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Protein-coding gene in the species Homo sapiens
BCL2-interacting killer is a protein that in humans is encoded by the BIK gene. The protein encoded by this gene is known to interact with cellular and
BCL2-interacting_killer
Protein-coding gene in the species Homo sapiens
homologous antagonist/killer is a protein which in humans is encoded by the BAK1 gene on chromosome 6. It belongs to the BCL2 protein family. BCL2 family members
Bcl-2 homologous antagonist killer
Bcl-2_homologous_antagonist_killer
Protein found in humans
the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins. BCL2 blocks programmed cell death (apoptosis) while other BCL2 family
Bcl-2
Mammalian protein found in Homo sapiens
protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of
Apoptosis_regulator_BAX
Protein-coding gene in the species Homo sapiens
shorter form (Bcl-xS) acts as an apoptotic activator. BCL2-like 1 (gene) has been shown to interact with: APAF1, BAK1, BCAP31, BCL2L11, BNIP3, BNIPL, BAD
Bcl-2-like_protein_1
Protein-coding gene in the species Homo sapiens
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 is a protein found in humans that is encoded by the BNIP3 gene. BNIP3 is a member of the apoptotic
BNIP3
Protein-coding gene in the species Homo sapiens
Bcl-2-related ovarian killer (Bok) was identified in a yeast two-hybrid experiment with a rat ovarian cDNA library in a screen for proteins interacting with Mcl-1
BOK_(gene)
Medical condition
induces infected cells to overexpress genes that produce cMyc, NF-κB, and BCL2 proteins which when overexpressed block these cells' apoptosis (i.e. cell
Extranodal NK/T-cell lymphoma, nasal type
Extranodal_NK/T-cell_lymphoma,_nasal_type
Protein-coding gene in the species Homo sapiens
PMID 15302935. Kumar R, Lutz W, Frank E, Im HJ (2004). "Immediate early gene X-1 interacts with proteins that modulate apoptosis". Biochem. Biophys. Res. Commun
Large proline-rich protein BAG6
Large_proline-rich_protein_BAG6
Study of the role of the immune system in cancer
PMID 32466293. Frenzel A, Grespi F, Chmelewskij W, Villunger A (April 2009). "Bcl2 family proteins in carcinogenesis and the treatment of cancer". Apoptosis
Cancer_immunology
Mammalian protein found in humans
After the CCL5/CCR5 binding, some other proteins are regulated as well. Bcl2 is more expressed and it induces apoptosis. Beta-catenin is phosphorylated
CCL5
Protein-coding gene in the species Homo sapiens
therapies. Apoptosis Apoptosome Bcl-2 Bcl-2-associated X protein (BAX) BH3 interacting domain death agonist (BID) Caspases Cytochrome c Noxa Mitochondrion GRCh38:
P53 upregulated modulator of apoptosis
P53_upregulated_modulator_of_apoptosis
Type of gene used for anticancer
through Bax-mediated mitochondrial-dysfunction through the inhibition of the Bcl2 family's antiapoptotic members. Through gene knockout studies, it was shown
Anticancer_gene
Biological signaling pathway h
role in this process, as it can allow the transcription of genes such as BCL2 and c-Myc, which are involved in cell division. Mutations in JAK2 can lead
JAK-STAT_signaling_pathway
Form of programmed cell death
disease, in particular cancer. This occurred in 1988 when it was shown that BCL2, the gene responsible for follicular lymphoma, encoded a protein that inhibited
Apoptosis
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BCL2 INTERACTING-KILLER
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