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Topics referred to by the same term
Look up uncouple, uncoupler, or uncoupling in Wiktionary, the free dictionary. Uncoupling or uncouple may refer to: Uncoupling (neuropsychopharmacology)
Uncoupling
Type of divorce
is conscious uncoupling?". The Guardian. Retrieved 2025-03-09. Elle.com, Natalie Matthews. "What Gwyneth Paltrow's 'Conscious Uncoupling' really means"
Conscious_uncoupling
Type of biological molecule
An uncoupler or uncoupling agent is a molecule that disrupts oxidative phosphorylation in prokaryotes and mitochondria or photophosphorylation in chloroplasts
Uncoupler
American romantic comedy television series
Uncoupled is an American romantic comedy television series created by Darren Star and Jeffrey Richman that premiered on Netflix on July 29, 2022. The
Uncoupled
Concept in neuropsychopharmacology
morphine can lead to uncoupling of opioid receptors, reducing their responsiveness over time. Mize, Amy L; Alpher, Richard H. "Rapid uncoupling of serotonin-1A
Uncoupling (neuropsychopharmacology)
Uncoupling_(neuropsychopharmacology)
Mitochondrial protein
An uncoupling protein (UCP) is a mitochondrial inner membrane protein that is a regulated proton channel or transporter. An uncoupling protein is thus
Uncoupling_protein
Termination of an intimate relationship
and his wife explain conscious uncoupling when she first made the news of her divorce public. "A conscious uncoupling is the ability to understand that
Breakup
Protein-coding gene in the species Homo sapiens
1999). "Functional organization of the human uncoupling protein-2 gene, and juxtaposition to the uncoupling protein-3 gene". Biochemical and Biophysical
UCP2
Mammalian protein found in Homo sapiens
Thermogenin (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1) is a mitochondrial carrier protein found in
Thermogenin
American television writer and producer (born 1961)
(1998–2004), Younger (2015–2021), Emily in Paris (2020–present), and Uncoupled (2022). Darren Star was born to a Jewish family in Potomac, Maryland.
Darren_Star
Protein-coding gene in the species Homo sapiens
conformation distinct from other uncoupling proteins, suggesting potential functional or regulatory differences. Mitochondrial uncoupling proteins (UCPs) are part
Mitochondrial uncoupling protein 4
Mitochondrial_uncoupling_protein_4
Automatic railway coupling
coupling of air pipes (partial uncoupling with a lever) Level 3: Level 2 plus automatic coupling of power cables (allows uncoupling with switch) Level 4: Level
Digital_automatic_coupling
American writer (born 1959)
1959) is an American novelist, known for The Wife, The Ten-Year Nap, The Uncoupling, The Interestings, and The Female Persuasion. She is a co-director of
Meg_Wolitzer
Chemical compound
pesticide and herbicide. In humans, DNP causes dose-dependent mitochondrial uncoupling, causing the rapid loss of ATP as heat and leading to uncontrolled hyperthermia—up
2,4-Dinitrophenol
American actor
in The Boys in the Band, Troy on The Other Two, and Colin McKenna on Uncoupled. Charles Curtis Watkins III was born in Kansas City, Kansas. He graduated
Tuc_Watkins
American actor
Rey 2018 Vida Jackson Episode 4 2019 Goliath Rob Episode: "Conscious Uncoupling" 2022 Boo, Bitch Mo 3 episodes 2022 American Horror Stories Chaz Episode:
Anthony_De_La_Torre
1984 musical by Andrew Lloyd Webber
opponents. Pearl is distracted by Rusty's presence, causing Greaseball to uncouple her at full speed. Rusty diverts from the race course just in time to save
Starlight_Express
When a receptor decreases its response to an agonist at high concentration
still being characterized, there are currently four known mechanisms: uncoupling of receptors from associated G proteins, endocytosis, degradation, and
Homologous_desensitization
Protein-coding gene in the species Homo sapiens
membrane. Uncoupling proteins transfer anions from the inner mitochondrial membrane to the outer mitochondrial membrane, thereby separating (or uncoupling) oxidative
UCP3
Fandos, Nicholas; Oreskes, Benjamin (November 14, 2025). "The Strategic Uncoupling of Zohran Mamdani and Brad Lander". The New York Times. Retrieved November
2026 United States House of Representatives elections in New York
2026_United_States_House_of_Representatives_elections_in_New_York
Personality disorder
variance with the five initial ICD-11 domains and cannot be factorially uncoupled from negative affectivity. Furthermore, it adds nothing to the prediction
Borderline personality disorder
Borderline_personality_disorder
American actor
married to Bonnie Wheeler. He also played Josh on the Netflix comedy series Uncoupled opposite Neil Patrick Harris. In 2021, he starred as Dimitri Von Leuschner
Peter_Porte
American politician (born 1969)
Fandos, Nicholas; Benjamin, Oreskes (November 14, 2025). "The Strategic Uncoupling of Zohran Mamdani and Brad Lander". The New York Times. Retrieved November
Brad_Lander
Type of physics demonstration
elementary physics demonstration and kinetic art comprising a number of uncoupled simple pendulums with monotonically increasing lengths. As the pendulums
Pendulum_wave
Chemical compound
that acts as an uncoupling agent. 2,4-Dinitrophenol Perfluorotriethylcarbinol SF-6847 Ilivicky, J; Casida, JE (June 1969). "Uncoupling action of 2,4-dinitrophenols
TTFB_(chemical)
Train crew member
Directing the train's movement while operating in reverse Coupling or uncoupling cars Assisting with setting out or picking up rolling stock Some rapid-transit
Conductor_(train_crew)
Mechanism for connecting rolling stock in a train
Remote uncoupling is possible by using a sprung ramp between the rails. The design of the hooks ensures that the couplings will not uncouple under tension
Railway_coupling
Canadian television series
Filippo Jenn Engels April 8, 2025 (2025-04-08) 481785-6 7 7 "Conscious Uncoupling" Aleysa Young Anita Kapila April 15, 2025 (2025-04-15) 481785-7 8 8 "Family
Small_Achievable_Goals
Season of television series
Gribble. This episode was dedicated in memory of him. 267 8 "Kahn-scious Uncoupling" Kyounghee Lim Jeremy Hsu August 4, 2025 (2025-08-04) EABE09 Hank finds
King_of_the_Hill_season_14
Chemical compound
Charles L; Kirwan, John P (7 July 2020). "BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control". EMBO Molecular
BAM15
Chemical compound
which disrupt mitochondrial transmembrane electrochemical gradients. This uncoupling leads to a fast drop in ATP production and, consequently, a prompt activation
XCT-790
2024 song by Ariana Grande
Although there's a gently retro disco-funk sound to "Bye", its conscious uncoupling vibe can't quite take the song into pose-striking "I Will Survive" territory
Bye_(Ariana_Grande_song)
Genus of flowering plants
compared to the plant at times due to its typical features of the uncoupling protein. Uncoupling protein plays a role in the production of energy to become heat
Helicodiceros
Chemical compound
epoxide. Perfluorination affords perfluorotriethylcarbinol, a powerful uncoupling agent. 3-ethyl-3-pentanol at chemsynthesis.com Sager, W. F. (October 1956)
3-Ethyl-3-pentanol
2025 Japanese film by Shinji Higuchi
branch where they can safely explode while using timed track switches to uncouple the final two cars. Matsumoto leaves the train running and joins the remaining
Bullet_Train_Explosion
Unusual discomfort when in a cool environment
vasoconstriction. There may also be differences in people in the expression of uncoupling proteins, thus affecting their amount of thermogenesis. Psychology may
Cold_sensitivity
English singer-songwriter (born 1977)
March 2014, Martin and Paltrow announced their separation as a "conscious uncoupling" after ten years of marriage. Paltrow filed for divorce in April 2015
Chris_Martin
Filipino actor (born 1990)
Tadhana Butchok Wagas Rocky 2019 The Orbiters Pol Manilennials Romeo Uncoupling Kurt 2020 I Am U Tristan 2020–2021 Paano ang Pasko? / Paano ang Pangako
Cedrick_Juan
Plants that can produce heat
of cellular respiration called thermogenesis. Alternative oxidase and uncoupling proteins similar to those found in mammals enable the process, which is
Thermogenic_plant
Process of heat production within organisms
has a unique uncoupling protein (thermogenin, also known as uncoupling protein 1) that allows for the synthesis of ATP to be uncoupled from the production
Thermogenesis
1976 British electric trains
include electrical and pneumatic connections allowing the coupling and uncoupling of units to be performed unassisted by the driver whilst in the cab. The
British_Rail_Class_313
Line of 35mm SLR cameras by Zeiss Ikon
designed by Albrecht Tronnier, Joachim Eggert, and Fritz Uberhagen, and an uncoupled through-the-lens (TTL) metering eye-level pentaprism, which also was offered
Icarex
American actress and singer (born 1968)
(Disney, 2011), Dr. Ken (ABC, 2015–2017), Outmatched (Fox, 2020) and Uncoupled (Netflix, 2022). Tisha Campbell was born in Oklahoma City, Oklahoma and
Tisha_Campbell
35mm rangefinder camera
Rangefinder Image 1954–58 B No No BL Yes No BR No Yes 1959–68 C No No CD Yes, uncoupled selenium No CL Yes, coupled selenium No CLR Yes, coupled selenium Yes
Voigtländer_Vito
Filipino actress (born 1992)
Joanna 2015 Second Chances Yvette 2018 The Blood Sisters Sahara 2019 Uncoupling 2020 Ipaglaban Mo! Carmina Episode: "Tukso" Pamilya Ko Christina "Tina"
Nathalie_Hart
Metabolic pathway
In brown adipose tissue, regulated proton channels called uncoupling proteins can uncouple respiration from ATP synthesis. This rapid respiration produces
Oxidative_phosphorylation
American sociologist
relationship breakups. Controlling Unlawful Organizational Behavior (1983). Uncoupling. Turning Points in Intimate Relationships (1986), Oxford University Press
Diane_Vaughan
American comedian and actress (born 1970)
[@SarahKSilverman] (February 5, 2018). "The great @michaelsheen & I consciously uncoupled over Christmas" (Tweet). Archived from the original on February 5, 2018
Sarah_Silverman
American sportswriter and host (born 1985)
relationship ended in 2025 as part of what Torre described as a "conscious uncoupling" due to the reputation of sports gambling companies. In September 2025
Pablo_S._Torre
Topics referred to by the same term
(disambiguation) Decoupling (disambiguation) Odd Couple (disambiguation) Uncouple (disambiguation) Coupled, an American dating game show Thermocouple, a
Couple
American actor (born 1985)
Catherine: A Royal Romance. He also plays Luke on the Netflix comedy series Uncoupled opposite Neil Patrick Harris. Amboyer was born in Detroit to Claudia and
Dan_Amboyer
Locomotive wheel arrangement
powered but uncoupled driving wheels on two axles, and no trailing wheels. Some authorities place brackets around the duplicated but uncoupled wheels, creating
0-2-2-0
Chemical compound
to mammals due to it being rapidly metabolised to a compound without uncoupling activity. It was first described in 1992 and was developed by researchers
Fluazinam
structure of the COX enzyme. However, other effects of aspirin, such as uncoupling oxidative phosphorylation in mitochondria, and the modulation of signaling
Mechanism of action of aspirin
Mechanism_of_action_of_aspirin
Chemical compound
inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes by uncoupling mitochondrial oxidative phosphorylation". Endocrinology. 143 (10): 3884–3896
Rottlerin
Chemical compound
domestic animals such as cattle, sheep, and goats. It mainly acts by uncoupling of oxidative phosphorylation in flukes. Along with niclosamide, another
Oxyclozanide
Organism that maintains body temperature largely by heat from internal bodily functions
Examples include special-function muscular exertion such as shivering, and uncoupled oxidative metabolism, such as within brown adipose tissue. Only birds
Endotherm
Japanese high-speed railway line
Hayabusa-Komachi 21 train, composed of the H5 and E6 series Shinkansen, uncoupled while travelling between Ueno and Omiya stations at around 60 km/h . Both
Tōhoku_Shinkansen
Automatic railway coupling
German) Coupling process of a Scharfenberg coupler (Labels in German) Uncoupling process of a Scharfenberg coupler (Labels in German) Rail equipment manufacturers
Scharfenberg_coupler
Actress
Beth Kennedy 20 episodes 2016 Doctors Willow Cobb Episode: "A Conscious Uncoupling" Camping Catherine Mini-series; Episode 5 2018 Silent Witness Mel McMorris
Grace_Hogg-Robinson
Indian actor, model and entrepreneur
Jayesh Takhur 2010 Toh Baat Pakki! Yuvvraaj Saxena 2011 Hostel Karan 2012 Uncoupled Shaan Short film 2013 Season's Greetings Sam 2014 Jai Ho Harjeet 2016
Vatsal_Sheth
American actor (born 1955)
Number One" 2020–2024 Power Book II: Ghost Oliver Simmons 10 episodes 2022 Uncoupled Henry 1 episode 2023 The Marvelous Mrs. Maisel David Weston Episode: "The
Bruce_Altman
Film camera
is quite unusual amongst Japanese rangefinder cameras of this era. The uncoupled meter gives light readings in exposure values within the viewfinder which
Olympus_35SP
Animal species that can maintain a body temperature higher than their environment
dissipation of the mitochondrial gradient as heat via an uncoupling protein, thereby "uncoupling" the gradient from its usual function of driving ATP production
Warm-blooded
uncoupling the gene conversion network, thereby allowing new genes to evolve. The shorter Alu or SINE repetitive DNA are specialized for uncoupling intrachromosomal
Interspersed_repeat
Fastest rail-based transport systems
the TGV, the trailers had two conventional bogies per car, and could be uncoupled, allowing the train to be lengthened or shortened. This introduction was
High-speed_rail
Railway station in Goslar, Germany
in platform 1, while platform 2 is used at about the same time for the uncoupling of the portions running towards the Harz. Platform 3 has not been modified
Vienenburg_station
Model railroad scale of 1:87
clearance necessary. Most couplers provide pre-uncoupling, whereby a train may reverse over a raised uncoupler and some time later change direction leaving
HO_scale
Chemical compound
effective as an insecticide. It acts as a prodrug to the mitochondrial uncoupler (IRAC group 13) perfluorooctanesulfonamide. Annual production increased
Sulfluramid
Group of chemical compounds
mitochondrial uncoupling. This process is due to facilitated diffusion of protons into the mitochondrial matrix through an uncoupling protein such as
Oligomycin
Chemical compound
in C. elegans models, suggesting a degree of hormesis. CCCP causes an uncoupling of the proton gradient that is established during the normal activity
Carbonyl cyanide m-chlorophenyl hydrazone
Carbonyl_cyanide_m-chlorophenyl_hydrazone
Trailer vehicle without a front axle
with landing gear (legs which can be lowered) to support it when it is uncoupled. Many semi-trailers have wheels that are capable of being totally dismounted
Semi-trailer
Clutch type
limit the torque by slipping (as in a friction plate slip-clutch), or uncouple the load entirely (as in a shear pin). The action of a torque limiter is
Torque_limiter
wheel on a steam locomotive is a wheel that is not driven; i.e., it is uncoupled and can run freely, unlike a coupled or driving wheel. It is also described
Carrying_wheel
Philosophical school of thought
religious narrative in favor of human-generated knowledge. This ultimately uncoupled the fate of humans from the divine will, prompting social and political
Humanism
Type of rolling stock used on the London Underground Piccadilly line
comprising 196 driving motor (DM) cars, 175 trailer (T) cars, and 154 uncoupling non-driving motor (UNDM) cars. Each train is made up of two 3-car units
London_Underground_1973_Stock
CSX rail yard in Selkirk, New York
freight train in the receiving yard is being pushed over the hump. Cars are separated (uncoupled) on the hump and sorted in the classification yard beyond.
Selkirk_Yard
Variation in the time intervals between heartbeats
well understood but there is experimental evidence to show that partial uncoupling of cardiac pacemaker cells from autonomic neural control may play a role
Heart_rate_variability
American psychological horror television series (2019–2023)
2021. Kroll, Justin (February 23, 2021). "Netflix Acquires Spec Script 'Uncoupled' From Escape Artists And 'Man From Toronto' Scribe". Deadline Hollywood
Servant_(TV_series)
Bridge in New York City
Myrtle Avenue Line trains), elevated trains bound for Manhattan were uncoupled from their steam locomotives. The elevated trains were then coupled to
Brooklyn_Bridge
generate ATP from the electrochemical gradient (in A.ferrooxidans); (6) Uncouplers (uncharged compounds), such as organic acids, permeate the membrane and
Acidophiles in acid mine drainage
Acidophiles_in_acid_mine_drainage
Topics referred to by the same term
The amelioration of coupling in computer programming Uncoupling of railway carriages Uncoupling (disambiguation) Coupling (disambiguation) This disambiguation
Decoupling
Cloud-based computer-aided engineering (CAE) and simulation platform"
had 600,000 registered users on its platform. The thermal module allows uncoupled thermo-mechanical, conjugate heat transfer and convective heat transfer
SimScale
Protein-coding gene in the species Homo sapiens
arsenic-containing substance negative regulation of oxidative phosphorylation uncoupler activity regulation of proton-transporting ATPase activity, rotational
PPIF
Type of rolling stock used on the London Underground
unit consisting of a Driving Motor car (DM), a Trailer car (T) and an Uncoupling Non-Driving Motor car (UNDM). The six-car trains are therefore formed
London_Underground_1995_Stock
Munich S-Bahn station
opened in 1998 as an alternative to S8. So line S1 services are coupled or uncoupled at Neufahrn station. Usually the rear section of the train goes to Munich
Neufahrn_bei_Freising_station
Regional airline in South Africa
www.engineeringnews.co.za. Retrieved 14 May 2021. "Airlink begins SAA uncoupling; Eswatini unit pursues own AOC". ch-aviation. Retrieved 14 May 2021. "Spreading
Airlink
Process of releasing energy from nutrients using inorganic electron acceptors
dissipate the proton gradient creating an apparently leaky mitochondria. An uncoupling protein known as thermogenin is expressed in some cell types and is a
Cellular_respiration
Quasiparticle form phonon and photon coupling
Dispersion relation of phonon polaritons in GaP. Red curves are the uncoupled phonon and photon dispersion relations, black curves are the result of coupling
Phonon_polariton
Heritage railroad at Disneyland Paris
approached the Frontierland station with its train, the front car was uncoupled from the other four cars. When the locomotive stopped at Frontierland
Disneyland_Railroad_(Paris)
American actor, writer and director (born 1967)
Role Notes 2024 American Horror Stories Aaron Episode: "Backrooms" 2022 Uncoupled Dennis 2 episodes 2021 Halston Joe Eula 5 episodes 2020 The Plot Against
David_Pittu
GABA receptor antagonist drug and benzodiazepine antidote
benzodiazepine binding site where such receptors have become more numerous and uncoupling/down-regulation of GABAA has been reversed. After long-term exposure to
Flumazenil
Medical condition
experiment, two narcotics, tricaine methanesulfonate and 1-octanol, and two uncouplers of oxidative phosphorylation, pentachlorophenol and 2,4-dinitrophenol
Fish_acute_toxicity_syndrome
Sexual orientation to men/masculinity or women/femininity
Surrogate phonology and transsexual faggotry: A linguistic analogy for uncoupling sexual orientation from gender identity. In Queerly Phrased: Language
Androphilia_and_gynephilia
Semi-automatic railroad coupler
particularly that of tank cars, emphasized the need to prevent cars uncoupling in the event of a derailment. Several variations of the standard knuckle
Janney_coupler
American actor and professional chef
Princess Bride Princess Buttercup Episode: "Chapter Five: Life Is Pain" 2022 Uncoupled Jerry Episode: "Chapter 6" 2023 Drag Me to Dinner Himself (judge) 10 episodes
David_Burtka
American stage actor
County Spelling Bee. He has also appeared on television in series such as Uncoupled, Evil, and Helpsters. Vora, Shivani. "New York Through The Eyes Of '&
Philippe_Arroyo
American stage actor
limited film and television work, appearing in the 2022 Netflix series Uncoupled. He received Tony Award and Drama Desk Award nominations for playing various
Brooks_Ashmanskas
Electric multiple unit that operates Eurostar's high-speed rail service
power cars can be uncoupled, specialised depot equipment is needed to split carriages by lifting the entire train at once. Once uncoupled, one of the carriage
British_Rail_Class_373
Chemical compound
Bromethalin works by being metabolised to n-desmethyl-bromethalin and uncoupling mitochondrial oxidative phosphorylation, which causes a decrease in adenosine
Bromethalin
UNCOUPLING
UNCOUPLING
UNCOUPLING
UNCOUPLING
Girl/Female
Hindu, Indian
Amazing; Loyal; Intelligent; Beautiful
Surname or Lastname
English
English : occupational name for someone who thatched cottages with reeds, from an agent derivative of Middle English rēd(en) ‘to cover with reeds’.Americanized spelling of German Rieder.
Surname or Lastname
English (Kent)
English (Kent) : variant spelling of Denn.
Girl/Female
Tamil
Ascending, Growing
Girl/Female
Indian
Goddess of Lakshmi
Boy/Male
Muslim
Forgiver
Boy/Male
Teutonic
Rules an estate.
Male
French
 Variant form of Norman French Asce, ACE means "noble at birth." Compare with another form of Ace.
Surname or Lastname
English
English : variant of Harold 1 and 2.
Boy/Male
Hindu
Noble, From a good family
UNCOUPLING
UNCOUPLING
UNCOUPLING
UNCOUPLING
UNCOUPLING