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ADAM12

  • ADAM12
  • Human protein-coding gene

    humans is encoded by the ADAM12 gene. ADAM12 has two splice variants: ADAM12-L, the long form, has a transmembrane region and ADAM12-S, a shorter variant

    ADAM12

    ADAM12

    ADAM12

  • Metalloproteinase
  • Type of enzyme

    protease enzyme whose catalytic mechanism involves a metal. An example is ADAM12 which plays a significant role in the fusion of muscle cells during embryo

    Metalloproteinase

    Metalloproteinase

    Metalloproteinase

  • Myogenesis
  • Formation of muscular tissue, particularly during embryonic development

    Fusion in humans is aided by a set of metalloproteinases coded for by the ADAM12 gene, and a variety of other proteins. Fusion involves recruitment of actin

    Myogenesis

    Myogenesis

    Myogenesis

  • 1980s professional wrestling boom
  • Era of professional wrestling

    and The New Age Outlaws. 1980s portal History of professional wrestling Adam12 (May 8, 2023). "Throwback to Some Great WWE Golden Era Wrestlers & Gimmicks"

    1980s professional wrestling boom

    1980s professional wrestling boom

    1980s_professional_wrestling_boom

  • ADAM (protein)
  • Protein domain

    region of chromosome 17q21 previously defined by tumor deletion mapping. ADAM12 ADAM12, a metalloprotease that binds insulin growth factor binding protein-3

    ADAM (protein)

    ADAM (protein)

    ADAM_(protein)

  • WROR-FM
  • Classic hits radio station in Framingham–Boston, Massachusetts

    West. In May 2026, morning host Bob Bronson retired. He was replaced by Adam12, who joined Falcone on the morning show. From 2007 through 2011, WROR would

    WROR-FM

    WROR-FM

  • Development, Growth & Differentiation
  • Academic journal

    Satoshi Ansai, Masato Kinoshita and Atsuko Sehara-Fujisawa. 58 409-421 2016 ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage

    Development, Growth & Differentiation

    Development,_Growth_&_Differentiation

  • List of human protein-coding genes 1
  • HGNC:216; Q13443 254 ADAM10 HGNC:188; O14672 255 ADAM11 HGNC:189; O75078 256 ADAM12 HGNC:190; O43184 257 ADAM15 HGNC:193; Q13444 258 ADAM17 HGNC:195; P78536

    List of human protein-coding genes 1

    List_of_human_protein-coding_genes_1

  • Alpha-actinin-2
  • Protein found in humans

    Alpha-actinin 2 has been shown to interact with KCNA5, DLG1, DISC1, MYOZ1, GRIN2B, ADAM12, ACTN3, MYPN, PDLIM3, PKN, MYOT, TTN, NMDAR, SYNPO2, LDB3, and FATZ. The

    Alpha-actinin-2

    Alpha-actinin-2

    Alpha-actinin-2

  • LRP1
  • Mammalian protein found in Homo sapiens

    have been implicated in the proteolytic cleavage of LRP1 such as ADAM10, ADAM12, ADAM17 and MT1-MMP. LRP1 is also continuously endocytosed from the membrane

    LRP1

    LRP1

    LRP1

  • IGFBP3
  • Protein-coding gene in the species Homo sapiens

    promote the repair of DNA damage. IGFBP3 has been shown to interact with: ADAM12 ADAM28 COL1A1 FN1 IGFALS IGF1, IGF2 HSPA5 Humanin PLG RXRA TF KPNB1 PRKDC

    IGFBP3

    IGFBP3

    IGFBP3

  • PACSIN3
  • Protein-coding gene in the species Homo sapiens

    PMID 12477932. Mori S, Tanaka M, Nanba D, et al. (2003). "PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal

    PACSIN3

    PACSIN3

    PACSIN3

  • PIK3R1
  • Protein-coding gene in the species Homo sapiens

    are associated to SHORT syndrome. PIK3R1 has been shown to interact with: ADAM12, BCAR1, CBLB, CD117, CD28, CD7, CENTG1, CBL, EPHA2, EPOR, ERBB3, EZR, FCGR2A

    PIK3R1

    PIK3R1

    PIK3R1

  • SH3PXD2A
  • Protein-coding gene in the species Homo sapiens

    (2005). "Amyloid-beta neurotoxicity is mediated by FISH adapter protein and ADAM12 metalloprotease activity". Proc. Natl. Acad. Sci. U.S.A. 102 (8): 3058–63

    SH3PXD2A

    SH3PXD2A

    SH3PXD2A

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