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Protein-coding gene in humans
ubiquitin-protein ligase that in humans is encoded by the CBLB gene. CBLB is a member of the CBL gene family. CBL-B functions as a negative regulator of T-cell
CBLB_(gene)
Topics referred to by the same term
CBLB may refer to: CBLB (gene) CBLB (AM), a radio retransmitter (1340 AM) licensed to serve Schreiber, Ontario, Canada This disambiguation page lists
CBLB
Protein-coding gene in the species Homo sapiens
methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. GRCh38: Ensembl
MMAB
Human chromosome
cblB type MON2: encoding protein Protein MON2 homolog MUCL1: encoding protein Mucin-like protein 1 MYO1A: myosin IA NANOG: NK-2 type homeodomain gene
Chromosome_12
Protein-coding gene in the species Homo sapiens
of genotype and biochemical data in 32 patients belonging to mut, cblA or cblB complementation group". J. Inherit. Metab. Dis. 31 (1): 55–66. doi:10
MMAA
Psychoactive component of cannabis
Omburo SN, Soto-Fuentes W, He J, et al. (2009). "Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa".
Tetrahydrocannabinol
Protein family
BARD1, BBAP, BFAR, BIRC2, BIRC3, BIRC7, BIRC8, BMI1, BRAP, BRCA1, CBL, CBLB, CBLC, CBLL1, CHFR, CNOT4, COMMD3, DTX1, DTX2, DTX3, DTX3L, DTX4, DZIP3,
RING_finger_domain
Medical condition
isoleucine, threonine, methionine, and valine without causing an attack. CblA und cblB versions of methylmalonic acidemia are cobalamin-responsive.[citation needed]
Methylmalonic_acidemias
Transmembrane protein
factor receptor has been shown to interact with: AR, ARF4, CAV1, CAV3, CBL, CBLB, CBLC, CD44, CDC25A, CRK, CTNNB1, DCN, EGF, GRB14, Grb2, JAK2, MUC1, NCK1
Epidermal growth factor receptor
Epidermal_growth_factor_receptor
"Statistics & download files". www.genenames.org. HUGO Gene Nomenclature Committee. 3 November 2025. Retrieved 3 November 2025.
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Protein-coding gene in the species Homo sapiens
gene, Arachidonate 5-lipoxygenase, B-cell linker, BCAR1, BCR gene, Beta-2 adrenergic receptor, C-Met, CBLB, CD117, CD22, CD28, CDKN1B, CRK, Cbl gene,
GRB2
Human protein encoding gene
enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB". PLOS Pathogens. 14 (7) e1007111. doi:10.1371/journal.ppat.1007111. PMC 6053247
C2orf72
Protein-coding gene in the species Homo sapiens
to SHORT syndrome. PIK3R1 has been shown to interact with: ADAM12, BCAR1, CBLB, CD117, CD28, CD7, CENTG1, CBL, EPHA2, EPOR, ERBB3, EZR, FCGR2A, GAB1, GAB2
PIK3R1
Rare metabolic disease
disorder caused by homozygous or compound heterozygous variants in the ACSF3 gene. This results in a defect of the mitochondrial enzyme acyl-CoA synthetase
Combined malonic and methylmalonic aciduria
Combined_malonic_and_methylmalonic_aciduria
Protein-coding gene in the species Homo sapiens
of DAB1. CRKL has been shown to interact with: Abl gene, BCAR1, BCR gene, CBLB, CD117, CD34, Cbl gene, Dock2, EPOR, GAB1, GAB2, INPP5D, MAP4K1, MAP4K5,
CRKL
Protein-coding gene in the species Homo sapiens
SH3GLB2, SH3GL3, SH3GL2, BCAR1, Epidermal growth factor receptor, CBLB, Cbl gene, SOS1, CRK and PAK2. GRCh38: Ensembl release 89: ENSG00000147010 – Ensembl
SH3KBP1
Form of cancer immunotherapy
intrinsic regulators include molecules with ubiquitin ligase activity, including CBLB, and CISH. More recently, CISH (cytokine-inducible SH2-containing protein)
Checkpoint_inhibitor
Psychoactive drug from the cannabis plant
Publishing. pp. 12. ISBN 978-1-878823-23-6. Richer, Alanna Durkin; Johnson, Gene (23 April 2026). "Trump reclassifies state-licensed medical marijuana as
Cannabis_(drug)
Protein-coding gene in the species Homo sapiens
enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB". PLoS Pathogens. 14 (7): 55–67. doi:10.1371/journal.ppat.1007111. PMC 6053247
Apolipoprotein_L2
Proposed mechanism of cannabis compounds
Dominik (2022). "Analysis of Morphological Traits, Cannabinoid Profiles, THCAS Gene Sequences, and Photosynthesis in Wide and Narrow Leaflet High-Cannabidiol
Entourage_effect
Protein-coding gene in humans
reported to be involved in activation of MAPK signaling. E3 ubiquitin ligase CBLB has been described as negative regulator of dectin-2. Dectin-2 is known to
CLEC6A
THC precursor
show a significant increased cytotoxic activity and suppress COX-2 and MMP9 gene expression in both cell culture and colon tissue, suggest the anti-inflammatory
Tetrahydrocannabinolic_acid
Chemical compound (fatty acid neurotransmitter)
glutamatergic neurons independently of corticotropin-releasing hormone signaling". Genes, Brain and Behavior. 8 (2): 203–211. doi:10.1111/j.1601-183X.2008.00463
Anandamide
Medical therapy involving transplant of cells expanded ex vivo
intrinsic regulators include molecules with ubiquitin ligase activity, including CBLB. More recently, CISH, a molecule with ubiquitin ligase activity, was found
Adoptive_cell_transfer
Phytocannabinoid discovered in 1940
Omburo SN, Soto-Fuentes W, He J, et al. (2009). "Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa".
Cannabidiol
Artificial stimulation of the immune system to treat cancer
intrinsic regulators include molecules with ubiquitin ligase activity, including CBLB. More recently, CISH, a molecule with ubiquitin ligase activity, was found
Cancer_immunotherapy
and psychosis, but that "more work is needed to address the possibility of gene-environment correlation." In 2016 a meta-analysis was published on associations
Long-term_effects_of_cannabis
Group of stereoisomers
suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression". PeerJ. 1: e214. doi:10.7717/peerj.214. PMC 3840466. PMID 24282673
Cannabidivarin
Post-translational modification
catalyzing non-cullin protein neddylation, as has recently been the case for CBLb-mediated neddylation of PARP-1. To date, notable non-cullin neddylation substrates
Neddylation
Chemical compound
It can increase the TRPV1-mediated release of substance P and calcitonin gene-related peptide (CGRP) in rat dorsal spinal cord slices. Furthermore, NADA
N-Arachidonoyl_dopamine
Endogenous neuropeptide found in mammalian brain
CBCA CBCA-A CBCB CBCBA CBCP CBCPA CBCV CBCVA CBCQ Cannabicyclols CBL CBLA CBLB CBLP CBLPA CBLV CBLVA Cannabidiols CBD CBDA CBD-C1 CBD-C5 CBDB CBDBA CBDD
RVD-Hpα
Chemical compound
Intolerance, Hepatic Steatosis, and Novel Cannabinoid Receptor 1 Responsive Genes". PLOS ONE. 6 (11) e26415. Bibcode:2011PLoSO...626415R. doi:10.1371/journal
IDFP
travel, tourism, insurance
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