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AZTREONAM

  • Aztreonam
  • Chemical compound

    Aztreonam, sold under the brand name Azactam among others, is an antibiotic used primarily to treat infections caused by gram-negative bacteria such as

    Aztreonam

    Aztreonam

    Aztreonam

  • Aztreonam/avibactam
  • Combination antibiotic medication

    Aztreonam/avibactam, sold under the brand name Emblaveo, is a fixed-dose combination antibacterial medication used for the treatment of aerobic Gram-negative

    Aztreonam/avibactam

    Aztreonam/avibactam

    Aztreonam/avibactam

  • Avibactam
  • Chemical compound

    avibactam as companion drug administered alongside aztreonam. In fact, although in theory aztreonam is not hydrolyzed by metallo-β-lactamases, many

    Avibactam

    Avibactam

    Avibactam

  • Gram-negative bacteria
  • Group of bacteria that do not retain the Gram stain used in bacterial differentiation

    gram-negative bacteria include aminoglycosides, monobactams (such as aztreonam), and ciprofloxacin. Conventional gram-negative (LPS-diderm) bacteria

    Gram-negative bacteria

    Gram-negative bacteria

    Gram-negative_bacteria

  • List of β-lactam antibiotics
  • Imipenem Meropenem Panipenem Razupenem Tebipenem pivoxil Thienamycin Aztreonam Tigemonam Nocardicin A Tabtoxinine β-lactam (does not inhibit penicillin-binding

    List of β-lactam antibiotics

    List of β-lactam antibiotics

    List_of_β-lactam_antibiotics

  • Timeline of antibiotics
  • imipenem/cilastatin, the first carbapenem 1985 – ofloxacin 1986 – mupirocin 1986 – aztreonam 1986 – cefoperazone/sulbactam 1986 – co-ticarclav (ticarcillin/clavulanic

    Timeline of antibiotics

    Timeline_of_antibiotics

  • Monobactam
  • Monocyclic β-lactam antibiotics

    disrupting the patient's microbiota. Monobactams are nevertheless seldom used. Aztreonam is the archetypal monobactam. Other monobactams include tigemonam, nocardicin

    Monobactam

    Monobactam

    Monobactam

  • AZT (disambiguation)
  • Topics referred to by the same term

    HIV/AIDS. AZT or azt may also refer to: Azerbaijan Time, a time zone Aztreonam, an antibiotic drug Atta language's ISO 639 code This disambiguation page

    AZT (disambiguation)

    AZT_(disambiguation)

  • Septic shock
  • Dangerously low blood pressure due to damage from an organ infection

    or carbapenem. If the patient has a beta lactam allergy one can give aztreonam and a fluoroquinolone. Vancomycin should be added in the cases of empyema

    Septic shock

    Septic shock

    Septic_shock

  • Cystic fibrosis
  • Genetic disorder affecting mostly the lungs

    Port-a-Cath. Inhaled therapy with antibiotics such as tobramycin, colistin, and aztreonam is often given for months at a time to improve lung function by impeding

    Cystic fibrosis

    Cystic fibrosis

    Cystic_fibrosis

  • List of antibiotics
  • particularly levofloxacin, ciprofloxacin Polymyxins: Colistin, Polymyxin B Aztreonam (monobactam) Aminoglycosides - particularly tobramycin and amikacin Antibiotics

    List of antibiotics

    List_of_antibiotics

  • Beta-lactamase
  • Class of enzymes

    cefotaxime, ceftriaxone, and ceftazidime, as well as the oxyimino-monobactam aztreonam), but not 7-alpha-methoxy-cephalosporins (cephamycins; in other words

    Beta-lactamase

    Beta-lactamase

    Beta-lactamase

  • Burkholderia cepacia complex
  • Species of bacterium

    effectiveness of long-term antibiotic treatment with continuous inhaled aztreonam lysine (AZLI) in terms of lung function or chest infections. B. cepacia

    Burkholderia cepacia complex

    Burkholderia cepacia complex

    Burkholderia_cepacia_complex

  • Proteus penneri
  • Species of bacterium

    macrolides, but are naturally sensitive to aminoglycosides, carbapenems, aztreonam, quinolones, sulphamethoxazole, and co-trimoxazole. Isolates of P. penneri

    Proteus penneri

    Proteus penneri

    Proteus_penneri

  • Amoxicillin/clavulanic acid
  • Combination antibiotic medication

    broad-spectrum antibiotics. Combining amoxicillin/clavulanic acid with aztreonam can further enhance its activity against certain resistant UTI-causing

    Amoxicillin/clavulanic acid

    Amoxicillin/clavulanic acid

    Amoxicillin/clavulanic_acid

  • Disk diffusion test
  • Type of microbiology test

    in vitro efficacy of ceftazidime/avibactam (primary disks) in terms of aztreonam (secondary disks). Disk diffusion method can be used to test susceptibility

    Disk diffusion test

    Disk diffusion test

    Disk_diffusion_test

  • Gilead Sciences
  • American pharmaceutical company

    signaled Gilead's entry into the respiratory arena. Corus was developing aztreonam lysine for the treatment of patients with cystic fibrosis who are infected

    Gilead Sciences

    Gilead Sciences

    Gilead_Sciences

  • Benzathine benzylpenicillin
  • Antibiotic

    Siderophore Cefiderocol# Veterinary Ceftiofur Cefquinome Cefovecin Monobactams Aztreonam Tigemonam‡ Carumonam‡ Nocardicin A‡ β-lactamase inhibitors Penam (Sulbactam

    Benzathine benzylpenicillin

    Benzathine benzylpenicillin

    Benzathine_benzylpenicillin

  • Élan
  • Irish pharmaceutical company

    (ziconotide) NANOCRYSTAL technology In pipeline: TYSABRI (natalizumab) AZACTAM (aztreonam for injection, USP) MAXIPIME (cefepime hydrochloride) for Injection Revenue

    Élan

    Élan

    Élan

  • Bristol Myers Squibb
  • American pharmaceutical company

    disoproxil fumarate) – comarketed with Gilead Sciences Azactam (aztreonam) Baraclude (entecavir) Daklinza (daclatasvir) Evotaz (atazanavir/cobicistat)

    Bristol Myers Squibb

    Bristol Myers Squibb

    Bristol_Myers_Squibb

  • Ceftazidime
  • Antibiotic medication

    water-solubility. Ceftazidime shares the same variable R-group side chain with aztreonam, a monobactam antibiotic; the two drugs share a similar spectrum of activity

    Ceftazidime

    Ceftazidime

    Ceftazidime

  • Pseudomonas aeruginosa
  • Species of bacterium

    but not ertapenem) polymyxins (polymyxin B and colistin) monobactams (aztreonam) As fluoroquinolones are one of the few antibiotic classes widely effective

    Pseudomonas aeruginosa

    Pseudomonas aeruginosa

    Pseudomonas_aeruginosa

  • Karen Bush
  • American biochemist

    leads to clinical trials and 5 antibiotics to FDA and/or EMA approval (aztreonam, piperacillin-tazobactam, levofloxacin, doripenem and ceftobiprole). As

    Karen Bush

    Karen Bush

    Karen_Bush

  • Schedule H
  • Class of prescription drugs in India

    INJECTION 42. ATORVASTATIN CALCIUM 43. AURANOFIN 44. AZATHIOPRINE 45. AZTREONAM 46. BACAMPICILLIN 47. BACLOFEN 48. BALSALAZIDE 49. BAMBUTEROL 50. BARBITURIC

    Schedule H

    Schedule_H

  • Nacubactam
  • Chemical compound

    combination with other β-lactam antibiotics such as meropenem, cefepime, and aztreonam for the treatment of complicated urinary tract infections and other serious

    Nacubactam

    Nacubactam

    Nacubactam

  • Richard Sykes (microbiologist)
  • British microbiologist (born 1942)

    by the Squibb Institute, in the United States, where he then developed aztreonam, the first clinically effective monobactam, a term he coined in 1981 to

    Richard Sykes (microbiologist)

    Richard_Sykes_(microbiologist)

  • Ceftazidime/avibactam
  • Combination antibiotic medication

    (December 2017). "New Delhi Metallo-β-Lactamase 1 Catalyzes Avibactam and Aztreonam Hydrolysis". Antimicrob. Agents Chemother. 61 (12) e01224-17. doi:10.1128/AAC

    Ceftazidime/avibactam

    Ceftazidime/avibactam

    Ceftazidime/avibactam

  • Bronchiectasis
  • Permanent enlargement of the lung airways

    antibiotics include aerosolized tobramycin, inhaled ciprofloxacin, aerosolized aztreonam, and aerosolized colistin. However, there arises a problem with inhaled

    Bronchiectasis

    Bronchiectasis

    Bronchiectasis

  • Enterococcus faecalis
  • Species of bacterium

    resistant to many commonly used antimicrobial agents (aminoglycosides, aztreonam and quinolones). The resistance is mediated by the presence of multiple

    Enterococcus faecalis

    Enterococcus faecalis

    Enterococcus_faecalis

  • Β-Lactamase inhibitor
  • Drugs that inhibit β-Lactamase enzymes

    Avibactam, approved in combination with ceftazidime (Avycaz, Zavicefta) and aztreonam (Emblaveo), currently undergoing clinical trials for combination with

    Β-Lactamase inhibitor

    Β-Lactamase inhibitor

    Β-Lactamase_inhibitor

  • Cefepime/sulbactam
  • Combination antibiotics

    Combination therapy: Synergistic effects observed with amikacin and aztreonam against P. aeruginosa and A. baumannii. New β-lactamase inhibitors: LN-1-255

    Cefepime/sulbactam

    Cefepime/sulbactam

  • Ceftobiprole
  • Chemical compound

    ceftobiprole medocaril (192 participants) or daptomycin plus optional aztreonam [the comparator] (198 participants). The primary measure of efficacy for

    Ceftobiprole

    Ceftobiprole

    Ceftobiprole

  • Raman spectroscopy
  • Spectroscopic technique

    polymorphic forms, if more than one exist. For example, the drug Cayston (aztreonam), marketed by Gilead Sciences for cystic fibrosis, can be identified and

    Raman spectroscopy

    Raman spectroscopy

    Raman_spectroscopy

  • Side effects of penicillin
  • Siderophore Cefiderocol# Veterinary Ceftiofur Cefquinome Cefovecin Monobactams Aztreonam Tigemonam‡ Carumonam‡ Nocardicin A‡ β-lactamase inhibitors Penam (Sulbactam

    Side effects of penicillin

    Side_effects_of_penicillin

  • Ecthyma gangrenosum
  • Medical condition

    aminoglycosides, fluoroquinolones, third-generation cephalosporins, or ceftriaxone aztreonam can be given. Usually, the antibiotics are changed according to the culture

    Ecthyma gangrenosum

    Ecthyma gangrenosum

    Ecthyma_gangrenosum

  • Ceftaroline fosamil
  • Chemical compound

    reported non-inferior efficacy against MRSA compared to vancomycin and aztreonam. In 2009, ceftaroline had completed phase-III clinical trials for community-acquired

    Ceftaroline fosamil

    Ceftaroline fosamil

    Ceftaroline_fosamil

  • Vancomycin
  • Antibiotic medication

    (March 2015). "Inhaled antibiotics beyond aminoglycosides, polymyxins and aztreonam: A systematic review". Int J Antimicrob Agents. 45 (3): 221–33. doi:10

    Vancomycin

    Vancomycin

    Vancomycin

  • Delafloxacin
  • Chemical compound

    by the FDA in June 2017, after it was noninferior to vancomycin plus aztreonam in two trials on 1042 patients with acute bacterial skin and skin structure

    Delafloxacin

    Delafloxacin

    Delafloxacin

  • Multiple drug resistance
  • Measure of microorganism drug resistance

    harbouring four amino acid inserts in PBP3 adversely impacting activity of aztreonam/avibactam". Journal of Antimicrobial Chemotherapy. 75 (6): 1650–1651.

    Multiple drug resistance

    Multiple drug resistance

    Multiple_drug_resistance

  • Carumonam
  • Chemical compound

    its class, Carumonam was withdrawn sometime before 2021, leaving only Aztreonam on the market. It is very resistant to beta-lactamases, which means that

    Carumonam

    Carumonam

    Carumonam

  • Chromobacterium violaceum
  • Species of bacterium

    ocular infection. C. violaceum produces a number of natural antibiotics: Aztreonam is a monobactam antibiotic that is active against gram-negative aerobic

    Chromobacterium violaceum

    Chromobacterium violaceum

    Chromobacterium_violaceum

  • Haverhill fever
  • Medical condition

    susceptible to a number of antibiotics. They are: cephalosporins, carbapenems, aztreonam, clindamycin, erythromycin, nitrofurantoin, bacitracin, doxycycline, tetracycline

    Haverhill fever

    Haverhill fever

    Haverhill_fever

  • Cerebral shunt
  • Surgical implant to treat hydrocephalus

    although the efficacy of the aminoglycosides is not clear. Meropenem and aztreonam are additional antibiotic options that are effective against gram-negative

    Cerebral shunt

    Cerebral shunt

    Cerebral_shunt

  • Cardiobacterium valvarum
  • Species of bacterium

    to beta-lactam, trimethoprim-sulfamethoxazole, fluoroquinolones, and aztreonam. Current clinical guidelines recommend that C. valvarum infection be treated

    Cardiobacterium valvarum

    Cardiobacterium_valvarum

  • Jeffrey Feltner
  • American serial killer

    Feltner's AIDS had been getting progressively worse despite treatment with Aztreonam. As a result of this, he died on March 17, 1993. List of serial killers

    Jeffrey Feltner

    Jeffrey_Feltner

  • ATC code J01
  • Pharmaceutical drug classification

    beta-lactamase inhibitor QJ01DE90 Cefquinome J01DF01 Aztreonam J01DF02 Carumonam J01DF51 Aztreonam and beta-lactamase inhibitor J01DH02 Meropenem J01DH03

    ATC code J01

    ATC_code_J01

  • Ampicillin/sulbactam
  • Combination antibiotic drug

    Siderophore Cefiderocol# Veterinary Ceftiofur Cefquinome Cefovecin Monobactams Aztreonam Tigemonam‡ Carumonam‡ Nocardicin A‡ β-lactamase inhibitors Penam (Sulbactam

    Ampicillin/sulbactam

    Ampicillin/sulbactam

  • 2-Aminothiazole
  • Chemical compound

    examples are abafungin, acotiamide, amiphenazole, amthamine, avatrombopag, aztreonam, cefepime, cefixime, ceftizoxime, ceftiofur, ceftibuten, cefpirome, famotidine

    2-Aminothiazole

    2-Aminothiazole

    2-Aminothiazole

  • Epicillin
  • Chemical compound

    Siderophore Cefiderocol# Veterinary Ceftiofur Cefquinome Cefovecin Monobactams Aztreonam Tigemonam‡ Carumonam‡ Nocardicin A‡ β-lactamase inhibitors Penam (Sulbactam

    Epicillin

    Epicillin

    Epicillin

  • Tigecycline
  • Chemical compound

    III trials in which it was at least equal to intravenous vancomycin and aztreonam to treat complicated skin and skin structure infections, and to intravenous

    Tigecycline

    Tigecycline

    Tigecycline

  • Elizabethkingia
  • Genus of bacteria

    intrinsic resistance to most β-lactam antibiotics, including carbapenems and aztreonam, but it may remain susceptible to piperacillin and piperacillin/tazobactam

    Elizabethkingia

    Elizabethkingia

  • Ventilator-associated pneumonia
  • Pneumonia due to use of ventilator

    beta-lactam antibiotics such as ampicillin. Resistance to cephalosporins and aztreonam may arise through induction of a plasmid-based extended spectrum beta-lactamase

    Ventilator-associated pneumonia

    Ventilator-associated pneumonia

    Ventilator-associated_pneumonia

  • Cefozopran
  • Chemical compound

    Siderophore Cefiderocol# Veterinary Ceftiofur Cefquinome Cefovecin Monobactams Aztreonam Tigemonam‡ Carumonam‡ Nocardicin A‡ β-lactamase inhibitors Penam (Sulbactam

    Cefozopran

    Cefozopran

    Cefozopran

  • Pathogenic Escherichia coli
  • Strains of E. coli that can cause disease

    as other semisynthetic penicillins, many cephalosporins, carbapenems, aztreonam, trimethoprim-sulfamethoxazole, ciprofloxacin, nitrofurantoin and the

    Pathogenic Escherichia coli

    Pathogenic Escherichia coli

    Pathogenic_Escherichia_coli

  • List of MeSH codes (D02)
  • MeSH D02.065.589.099.500 – monobactams MeSH D02.065.589.099.500.044 – aztreonam MeSH D02.065.589.099.625 – moxalactam MeSH D02.065.589.099.750 – penicillins

    List of MeSH codes (D02)

    List_of_MeSH_codes_(D02)

  • List of drugs: As–Az
  • Gantanol Azo Gantrisin Azolid azolimine (INN) Azopt azosemide (INN) azotomycin (INN) azoximer bromide (INN) aztreonam (INN) Azulfidine azumolene (INN)

    List of drugs: As–Az

    List_of_drugs:_As–Az

  • Health in Nepal
  • Ampicillin 100 Amoxicilin 100 Cefixime 100 Ceftazidime 100 Ceftriaxone 100 Aztreonam 100 Cephalexin 92 Ciprofloxacin 78 Tigecycline 0 Colistin 0 E.coli (MDR)

    Health in Nepal

    Health_in_Nepal

  • Bordetella avium
  • Species of bacterium

    resistance to a number of antibiotics. Resistance has been elucidated to aztreonam, ampicillin, tetracycline, cephalosporins, penicillins, sulbactam, sulfonamides

    Bordetella avium

    Bordetella_avium

  • Claire Wainwright
  • Australian paediatric respiratory physician

    Nakamura C, Wooldridge JL, Gibson RL, Lewis S, Montgomery AB (July 2011). "Aztreonam for Inhalation Solution (AZLI) in Patients with Cystic Fibrosis, Mild

    Claire Wainwright

    Claire_Wainwright

  • List of MeSH codes (D03)
  • caprolactam MeSH D03.383.411.350 – monobactams MeSH D03.383.411.350.044 – aztreonam MeSH D03.383.411.500 – moxalactam MeSH D03.383.517.200 – carboxin MeSH D03

    List of MeSH codes (D03)

    List_of_MeSH_codes_(D03)

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