regulator 1
  • Protein-coding gene in the species Homo sapiens

    Transcription elongation regulator 1 has been shown to interact with SF1 and POLR2A. GRCh38: Ensembl release 89: ENSG00000113649 – Ensembl, May 2017 GRCm38:

    Transcription elongation regulator 1

    Transcription elongation regulator 1

    Transcription_elongation_regulator_1

  • SND1
  • Protein and coding gene in humans

    by Mir-184 in gliomas. SND1 has been shown to interact with MYB, PIM1, POLR2A, RBPJ, and STAT6. SND1 also interacts with G3BP (stress granule protein)

    SND1

    SND1

    SND1

  • ZNF74
  • Protein-coding gene in the species Homo sapiens

    with a mutation in this protein. ZNF74 has been shown to interact with POLR2A. GRCh38: Ensembl release 89: ENSG00000185252 – Ensembl, May 2017 "Human

    ZNF74

    ZNF74

    ZNF74

  • CTDP1
  • been shown to interact with WD repeat-containing protein 77, GTF2F1 and POLR2A. ENSG00000060069 GRCh38: Ensembl release 89: ENSG00000282752, ENSG00000060069

    CTDP1

    CTDP1

    CTDP1

  • SUPT5H
  • Protein-coding gene in the species Homo sapiens

    shown to interact with: CDK9, Cyclin-dependent kinase 7, HTATSF1, PIN1, POLR2A, PRMT1 and Protein arginine methyltransferase 5. GRCh38: Ensembl release

    SUPT5H

    SUPT5H

    SUPT5H

  • POLR2H
  • Protein-coding gene in the species Homo sapiens

    polymerases, I and III. POLR2H has been shown to interact with POLR2C, POLR2G, POLR2A, POLR2B and POLR2E. GRCh38: Ensembl release 89: ENSG00000163882 – Ensembl

    POLR2H

    POLR2H

    POLR2H

  • TAF11
  • Protein-coding gene in the species Homo sapiens

    arranged as in histone H3. TAF11 has been shown to interact with: GTF2F1, POLR2A and TAF13, TAF15, TATA binding protein, and Transcription Factor II B. GRCh38:

    TAF11

    TAF11

    TAF11

  • GTF2H4
  • Protein-coding gene in the species Homo sapiens

    the GTF2H4 gene. GTF2H4 has been shown to interact with: GTF2F1, MED21, POLR2A, TATA binding protein, Transcription Factor II B, and XPB. Transcription

    GTF2H4

    GTF2H4

    GTF2H4

  • MED26
  • Protein-coding gene in the species Homo sapiens

    MED26 has been shown to interact with MED8, Cyclin-dependent kinase 8, POLR2A, MED12 and MED28. It also acts synergistically to mediate the interaction

    MED26

    MED26

    MED26

  • Cyclin-dependent kinase 8
  • Protein-coding gene in the species Homo sapiens

    CRSP3 MED1 MED12 MED14 MED16 MED17 MED21 MED24 MED26 MED6 Notch proteins POLR2A SMARCB1 STAT1 SREBP GRCh38: Ensembl release 89: ENSG00000132964 – Ensembl

    Cyclin-dependent kinase 8

    Cyclin-dependent kinase 8

    Cyclin-dependent_kinase_8

  • THAP3
  • Protein in Humans

    capture - mass spectrometry Functional PKN1 two hybrid assay Functional POLR2A two hybrid assay Functional TARDBP two hybrid assay Functional Neuronal

    THAP3

    THAP3

    THAP3

  • MED21
  • Protein-coding gene in the species Homo sapiens

    has been shown to interact with: BRCA1, CDK8, GTF2F1, GTF2H4, MED6, and POLR2A. GRCh38: Ensembl release 89: ENSG00000152944 – Ensembl, May 2017 GRCm38:

    MED21

    MED21

    MED21

  • GTF2F1
  • Protein-coding gene in the species Homo sapiens

    gene. GTF2F1 has been shown to interact with: CTDP1, GTF2H4, HNRPU, MED21, POLR2A, Serum response factor TAF11, TAF1, TATA binding protein, and Transcription

    GTF2F1

    GTF2F1

    GTF2F1

  • POLR2L
  • Protein-coding gene in the species Homo sapiens

    DNA-directed RNA polymerases. POLR2L has been shown to interact with POLR2C, POLR2A, POLR2B and POLR2E. GRCh38: Ensembl release 89: ENSG00000177700 – Ensembl

    POLR2L

    POLR2L

    POLR2L

  • ZNF337
  • Protein-coding gene in the species Homo sapiens

    (myelogenous leukemia cells) Promoter MYC K562 (myelogenous leukemia cells) Promoter POLR2A Body of Pancreas Promoter FOS Endothelial Cell of Umbilical Vein

    ZNF337

    ZNF337

    ZNF337

  • SMARCB1
  • Protein-coding gene in the species Homo sapiens

    BAZ1B, BRCA1, CREB-binding protein, Cyclin-dependent kinase 8, Myc, P53, POLR2A, PPP1CA, PPP1CB, PPP1CC, PPP1R15A, SMARCA2, SMARCA4, SMARCC1, SMARCE1, SS18

    SMARCB1

    SMARCB1

    SMARCB1

  • List of human protein-coding genes 6
  • Q3B726 12495 POLR1G HGNC:24219; O15446 12496 POLR1H HGNC:13182; Q9P1U0 12497 POLR2A HGNC:9187; P24928 12498 POLR2B HGNC:9188; P30876 12499 POLR2C HGNC:9189;

    List of human protein-coding genes 6

    List_of_human_protein-coding_genes_6

  • POLR2E
  • Protein-coding gene in the species Homo sapiens

    POLR2E has been shown to interact with TAF15, POLR2C, POLR2G, POLR2H, POLR2A, POLR2B, POLR2L and GTF2F2. GRCh38: Ensembl release 89: ENSG00000099817

    POLR2E

    POLR2E

    POLR2E

  • POLR2C
  • Protein-coding gene in the species Homo sapiens

    chromosome 21. POLR2C has been shown to interact with: ATF4, CCHCR1, Myogenin, POLR2A, POLR2B, POLR2E and POLR2F, POLR2G, POLR2H, POLR2J, POLR2K, POLR2L, and

    POLR2C

    POLR2C

    POLR2C

  • Heat shock protein 90kDa alpha (cytosolic), member A1
  • Protein-coding gene in the species Homo sapiens

    genome indicates that at least 85 unique TFs bind to the RNA polymerase II (POLR2A) footprints associated with the promoter regions that drive the expression

    Heat shock protein 90kDa alpha (cytosolic), member A1

    Heat shock protein 90kDa alpha (cytosolic), member A1

    Heat_shock_protein_90kDa_alpha_(cytosolic),_member_A1

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Online names & meanings

  • Suedge
  • Boy/Male

    English, Modern

    Suedge

    Sharp

  • Riyasat |
  • Boy/Male

    Muslim

    Riyasat |

    Rule, Dominion

  • Mursil
  • Boy/Male

    Arabic

    Mursil

    Envoy; Missionary

  • Childres
  • Surname or Lastname

    English

    Childres

    English : metathesized variant of Childers.

  • Guillermo
  • Boy/Male

    Spanish American

    Guillermo

    Resolute protector.

  • Chamanlal
  • Boy/Male

    Assamese, Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu, Traditional

    Chamanlal

    Garden

  • Chintanika
  • Girl/Female

    Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sindhi, Telugu, Traditional

    Chintanika

    Meditation

  • Sawaira
  • Girl/Female

    Arabic

    Sawaira

    Morning

  • Anjusha
  • Girl/Female

    Indian, Telugu

    Anjusha

    Hanuman's Mother Name

  • Tinki | தீநகீ 
  • Girl/Female

    Tamil

    Tinki | தீநகீ 

    Innocent

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POLR2A

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POLR2A