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Chemical compound
Azepine is an unsaturated heterocycle of seven atoms, with a nitrogen replacing a carbon at one position. The atoms are numbered starting with the nitrogen
Azepine
Yellow chemical compound: building block of many dyes
The Schmidt reaction on anthraquinone gives the lactam, 5H-Dibenz[b,e]azepine-6,11-dione [1143-50-6]. The relevance of this is that it has application
Anthraquinone
Chemical compound
(iminostilbene) is a chemical compound with two benzene rings fused to an azepine ring. Many pharmaceuticals, such as carbamazepine, oxcarbazepine, and depramine
Dibenzazepine
Molecule with one or more rings composed of different elements
analogues with two nitrogen atoms is known as the benzodiazines. For the azepine derivative, benzazepine is the preferred name. Likewise, the compounds
Heterocyclic_compound
Chemical compound
various alkaloid derivatives. The analogue of azepino[4,5-b]indole with the azepine ring fully hydrogenated, noribogaminalog (1,2,3,4,5,6-hexahydroazepino[4
Azepino(4,5-b)indole
Chemical compound
2-Diazepine is a seven-membered heterocyclic compound with two nitrogen atoms (e.g., in ring positions 1 and 2) and three double bonds. Azepine Pubchem v t e
1,2-Diazepine
Antidepressant medication
of this label has been regarded as poor. It is a tetracyclic piperazine-azepine. Mirtazapine has antihistamine, α2-blocker, and antiserotonergic activity
Mirtazapine
Class of chemical compounds
harmala alkaloids. However, ibogalogs have a mostly-hydrogenated 7-membered azepine ring instead of the variably-saturated 6-membered pyridine ring present
Ibogalog
Chemical compound
heterocyclic chemical compounds consisting of a benzene ring fused to an azepine ring. There are three different isomers of benzazepine, including 1-benzazepine
Benzazepine
Chemical compound
glisoxepide, mecillinam, nabazenil, setastine, and tolazamide, among others. Azepine "Hexamethyleneimine". Karsten Eller; Erhard Henkes; Roland Rossbacher;
Azepane
Chemical compound
0]undec-7-ene Names Preferred IUPAC name 2,3,4,6,7,8,9,10-Octahydropyrimido[1,2-a]azepine Other names DBU, Diazabicycloundecene Identifiers CAS Number 6674-22-2 Y
1,8-Diazabicyclo(5.4.0)undec-7-ene
1,8-Diazabicyclo(5.4.0)undec-7-ene
2,4]triazolo[4,3-a]azepine 85687871 Ro13-9868 7.3768 / 42nM 8-chloro-1-methyl-6-phenyl-4H-benzo[f] [1,2,4]triazolo[4,3-a]azepine Ro14-5921 7.7212 / 19nM
List_of_benzodiazepines
Opioid analgesic drug
Ethoheptazine (trade name Zactane) is an opioid analgesic from the phenazepane family. It was invented in the 1950s and is a ring expanded analogue of
Ethoheptazine
Anticonvulsant medication
Kidney (<1%) Identifiers IUPAC name 10,11-dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide CAS Number 28721-07-5 Y PubChem CID 34312 IUPHAR/BPS 7254
Oxcarbazepine
Chemical compound
Vajrodaya, Srumya; Greger, Harald (August 2003). "Insecticidal pyrido[1,2-a]azepine alkaloids and related derivatives from Stemona species". Phytochemistry
Flupyradifurone
Chemical compound
also known as fluoroperlapine, is a morphanthridine (11H-dibenzo[b,e]azepine) atypical antipsychotic with additional antidepressant and sedative effects
Fluperlapine
Anticonvulsant medication
Excretion Urine (72%), feces (28%) Identifiers IUPAC name 5H-dibenzo[b,f]azepine-5-carboxamide CAS Number 298-46-4 Y 85756-57-6 PubChem CID 2554 IUPHAR/BPS
Carbamazepine
Class of toxins
Pinnatoxins are paralytic chemical compounds that inhibit neuronal and muscle-type nicotinic acetylcholine receptors. Although first discovered in shellfish
Pinnatoxin
Index of chemical compounds with the same molecular formula
(molar mass: 93.12 g/mol, exact mass: 93.0578 u) may refer to: Aniline Azepine Methylpyridines (picolines) 2-Methylpyridine 3-Methylpyridine 4-Methylpyridine
C6H7N
Group of alkaloids related to Tabernanthe iboga
distantly related synthetic analogs include: Varenicline, a polycyclic azepine and anti-addictive agent that similarly targets nicotinic acetylcholine
Iboga-type_alkaloid
Molecule with a ring of bonded atoms
shown, and delocalized π-electrons shown as discrete bonds (aromatic). Azepine, a 7-membered heterocyclic organic compound (non-aromatic). The following
Cyclic_compound
Antidepressant
IUPAC name (±)-2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine CAS Number 24219-97-4 Y 21535-47-7 (hydrochloride) 51152-88-6 ((S)-isomer)
Mianserin
Canadian federal drug regulation act
propionate) but not including: Ethoheptazine (ethyl hexahydro-1-methyl-4-phenyl-azepine-4-carboxylate) and its salts Metethoheptazine (ethyl hexahydro-1
Controlled Drugs and Substances Act
Controlled_Drugs_and_Substances_Act
Antidepressant
10075-24-8. The parent compound of imipramine, 10,11-dihydro-5H-dibenz[b,f]azepine (dibenzazepine), was first synthesized in 1899, but no pharmacological
Imipramine
Pharmaceutical compound
THAZ, also known as 5,6,7,8-tetrahydro-4H-isoxazolo(4,5-d)azepin-3-ol, is a moderately potent GABAA-ρ receptor antagonist related to gaboxadol (THIP).
THAZ
Chemical compound
of substituents or nearby cations strongly influences the conformation. Azepine Pyrrole Cyclononatetraene (2Z,4Z,6Z,8Z)-Thionine Oxonine Somers, K. R.
Azonine
Subtype of serotonin receptor
effects of serotonergic psychedelics. 2-Alkyl-4-aryl-tetrahydro-pyrimido-azepines – subtype selective antagonists (35 g: 60-fold). 5-MeO-NBpBrT AMDA and
5-HT2A_receptor
Dipolar compound
B. A. (2013). "[1,7]-Electrocyclization reactions in the synthesis of azepine derivatives". Chemistry of Heterocyclic Compounds. 49 (1): 152–176. doi:10
Azomethine_ylide
Incapacitating gas used in riot control
Qiang; Sun, Ping-Hua (2010). "Molecular Modeling Studies on 11H-Dibenz[b,e]azepine and Dibenz[b,f][1,4]oxazepine Derivatives as Potent Agonists of the Human
CR_gas
Chemical compound
Identifiers IUPAC name 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepine-3-carbonitrile CAS Number 66834-24-0 PubChem CID 48126 ChemSpider 43782
Cianopramine
Chemical compound
at one position and with an oxygen replacing a carbon at one position. Azepine Benzazepines Diazepine Oxepin Borepin CR gas (dibenzoxazepine) Katritzky
Oxazepine
Chemical compound
R07AB03 (WHO) Identifiers IUPAC name 6,7,8,9-tetrahydro-5H-tetrazolo(1,5-a)azepine CAS Number 54-95-5 Y PubChem CID 5917 ChemSpider 5704 N UNII WM5Z385K7T
Pentylenetetrazol
Pharmaceutical compound
Balinatunfib (SAR441566) is an experimental drug which acts as a potent small molecule inhibitor of TNF. Rather than blocking TNF receptors, balinatunfib
Balinatunfib
Serotonin receptor protein distributed mainly in the choroid plexus
"Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT₂C) receptor agonists with exquisite
5-HT2C_receptor
Chemical compound
N-diethylaminoborane (2) gives 10-borohydro-5-methyl-10,11-dihydro-dibenzo[b,f]azepine (3). This is treated with methylchloramine (4), completing the synthesis
Metapramine
Spanish chemist
Carbene Complexes and α,β-Unsaturated Imine Derivatives: Synthesis of Azepines and Mechanistic NMR Studies". Chemistry: A European Journal. 2: 88–97.
José_Barluenga
Chemical compound
receptor agonist PNU-22394A (3) resulted in weight loss [22,23]. [...] 3.4 Azepine and diazepnes: In the 1960s, Upjohn evaluated indolylazepine U-22394A (compound
PNU-22394
Chemical compound
PMID 28894119. O'Hagan, David (1997). "Pyrrole, pyrrolidine pyridine, piperidine, azepine and tropane alkaloids". Natural Product Reports (Review). 14 (6): 637.
Solenopsin
Class of chemical compounds
"Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT₂C) receptor agonists with exquisite
Substituted_3-benzazepine
(compound 4d) 3-phenylmethoxy-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine (245) 71562661 ? UCD0179 (4-desmethylene-LSD; compound 11 or formula IIa)
List of miscellaneous 5-HT2A receptor agonists
List_of_miscellaneous_5-HT2A_receptor_agonists
Chemical compound
3,5,6,7,8-hexahydro-9-nitro-5,8-Epoxy-1H-imidazo[1,2-a]azepine Identifiers CAS Number 1203791-41-6 3D model (JSmol) Interactive image
Cycloxaprid
as the triflate and the amine group as the mesylate for intramolecular azepine ring closure via nucleophilic substitution (with 6% epimer formation).
Galantamine_total_synthesis
Anticonvulsant medication
renal Identifiers IUPAC name (S)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide CAS Number 236395-14-5 PubChem CID 179344 DrugBank DB09119
Eslicarbazepine_acetate
Class of chemical substances
O. Plunkett (1994), "Pyrrole, pyrrolidine, pyridine, piperidine, and azepine alkaloids", Natural Product Reports, vol. 11, no. 6, p. 581, doi:10.1039/np9941100581
Pyridines
Chemical compound
Iminodibenzyl Names Other names 10,11-Dihydro-5H-dibenzo[b,f]azepine Identifiers 3D model (JSmol) Interactive image ChEMBL ChEMBL63054 ChemSpider 9886
Iminodibenzyl
Pharmaceutical compound
N-Bn-THAZ is a selective agonist of the serotonin 5-HT2A and 5-HT2C receptors. It is a derivative of THAZ, which itself is a weak antagonist of the glycine
N-Bn-THAZ
Protein found in humans
Rivers DA, Stean TO, Stemp G, Trail BK, Witty DR (October 2008). "Tricyclic azepine derivatives as selective brain penetrant 5-HT6 receptor antagonists". Bioorganic
5-HT6_receptor
example, a 7-membered mancude ring system has three double bonds in it (e.g. azepine, oxepine, ...). 脒 amidine 米 mǐ 'rice' mǐ European pronunciation 咪唑 imidazole
Organic nomenclature in Chinese
Organic_nomenclature_in_Chinese
Nitrogen-based molecule
azides in diethylamine. Formation and autoxidation of 2-diethylamino-1H-azepine intermediates". Journal of the American Chemical Society. 94 (2): 513–520
Nitrene
Chemical compound
3,4,5-tetrahydro-2H-benzo[c]azepine-2-carbothioamide N-(4-Chlorophenethyl)-7,8-dihydroxy-4,5-dihydro-1H-benzo[c]azepine-2(3H)-carbothioamide Identifiers
Capsazepine
Investigational dopamine antagonist
8,9,13b-Hexahydro-3-chloro-2-hydroxy-N-methyl-5H-benzo[d]naptho-(2,1-b)azepine CAS Number 112108-01-7 Y PubChem CID 107930 IUPHAR/BPS 3304 ChemSpider
Ecopipam
Alkaloid isolated from a marine sponge
Stevensine is a bromopyrrole alkaloid originally isolated from an unidentified Micronesian marine sponge, as well as the known sponge species, Pseudaxinyssa
Stevensine
Pharmaceutical compound
4-Allyl-6-oxa-noribogainalog is a κ-opioid receptor (KOR) agonist of the oxa-ibogalog family related to oxa-noribogaine. It is a highly potent full agonist
4-Allyl-6-oxa-noribogainalog
Organic chemical transformation
(9) Divinyl aziridines undergo a similar suite of reactions providing azepines or vinyl pyrrolines depending on the relative configuration of the aziridine
Divinylcyclopropane-cycloheptadiene rearrangement
Divinylcyclopropane-cycloheptadiene_rearrangement
Drug class
; Ward, R. V.; Westbrook, D.; Whitlock, G. A. (2011). "Pyrimido\4,5-d]azepines as potent and selective 5-HT2C receptor agonists: Design, synthesis, and
5-HT2C_receptor_agonist
Pair of enantiomers
Identifiers IUPAC name (RS)-3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine CAS Number 80012-43-7 Y PubChem CID 3241 IUPHAR/BPS 7176 DrugBank DB00751 Y
Epinastine
many times the molecule can be cycled without degrading. Various ketones, azepines and norbornadienes among other compounds, such as azobenzene and its derivatives
Solar_chemical
Chemical compound
Bernstein PR, Wu Y, Urbanek RA, Becker CW, Throner SR, et al. (January 2013). "Azepines and piperidines with dual norepinephrine dopamine uptake inhibition and
Osanetant
Chemical compound
10aR)-5a,6,9,10-Tetrahydro,7H,11H-8,10a-methanopyrido[2',3':5,6]pyrano[2,3-d]azepine CAS Number 292634-27-6 Y PubChem CID 9816447 ChemSpider 8352269 N UNII
Dianicline
Fungi of Aotearoa
host species Pinus radiata. Their peppery taste has been attributed to 2H-azepines chalciporone 66 found within the fruiting body. Pepper Boletes are thought
Fungi_of_New_Zealand
The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)
List_of_MeSH_codes_(D03)
Israeli organic chemist (1930–2024)
azirines, azetines, as well as of larger ring heterocycles including azepines. Recently they studied TiCl 4 {\displaystyle _{4}} catalyzed reactions
Alfred_Hassner
Chemical compound
Tabernanthine is an alkaloid found in Tabernanthe iboga. It has been used in laboratory experiments to study how addiction affects the brain. Tabernanthine
Tabernanthine
Chemical compound
name 1-benzyl-3-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-pyrazolo[3,4-d]azepine CAS Number 851373-91-6 PubChem CID 11151899 ChemSpider 9327007 UNII 28PGH5X4OQ
JNJ-18038683
Chemical compound
xy)phenethyl)piperidin-4ylidene)-6,11-dihydro-5H-benzo[d]imidazo[1,2-a]azepine-3-carboxylate and its free base form has a chemical formula of C37H36N4O3
Laniquidar
Active metabolite of oxcarbazepine
renal Identifiers IUPAC name (RS)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide CAS Number 29331-92-8 PubChem CID 114709 ChemSpider 102704
Licarbazepine
Pharmaceutical compound
Other names Luvion; 2-Bromo-6-methylergoline-8β-methanol hexahydro-1H-azepine-1-carboxylate Drug class Sympatholytic; Antihypertensive; Vasodilator ATC
Brazergoline
Chemical compound
"Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT2C) receptor agonists with exquisite
PF-04479745
Chemical compound
(6S)-Hexahydro-6-[(αS)-α-mercaptohydrocinnamido]-2,2-dimethyl-7-oxo-1H-azepine-1-acetic acid CAS Number 160135-92-2 PubChem CID 9886079 ChemSpider 8061752
Gemopatrilat
Chemical compound
Identifiers IUPAC name 3-(piperazin-1-yl)-9H-dibenzo[c,f][1,2,4]triazolo[4,3-a]azepine CAS Number 90685-01-1 Y PubChem CID 146222 ChemSpider 128982 UNII 4KHA9U8INV
Pitrazepin
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