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a protein structure database is a database that is modeled around the various experimentally determined protein structures. The aim of most protein structure
Protein_structure_database
Three-dimensional arrangement of atoms in an amino acid-chain molecule
Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers – specifically polypeptides – formed
Protein_structure
Artificial intelligence program by DeepMind
DeepMind, a subsidiary of Alphabet, which performs predictions of protein structure. It is designed using deep learning techniques. AlphaFold 1 (2018)
AlphaFold
Type of biological prediction
Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of
Protein_structure_prediction
Biological database of proteins
Classification of Proteins (SCOP) database is a largely manual classification of protein structural domains based on similarities of their structures and amino
Structural Classification of Proteins database
Structural_Classification_of_Proteins_database
International open access database of large biological molecules
structure data to the PDB. Many other databases use protein structures deposited in the PDB. For example, SCOP and CATH classify protein structures,
Protein_Data_Bank
Topics referred to by the same term
Protein database may refer to: Any protein structure database Any protein sequence database Exact names "Protein" database of the National Institute of
Protein_database
database, integrating information from 12 others Entrez search system at the National Center for Biotechnology Information (NCBI) link Expert Protein
List_of_biological_databases
Centre for research
biomacromolecule primary structure, most often nucleotide sequence of DNA/RN, and amino acid sequence of proteins, stored in the bioinformatic databases, with the query
European Bioinformatics Institute
European_Bioinformatics_Institute
Three dimensional shape of a protein
Protein tertiary structure is the three-dimensional shape of a protein. The tertiary structure will have a single polypeptide chain "backbone" with one
Protein_tertiary_structure
Biomolecule consisting of chains of amino acid residues
responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily
Protein
Genomics database
The Open Protein Structure Annotation Network (TOPSAN) is a wiki designed to collect, share and distribute information about protein three-dimensional
Open protein structure annotation network
Open_protein_structure_annotation_network
Number and arrangement of multiple folded protein subunits in a multi-subunit complex
Protein quaternary structure is the fourth (and highest) classification level of protein structure. Protein quaternary structure refers to the structure
Protein_quaternary_structure
The CATH Protein Structure Classification database is a free, publicly available online resource that provides information on the evolutionary relationships
CATH_database
Database of protein structures
Orientations of Proteins in Membranes (OPM) database provides spatial positions of membrane protein structures with respect to the lipid bilayer. Positions
Orientations of Proteins in Membranes database
Orientations_of_Proteins_in_Membranes_database
Proteins or FSSP is a database of structurally superimposed proteins generated using the "Distance-matrix ALIgnment" (DALI) algorithm. The database currently
Families of Structurally Similar Proteins database
Families_of_Structurally_Similar_Proteins_database
Software company in Canada
PSILO: A Protein Structure Database System PSILO is a protein structure database system that provides a repository for macromolecular and protein-ligand
Chemical_Computing_Group
Database of biological information
problem, as many databases must store the same information, e.g. protein structure databases also contain the sequence of the proteins they cover, their
Biological_database
Protein without a fixed 3D structure
biology, an intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure, typically in the absence of its
Intrinsically disordered proteins
Intrinsically_disordered_proteins
(Homology-derived Secondary Structure of Proteins) is a database that combines structural and sequence information about proteins. This database has the information
Homology-derived Secondary Structure of Proteins
Homology-derived_Secondary_Structure_of_Proteins
The Database of protein conformational diversity (PCDB) is a database of diversity of protein tertiary structures within protein domains as determined
Database of protein conformational diversity
Database_of_protein_conformational_diversity
Linear sequence of amino acids in a peptide or protein
Protein primary structure is the linear sequence of amino acids in a peptide or protein. By convention, the primary structure of a protein is reported
Protein_primary_structure
The Structure atlas of human genome (SAHG) is a database of protein-structure-prediction. Protein structure Motono C, Nakata J, Koike R, Shimizu K, Shirota
Structure atlas of human genome
Structure_atlas_of_human_genome
American chemist and computer scientist (born 1985)
and David Baker were awarded the 2024 Nobel Prize in Chemistry for protein structure prediction. Jumper served as a director at Google DeepMind for nearly
John_M._Jumper
Evolutionary Classification of Protein Domains (ECOD) is a biological database that classifies protein domains available from the Protein Data Bank. The ECOD tries
Evolutionary Classification of Protein Domains
Evolutionary_Classification_of_Protein_Domains
Pictorial database of 3D structures in the Protein Data Bank
PDBsum is a database that provides an overview of the contents of each 3D macromolecular structure deposited in the Protein Data Bank (PDB). The original
PDBsum
Spherical, water-soluble type of protein
2014). "SCOP2 prototype: a new approach to protein structure mining". Nucleic Acids Research. 42 (Database issue): D310-4. doi:10.1093/nar/gkt1242. PMC 3964979
Globular_protein
is a database of predicted and known interactions between protein domains. Version 3.0 of the database was released in 2010. Protein domain Protein–protein
DIMA_(database)
Self-stable region of a protein's chain that folds independently from the rest
biological database covering protein domains Pfam: database of protein domains Protein Protein structure Protein structure prediction Protein structure prediction
Protein_domain
MIPModDB is a database of comparative protein structure models of MIP (Major intrinsic proteins) family of proteins. Gupta, Anjali Bansal; Verma Ravi
MIPModDB
DataBase
in Protein Interfaces Database (PCRPi-DB) is a database of annotated hot spots in protein complexes for which the 3D structure is known. Protein structure
PCRPi-DB
Protein
AlphaFold Protein Structure Database. AlphaFold Protein Structure Database. Retrieved 5 December 2023. NCBI Structure iCN3D. iCn3D: Web-based 3D Structure Viewer
C11orf91
Chemical Shift NMR Protein Protein structure database Protein Chemical Shift Re-Referencing Protein secondary structure Protein Chemical Shift Prediction
SHIFTCOR
Chemical shift index Protein NMR RefDB (chemistry) SHIFTCOR Protein structure database NMR Nuclear magnetic resonance spectroscopy Protein nuclear magnetic
Protein chemical shift re-referencing
Protein_chemical_shift_re-referencing
ProSAS is a database describing the effects of splicing on the structure of a protein Alternative splicing Protein structure Birzele, Fabian; Küffner Robert;
ProSAS
Gene
1018–1024. doi:10.1093/hmg/ddr532. PMID 22080834. "AlphaFold Protein Structure Database". alphafold.ebi.ac.uk. Retrieved 2021-12-18. Wu WY, Johansson
C2orf80
Biological database
domains and full-length proteins. The database consists of position-specific score matrices and serves as resource for protein annotation such as identification
Conserved_Domain_Database
Predicting 3D protein structure from its sequence
computational biology, de novo protein structure prediction refers to an algorithmic process by which protein tertiary structure is predicted from its amino
De novo protein structure prediction
De_novo_protein_structure_prediction
British AI researcher (born 1976)
the Nobel Prize in Chemistry for their AI research contributions to protein structure prediction. Hassabis is a Fellow of the Royal Society and has won
Demis_Hassabis
Grouping of proteins
(January 2002). "SUPFAM--a database of potential protein superfamily relationships derived by comparing sequence-based and structure-based families: implications
Protein_superfamily
Computational analysis of large, complex sets of biological data
design, drug discovery, protein structure alignment, protein structure prediction, prediction of gene expression and protein–protein interactions, genome-wide
Bioinformatics
This list of protein subcellular localisation prediction tools includes software, databases, and web services that are used for protein subcellular localization
List of protein subcellular localization prediction tools
List_of_protein_subcellular_localization_prediction_tools
DOMINE is a database of known and predicted protein domain interactions (or domain-domain interactions). It contains interactions observed in PDB crystal
Domine_Database
Non-soluble proteins with elongated or sheet-like structures
fibrous proteins or scleroproteins are one of the three main classifications of protein structure (alongside globular and membrane proteins). Fibrous
Fibrous_protein
Proteins that are part of, or interact with, biological membranes
list of selected transmembrane proteins from the Protein Data Bank MemProtMD - a database of membrane protein structures simulated by coarse-grained molecular
Membrane_protein
Study of the structure of every protein in a genome
3-dimensional structure of every protein encoded by a given genome. This genome-based approach allows for a high-throughput method of structure determination
Structural_genomics
Predicted output by AlphaFold indicating expected position error of protein structures
Aligned Error (PAE) is a quantitative output produced by AlphaFold, a protein structure prediction system developed by DeepMind, and other similar programs
Predicted_Aligned_Error
Bioinformatician and associate professor at Seoul National University
Foldseek, a tool for protein structure search. Nature Methods described Foldseek as a major acceleration in protein structure database searches, while Nature
Martin_Steinegger_(scientist)
Arrangement of amino acid sequence
relationship between proteins whereby the proteins have a changed order of amino acids in their peptide sequence. The result is a protein structure with different
Circular permutation in proteins
Circular_permutation_in_proteins
The GPCRdb database is the main repository of curated data for G protein-coupled receptors (GPCRs). It integrates various web tools and diagrams for GPCR
G protein-coupled receptors database
G_protein-coupled_receptors_database
AI research laboratory
200 million predicted protein structures, representing virtually all known proteins, would be released on the AlphaFold database. Google DeepMind has become
Google_DeepMind
Bioinformatics subfield
three-dimensional structure of biological macromolecules such as proteins, RNA, and DNA. It deals with generalizations about macromolecular 3D structures such as
Structural_bioinformatics
The PDBbind database is a comprehensive collection of experimentally measured binding affinity data (Kd, Ki, and IC50) for the protein-ligand complexes
PDBbind_database
Database of protein families, domains and functional sites
InterPro is a database of protein families, protein domains and functional sites in which identifiable features found in known proteins can be applied
InterPro
2014). "SCOP2 prototype: a new approach to protein structure mining". Nucleic Acids Research. 42 (Database issue): D310–4. doi:10.1093/nar/gkt1242. PMC 3964979
List_of_proteins
Repository for small molecule crystal structures
complementary to the other crystallographic databases such as the Protein Data Bank (PDB), Inorganic Crystal Structure Database and International Centre for Diffraction
Cambridge_Structural_Database
computational ability to determine protein structure with programs such as AlphaFold, and the demand for the corresponding protein-ligand docking predictions
Protein–ligand_docking
BriX is a database containing some protein fragments from 4 to 14 residue from non-homologous proteins. There are very few loops registered in Brix, so
Brix_(database)
Method of protein structure prediction
as proteins of known structures, but do not have homologous proteins with known structure. It differs from the homology modeling method of structure prediction
Threading_(protein_sequence)
Categories of protein tertiary structure
large classes of protein that are generally agreed upon by the two main structure classification databases (SCOP and CATH). All-α proteins are a class of
Protein_fold_class
Type of membrane protein that is permanently attached to the biological membrane
and crystallization. In addition, structures of many water-soluble protein domains of IMPs are available in the Protein Data Bank. Their membrane-anchoring
Integral_membrane_protein
Organization that maintains the global open access Protein Data Bank
Worldwide Protein Data Bank (wwPDB) is an organization that maintains the archive of macromolecular structure. Its mission is to maintain a single Protein Data
Worldwide_Protein_Data_Bank
SUPERFAMILY is a database and search platform of structural and functional annotation for all proteins and genomes. It classifies amino acid sequences
Superfamily_database
Rational design of new protein molecules
understanding of protein function. Proteins can be designed from scratch (de novo design) or by making calculated variants of a known protein structure and its
Protein_design
Gene in Humans
"AlphaFold Protein Structure Database - ZFP62 (Rattus norvegicus)". alphafold.ebi.ac.uk. Retrieved 2023-12-17. "AlphaFold Protein Structure Database - ZFP62
ZFP62
The RNA-binding Proteins Database (RBPDB) is a biological database of RNA-binding protein specificities that includes experimental observations of RNA-binding
RNA-binding_protein_database
Protein-coding gene in the species Homo sapiens
Transmembrane protein 273 (TMEM273) aka C10orf128, is a protein which in humans is encoded by the TMEM273 gene. This protein is found within the topological
TMEM273
Aligning molecular sequences using sequence and structural information
more polymer structures based on their shape and three-dimensional conformation. This process is usually applied to protein tertiary structures but can also
Structural_alignment
Technique used for determining crystal structures and identifying mineral compounds
Classification of Proteins database CATH Protein Structure Classification List of transmembrane proteins with known 3D structure Archived 2011-04-11 at the
X-ray_crystallography
Class of cell surface receptors coupled to G-protein-associated intracellular signaling
With the determination of the first structure of the complex between a G-protein coupled receptor (GPCR) and a G-protein trimer (Gαβγ) in 2011 a new chapter
G_protein-coupled_receptor
and proteomic research, and scientific studies. It contains protein sequences databases PIR was established in 1984 by the National Biomedical Research
Protein_Information_Resource
Organized collection of data in computing
Casio Databank – Brand of watch Conformational dynamics data bank – Database of protein conformations Data repository – Long-term storage of research dataPages
Database
1). The database was assembled by using a structure-based chemical shift calculation program (called SHIFTX) to calculate expected protein (1)H, (13)C
RefDB_(chemistry)
Protein shell of a virus
has a prolate head structure. The bacteriophage encoded gp31 protein appears to be functionally homologous to E. coli chaperone protein GroES and able to
Capsid
sequence database is a type of biological database that is composed of a large collection of computerized ("digital") nucleic acid sequences, protein sequences
Sequence_database
Human Gene
Jumper, John (2022-01-07). "AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy
SERTM2
Biological database
The database of three-dimensional interacting domains (3did) is a biological database containing a catalogue of protein-protein interactions for which
3did
PDBREPORT database is a database of anomalies and errors found in structures of biological molecules in the Protein Data Bank. The PDBREPORTS database is a
PDBREPORT
Directory of allosteric proteins' structure
Allosteric Database (ASD) provides a central resource for the display, search, and analysis of the structure, function, and related annotation for allosteric
ASD_(database)
Type of common three-dimensional structure in chain-like biological molecules
chain-like biological molecule, such as a protein or nucleic acid, a structural motif is a common three-dimensional structure that appears in a variety of different
Structural_motif
Database of protein sequences and functional information
DC, US, is heir to the oldest protein sequence database, Margaret Dayhoff's Atlas of Protein Sequence and Structure, first published in 1965. In 2002
UniProt
The Biomolecule Stretching Database contains information about the mechanostability of proteins based on their resistance to stretching. Sikora, Mateusz;
Biomolecule Stretching Database
Biomolecule_Stretching_Database
and links to other public databases, features that are unique worldwide. A list of protein entries with solved 3D-structure can be also found in each
OMPdb
Arrangement of interrelated elements in an object/system, or the object/system itself
and their structure has multiple levels. Protein structure has a four-level hierarchy. The primary structure is the sequence of amino acids that make
Structure
Protein structural motif
(β-sheet, also β-pleated sheet) is a common motif of the regular protein secondary structure. Beta sheets consist of beta strands (β-strands) connected laterally
Beta_sheet
Enzyme
the bacterial species Pectobacterium atrosepticum. "AlphaFold Protein Structure Database". alphafold.ebi.ac.uk. "MetaCyc apulose kinase". biocyc.org.
Apulose_kinase
Physical interactions and constructions between multiple proteins
Multiprotein complex Protein domain dynamics Protein flexibility Protein structure Protein–protein interaction prediction Protein–protein interaction screening
Protein–protein_interaction
and hosted by the National Center for Biotechnology Information. Protein structure Madej, Thomas; Addess Kenneth J; Fong Jessica H; Geer Lewis Y; Geer
Molecular_Modeling_Database
Database branch of the US National Library of Medicine
Nucleotide Database: A database of nucleotide sequences. Protein Database: A database of protein sequences. Genome Database: A database that gives you
National Center for Biotechnology Information
National_Center_for_Biotechnology_Information
Group of evolutionarily-related proteins
SCOP and CATH - Classifications of protein structures into superfamilies, families and domains Similarly, many database-searching algorithms exist, for example:
Protein_family
Biological database
Tool (SMART) is a biological database that is used in the identification and analysis of protein domains within protein sequences. SMART uses profile-hidden
Simple Modular Architecture Research Tool
Simple_Modular_Architecture_Research_Tool
Protein emerging once on each face of a lipid bilayer
membrane protein also known as single-spanning protein or bitopic protein is a transmembrane protein that spans the lipid bilayer only once. These proteins may
Single-pass_membrane_protein
Human gene
related family The TMEM62 protein is predicted to be membrane-associated with several transmembrane helices and a compact, structured core. Expression analysis
TMEM62
Carbohydrate Structure Database (CSDB) is a free curated database and service platform in glycoinformatics, launched in 2005 by a group of Russian scientists
Carbohydrate Structure Database
Carbohydrate_Structure_Database
Small structural protein motif found mostly in transcriptional proteins
finger protein's class is determined by its three-dimensional structure, but it can also be recognized based on the primary structure of the protein or the
Zinc_finger
Membrane proteins that adhere temporarily to membranes with which they are associated
Peripheral membrane proteins, or extrinsic membrane proteins, are membrane proteins that adhere only temporarily to the biological membrane with which
Peripheral_membrane_protein
Protein domain
The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. Protein kinases are a group
Protein_kinase_domain
Online biodatabase of proteins
Membranome database provides structural and functional information about more than 6000 single-pass (bitopic) transmembrane proteins from Homo sapiens
Membranome_database
Topics referred to by the same term
FSSP may refer to: Families of structurally similar proteins, a protein structures database Federal Bailiffs Service (Russia), abbreviated FSSP in Russian
FSSP
Protein found in humans
(January 2024). "AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences". Nucleic Acids Research
Zinc_finger_protein_229
PROTEIN STRUCTURE-DATABASE
PROTEIN STRUCTURE-DATABASE
Girl/Female
Arabic, Australian, Muslim
Protect
Boy/Male
Muslim
Solid structure
Boy/Male
Hindu
Boy/Male
Afghan, Arabic, Gujarati, Indian, Muslim
Solid Structure; Lifetime
Boy/Male
Indian
Solid structure
Girl/Female
Tamil
Shape, Structure
Girl/Female
Hindu, Indian, Telugu
The Structure of God
Boy/Male
Indian
Good Structure
Girl/Female
Afghan, Arabic, Australian, Danish, French, Hebrew, Muslim
Protect
Surname or Lastname
English
English : possibly a variant of Porton, a habitational name from Porton in Wiltshire or Poorton in Dorset; both place names are formed with an obscure first element, perhaps the name of a river, + Old English tūn ‘settlement’.Dutch : habitational name for someone from a place named with Dutch poort ‘gate’.
Boy/Male
Greek Shakespearean
A sea god.
Girl/Female
Indian
Shape, Structure
Boy/Male
Bengali, Indian
Love
Girl/Female
Hindu, Indian
Protect
Girl/Female
Indian, Kashmiri
Body Structure
Girl/Female
Indian
Shape, Structure
Girl/Female
Tamil
Shape, Structure
Boy/Male
Bengali, Indian
Symbol
Surname or Lastname
English and French
English and French : regional name from Old French Poitevin, denoting someone from Poitou in western France. The form Potvin has long been established in England and was brought to the U.S. from there. However, French bearers of the surname Poitevin also came to the New World, where their surname underwent a similar transformation on arrival in New England.
Girl/Female
Indian
Structure
PROTEIN STRUCTURE-DATABASE
PROTEIN STRUCTURE-DATABASE
Boy/Male
Hindu, Indian
Palace; One of the Three Worlds
Surname or Lastname
English
English : unexplained.
Girl/Female
Arabic, Muslim, Sindhi
Narrator of Hadith
Boy/Male
English American
Fair town. Abbreviation of Trevelyan.
Surname or Lastname
English
English : habitational name from Moreby in Yorkshire or Moorby in Lincolnshire, both named in Old Scandinavian as ‘farmstead (býr) in the moor or marshland (mór)’.
Boy/Male
Muslim
Authority, King
Boy/Male
Hindu, Indian, Kannada, Malayalam, Marathi
Victory; Light of the Vedas; Light of Vedic Knowledge
Boy/Male
Muslim
Organization, Arrangement
Girl/Female
Hindu, Indian
Hindu Goddess Form of Durga
Surname or Lastname
English, German, and Dutch
English, German, and Dutch : nickname for a lively or agile person, from Middle English quik, Middle High German quick, Middle Dutch quic ‘alive’, ‘lively’, ‘fresh’.English : habitational name for someone who lived at a place called Cowick (notably one in Devon), denoting an outlying dairy farm, from Old English cūwīc, from cū ‘cow’ + wīc ‘outlying settlement’.Cornish : habitational name from Gweek in the parish of Constantine, named from Cornish gwyk, which may have meant either ‘village’ or ‘forest’, or a topographic name from the same word.English : topographic name for someone who lived by a place overgrown with couch grass (Old English cwice).
PROTEIN STRUCTURE-DATABASE
PROTEIN STRUCTURE-DATABASE
PROTEIN STRUCTURE-DATABASE
PROTEIN STRUCTURE-DATABASE
PROTEIN STRUCTURE-DATABASE
a.
Of or pertaining to Proteus; characteristic of Proteus.
n.
Manner of building; form; make; construction.
a.
Of or pertaining to structure; affecting structure; as, a structural error.
v. i.
To make a solemn declaration (often a written one) expressive of opposition; -- with against; as, he protest against your votes.
n.
A localized morbid contraction of any passage of the body. Cf. Organic stricture, and Spasmodic stricture, under Organic, and Spasmodic.
n.
One of a class of amorphous nitrogenous principles, containing, as a rule, a small amount of sulphur; an albuminoid, as blood fibrin, casein of milk, etc. Proteids are present in nearly all animal fluids and make up the greater part of animal tissues and organs. They are also important constituents of vegetable tissues. See 2d Note under Food.
n.
A body now known as alkali albumin, but originally considered to be the basis of all albuminous substances, whence its name.
n.
A touch of adverse criticism; censure.
a.
Of or pertaining to organit structure; as, a structural element or cell; the structural peculiarities of an animal or a plant.
a.
Affected with a stricture; as, a strictured duct.
n.
That which is built; a building; esp., a building of some size or magnificence; an edifice.
v. t.
To make a solemn declaration or affirmation of; to proclaim; to display; as, to protest one's loyalty.
n.
The act of building; the practice of erecting buildings; construction.
a.
Of or related to protein; albuminous; proteid.
n.
Arrangement of parts, of organs, or of constituent particles, in a substance or body; as, the structure of a rock or a mineral; the structure of a sentence.
a.
Exceedingly variable; readily assuming different shapes or forms; as, an amoeba is a protean animalcule.
n.
A name given to any one of several yellow or scarlet dyestuffs of artificial production and complex structure. In general they are diazo and sulphonic acid derivatives of benzene and naphthol.
a.
Having a definite organic structure; showing differentiation of parts.
n.
Manner of organization; the arrangement of the different tissues or parts of animal and vegetable organisms; as, organic structure, or the structure of animals and plants; cellular structure.
v.
A solemn declaration of opinion, commonly a formal objection against some act; especially, a formal and solemn declaration, in writing, of dissent from the proceedings of a legislative body; as, the protest of lords in Parliament.