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AXIN 2

  • Axin-2
  • Protein found in humans

    Axin-2, also known as axin-like protein (Axil), axis inhibition protein 2 (AXIN2), or conductin, is a protein that in humans is encoded by the AXIN2 gene

    Axin-2

    Axin-2

    Axin-2

  • Axin-1
  • Protein found in humans

    Axin-1 is a protein that in humans is encoded by the AXIN1 gene. This gene encodes a cytoplasmic protein which contains a regulator of G-protein signaling

    Axin-1

    Axin-1

    Axin-1

  • Cherry Grove Township, Michigan
  • Civil township in Michigan, United States

    census. Axin is an unincorporated community within the township at 44°12′36″N 85°32′51″W / 44.21000°N 85.54750°W / 44.21000; -85.54750. Axin was settled

    Cherry Grove Township, Michigan

    Cherry Grove Township, Michigan

    Cherry_Grove_Township,_Michigan

  • Catenin beta-1
  • Mammalian protein found in humans

    the same canonical fashion. The scaffold protein axin (two closely related paralogs, axin 1 and axin 2) contains a similar interaction motif on its long

    Catenin beta-1

    Catenin beta-1

    Catenin_beta-1

  • Dishevelled
  • Family of proteins

    protein as well as novel suppressing alleles of axin". Genetics. 161 (2): 747–62. doi:10.1093/genetics/161.2.747. PMC 1462152. PMID 12072470. Wallingford

    Dishevelled

    Dishevelled

    Dishevelled

  • Ashin
  • Taiwanese singer and songwriter

    Pe̍h-ōe-jī: Tân Sìn-hông), known professionally as Ashin (Chinese: 阿信; pinyin: Āxìn) (born 6 December 1975), is a Taiwan singer and songwriter. He is best known

    Ashin

    Ashin

    Ashin

  • AMP-activated protein kinase
  • Class of enzymes

    lysosomes via several systems of clinical significance. This includes the AXIN - LKB1 complex, acting in response to glucose limitations functioning independently

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • Frzb
  • inhibition complex. The combination of LRP-axin induces Dvl phosphorylation (P) which blocks the APC-axin-GSK3 complex from phosphorylating β-Cat. The

    Frzb

    Frzb

    Frzb

  • ZBED3
  • Protein-coding gene in the species Homo sapiens

    Zinc finger BED domain-containing protein 3 also known as axin-interacting protein is a protein in humans that is encoded by the ZBED3 gene. ZBED3 (Zinc

    ZBED3

    ZBED3

    ZBED3

  • Allele
  • Variant of DNA sequence at a locus

    2006). "Maternal methyl supplements increase offspring DNA methylation at Axin Fused". Genesis. 44 (9): 401–6. doi:10.1002/dvg.20230. PMID 16868943. S2CID 36938621

    Allele

    Allele

  • Big City Greens season 1
  • Season of television series

    2018). "'Big City Greens' Renewed For Season 2 Ahead Of Disney Channel Premiere". Deadline. Retrieved May 2, 2025. Sandberg, Bryn (March 4, 2016). "Disney

    Big City Greens season 1

    Big_City_Greens_season_1

  • Adenomatous polyposis coli
  • Protein found in humans

    complex" with glycogen synthase kinase 3-alpha and/or beta (GSK-3α/β) and Axin via interactions with the 20 AA and SAMP repeats. This complex is then able

    Adenomatous polyposis coli

    Adenomatous polyposis coli

    Adenomatous_polyposis_coli

  • Autocrine signaling
  • Signaling within the same cell

    inactivation of a protein complex containing the tumor suppressors APC and Axin. This destruction complex normally triggers β-catenin phosphorylation, inducing

    Autocrine signaling

    Autocrine signaling

    Autocrine_signaling

  • Glycogen synthase kinase-3 beta
  • Protein-coding gene in Homo sapiens

    Hamada F, Ishidate T, Anai K, Kawahara K, Toyoshima K, et al. (June 1998). "Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin

    Glycogen synthase kinase-3 beta

    Glycogen synthase kinase-3 beta

    Glycogen_synthase_kinase-3_beta

  • Bistra (Timiș)
  • River in Romania

    the river Bistra: Left: Pârâul Lupului, Bucovița, Marga, Bistra Mărului, Axin Right: Corni, Rusca, Valea Jghiabului, Valea Rugului, Ohaba, Glâmboca, Radina

    Bistra (Timiș)

    Bistra_(Timiș)

  • Wnt signaling pathway
  • Group of signal transduction pathways involved in embryonic development

    normally degrade it. This destruction complex includes the following proteins: Axin, adenomatosis polyposis coli (APC), protein phosphatase 2A (PP2A), glycogen

    Wnt signaling pathway

    Wnt_signaling_pathway

  • SDF–Syrian transitional government clashes (2025–2026)
  • Clashes in Syria (2025–2026)

    9 injured 2 injured, 4 injured, 2 injured 1 killed, unspecified number killed 9 injured, unspecified number injured, 59 injured 1 killed, 2 killed, During

    SDF–Syrian transitional government clashes (2025–2026)

    SDF–Syrian transitional government clashes (2025–2026)

    SDF–Syrian_transitional_government_clashes_(2025–2026)

  • GSK3B interacting protein
  • Protein-coding gene in the species Homo sapiens

    interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain

    GSK3B interacting protein

    GSK3B interacting protein

    GSK3B_interacting_protein

  • LRP5
  • Protein-coding gene in the species Homo sapiens

    (Apr 2001). "Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway". Molecular Cell. 7 (4):

    LRP5

    LRP5

    LRP5

  • DVL1
  • Human protein and coding gene

    Commun. 239 (2): 510–6. doi:10.1006/bbrc.1997.7500. PMID 9344861. Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A (1998). "Axin, a negative

    DVL1

    DVL1

    DVL1

  • Aleppo clashes (2025–2026)
  • Clashes between the SDF and the Syrian government

    December 2025.{{cite news}}: CS1 maint: deprecated archival service (link) "2 civilians injured in suicide drone attack on al-Shaqif area, Sheikh Maqsoud"

    Aleppo clashes (2025–2026)

    Aleppo clashes (2025–2026)

    Aleppo_clashes_(2025–2026)

  • SUMO2
  • Protein-coding gene in the species Homo sapiens

    SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation". The Journal of Biological

    SUMO2

    SUMO2

    SUMO2

  • Wexford County, Michigan
  • County in Michigan, United States

    Township Springville Township Wexford Township Boon Caberfae Haring Wedgewood Axin Bagnall Baxter Benson Garletts Corner Gilbert Glengary Harlan Hobart Hoxeyville

    Wexford County, Michigan

    Wexford County, Michigan

    Wexford_County,_Michigan

  • The Neverending Story (TV series)
  • 1995 Canadian TV series or program

    of Bastian's newly formed friendship with an interesting character named Axin, he goes to all limits to prove he is the better friend. 13 "The Three Feeling

    The Neverending Story (TV series)

    The_Neverending_Story_(TV_series)

  • Signalosome
  • clustering of LRP6 receptors with Dishevelled (Dvl) proteins to recruit the Axin complex for inactivation. B-cell receptor (BCR) signalosome: The B-cell receptor

    Signalosome

    Signalosome

  • DVL2
  • Human protein and coding gene

    42 (2): 302–10. doi:10.1006/geno.1997.4713. PMID 9192851. Strovel ET, Wu D, Sussman DJ (2000). "Protein phosphatase 2Calpha dephosphorylates axin and

    DVL2

    DVL2

    DVL2

  • Judika
  • Indonesian singer, actor and record producer (born 1978)

    music videos. Newcomers who signed are Dnanda, Daniel Pattinama, Yan Josua, Axin and Nurlela. Judika was one of the singers who received the title KRH (Kanjeng

    Judika

    Judika

    Judika

  • Naked cuticle
  • Protein family

    sequence that mediates homo-oligomerization and hetero-oligomerization with Axin. Vertebrate and invertebrate Nkd proteins have additional unique regions

    Naked cuticle

    Naked_cuticle

  • January 16
  • Day of the year

    Feminist Society Emerges". Haaretz. Retrieved 16 October 2019. TOLHILDAN, AXİN (27 August 2018). "Muslim: Our goal is for TEV-DEM to organize the 3rd territory"

    January 16

    January_16

  • Biomolecular condensate
  • Class of membrane-less organelles within biological cells

    supramolecular complex (the Axin complex) to Wnt receptors at the plasma membrane. The formation of these Dishevelled and Axin containing droplets is conserved

    Biomolecular condensate

    Biomolecular condensate

    Biomolecular_condensate

  • List of Big City Greens episodes
  • Metcalf (July 3, 2018). "Top 150 Monday Cable Originals & Network Finals: 7.2.2018". Showbuzz Daily. Archived from the original on July 4, 2018. Retrieved

    List of Big City Greens episodes

    List_of_Big_City_Greens_episodes

  • Cell signaling
  • System of communication

    Heidelberg: Springer, pp. 1–21, doi:10.1007/978-3-540-74805-2_1, ISBN 978-3-540-74805-2, PMID 18064409 Pandit, Nikita K. (2007). Introduction To The

    Cell signaling

    Cell signaling

    Cell_signaling

  • DVL3
  • Protein-coding gene in humans

    Commun. 239 (2): 510–516. doi:10.1006/bbrc.1997.7500. PMID 9344861. Kishida S, Yamamoto H, Hino S, et al. (1999). "DIX domains of Dvl and axin are necessary

    DVL3

    DVL3

    DVL3

  • 2022 PCS season
  • Sports season

    tiebreaker match. SEM9 had the better head-to-head record against Dewish Team (2–0). Format: Double elimination Winner and runner-up qualify for the 2022 World

    2022 PCS season

    2022_PCS_season

  • GSK-3
  • Class of enzymes

    of Beta-catenin by GSK-3 is mediated by the binding of both proteins to Axin, a scaffold protein, allowing Beta-catenin to access the active site of GSK-3

    GSK-3

    GSK-3

    GSK-3

  • Catenin
  • Type of protein

    in disorders like cancer by responding to mutations in β-catenin, APC or Axin, each of which can lead to this de-regulated β-catenin level stabilization

    Catenin

    Catenin

    Catenin

  • Casein kinase 1, alpha 1
  • Enzyme found in humans

    (May 2002). "Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways". The Journal of Biological Chemistry. 277

    Casein kinase 1, alpha 1

    Casein kinase 1, alpha 1

    Casein_kinase_1,_alpha_1

  • Primitive streak
  • Structure in early amniote embryogenesis

    addition, mutating the intracellular negative regulator of Wnt signaling, Axin, and misexpression of the chick cWnt8C produces multiple streaks in mouse

    Primitive streak

    Primitive streak

    Primitive_streak

  • Kang-Yell Choi
  • South Korean biotechnologist

    Journal of Investigative Dermatology. (2017) Small molecule binding of the Axin-RGS domain promotes β-catenin and Ras degradation. Nature Chemical Biology

    Kang-Yell Choi

    Kang-Yell_Choi

  • Mexican lacquerware
  • the extraction of a greasy substance from the larvae of the coccus axin or llaveia axin insect. To extract this substance for lacquering, the larvae are

    Mexican lacquerware

    Mexican lacquerware

    Mexican_lacquerware

  • SENP2
  • Protein-coding gene in the species Homo sapiens

    SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation". J. Biol. Chem. 276 (42):

    SENP2

    SENP2

    SENP2

  • DYNLT1
  • Protein-coding gene in the species Homo sapiens

    Wu D, Sussman DJ (2000). "Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription". J. Biol. Chem. 275 (4): 2399–403

    DYNLT1

    DYNLT1

    DYNLT1

  • Presenilin-1
  • Protein-coding gene in the species Homo sapiens

    "Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis". Cell. 110 (6):

    Presenilin-1

    Presenilin-1

    Presenilin-1

  • Ahmet Ağaoğlu
  • Turkish politician (1869–1939)

    driven a sword into the hearts of 60 million Turks. After this incident, the Axın newspaper was shut down by the government in September 1933. In its final

    Ahmet Ağaoğlu

    Ahmet Ağaoğlu

    Ahmet_Ağaoğlu

  • Hasakah Governorate campaign (2012–2014)
  • Syrian military campaign

    forces afterwards took control of all government institutions in the town. On 2 August 2012, the National Coordination Committee for Democratic Change announced

    Hasakah Governorate campaign (2012–2014)

    Hasakah Governorate campaign (2012–2014)

    Hasakah_Governorate_campaign_(2012–2014)

  • Marc Kirschner
  • American biologist (born 1945)

    Kirschner, Marc W (2003-10-13). Roel Nusse (ed.). "The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway". PLOS

    Marc Kirschner

    Marc Kirschner

    Marc_Kirschner

  • Casein kinase 1
  • Family of protein kinases

    LRP by CK1gamma. Phosphorylation of LRP6 by CK1gamma promotes binding of axin to LRP and activation of the Wnt signaling pathway. CK1ε and CK1δ are essential

    Casein kinase 1

    Casein_kinase_1

  • PPM1A
  • Protein-coding gene in the species Homo sapiens

    Sussman DJ (January 2000). "Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription". The Journal of Biological Chemistry

    PPM1A

    PPM1A

    PPM1A

  • MAP3K4
  • Protein-coding gene in the species Homo sapiens

    242603899. PMC 139241. PMID 12477932. Luo W, Ng WW, Jin LH, et al. (2003). "Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK

    MAP3K4

    MAP3K4

    MAP3K4

  • Hopsan
  • Ssimulation environment for fluid and mechatronic systems

    Cores". The Twelfth Scandinavian International Conference on Fluid Power. Axin, M.; Braun, R.; Dell'Amico, A.; Eriksson, B.; Nordin, P.; Pettersson, K.;

    Hopsan

    Hopsan

    Hopsan

  • Solon language
  • Dialect of the Evenki language

    Hailar/Bouthka, Orončo, Manegir, Onkor/Xinjian and Turkestan Solon, with the latter 2 most likely being an identical dialect. There is also a different grouping

    Solon language

    Solon language

    Solon_language

  • Ubiquitin C
  • Mammalian protein found in humans

    PMID 18495657. Guo X, Ramirez A, Waddell DS, Li Z, Liu X, Wang XF (January 2008). "Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling". Genes

    Ubiquitin C

    Ubiquitin C

    Ubiquitin_C

  • Anarchism in Syria
  • Feminist Society Emerges". Haaretz. Retrieved 16 October 2019. TOLHILDAN, AXİN (27 August 2018). "Muslim: Our goal is for TEV-DEM to organize the 3rd territory"

    Anarchism in Syria

    Anarchism_in_Syria

  • Assaf Friedler
  • Israeli organic chemist and biochemist

    tryptophan and lysine suppress the aggregation of a cancer-related mutant of the Axin protein". RSC Chemical Biology. 6 (8): 1270–1277. doi:10.1039/D5CB00141B

    Assaf Friedler

    Assaf Friedler

    Assaf_Friedler

  • Handcrafts and folk art in Michoacán
  • Folk art

    a pre Hispanic method using a wax derived from the female insect coccus axin found in the Tierra Caliente, as well as chia, chicalote or more recently

    Handcrafts and folk art in Michoacán

    Handcrafts and folk art in Michoacán

    Handcrafts_and_folk_art_in_Michoacán

  • FRAT1
  • Protein-coding gene in the species Homo sapiens

    in advanced T-cell lymphomas". Li L, Yuan H, Weaver CD, et al. (1999). "Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated

    FRAT1

    FRAT1

    FRAT1

  • Clancy's Tavern
  • 2011 studio album by Toby Keith

    electric guitar (tracks 2, 7) Steve Nathan - B-3 organ (tracks 1, 2, 4, 5, 7, 11), piano (tracks 1, 2, 4, 5, 7, 11), Wurlitzer (tracks 1, 2, 4, 5, 7, 11) Russ

    Clancy's Tavern

    Clancy's_Tavern

  • Plakoglobin
  • Mammalian protein found in Homo sapiens

    kinase 3β (GSK3β) and scaffold proteins adenomatous polyposis coli (APC) and axin targets plakoglobin for degradation.[31–33]. The phosphorylated motif is

    Plakoglobin

    Plakoglobin

    Plakoglobin

  • Meng Anming
  • Chinese biologist

    organizer and body axis formation in the zebrafish and frog by promoting Axin degradation. Their discovery solves a long-standing question in the field

    Meng Anming

    Meng Anming

    Meng_Anming

  • 2021 PCS season
  • Sports season

    Maple Unified Kaiwing Helper Winged Berjaya Dragons Azhi Enso Minji Eren K2 Axin BOOM Esports Rockky Epic Ruby Wako PoP Warlock Hammock Impunity Esports TOPKING

    2021 PCS season

    2021_PCS_season

  • Casein kinase 1 isoform epsilon
  • Protein and coding gene in humans

    (May 2002). "Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways". The Journal of Biological Chemistry. 277

    Casein kinase 1 isoform epsilon

    Casein kinase 1 isoform epsilon

    Casein_kinase_1_isoform_epsilon

  • PIAS1
  • Protein-coding gene in the species Homo sapiens

    Zhang Y, Lin SC (2003). "SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling". J. Biol

    PIAS1

    PIAS1

    PIAS1

  • I Can See Your Voice Indonesia season 5
  • Television game show season

    #dennycaknan jago tebak penyanyi misterius!" (Tweet) (in Indonesian). Retrieved 2 February 2021 – via Twitter. @ICanSeeINA (8 February 2021). "Dari Laksamana

    I Can See Your Voice Indonesia season 5

    I_Can_See_Your_Voice_Indonesia_season_5

  • MACF1
  • Protein-coding gene in humans

    complex containing axin, β-catenin, GSK3β, and APC. However, upon Wnt signaling, MACF1 is involved in a translation and binding of the axin complex to LTP6

    MACF1

    MACF1

    MACF1

  • 2020 PCS season
  • Sports season

    Unified Kaiwing Bigfafa Saroo Berjaya Dragons Azhi Enso Maoan K2 Chilly Do1u1u Axin Paul Liyab Esports Kanji Doedoii Rex Dawn Mocha Cabbage Tgee Nova Esports

    2020 PCS season

    2020_PCS_season

  • PPP2R5C
  • Protein-coding gene in the species Homo sapiens

    can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin". Oncogene. 19 (4): 537–45. doi:10.1038/sj.onc.1203359. PMID 10698523. Elder

    PPP2R5C

    PPP2R5C

    PPP2R5C

  • WNT1
  • Protein-coding gene in animals

    (April 2001). "Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway". Molecular Cell. 7 (4):

    WNT1

    WNT1

    WNT1

  • CTNNBIP1
  • Protein-coding gene in humans

    duodenal tumours". Hum. Mol. Genet. 18 (2): 213–26. doi:10.1093/hmg/ddn338. PMID 18854359. Seo E, Jho EH (2007). "Axin-independent phosphorylation of APC controls

    CTNNBIP1

    CTNNBIP1

    CTNNBIP1

  • Ragulator-Rag complex
  • Aspect of cell metabolism

    site for LKB1-mediated AMPK activation by forming the v-ATPase-Ragulator-AXIN/LKB1-AMPK complex. This allows a switch between catabolism and anabolism

    Ragulator-Rag complex

    Ragulator-Rag complex

    Ragulator-Rag_complex

  • Solenoid protein domain
  • Protein domain

    in the RPB1 subunit of RNA polymerase II, or the tandem beta-catenin or axin binding linear motifs in APC (adenomatous polyposis coli). Examples of short

    Solenoid protein domain

    Solenoid protein domain

    Solenoid_protein_domain

  • Secreted frizzled-related protein 1
  • Protein-coding gene in the species Homo sapiens

    3β (GSK3β) and Axin. APC promotes the degradation of β-catenin by increasing the affinity of the degradation complex to β-catenin. Axin is a scaffolding

    Secreted frizzled-related protein 1

    Secreted frizzled-related protein 1

    Secreted_frizzled-related_protein_1

  • CSNK1D
  • Protein-coding gene in humans

    phosphorylate different factors of the pathway, among them Dishevelled (Dvl), Axin, APC, and β-catenin. CK1δ also negatively influences the stability of β-catenin

    CSNK1D

    CSNK1D

    CSNK1D

  • PPP2R5B
  • Protein-coding gene in the species Homo sapiens

    can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin". Oncogene. 19 (4): 537–45. doi:10.1038/sj.onc.1203359. PMID 10698523. Hrimech

    PPP2R5B

    PPP2R5B

    PPP2R5B

  • MAP3K1
  • Protein-coding gene in the species Homo sapiens

    (May 2002). "Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways". The Journal of Biological Chemistry. 277

    MAP3K1

    MAP3K1

    MAP3K1

  • Marnie Blewitt
  • Australian epigeneticist

    (2003). "Transgenerational inheritance of epigenetic states at the murine AxinFu allele occurs following maternal and paternal transmission". Proc Natl

    Marnie Blewitt

    Marnie_Blewitt

  • PPP2CB
  • Enzyme found in humans

    Virology. 238 (2): 432–43. doi:10.1006/viro.1997.8873. PMID 9400615. Hsu W, Zeng L, Costantini F (Feb 1999). "Identification of a domain of Axin that binds

    PPP2CB

    PPP2CB

    PPP2CB

  • RNF111
  • Protein-coding gene in the species Homo sapiens

    Chen M, Li Q, Ye Z, Zhang S, Chan SC, Chen YG, Han J, Lin SC (Apr 2006). "Axin is a scaffold protein in TGF-beta signaling that promotes degradation of

    RNF111

    RNF111

    RNF111

  • SUMO3
  • Protein-coding gene in the species Homo sapiens

    Asashima M, Kikuchi A (June 2002). "Desumoylation activity of Axam, a novel Axin-binding protein, is involved in downregulation of beta-catenin". Molecular

    SUMO3

    SUMO3

    SUMO3

  • Protein tandem repeats
  • in the RPB1 subunit of RNA polymerase II, or the tandem beta-catenin or axin binding linear motifs in APC (adenomatous polyposis coli). The other half

    Protein tandem repeats

    Protein tandem repeats

    Protein_tandem_repeats

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