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Known RNA transcripts of DNA whose function is unclear
Transcripts of unknown function (TUFs) is the name that has been suggested for known RNA transcripts of DNA whose function is unclear. Most are probably
Transcript of unknown function
Transcript_of_unknown_function
Topics referred to by the same term
to: Tenant Union Federation Transformer utilization factor Transcript of unknown function The Ultimate Fighter, a reality television series The Update
TUF
Conversion of a gene's sequence into a mature gene product or products
profiling tool Transcriptional bursting Transcriptional noise Transcript of unknown function Brody L. "Gene Expression". National Human Genome Research Institute
Gene_expression
certain non-coding RNAs. transcript of unknown function (TUF) Any RNA transcript whose function is unclear. Such transcripts may include functional non-coding
Glossary of cellular and molecular biology (M–Z)
Glossary_of_cellular_and_molecular_biology_(M–Z)
ELAVL3 Transcript of unknown function Bourdeau V, Ferbeyre G, Pageau M, Paquin B, Cedergren R (November 1999). "The distribution of RNA motifs in natural
Ribonomics
Effort to determine the DNA sequence of the chimpanzee genome
severe neurological defects in human children. WASH2P. Several transcripts of unknown function corresponding to this region have been isolated. This region
Chimpanzee_genome_project
Non-protein coding transcripts longer than 200 nucleotides
do not have a biologically relevant function because they are transcripts of junk DNA. Long non-coding transcripts are found in many species. Large-scale
Long_non-coding_RNA
Human protein
consists of 182 amino acids with a molecular weight of 20 kDa and an isoelectric point of 5 pI. The protein contains a domain of unknown function (DUF4660)
C1orf52
Class of ribonucleic acid that is not translated into proteins
thousands of non-coding transcripts. Many of the newly identified ncRNAs have unknown functions, if any. There is no consensus on how much of non-coding transcription
Non-coding_RNA
Human gene
a total of 8 exons with an upstream in-frame stop codon located within the first exon, a disordered region, and a domain of unknown function. The mRNA
UPF0602
for a protein of unknown function. KIAA0090 has two aliases OTTHUMP00000002581 and RP1-43E13.1. The gene codes for multiple transcript variants which
KIAA0090
Protein encoding gene in mammals
it as a region of functional significance. The region downstream of the transmembrane region is considered a domain of unknown function (DUF) within pfam
C2orf74
types of RNA, grouped by role. Abbreviations for the different types of RNA are listed and explained. List of cis-regulatory RNA elements RNA: Types of RNA
List_of_RNAs
Protein found in humans
by the CCDC138 gene. The exact function of CCDC138 is unknown. The CCDC138 gene can be found at the positive strand of chromosome 2. The CCDC138 gene
CCDC138
Protein-coding gene in the species Homo sapiens
human mRNA transcript is 2527 base pairs and the final protein product is 756 amino acids. While the exact function of this protein remains unknown, due to
SH3D21
RNA family
larger transcript into a shorter RNA that roughly corresponds to the conserved, ~610-nucleotide structure. Genes encoding a protein class of unknown function
OLE_RNA
Protein found in humans
significant expression in smooth muscle tissue. There is a domain of unknown function. The c4orf54 protein is myristylated with over 20 predicted sites
Chromosome 4 open reading frame 54
Chromosome_4_open_reading_frame_54
1979 An unknown contingency plan (which some[who?] believe was Rex 84) was publicly mentioned during the Iran-Contra Hearings in 1987. Transcripts from the
United States federal government continuity of operations
United_States_federal_government_continuity_of_operations
Human protein
KIAA1143-like Family, and contains DUF4604 domain of unknown function. KIAA1143 has a predicted function of cell structure/mobility by encoding heavy neurofilament
KIAA1143
Protein found in humans
encoded by the CCDC166 gene. Its function is currently unknown. It contains a coiled-coil domain, hence the current origin of its name. It is primarily expressed
Coiled-coil domain containing 166
Coiled-coil_domain_containing_166
Protein-coding gene in the species Homo sapiens
conserved regions among distant orthologs, internal repeats, domains of unknown function (DUF regions), signal peptides, transmembrane regions, poly-A sites
TMEM273
Different products from the same gene
modification process that produces mRNA transcript isoforms, while isoforms can result in different functions, activities, or expression patterns . The
Isoform
Biochemical changes to RNA
the studies have been focused on viral transcripts of mammalian viruses. Mammalian viral transcripts must function in a mammalian cell, so they must acquire
Epitranscriptome
Canadian man raised as a girl (1965–2004)
York Times. ISSN 0362-4331. Retrieved 14 March 2022. "Sex: Unknown". Nova. 2001. PBS. Transcript. Dreger, Alice D.; Herndon, April M. (1 April 2009). "Progress
David_Reimer
12001. In particular, this conserved domain contains the domain of unknown function DUF3496 which is about 110 amino acids long, functionally uncharacterized
Uncharacterized LOC644249 gene
Uncharacterized_LOC644249_gene
RNA family
intronic regions of the BART (Bam HI-A region rightward transcript) gene whose function is unknown. mir-BART2 is thought to target the virally encoded DNA
Mir-BART2 microRNA precursor family
Mir-BART2_microRNA_precursor_family
Extracellular protein in Homo sapiens
that contains a domain of unknown function, DUF4596, towards the C terminus of the protein. The function of PRP36 is unknown, but high gene expression
PRP36
RNA family
(Bam HI-A region rightward transcript) gene whose function is unknown. The mature sequence is excised from the 5' arm of the hairpin. Qureshi A, Thakur
Mir-BART1 microRNA precursor family
Mir-BART1_microRNA_precursor_family
Protein-coding gene in the species Homo sapiens
human version of UPF0739 contains 269 amino acids and weighs 29430 Da. Amino acids 19 to 269 are part of a domain of unknown function known as DUF4504
C1orf74
Human gene
relatively higher expression in the brain and thymus. Although its function remains unknown, predicted nuclear localization and expression patterns suggest
FAM200B
Protein-coding gene in the species Homo sapiens
the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist
EPS8L3
2010 aviation accident in Russia
Interior Ministry published a transcript from the cockpit voice recorder of the crashed Tu-154M.[citation needed] The transcript confirmed earlier reports
Smolensk_air_disaster
Protein-coding gene in humans
create five transcript variants that vary from 4,720 base pairs (bp) to 2,144 bp in the mature mRNA. The longest and most complete transcript of the gene
BEND2
Mammalian protein found in Homo sapiens
indicative of a domain known as DUF2373 ("domain of unknown function 2373"), found in isoforms a, b, and c. C7orf50 has a predicted molecular weight (Mw) of 22
C7orf50
concern Tesla's suite of advanced driver assistance system (ADAS) functions, marketed as of December 2025[update] as "Full Self-Driving (Supervised)" ("FSD")
List of predictions for autonomous Tesla vehicles by Elon Musk
List_of_predictions_for_autonomous_Tesla_vehicles_by_Elon_Musk
Software design pattern
created that implements all of the appropriate specializations of the virtual function. The visitor takes the instance reference as input, and implements
Visitor_pattern
Protein-coding gene in the species Homo sapiens
has 5 transcript isoforms, C20orf27 transcript variant 1, C20orf27 transcript variant 2, C20orf27 transcript variant 3, and C20orf27 transcript variant
C20orf27
Second season of Avatar: The Last Airbender animation series
with "Avatar" Program Creators — Page 3". Animation Insider (Interview: Transcript). Interviewed by Aaron H. Bynum. Archived from the original on August
Avatar: The Last Airbender season 2
Avatar:_The_Last_Airbender_season_2
RNA family
also possible that COG3610-DE function in trans, and it is a coincidence that they are located downstream of gene transcripts. If COG3610-DE RNAs are cis-regulatory
COG3610-DE_RNA_motif
Blood-clotting protein
form Xa. The factor VIII gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates
Factor_VIII
Study of causation, or origination
(-logía) 'study of'). More completely, etiology is the study of the causes, origins, or reasons behind the way that things are, or the way they function, or it
Etiology
Uncharacterized gene
length. A large domain of unknown function, DUF4518, encompasses majority of the C3orf38 protein. This domain is a part of the protein family pfam15008
C3orf38
Class of peptides
transcript it reported a higher level of ribosome drop-off after one 2A sequence than after two 2As combined, which is at odds with a linear model of
2A_peptides
1992 single by the Cure
SPIN. 12 February 2021. Retrieved January 23, 2022. "The Cure Interview Transcript - discogs.com". "The Cure's Robert Smith interview - Part Two". femalefirst
Friday_I'm_in_Love
Protein-coding gene in the species Homo sapiens
of varying lengths. There are 23 different transcript variants in GPATCH2L Homo sapiens. The most common is transcript variant 1 and each transcript variant
GPATCH2L
Genetic sequence structure within eukaryote chromosomes
during transcription, and so does not become part of the 3' UTR. Its function, if any, is unknown. Introns are intervening sequences between the exons
Eukaryotic chromosome fine structure
Eukaryotic_chromosome_fine_structure
Protein found in humans
domains crucial for protein function. Domain of Unknown Function 607 (DUF607): The function of this domain is largely unknown, although it may serve as
MCUB
Protein-coding gene in the species Homo sapiens
Beach, and WD40 repeats. DUF4704 is a domain of unknown function. While the function of this domain is unknown, it is conserved within neurobeachin proteins
NBEAL1
Malicious software
of Self-Reproducing Automata", Part 1: Transcripts of lectures given at the University of Illinois, December 1949, Editor: A. W. Burks, University of
Malware
Protein-coding gene in the species Homo sapiens
is the domain of unknown function 3808 (DUF3808), spanning the majority of the protein. The gene for TTC39B is located on the short arm of the ninth chromosome
Tetratricopeptide repeat protein 39B
Tetratricopeptide_repeat_protein_39B
Protein-coding gene in the species Homo sapiens
the function of this gene is unknown, various data have revealed that it is expressed at high levels in various cancerous tissues. Underexpression of this
METTL26
Basic emotion induced by a perceived threat
Archives Episode 80 Transcript: The Librarian". The Magnus Archives Transcripts Archive Archive A. "The Magnus Archives Episode 35 Transcript: Hive". The Magnus
Fear
Human protein
mdm2 and, therefore, loss of p53 function and cell cycle control. The equivalent in mice is p19ARF. The p14ARF transcript was first identified in humans
P14arf
Human gene
conserved human gene found on the plus strand of the short arm of the X chromosome. The exact function of the gene is poorly understood, but the polysaccharide
PBDC1
President of the United States from 2001 to 2009
pulls out of Saudi Arabia". BBC News. April 29, 2003. Archived from the original on May 21, 2019. Retrieved February 7, 2022. "Transcript of President
George_W._Bush
Set of all modifications of viral transcripts
affect the sequence of the transcript, but rather have consequences on subsequent structures and functions. The discovery of mRNA modifications dates back
Viral_epitranscriptome
Protein-coding gene in the species Homo sapiens
in length, has a molecular weight of 51.6 kDa and an isoelectric point of 9.7 in humans. A domain of unknown function (DUF3754) is present within which
TMEM143
transcriptional variants of TMEM202 mRNA. 'Y' indicates the presence of the exon in the specific transcript variant, whereas 'X' denotes absence of the exon. '*'
TMEM202
US state criminal case against president
Money Trial—May 30, 2024 on C-SPAN Closing Arguments (or Summations), "Transcript of Trump Manhattan Trial, May 28, 2024", via The New York Times Jury Instructions
Prosecution of Donald Trump in New York
Prosecution_of_Donald_Trump_in_New_York
Legal term
Taxation of costs is a ministerial function performed by a court upon the resolution of case. It involves entering the various costs and their amounts
Taxation_of_costs
Protein-coding gene in the species Homo sapiens
domain of unknown function (DUF4566) present in all three variants and spans positions 1–226 on the main transcript. The molecular weight of C6orf62
C6orf62
Human protein encoding gene
reside within the nucleus, cytosol, and plasma membrane of cells. The function of C2orf72 is unknown, but it is predicted to be involved in very-low-density
C2orf72
German war criminal (1906–1967)
Years later, Clay stated: There was absolutely no evidence in the trial transcript, other than she was a rather loathsome creature, that would support the
Ilse_Koch
Protein-coding gene in the species Homo sapiens
time. The domain of unknown function 3342 is conserved in all orthologs. It is the highest conserved region of the protein. Conservation of this domain was
KIAA1841
Allied trial of Nazis after World War II
Liberation of a Concentration Camp. Toronto: University of Toronto Press. ISBN 9781442615700. "Transcript of the Official Shorthand Notes of 'The Trial of Josef
Belsen_trials
uses a Sankey diagram to visualize search findings, and displays "snippets" of text from relevant scientific literature. EmBiology was originally launched
EMBiology
Set of all RNA molecules in one cell or a population of cells
set of all RNA molecules (transcripts) in a cell or a population of cells. It includes all of the functional RNA molecules and all other transcripts that
Transcriptome
Messaging and VoIP service owned by Meta
Malik, Aisha (November 21, 2024). "WhatsApp rolls out voice message transcripts". TechCrunch. Archived from the original on December 19, 2024. Retrieved
British-American mass murderer and terrorist (1991–2014)
Angeles Times. The Manifesto of Elliot Rodger May 25, 2014, Retrieved February 22, 2026 – via The New York Times. Transcript of Elliot Rodger's Retribution
Elliot_Rodger
Fantasy role-playing video game
series of games and books. The earliest editions of the game used a series title of Tales of the Unknown, but this title was dropped for later ports of The
The Bard's Tale (1985 video game)
The_Bard's_Tale_(1985_video_game)
Former office building in Manhattan, New York
accommodate the building. The 5th floor functioned as a structural diaphragm, providing lateral stability and the distribution of loads between the new and old
7 World Trade Center (1987–2001)
7_World_Trade_Center_(1987–2001)
Protein found in humans
majority of the protein and is highly conserved among orthologs. The final domain is a Domain of unknown function (DUF3504) found near the end of the protein
QRICH1
Protein-coding gene in the species Homo sapiens
C22orf31 mRNA transcript has an upstream in-frame stop codon, while the protein has a domain of unknown function (DUF4662) spanning the majority of the protein-coding
C22orf31
Queen of the United Kingdom since 2022
Archived 1 July 2010 at the Wayback Machine, 18 December 1989, phone transcript, Phone Phreaking Brandreth 2007, p. 275. Brandreth 2007, pp. 274–276.
Queen_Camilla
Cellular process
coordinated function of over 200 proteins in the synthesis and processing of the three prokaryotic or four eukaryotic rRNAs, as well as assembly of those rRNAs
Ribosome_biogenesis
Region of DNA encouraging transcription
sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may
Promoter_(genetics)
nucleus. It has a calculated molecular weight of 23.29 kDa. It also contains DUF2475, a protein of unknown function from amino acid 19–85. The FAM166C protein
FAM166C
Protein-coding gene in the species Homo sapiens
bone), the immune system, and nervous system. Eleven different mRNA transcript variants of TMEM33 exist, 9 alternatively spliced variants and 2 unspliced forms
TMEM33
Agreement ending the American Revolutionary War
War History of the United States (1776–1789) List of United States treaties Ratification Day (United States) Transcript of the Treaty of Paris Miller
Treaty_of_Paris_(1783)
President of El Salvador since 2019
Retrieved 25 March 2024. Bergengruen, Vera (29 August 2024). "Read the Full Transcript of President Nayib Bukele's Interview with TIME". Time. San Salvador, El
Nayib_Bukele
1885 novel by Mark Twain
Boston Transcript: The Concord (Mass.) Public Library committee has decided to exclude Mark Twain's latest book from the library. One member of the committee
Adventures of Huckleberry Finn
Adventures_of_Huckleberry_Finn
2008 film by Darren Aronofsky
"History of 16mm Film". ScanCafe. August 4, 2020. Retrieved March 17, 2022. "'The Wrestler' Director Darren Aronofsky" downloaded interview/no transcript Archived
The_Wrestler_(2008_film)
President of the United States from 2021 to 2025
it,' Biden said in February 2002. Russert, Tim (April 29, 2007). "MTP Transcript for April 29, 2007". Meet the Press. NBC News. p. 2. Archived from the
Joe_Biden
2025 mobile operating system
braille files, and app navigation. It also provides real-time conversation transcripts on the braille display. Head Tracking allows the user to control the
IOS_26
Country in West Asia
Post. Retrieved 20 March 2012. ElBaradei, Mohamed (27 July 2004). "Transcript of the Director General's Interview with Al-Ahram News". International
Israel
Supertall skyscraper in Shanghai, China
refer to the building as "the bottle opener". Metal replicas of the building that function as actual bottle openers are sold in the tower's gift shop.
Shanghai World Financial Center
Shanghai_World_Financial_Center
U.S. presidential administration since 2025
a Ballroom Dinner. The White House. October 15, 2025 – via YouTube. "TRANSCRIPT: President Trump Hosts a Ballroom Dinner at the White House, 10.15.25"
Second presidency of Donald Trump
Second_presidency_of_Donald_Trump
Control of gene expression at the RNA level, between transcription and translation
Post-transcriptional regulation significantly affects transcript level, function, structure and expression of final proteins. Importance Post-transcriptional
Post-transcriptional regulation
Post-transcriptional_regulation
Protein-coding gene in humans
protein of 377 amino acid residues. ERGIC2 protein is also known as PTX1, CDA14 or Erv41. The biological function of ERGIC2 protein is unknown, although
ERGIC2
Fictional character, The Bear TV series
Retrieved 2025-10-01. "The Bear - S05E08 - The Original Beef of Chicagoland - Transcript". Scraps from the loft. July 3, 2026. Retrieved 2026-07-07. Bradley
Carmy_Berzatto
Enzyme in the human body
(abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the human body. In
CYP1A2
Ancient lighthouse in Egypt
Season 24. Episode 14. November 18, 1997. PBS. Transcript. Retrieved March 5, 2012. "Sunken Ruins of Alexandria Will Be World's First Underwater Museum"
Lighthouse_of_Alexandria
"Netanyahu transcript: 'We have to be more powerful than the barbarians, or they will crash our gates, destroy our societies'". The Times of Israel. Retrieved
Timeline_of_the_2026_Iran_war
American mathematician and Nobel Laureate (1928–2015)
diffeomorphic to the zero set of some collection of smooth functions on Euclidean space. In his work, Nash proved that those smooth functions can be taken to be
John_Forbes_Nash_Jr.
Protein found in humans
on the minus strand of chromosome 2 and encodes three protein isoforms. All isoforms of CCDC121 contain a domain of unknown function referred to as DUF4515
CCDC121
Study of RNA transcripts
non-coding RNAs perform additional diverse functions. A transcriptome captures a snapshot in time of the total transcripts present in a cell. Transcriptomics
Transcriptomics_technologies
Protein-coding gene in the species Homo sapiens
function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different
LAIR2
RNA family
mutations in the RNA transcript made by RNAse MRP, whereas around 30 distinct mutations have been identified in the promoter region of the RNAse MRP gene
RNase_MRP
English rock musician (born 1959)
The Cure's wounds", Folha de S.Paulo (Brazil), 10 January 2000. English transcript at Chainofflowers.com. "The Cure proclaimed Godlike Geniuses by Tim Burton"
Robert_Smith_(musician)
Protein-coding gene in the species Homo sapiens
C16orf71 has one identified domain of unknown function, DUF4701, that is conserved in all mammals and some species of reptiles and birds. DUF4701 spans
C16orf71
TRANSCRIPT OF-UNKNOWN-FUNCTION
TRANSCRIPT OF-UNKNOWN-FUNCTION
Boy/Male
Tamil
Deshayan | தேஷாயநÂ
Unknown
Deshayan | தேஷாயநÂ
Girl/Female
Indian, Tamil
Unknown Species; Not Known
Girl/Female
Tamil
Satakshi | ஸதாகà¯à®·à¯€
Unknown
Satakshi | ஸதாகà¯à®·à¯€
Girl/Female
Tamil
Unknown
Boy/Male
Unknown
Origin unknown.
Girl/Female
Indian
Unknown
Boy/Male
Tamil
Aparichit | அபரிசிதÂ
Unknown
Aparichit | அபரிசிதÂ
Boy/Male
Tamil
Unknown
Boy/Male
Indian
Unknown
Boy/Male
Tamil
Unknown
Girl/Female
Muslim
Unknown
Boy/Male
Unknown
Origin unknown.
Girl/Female
Indian
Unknown
Girl/Female
Unknown
Origin unknown.
Boy/Male
Hindu
Unknown
Girl/Female
Indian
Unknown
Girl/Female
Hindu
Unknown
Boy/Male
Shakespearean
King Henry IV, Part 1' Earl of March. Scroop.
Girl/Female
Tamil
Amaanya | அமாநà¯à®¯à®¾Â
Unknown
Amaanya | அமாநà¯à®¯à®¾Â
Boy/Male
Indian
Unknown
TRANSCRIPT OF-UNKNOWN-FUNCTION
TRANSCRIPT OF-UNKNOWN-FUNCTION
Girl/Female
American, Arabic, Australian, British, Chinese, Christian, Dutch, English, French, German, Greek, Hebrew, Irish, Polish, Swedish
Lady; Mistress of the House; Mistress; Dedicated to Mars
Boy/Male
Australian, Celtic, Christian, Gaelic, Irish
Handsome; Fair; Little White One
Boy/Male
English French
Abbreviation of Dionysius.
Boy/Male
Spanish
Victor.
Boy/Male
Afghan, Arabic, Australian, French, Hindu, Indian, Iranian, Marathi, Muslim, Parsi, Sindhi
Great; Noble; Gratifying; Excellent; Illustrious; Glorious
Male
Yiddish
(ק×זמיר) Yiddish form of Polish Kazimierz, KUZMIR means "commands peace."
Surname or Lastname
English
English : variant of Burrows.
Boy/Male
Tamil
Guru Gugan | கà¯à®°à¯ கà¯à®•à®¨Â
Master of tribes
Boy/Male
Muslim
Goodness, Excellence
Girl/Female
Australian, French, Greek
Friendship; Help
TRANSCRIPT OF-UNKNOWN-FUNCTION
TRANSCRIPT OF-UNKNOWN-FUNCTION
TRANSCRIPT OF-UNKNOWN-FUNCTION
TRANSCRIPT OF-UNKNOWN-FUNCTION
TRANSCRIPT OF-UNKNOWN-FUNCTION
v. t.
To write over again, or in the same words; to copy; as, to transcribe Livy or Tacitus; to transcribe a letter.
a.
Not known; not apprehended.
p. pr. & vb. n.
of Transcribe
n.
A copy of any kind; an imitation.
a.
Unknowing; also, unknown; unmeaning.
n.
A copy; a transcript.
n.
That which has been transcribed; a writing or composition consisting of the same words as the original; a written copy.
a.
Unknown.
a.
Not known; unknown.
imp. & p. p.
of Transcribe
n.
A copy; a transcript.
v. t.
To fail of knowing; to be ignorant of.
v. t.
To copy; to transcribe.
n.
A written version of what was said orally; as, a transcript of a trial.
v. t.
To copy; to transcribe; to make an attested copy or transcript of, under seal, as of a record.
a.
Fully known; generally known or acknowledged.
a.
Not known; unknown.
prep.
Denoting the material of which anything is composed, or that which it contains; as, a throne of gold; a sword of steel; a wreath of mist; a cup of water.
n.
A copy or transcript.
n.
A copy or transcript.