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Intravenous medication used in anesthesia
Propofol is the active component of an intravenous anesthetic used for induction and maintenance of general anesthesia. Propofol was approved[clarification
Propofol
Medical history of American celebrity
comeback concerts scheduled to begin in July 2009, Jackson died of acute propofol and benzodiazepine intoxication after suffering cardiac arrest on June
Health and appearance of Michael Jackson
Health_and_appearance_of_Michael_Jackson
2011 manslaughter trial in California, US
singer's death on June 25, 2009, from a dose of the general anesthetic propofol. The trial, which started on September 27, 2011, was held in the Los Angeles
People_v._Murray
Medical condition
Propofol infusion syndrome (PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative
Propofol_infusion_syndrome
2009 death of American singer
On June 25, 2009, American singer Michael Jackson died of acute propofol intoxication in Los Angeles, California, at the age of 50. His personal physician
Death_of_Michael_Jackson
American physician and convicted felon (born 1953)
death for having inadvertently overdosed him with the surgical anesthetic propofol, which was being improperly used as a bedtime sleep agent. Murray served
Conrad_Murray
Pharmaceutical compound
Propofol hemisuccinate (developmental code names EP-102 and EP-103) is an anesthetic drug which is an ester substituted prodrug of propofol. Propofol
Propofol_hemisuccinate
Intravenous medication used in general anaesthesia
sold under the brand name Cypsedo, is a general anesthetic related to propofol which is used for anesthesia and sedation. The drug is used by intravenous
Cipepofol
British veterinarian
Scottish veterinarian. Glen is the first to have synthesized the anaesthetic propofol. Born in Scotland, Glen grew up on a small farm. He studied veterinary
John_B._Glen
Sneezing in response to numerous stimuli
sneezing during a periocular injection while sedated by propofol is likely caused by the drug. Propofol has been shown to temporarily suppress inhibitory neurons
Photic_sneeze_reflex
Combination drug
and propofol. Both drugs are anesthetic agents. It can be mixed with propofol in the same syringe. The combination appears to be safer than propofol by
Ketofol
Medical intervention
receptors. It takes 40 seconds for the effects of propofol to kick in, and effects last six minutes. Propofol has both sedative and amnestic effects, but provides
Procedural sedation and analgesia
Procedural_sedation_and_analgesia
American singer (1958–2009)
It, a series of comeback concerts, he died in 2009 from an overdose of propofol administered by his personal physician, Conrad Murray. His death caused
Michael_Jackson
General anesthesia method
was done in 1872 using chloral hydrate, and the common anesthetic agent propofol was licensed in 1986. TIVA is currently employed in various procedures
Total_intravenous_anaesthesia
South Korean actress (born 1984)
indicted for illegal use of the narcotic propofol. The Seoul Central District Court found Jang guilty of taking propofol 410 times over six years (or 5.6 times
Jang_Mi-inae
South Korean actress (born 1979)
charged with propofol abuse are tried". Korea JoongAng Daily. Archived from the original on June 12, 2013. Lee, Kyung-min (May 20, 2013). "Propofol scandal
Park_Si-yeon
Barbiturate general anesthetic
of general anesthesia. Its use has been largely replaced with that of propofol, but may retain some popularity as an induction agent for rapid-sequence
Sodium_thiopental
Short-acting anaesthetic and sedative drug
with a 2.5-fold increase in the risk of dying compared with those given propofol. People given etomidate also had significantly greater odds of having cardiovascular
Etomidate
Category of drug
possibility of an action potential. However, some general anesthetics like propofol and high doses of barbiturates may not only be positive allosteric modulators
GABA_receptor_agonist
Benzodiazepine medication
ill people, propofol has been found to be superior to lorazepam both in effectiveness and overall cost; as a result, the use of propofol for this indication
Lorazepam
Benzodiazepine used for anesthesia and procedural sedation
superior to diazepam in impairing memory of endoscopy procedures, but propofol has a quicker recovery time and a better memory-impairing effect. It is
Midazolam
Reduction of irritability or agitation by administration of sedative drugs
drugs which can be used for sedation include isoflurane, diethyl ether, propofol, etomidate, ketamine, pentobarbital, lorazepam and midazolam. Sedation
Sedation
Dissociative anesthetic and anti-depressant
be counteracted by benzodiazepines or propofol administration. Ketofol is a combination of ketamine and propofol. Ketamine is frequently used in severely
Ketamine
2019 documentary film
death. On June 25, 2009, American singer Michael Jackson died of acute propofol and benzodiazepine intoxication at his home on North Carolwood Drive in
Killing_Michael_Jackson
Chemical compound
derivatives and prodrugs of the widely used intravenous anesthetic agent propofol have been developed, of which fospropofol has been found to be the most
Fospropofol
clinical safety of the effect-site target model. Popular TCI models exist for Propofol and the synthetic opioid Remifentanil. The models are based on pharmacokinetic
Target_controlled_infusion
Obsolete sedative-hypnotic
secobarbital, or they can choose to have 2 grams of thiopental or 1 gram of propofol administered intravenously by a doctor, followed by a muscle relaxant.
Secobarbital
Matriarch of Jackson entertainment family (born 1930)
children. On June 25, 2009, Katherine's son Michael died from an overdose of propofol administered by his personal physician, Conrad Murray. In July 2009, Katherine
Katherine_Jackson
Technique used in in vitro fertilization
stomach contents. Propofol-based anesthetic techniques result in significant concentrations of propofol in follicular fluid. As propofol has been shown to
Transvaginal_oocyte_retrieval
South Korean singer (1982–2025)
partook in recreational propofol use. While investigating a tip, the police had come to suspect Wheesung of purchasing propofol and sent his case to the
Wheesung
Anxiolytic, sedative, and pain medication
as an adjunct with other sedatives like benzodiazepines, opioids, and propofol to enhance sedation and help maintain hemodynamic stability by decreasing
Dexmedetomidine
Aminosulfonic acid
L-Alanine L-Proline L-Serine L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone
Taurine
Inhalational anaesthetic
sodium excretion while increasing plasma renin concentrations compared with propofol anaesthesia. To further investigate the underlying mechanism, one study
Sevoflurane
Organic compound used as flavouring and analgesic
Menthol has anesthetic properties similar to, though less potent than, propofol because it interacts with the same sites on the GABAA receptor. Menthol
Menthol
South Korean actress (born 1968)
of the drug propofol. Cable channel Story On cancelled her talk show Lee Seung-yeon and 100 Women as a result. Lee admitted taking propofol, but said it
Lee_Seung-yeon
Medically induced loss of consciousness
fentanyl or a fentanyl derivative) and sedatives (usually propofol or midazolam). Propofol can be used for total intravenous anaesthesia (TIVA), therefore
General_anaesthesia
2nd episode of the 1st season of Into the Dark
one of them gives Kimberly her card. Kimberly goes online to research Propofol, a bottle of which she has found among her father's belongings. Discovering
Flesh_&_Blood_(Into_the_Dark)
Medical condition
medications may be used if these are not effective, such as phenobarbital, propofol, or ketamine. After initial treatment with benzodiazepines, typical antiseizure
Status_epilepticus
Concerts by American singer-songwriter Michael Jackson
economy. While preparing for the concerts, Jackson died from an overdose of propofol administered by his personal physician, Conrad Murray. Michael Jackson
List of Michael Jackson concerts
List_of_Michael_Jackson_concerts
Topics referred to by the same term
Society, in Canada Power Rangers in Space, an American television series Propofol infusion syndrome Pris Stratton, a character in Philip K. Dick's novel
Pris
Benzodiazepine medication
Reichhart MD, Schaller MD, Despland PA, Bogousslavsky J (July 2004). "Propofol treatment of refractory status epilepticus: a study of 31 episodes". Epilepsia
Clonazepam
American actress and model (1943–1969)
murder-suicide Michael Jackson – American singer (1958–2009), killed on acute propofol intoxication by his physician Conrad Murray John Lennon – English musician
Sharon_Tate
Tranquilizer based with herbs Valerian, hops, peppermint & phenobarbital, a barbiturate
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Corvalol
Special process for endotracheal intubation
the body quickly. In the elderly, the rate of Propofol clearance is low. Therefore, lower doses of Propofol (50 to 100 mg) should be given. It is suitable
Rapid_sequence_induction
Veterinary anesthetic, sedative and analgesic
including lidocaine, naloxone, thiamine, lorazepam, vecuronium, etomidate, propofol, tolazoline, yohimbine, atropine, orciprenaline, metoclopramide, ranitidine
Xylazine
Inhalational anesthesia medication
Desflurane is administered alongside other anesthetics like midazolam and propofol, analgesics, as well as air and oxygen for balanced anesthesia. Unlike
Desflurane
South Korean singer
Seulgi of Red Velvet. In July 2021, Gain apologized for illegally using propofol, an anesthetic drug prohibited from being used for purposes other than
Gain_(singer)
Component of body composition
patient, opioids are best based on lean body weight. The induction dose of propofol should also be based on LBW. LBM is usually estimated using mathematical
Lean_body_mass
Hypnotic medication
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Eszopiclone
Technology for monitoring anesthesia
PACU Reduced risk of postoperative nausea and vomiting Reduced use of propofol Reduced risk of awareness, although this claim is questioned by some studies
Bispectral_index
2005 child abuse trial of American singer
Four years after his acquittal, on June 25, 2009, Jackson died of acute propofol and benzodiazepine intoxication at his home in Holmby Hills, Los Angeles
Trial_of_Michael_Jackson
How drugs induce reversible suppression of consciousness
nervous system. However, for certain intravenous anaesthetics, such as propofol and etomidate, the main molecular target is believed to be GABAA receptor
Theories of general anaesthetic action
Theories_of_general_anaesthetic_action
State of medically-controlled temporary loss of sensation or awareness
odds of dying in the first seven days after anesthetic. For instance, propofol (injection) might be used to start the anesthetic, fentanyl (injection)
Anesthesia
Main inhibitory neurotransmitter in the mammalian brain
anesthetics work by changing how GABA acts in the brain. Drugs such as propofol, etomidate, barbiturates, and many gases like isoflurane and sevoflurane
GABA
Class of CNS depressant drugs
of commonly used analgesics and sedatives in the ICU: benzodiazepines, propofol, and opioids". Critical Care Clinics. 25 (3): 431–49, vii. doi:10.1016/j
Benzodiazepine
Anesthetic technique
drugs such as ketamine (pediatrics primarily, and infrequently in adults), propofol, and midazolam. Twilight anesthesia alone is not used to provide relief
Twilight_anesthesia
American and Canadian actor (1969–2023)
hydrocodone per day and was having daily ketamine infusions. He was given propofol in conjunction with a surgery, which stopped his heart for five minutes
Matthew_Perry
South Korean business executive (born 1968)
riding. On October 26, 2021, Lee was convicted for illegally using the drug propofol multiple times between 2015 and 2020 from a plastic surgery clinic. He
Lee_Jae-yong
American multinational healthcare company
wrongly reused dirty medical supplies to administer propofol to patients, although the label for propofol clearly states that it is for single-patient use
Baxter_International
2025 film by Kang Hyeong-cheol
but it was postponed indefinitely after Yoo Ah-in tested positive for propofol and marijuana in February 2023. Later in June 2023, Next Entertainment
Hi-Five_(film)
Drugs that lower neurotransmission levels, reducing brain activity
Anesthetics are generally depressants; examples include ketamine and propofol. Depressants exert their effects through a number of different pharmacological
Depressant
Synthetic opioid analgesic
however, it is not as effective as epidural analgesia. In combination with propofol, remifentanil is used for anesthesia of patients undergoing electroconvulsive
Remifentanil
Chemical compound
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Barbital
Statin medication
mononitrate Metoprolol Motavizumab Olaparib Omeprazole Osimertinib Palivizumab Propofol Quetiapine Ravulizumab Roflumilast Rosuvastatin Roxadustat Salbutamol/budesonide
Rosuvastatin
Poisonous substance used as pesticide
phenobarbital or diazepam, muscle relaxants such as dantrolene, barbiturates and propofol, and chloroform or heavy doses of chloral, bromide, urethane or amyl nitrite
Strychnine
Obsolete sedative–hypnotic drug
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Methaqualone
Chimpanzee once owned by Michael Jackson
in painting. On June 25, 2009, Jackson died at the age of 50 of acute propofol intoxication. Dunn, speaking to the News of the World, said: "Bubbles definitely
Bubbles_(chimpanzee)
Jackson, American musician (25 June 2009), asking his doctor for more propofol shortly before he died from an overdose of the same drug. "Say goodnight
List of last words (21st century)
List_of_last_words_(21st_century)
Chemical compound
the commonly used sedative anaesthetic agent, propofol. 4-Iodopropofol has similar effects to propofol on isolated receptors, acting primarily as a GABAA
4-Iodopropofol
Drug that reduces excitement without inducing sleep
Methoxyflurane (Penthrox) Nitrous oxide ("Laughing gas") Phencyclidine (PCP) Propofol (Diprivan) Sevoflurane (Sevorane) Xenon Herbal sedatives Calea ternifolia
Sedative
South Korean actor (born 1986)
examinations. On February 8, 2023, Yoo was questioned by the police for propofol use, and would share more details and promise to cooperate with all investigations
Yoo_Ah-in
Medical procedure
or thiopental. Other intravenous anesthetic drugs such as midazolam or propofol may be used. Drug-induced comas are used to protect the brain during major
Induced_coma
Electrical shock or medications to interrupt cardiac arrhythmia
, propofol) in order to ensure patient comfort and amnesia during the procedure. Opioid analgesics (e.g., fentanyl) may be combined with propofol, although
Cardioversion
Disorder causing trouble with sleeping
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Insomnia
Chemical compound
Honokiol is a small, hydrophobic neolignan biphenol structurally similar to propofol that can be purified efficiently from its isomer magnolol using advanced
Honokiol
Calendar year
concerts were supposed to begin, Jackson died at the age of 50 from acute propofol intoxication. March 7 – NASA's Kepler Mission, a space photometer that
2009
Benzodiazepine drug
U-89843A U-90042 Viqualine Y-23684 Phenols Cipepofol Fospropofol Propofol Propofol hemisuccinate Thymol Piperidinediones Glutethimide Methyprylon Piperidione
Bromazepam
Chemical compound
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Tert-Butyl_alcohol
Benzodiazepine sedative
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Flunitrazepam
Alkene gas naturally regulating the plant growth
U-89843A U-90042 Viqualine Y-23684 Phenols Cipepofol Fospropofol Propofol Propofol hemisuccinate Thymol Piperidinediones Glutethimide Methyprylon Piperidione
Ethylene_(plant_hormone)
Drug that causes anesthesia
the UK) Benzodiazepines Diazepam Lorazepam Midazolam Etomidate Ketamine Propofol Among the barbiturates mentioned above, thiopental and methohexital are
Anesthetic
Sleep medication
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Zolpidem
French businessman
mononitrate Metoprolol Motavizumab Olaparib Omeprazole Osimertinib Palivizumab Propofol Quetiapine Ravulizumab Roflumilast Rosuvastatin Roxadustat Salbutamol/budesonide
Pascal_Soriot
Chemical sedative and hypnotic drug
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Chloral_hydrate
Ionotropic receptor and ligand-gated ion channel
niacin/niacinamide, nonbenzodiazepines (e.g., zolpidem, eszopiclone), propofol, stiripentol, theanine,[citation needed] valerenic acid, volatile/inhaled
GABAA_receptor
Action used to slow down the heart rate by stimulating the vagus nerve
(December 2018). "Evaluation of efficacy of Valsalva maneuver for attenuating propofol injection pain: a prospective, randomized, single blind, placebo controlled
Vagal_maneuver
Brand name for polyethoxylated castor oil
USP)[citation needed] Nelfinavir mesylate, HIV protease inhibitor[citation needed] Propofol, intravenous anaesthetic agent, originally solublized with Cremophor EL
Kolliphor_EL
Naturally occurring sedative and hallucinogen
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Muscimol
Triazolobenzodiazepine sleep medication
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Triazolam
Fluoroquinolone antibiotic
allopregnanolone) Org 20599 PF-6372865 Phenibut Picamilon 4-PIOL P4S Progabide Propofol Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thio-4-PIOL
Ciprofloxacin
Drug whose use induces sleep
urethane (ethyl carbamate), isoflurane, allopregnanolone (brexanolone), and propofol, among others. The GABAA receptor agonist gaboxadol (THIP; LU-2-030), a
Hypnotic
Chemical compound
U-89843A U-90042 Viqualine Y-23684 Phenols Cipepofol Fospropofol Propofol Propofol hemisuccinate Thymol Piperidinediones Glutethimide Methyprylon Piperidione
Deuterated_etifoxine
Technique in anesthesia
fentanyl which has a fast onset, then an intravenous induction agent: propofol. A muscle relaxant such as atracurium would be administered after this
Coinduction_(anesthetics)
Chemical compound (C4H9OH)
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
1-Butanol
2010 American TV series or program
combination of prescription medications and a heavy-duty anesthesia drug called Propofol, all administered by a mysterious physician who was treating Jackson at
Famous_Crime_Scene
Muscle relaxant medication
Zaleplon Zolpidem Zopiclone Phenols Cipepofol (ciprofol) Fospropofol Propofol Propofol hemisuccinate Piperidinediones Glutethimide Methyprylon Piperidione
Tizanidine
Index of chemical compounds with the same molecular formula
u) may refer to: Amylmetacresol (AMC) 2,4-Dimethyl-6-tert-butylphenol Propofol This set index page lists chemical structure articles associated with the
C12H18O
Drug class
allopregnanolone) Org 20599 PF-6372865 Phenibut Picamilon 4-PIOL P4S Progabide Propofol Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thio-4-PIOL
GABAA receptor negative allosteric modulator
GABAA_receptor_negative_allosteric_modulator
Harmful effect resulting from a medication or other medical intervention
gentamicin (an antibiotic) Death, following sedation, in children using propofol (Diprivan) Depression or hepatic injury caused by interferon Diabetes caused
Adverse_effect
Chemical compound
anesthetic drugs, including propanidid (later withdrawn) and the widely used propofol. Eugenol and the structurally similar myristicin have the common property
Eugenol
PROPOFOL
PROPOFOL
PROPOFOL
PROPOFOL
Boy/Male
Hindu
Affectionate, Kind
Boy/Male
Arabic, Muslim
Spirit of the Holy
Girl/Female
Muslim
A tree which yields An Aroma
Boy/Male
Tamil
Moderate, Average
Girl/Female
Arabic
Bird
Male
Dutch
, addition, or, he will add.Â
Boy/Male
Hindu, Indian
A Chief; Leader; Head of Group
Boy/Male
Russian
God's gift.
Boy/Male
Arabic
Tiger
Girl/Female
Australian, Finnish, French, German, Greek, Japanese, Swedish
Wise; Wisdom
PROPOFOL
PROPOFOL
PROPOFOL
PROPOFOL
PROPOFOL