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Chemical compound
17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone
17α-Hydroxyprogesterone
Chemical compound
authorizations of medications containing 17-hydroxyprogesterone caproate in the European Union. Hydroxyprogesterone caproate is a progestin medication which
Hydroxyprogesterone_caproate
Chemical compound
Hydroxyprogesterone acetate (OHPA), sold under the brand name Prodox, is an orally active progestin related to hydroxyprogesterone caproate (OHPC) which
Hydroxyprogesterone_acetate
Drug class
include the 17α-hydroxyprogesterone derivatives medroxyprogesterone acetate, megestrol acetate, cyproterone acetate, and hydroxyprogesterone caproate, the
Progestogen_ester
Chemical compound
Hydroxyprogesterone heptanoate (OHPH), also known as hydroxyprogesterone enanthate (OHPE) and sold under the brand names H.O.P., Lutogil A.P., and Lutogyl
Hydroxyprogesterone heptanoate
Hydroxyprogesterone_heptanoate
Pharmaceutical combination
Estradiol valerate/hydroxyprogesterone caproate (EV/OHPC), sold under the brand names Gravibinon and Injectable No. 1 (or Chinese Injectable No. 1) among
Estradiol valerate/hydroxyprogesterone caproate
Estradiol_valerate/hydroxyprogesterone_caproate
Absence of a menstrual period in a woman of reproductive age
and 17-hydroxyprogesterone levels should be obtained if there is evidence of excess androgens, such as hirsutism or acne. 17-hydroxyprogesterone is elevated
Amenorrhea
Excess androgens in the body
medications. Diagnosis often involves blood tests for testosterone, 17-hydroxyprogesterone, and prolactin, as well as a pelvic ultrasound. Treatment depends
Hyperandrogenism
Genetic disorders of the adrenal gland
birth. This test detects elevated levels of 17α-hydroxyprogesterone (17-OHP). Detecting high levels of 17-OHP enables early detection of CAH. Newborns detected
Congenital adrenal hyperplasia
Congenital_adrenal_hyperplasia
Medical condition
PMC 10329939. PMID 37401054. Polat S, Arslan YK (March 2022). "17-Hydroxyprogesterone Response to Standard Dose Synacthen Stimulation Test in CYP21A2
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Congenital_adrenal_hyperplasia_due_to_21-hydroxylase_deficiency
Excessive hair growth on parts of the body where hair is usually minimal
polyendocrine metabolic ovarian syndrome (PMOS), as well as 17α-hydroxyprogesterone (because of the possibility of finding non-classic 21-hydroxylase
Hirsutism
Medical condition
21-hydroxylase deficiency is screened by measuring serum levels of 17α-hydroxyprogesterone (17-OHP) in the morning and between day 3 and 5 of the menstrual cycle
Late onset congenital adrenal hyperplasia
Late_onset_congenital_adrenal_hyperplasia
Psychological effect of drug intake
drugs that inhibit the actions of androgens. Cyproterone acetate, a 17-hydroxyprogesterone acetate derivative, is a very potent one and is widely used. Though
Drugs_and_sexual_desire
Medical conditions involving the development of the reproductive system
would occur if the patient has multiple malformation syndromes. 17-Hydroxyprogesterone can be used to screen for congenital adrenal hyperplasia (CAH).
Disorders_of_sex_development
aldosterone, corticosterone, 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, cortisol, and cortisone during infancy and childhood". Pediatr
List_of_steroid_abbreviations
Rare autosomal recessive disorder causing impaired masculinisation
Androstenedione is created from dehydroepiandrosterone (DHEA) or 17-hydroxyprogesterone. A deficiency in the HSD17B3 gene is characterized biochemically
17β-Hydroxysteroid dehydrogenase III deficiency
17β-Hydroxysteroid_dehydrogenase_III_deficiency
Human enzyme that hydroxylates steroids
and blood sugar control. The enzyme converts progesterone and 17α-hydroxyprogesterone into 11-deoxycorticosterone and 11-deoxycortisol, respectively, within
21-Hydroxylase
Series of interconnected biochemical reactions
age with increased levels of precursors like progesterone or 17α-hydroxyprogesterone. This activation can lead to symptoms of hyperandrogenism such as
Androgen_backdoor_pathway
Describes a new class of consumer health testing
always been expected for consumer-facing diagnostic tests. However, on April 17, 2025, a federal court blocked FDA's final rule on LDTs, creating uncertainty
Direct-to-consumer blood testing
Direct-to-consumer_blood_testing
Class of enzymes
enzymology, a 17α-hydroxyprogesterone aldolase (EC 4.1.2.30) is an enzyme that catalyzes the chemical reaction 17α-hydroxyprogesterone ⇌ {\displaystyle
17-alpha-hydroxyprogesterone aldolase
17-alpha-hydroxyprogesterone_aldolase
(hCG) levels throughout pregnancy. Estrogen, progesterone, and 17α-hydroxyprogesterone (17α-OHP) levels during pregnancy in women. The dashed vertical lines
Physiological changes in pregnancy
Physiological_changes_in_pregnancy
Steroidal progestin drug
contraction of 6α-methyl-17α-hydroxyprogesterone. It is closely related to medrogestone as well as other unesterified 17α-hydroxyprogesterone derivatives such as
Medroxyprogesterone
Chemical compound
pregnenolone to progesterone (92%) and 17- hydroxyprogesterone (59%); and 17-hydroxy- pregnenolone to 17- hydroxyprogesterone (83%). With a ... Influences of
Medrogestone
Primary male sex hormone
Testosteron (Androsten-3-ol-17-ol) [The crystalline production of the testicle hormone, testosterone (Androsten-3-ol-17-ol)]". Helvetica Chimica Acta
Testosterone
Topics referred to by the same term
17P or 17.P or 17-P may refer to: 17P/Holmes, a comet SpaceShipOne flight 17P, a commercial spaceflight 17α-Hydroxyprogesterone, a steroid hormone and
17P
Chemical compound
derivative of progesterone and 17α-hydroxyprogesterone. Closely related analogues of algestone include 16α-hydroxyprogesterone, algestone acetonide, and algestone
Algestone
Medical condition
have shown it, some authors have proposed that hydrocortisone or 17-α-hydroxyprogesterone may cause initial sensitization due to their cross-sensitivity
Autoimmune progesterone dermatitis
Autoimmune_progesterone_dermatitis
Chemical compound
intermediate product within the androgen backdoor pathway in which 17α-hydroxyprogesterone (17-OHP) is 5α-reduced and finally converted to 5α-dihydrotestosterone
5α-Pregnane-3α,17α-diol-20-one
5α-Pregnane-3α,17α-diol-20-one
Human hormone
testosterone. DHT may also be synthesized from progesterone and 17α-hydroxyprogesterone via the androgen backdoor pathway in the absence of testosterone
Dihydrotestosterone
Combination drug
Progesterone/hydroxyprogesterone heptanoate/α-tocopherol palmitate (P4/OHPH/VE), sold under the brand name Tocogestan, is a combination medication of
Progesterone/hydroxyprogesterone heptanoate/α-tocopherol palmitate
Progesterone/hydroxyprogesterone_heptanoate/α-tocopherol_palmitate
Chemical compound
ISSN 0028-1042. S2CID 46648877. Davis ME, Wied GL (October 1957). "17-alpha-HYDROXYPROGESTERONE acetate; an effective progestational substance on oral administration"
Ethisterone
Chemical compound
17α-hydroxy-dihydroprogesterone (17-OH-DHP) is an endogenous steroid, a metabolite of 17α-hydroxyprogesterone. 5α-Pregnan-17α-ol-3,20-dione (17-OH-DHP) is a progestogen
5α-Pregnan-17α-ol-3,20-dione
Chemical compound
16α-Hydroxyprogesterone (16α-OHP), also known as 16α-hydroxypregn-4-ene-3,20-dione, is a minor endogenous progestogen steroid hormone and a metabolite
16α-Hydroxyprogesterone
(11-oxocorticosterone, 17-deoxycortisone) = 21-hydroxypregn-4-ene-3,11,20-trione 11-Deoxycorticosterone (deoxycortone, desoxycortone; 21-hydroxyprogesterone) = 21-hydroxypregn-4-ene-3
List_of_corticosteroids
Chemical compound
1972). "Synthesis and biological activity of 17-esters of 6-dehydro-16-methylene-17 -hydroxyprogesterones". Journal of Medicinal Chemistry. 15 (7): 716–720
Methenmadinone_caproate
Combination drug
Estradiol hexahydrobenzoate/hydroxyprogesterone caproate/testosterone hexahydrobenzoate (EHHB/OHPC/THHB), sold under the brand name Trinestril AP, is
Estradiol hexahydrobenzoate/hydroxyprogesterone caproate/testosterone hexahydrobenzoate
Estradiol_hexahydrobenzoate/hydroxyprogesterone_caproate/testosterone_hexahydrobenzoate
Chemical compound
17α-Hydroxyprogesterone 17α-Methylprogesterone 19-Norprogesterone Engel CR, Jahnke H (November 1957). "Steroids and related products. X. 17 alpha-Bromoprogesterone
17α-Bromoprogesterone
Steroid hormone that activates the progesterone receptor
binding and stimulation of gene expression by progesterone, 17-alpha hydroxyprogesterone caproate, and related progestins". Am. J. Obstet. Gynecol. 197
Progestogen
Injectable form of birth control
Syntex SA US granted 3377364, Spero G, "6-methyl-17alpha-hydroxyprogesterone, the lower fatty acid 17-acylates and methods for producing the same", published
Medroxyprogesterone_acetate
Chemical compound
20α-Dihydroprogesterone (20α-DHP), also known as 20α-hydroxyprogesterone (20α-OHP), is a naturally occurring, endogenous progestogen. It is a metabolite
20α-Dihydroprogesterone
Chemical compound
List of progestogen esters § Esters of 17α-hydroxyprogesterone derivatives 16-Methylene-17α-hydroxyprogesterone acetate Stĕrba R (March 1970). "[Towards
Bromethenmadinone_acetate
Protein-coding gene in humans
group at carbon 17 position (C17) of the steroid D ring (the 17α-hydroxylase activity, EC 1.14.14.19), or acts upon 17α-hydroxyprogesterone and 17α-hydroxypregnenolone
CYP17A1
Chemical compound
Name, BANTooltip British Approved Name) is a progestin of the 17α-hydroxyprogesterone group which was, until recently, never marketed or used clinically
Megestrol
Chemical compound
also known as deacetylsuperlutin or as 16-methylene-6-dehydro-17α-hydroxyprogesterone, is a pregnane steroid which was never marketed. It is a parent compound
Methenmadinone
Medical condition
17α-hydroxyprogesterone. As 17,20-lyase it mediates 17α-hydroxypregnenolone → DHEA. An expected second 17,20-lyase reaction (17α-hydroxyprogesterone → androstenedione)
Congenital adrenal hyperplasia due to 17α-hydroxylase deficiency
Congenital_adrenal_hyperplasia_due_to_17α-hydroxylase_deficiency
Chemical compound
Savchenko ON, Stepanov MG (1987). "[Hormonal properties of new 17 alpha-hydroxyprogesterone derivatives]". Problemy Endokrinologii (in Russian). 33 (3):
Acetomepregenol
Chemical compound
Vister in Italy in 1961. It is the 3-cyclopentyl enol ether of 17α-hydroxyprogesterone acetate. PGA, along with quingestrone (the 3-cyclopentyl enol ether
Pentagestrone_acetate
Progestin medication
in ewes and goats. FGA, also known as 17α-acetoxy-9α-fluoro-11β-hydroxyprogesterone or as 17α-acetoxy-9α-fluoro-11β-hydroxypregn-4-ene-3,20-dione, is
Flugestone_acetate
Class of enzymes
17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving), androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating
Ketosteroid_monooxygenase
Combination drug
Estradiol dibutyrate/hydroxyprogesterone heptanoate/testosterone caproate (EDBu/OHPH/TCa), sold under the brand name Triormon Depositum, is an injectable
Estradiol dibutyrate/hydroxyprogesterone heptanoate/testosterone caproate
Estradiol_dibutyrate/hydroxyprogesterone_heptanoate/testosterone_caproate
Veterinary progestin and antiandrogen
DMA include other 17α-hydroxyprogesterone derivatives such as chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, medroxyprogesterone
Delmadinone_acetate
Chemical compound
acetate Hydroxyprogesterone acetate Hydroxyprogesterone caproate (hydroxyprogesterone hexanoate) Hydroxyprogesterone heptanoate (hydroxyprogesterone enanthate)
6α-Methyl-17α-bromoprogesterone
6α-Methyl-17α-bromoprogesterone
Main sweet-tasting constituent of liquorice
extreme cases, death can occur as a result of excess consumption. 11α-Hydroxyprogesterone Glycyrrhetinic acid List of unusual deaths in the 21st century van
Glycyrrhizin
Chemical compound
Sakuragi N, Fujimoto S (March 1992). "The physiological role of estradiol 17-sulfate during pregnancy". J. Steroid Biochem. Mol. Biol. 41 (3–8): 567–70
Estradiol_17β-sulfate
Chemical compound
derivative of progesterone. It is specifically a derivative of 17α-hydroxyprogesterone with a methyl group at the C6 position, a methylene group at the
Melengestrol_acetate
Chemical compound
List of progestogen esters § Esters of 17α-hydroxyprogesterone derivatives 16-Methylene-17α-hydroxyprogesterone acetate Sterba R (1968). "New biological
Chlormethenmadinone_acetate
Chemical compound
derivative of progesterone and 17α-hydroxyprogesterone. It is specifically a derivative of 17α-hydroxyprogesterone with a trifluoromethyl group at the
Flumedroxone_acetate
Chemical compound
11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is
11-Deoxycorticosterone
Chemical compound
Hydroxyprogesterone heptanoate benzilic acid hydrazone (OHPHBH), also known as 17α-hydroxyprogesterone 17α-heptanoate 3-benzilic acid hydrazone, is a progestin
Hydroxyprogesterone heptanoate benzilic acid hydrazone
Hydroxyprogesterone_heptanoate_benzilic_acid_hydrazone
Chemical compound
20β-Dihydroprogesterone (20β-DHP), also known as 20β-hydroxyprogesterone (20β-OHP), is an endogenous metabolite of progesterone which is formed by 20β-hydroxysteroid
20β-Dihydroprogesterone
Chemical compound
intramuscular hydroxyprogesterone caproate. Hence, gestonorone caproate is approximately 5- to 10-fold more potent than hydroxyprogesterone caproate in
Gestonorone_caproate
Combination drug
Estradiol diundecylate/hydroxyprogesterone heptanoate/testosterone cyclohexylpropionate (EDU/OHPH/TCHP), sold under the brand name Trioestrine Retard
Estradiol diundecylate/hydroxyprogesterone heptanoate/testosterone cyclohexylpropionate
Estradiol_diundecylate/hydroxyprogesterone_heptanoate/testosterone_cyclohexylpropionate
Chemical compound
11-Dehydrocorticosterone (11-DHC), also known as 11-oxocorticosterone or 17-deoxycortisone, as well as 21-hydroxypregn-4-ene-3,11,20-trione, is a naturally
11-Dehydrocorticosterone
Chemical compound
both more potent and longer-acting than the related progestogen hydroxyprogesterone caproate. The progestogenic potency of DHPA is about 2 to 5 times
Algestone_acetophenide
Substance that quells or blunts the libido
dehydrogenase and 17,20-lyase, which catalyzes the conversion of 17α-hydroxyprogesterone to androstenedione to testosterone. In one study a group of men were
Anaphrodisiac
Chemical compound
Betamethasone valerate is a synthetic glucocorticoid ester. It is the 17-valerate ester of betamethasone. Betamethasone valerate is often used to treat
Betamethasone_valerate
Chemical compound
7α-Acetylthio-17α-hydroxyprogesterone 7α-Thiomethylspironolactone (SC-26519) 7α-Thioprogesterone (SC-8365) 7α-Thiospironolactone (SC-24813) 16α-Hydroxyprogesterone
Esaxerenone
Chemical compound
3α-Dihydroprogesterone (3α-DHP), also known as 3α-hydroxyprogesterone, as well as pregn-4-en-3α-ol-20-one, is an endogenous neurosteroid. It is biosynthesized
3α-Dihydroprogesterone
Chemical compound
3β-Dihydroprogesterone (3β-DHP), also known as 3β-hydroxyprogesterone, or pregn-4-en-3β-ol-20-one (4-pregnenolone, δ4-pregnenolone), is an endogenous
3β-Dihydroprogesterone
Chemical compound
11α-Hydroxyprogesterone (11α-OHP), or 11α-hydroxypregn-4-ene-3,20-dione is an endogenous steroid and metabolite of progesterone. It is a weak antiandrogen
11α-Hydroxyprogesterone
Chemical compound
pregnenolone to DHEA. 17α-Hydroxypregnenolone is also converted to 17α-hydroxyprogesterone, a prohormone for glucocorticosteroids and androstenedione through
17α-Hydroxypregnenolone
Chemical compound
Hydromadinone (INN), also known as 6α-chloro-17α-hydroxyprogesterone, is a steroidal progestin of the 17α-hydroxyprogesterone group which was patented in 1967 but
Hydromadinone
Chemical compound
Gent R, Barnard L, Swart AC (2018). "The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor
11β-Hydroxytestosterone
Chemical compound
20,21-anhydro-17-/3-hydroxyprogesterone. * Prodox, Upjohn Co., Kalamazoo, Michigan [...] It was found that 17-a-hydroxyprogesterone acetate has a progestational
Dimethisterone
Medication producing effects similar to progesterone
University Press. pp. 126–. ISBN 978-1-107-45182-7. Meis PJ (May 2005). "17 hydroxyprogesterone for the prevention of preterm delivery". Obstetrics and Gynecology
Progestogen_(medication)
Chemical compound
progestogenic activity. Subsequent investigations revealed that 17-isoprogesterone and 14-iso-17-isoprogesterone are devoid of progestogenic activity. 19-Norprogesterone
19-Norprogesterone
Chemical compound
synthetic pregnane steroid and a derivative of progesterone and 17α-hydroxyprogesterone. It is a C14α,17α cyclic ketal of 14α,17α-dihydroxyprogesterone.
Proligestone
Chemical compound
11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone) 11-Deoxycortisol 11-Deoxycorticosterone 11β-Hydroxyprogesterone (21-deoxycorticosterone)
7α-Hydroxycholesterol
Chemical compound
11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone) 11-Deoxycortisol 11-Deoxycorticosterone 11β-Hydroxyprogesterone (21-deoxycorticosterone)
Androstenone
Class of enzymes
following redox reactions of sex steroids:[citation needed] 20α-Hydroxyprogesterone ↔ Progesterone DHEATooltip Dehydroepiandrosterone ↔ Androstenediol
17β-Hydroxysteroid dehydrogenase
17β-Hydroxysteroid_dehydrogenase
Chemical compound
Epietiocholanolone, also known as 3β-hydroxy-5β-androstan-17-one or as etiocholan-3β-ol-17-one, is an etiocholane (5β-androstane) steroid as well as an
Epietiocholanolone
Chemical compound
synthetic pregnane steroid and a derivative of progesterone and 17α-hydroxyprogesterone. It is the C3β cypionate (cyclopentylpropionate) ester of megestrol
Cymegesolate
Chemical compound
Improvement in arterial blood flow has been demonstrated in coronary arteries. 17-beta-estradiol (E2) is considered the most potent estrogen found in humans
Estradiol
Steroid medication
7α-Acetylthio-17α-hydroxyprogesterone 7α-Thiomethylspironolactone (SC-26519) 7α-Thioprogesterone (SC-8365) 7α-Thiospironolactone (SC-24813) 16α-Hydroxyprogesterone
Prednisone
Chemical compound
17α-hydroxyprogesterone. It is structurally related to other 17α-hydroxyprogesterone derivatives such as chlormadinone acetate, hydroxyprogesterone caproate
Cyproterone_acetate
Chemical compound
Hydrocortisone 17-butyrate is a form of hydrocortisone butyrate. Glucocorticoid Corticosteroid Brogden, R.N.; Pinder, R.M.; Sawyer, Phyllis R.; Speight
Hydrocortisone_17-butyrate
Chemical compound
synthetic pregnane steroid and a derivative of progesterone and 17α-hydroxyprogesterone. It is the C17α acetate ester of anagestone, which, in contrast to
Anagestone_acetate
Chemical compound
Barnard L, Swart AC (April 2018). "The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor
11-Ketoandrosterone
Antifungal chemical compound
significantly increase luteinizing hormone, progesterone, and 17α-hydroxyprogesterone levels, whereas levels of androstenedione, follicle-stimulating hormone
Ketoconazole
Chemical compound
6-diene-3,20-dione) is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed. An acetate ester, clomegestone acetate
Clomegestone
Chemical compound
synthetic pregnane steroid and a derivative of progesterone and 17α-hydroxyprogesterone. It is the C17α caproate (hexanoate) ester of megestrol. Closely
Megestrol_caproate
Chemical compound
21-Deoxycortisone, also known as 21-desoxycortisone, 11-keto-17α-hydroxyprogesterone, or 17α-hydroxypregn-4-ene-3,11,20-trione, is a naturally occurring
21-Deoxycortisone
Chemical compound
Gynaecology and Obstetrics. de Gruyter. p. 49. ISBN 9783110006148. 17α-Hydroxyprogesterone caproate is a depot progestogen which is entirely free of side actions
Dydrogesterone
Chemical compound
prolonged periods of time. Subsequent investigation found that 17α-hydroxyprogesterone derivatives included anagestone acetate, chlormadinone acetate, medroxyprogesterone
Ethynerone
Chemical compound
Gynaecology and Obstetrics. de Gruyter. p. 49. ISBN 9783110006148. 17α-Hydroxyprogesterone caproate is a depot progestogen which is entirely free of side actions
Levonorgestrel_butanoate
Drug class
mineralocorticoid antagonists is dependent on the presence of a y-lactone ring on the C-17 position. The C-7 position is also important for activity as substituents
Mineralocorticoid receptor antagonist
Mineralocorticoid_receptor_antagonist
Sex hormone
binding and stimulation of gene expression by progesterone, 17-alpha hydroxyprogesterone caproate, and related progestins". American Journal of Obstetrics
Progesterone
Concept in organic chemistry
17th–20th, 1959 Sponsored by CIBA / Ein Internationales Symposium Herrenchiemsee, 17.–20. Juni 1959 Veranstaltet mit Unterstützung der CIBA. Springer-Verlag. pp
Spirolactone
Class of steroid hormones
Corporation Marblehead, Massachusetts. Archived from the original on 2013-07-17. Retrieved 2013-06-23. Korte SM (March 2001). "Corticosteroids in relation
Corticosteroid
Chemical compound
11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone) 11-Deoxycortisol 11-Deoxycorticosterone 11β-Hydroxyprogesterone (21-deoxycorticosterone)
6β-Hydroxycortisol
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