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CDC34

• CDC34

Protein-coding gene in humans

CDC34 is a gene that in humans encodes the protein Ubiquitin-conjugating enzyme E2 R1. This protein is a member of the ubiquitin-conjugating enzyme family

CDC34



CDC34

• Raymond J. Deshaies

American biochemist and cell biologist

Deshaies discovered a biochemical function for the ubiquitin-conjugated enzyme CDC34, which he showed mediates conjugation of ubiquitin onto G1 cyclin proteins

Raymond J. Deshaies

Raymond_J._Deshaies

• Protein folding

Change of a linear protein chain to a 3D structure

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Protein folding



Protein_folding

• Chaperone (protein)

Proteins assisting in protein folding

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Chaperone (protein)



Chaperone_(protein)

• Signal peptide

Short peptide present at N-terminal of newly synthesized proteins

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Signal peptide

Signal_peptide

• Post-translational modification

Chemical changes in proteins following their translation from mRNA

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Post-translational modification



Post-translational_modification

• CUL1

Protein-coding gene in humans

ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway". EMBO

CUL1



CUL1

• S-phase kinase-associated protein 1

Protein-coding gene in the species Homo sapiens

ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway". EMBO

S-phase kinase-associated protein 1



S-phase_kinase-associated_protein_1

• Let-7 microRNA family

RNA family

that are responsive to alteration of let-7 levels, including cyclin A2, CDC34, Aurora A and B kinases (STK6 and STK12), E2F5, and CDK8, among others.

Let-7 microRNA family

Let-7_microRNA_family

• SKP2

Protein-coding gene in the species Homo sapiens

ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway". The

SKP2



SKP2

• ATF5

Protein-coding gene in the species Homo sapiens

transcription factor 5". Pati D, Meistrich ML, Plon SE (July 1999). "Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced

ATF5



ATF5

• Heat shock protein

Family of proteins

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Heat shock protein

Heat_shock_protein

• NEDD8

Protein found in the human body

surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34". The Journal of Biological Chemistry. 277 (1): 516–27. doi:10.1074/jbc

NEDD8



NEDD8

• Heat shock protein 47

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Heat shock protein 47



Heat_shock_protein_47

• Ubiquitin ligase

Protein

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Ubiquitin ligase



Ubiquitin_ligase

• SCF complex

Type of protein

Temperature-sensitive cell division cycle (Cdc) mutants—such as Cdc4, Cdc34, and Cdc53—arrested in G1 with unreplicated DNA and multiple elongated buds

SCF complex



SCF_complex

• Survival of motor neuron

Protein in animal cells

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Survival of motor neuron



Survival_of_motor_neuron

• UFM1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UFM1



UFM1

• Protein targeting

Biological mechanism for routing proteins

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Protein targeting

Protein_targeting

• UBE2V2

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2V2



UBE2V2

• Ubiquitin-conjugating enzyme

Protein family

UBE2L2, UBE2L4 are pseudogenes) UBE2M UBE2N UBE2O UBE2Q1, UBE2Q2 UBE2R1 (CDC34), UBE2R2 UBE2S UBE2T (putative) UBE2U (putative) UBE2V1, UBE2V2 UBE2W (putative)

Ubiquitin-conjugating enzyme

Ubiquitin-conjugating_enzyme

• SUMO protein

Family of proteins which attach to other proteins to modify them

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

SUMO protein



SUMO_protein

• Heat shock protein 90kDa alpha (cytosolic), member A1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Heat shock protein 90kDa alpha (cytosolic), member A1



Heat_shock_protein_90kDa_alpha_(cytosolic),_member_A1

• UBE2R2

Protein-coding gene in the species Homo sapiens

gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating

UBE2R2



UBE2R2

• Ubiquitin

Regulatory protein found in most eukaryotic tissues

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Ubiquitin



Ubiquitin

• DNAJC1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJC1



DNAJC1

• DNAJA3

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJA3



DNAJA3

• Succinylation

Addition of a succinyl group to a lysine group of a protein

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Succinylation

Succinylation

• Hsp70

Family of heat shock proteins

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Hsp70



Hsp70

• CAMP responsive element modulator

Protein found in humans

PMID 10086359. S2CID 4424908. Pati D, Meistrich ML, Plon SE (July 1999). "Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced

CAMP responsive element modulator



CAMP_responsive_element_modulator

• Lysine malonylation

Post-translational modification

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Lysine malonylation



Lysine_malonylation

• Hsp27

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Hsp27



Hsp27

• Cullin

Hydrophobic scaffold protein

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Cullin



Cullin

• Hsp90

Heat shock proteins with a molecular mass around 90kDa

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Hsp90



Hsp90

• Target peptide

Type of peptide chain

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Target peptide

Target_peptide

• CSNK2B

Protein-coding gene in humans

to interact with CD163, CSNK2A2, Casein kinase 2, alpha 1, FGF1, TRIB3, CDC34, Ribosomal protein L5, BTF3, BRCA1, RNF7, P70-S6 Kinase 1 and APC. ENSG00000204435

CSNK2B



CSNK2B

• Cyclin-dependent kinase 9

Protein-coding gene in the species Homo sapiens

natural origin. CDK9 has been shown to interact with: Androgen receptor, CDC34 and CCNK, CCNT1, CCNT2, MYBL2, RELA, RB1, SKP1A. SUPT5H, and RNAP II. GRCh38:

Cyclin-dependent kinase 9



Cyclin-dependent_kinase_9

• Cell division control protein 4

proteins that differ only at their N-termini. Cdc4 protein interacts with Cdc34, an ubiquitin-conjugating enzyme, and Cdc53 in vivo. (There is a Cdc4p/Cdc53p-binding

Cell division control protein 4



Cell_division_control_protein_4

• FBXW11

Protein-coding gene in the species Homo sapiens

(gene) has been shown to interact with: FBXW11 DLG1 IκBα NFKB2 RELA SKP1A CDC34 CUL1 β-catenin WEE1 EMI1 Cdc25A Claspin REST PDCD4 DEPTOR βTrCP behaves

FBXW11



FBXW11

• List of human protein-coding genes 2

P30307 2578 CDC26 HGNC:17839; Q8NHZ8 2579 CDC27 HGNC:1728; P30260 2580 CDC34 HGNC:1734; P49427 2581 CDC37 HGNC:1735; Q16543 2582 CDC37L1 HGNC:17179;

List of human protein-coding genes 2

List_of_human_protein-coding_genes_2

• Ubiquitin-protein ligase E3B

Protein-coding gene in Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Ubiquitin-protein ligase E3B



Ubiquitin-protein_ligase_E3B

• RBX1

Protein-coding gene in the species Homo sapiens

surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34". The Journal of Biological Chemistry. 277 (1): 516–27. doi:10.1074/jbc

RBX1



RBX1

• UBE2E1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2E1



UBE2E1

• BTRC (gene)

Protein-coding gene in the species Homo sapiens

BTRC (gene) has been shown to interact with: β-catenin, BimEL1 Cdc25A, CDC34, Claspin, CUL1, DEPTOR, DLG1, EMI1, FBXW11, IκBα, NFKB2, PDCD4, RELA, REST

BTRC (gene)



BTRC_(gene)

• Chaperonin

Family of heat shock proteins

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Chaperonin



Chaperonin

• ISG15

Protein found in humans

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

ISG15



ISG15

• ATG12

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

ATG12



ATG12

• Ubiquitin-activating enzyme

Class of enzymes

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Ubiquitin-activating enzyme



Ubiquitin-activating_enzyme

• ATG8

Protein in budding yeast

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

ATG8



ATG8

• SMN1

Protein-coding gene in humans

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

SMN1



SMN1

• CBL (gene)

Mammalian gene

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

CBL (gene)



CBL_(gene)

• Deubiquitinating enzyme

Protein family

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Deubiquitinating enzyme



Deubiquitinating_enzyme

• Neddylation

Post-translational modifications involving the protein NEDD8

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Neddylation



Neddylation

• Binding immunoglobulin protein

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Binding immunoglobulin protein



Binding_immunoglobulin_protein

• Prokaryotic ubiquitin-like protein

Protein family

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Prokaryotic ubiquitin-like protein



Prokaryotic_ubiquitin-like_protein

• HSPA1A

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSPA1A



HSPA1A

• Hsp33

InterPro Family

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Hsp33

Hsp33

• SMN2

Protein-coding gene in humans

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

SMN2



SMN2

• Mdm2

Protein-coding gene in humans

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Mdm2



Mdm2

• Clusterin

Protein found in humans

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Clusterin



Clusterin

• HSPA8

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSPA8



HSPA8

• UBE2I

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2I



UBE2I

• HSP90B1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSP90B1



HSP90B1

• UBA1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBA1



UBA1

• HSPA4

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSPA4



HSPA4

• Ataxin 3

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Ataxin 3



Ataxin_3

• UBE2C

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2C



UBE2C

• Ubiquitin-like protein

Family of small proteins

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Ubiquitin-like protein



Ubiquitin-like_protein

• DNAJB4

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJB4



DNAJB4

• GroEL

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

GroEL



GroEL

• FANCL

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

FANCL



FANCL

• DNAJA2

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJA2



DNAJA2

• HSP90AB1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSP90AB1



HSP90AB1

• DNAJB9

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJB9



DNAJB9

• GroES

Protein

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

GroES



GroES

• Von Hippel–Lindau tumor suppressor

Mammalian protein found in humans

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Von Hippel–Lindau tumor suppressor



Von_Hippel–Lindau_tumor_suppressor

• URM1

Protein family

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

URM1



URM1

• UBE2N

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2N



UBE2N

• DNAJA1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJA1



DNAJA1

• USP6

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

USP6



USP6

• Auxilin

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

Auxilin



Auxilin

• UBE2V1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2V1



UBE2V1

• UBE2A

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2A



UBE2A

• UBE2D2

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2D2



UBE2D2

• DNAJC3

Human protein and coding gene

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJC3



DNAJC3

• DNAJB1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJB1



DNAJB1

• DNAJB2

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJB2



DNAJB2

• HSPA7

Pseudogene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSPA7

HSPA7

• BIRC6

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

BIRC6



BIRC6

• UBE2G1

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2G1



UBE2G1

• HSPA1B

Human gene

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSPA1B



HSPA1B

• UBE2L3

Protein-coding gene in humans

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2L3



UBE2L3

• HSPA12A

Human gene

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSPA12A

HSPA12A

• UBR1

Mammalian protein found in Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBR1



UBR1

• DNAJC5

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJC5



DNAJC5

• DNAJB6

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJB6



DNAJB6

• HSPA14

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSPA14



HSPA14

• UBE2L6

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

UBE2L6



UBE2L6

• DNAJC14

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

DNAJC14



DNAJC14

• HSPA9

Protein-coding gene in the species Homo sapiens

B C D1 D2 D3 E1 E2 E3 G1 G2 H I J1 J2 K L1 L2 L3 L4 L6 M N O Q1 Q2 R1 (CDC34) R2 S V1 V2 Z E3 Ubiquitin ligase VHL Cullin CBL MDM2 FANCL UBR1 Deubiquitinating

HSPA9



HSPA9

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Online names & meanings

• Taba

Girl/Female

Arabic, Muslim

Taba

Clean

• Playford

Surname or Lastname

English (mainly Norfolk)

Playford

English (mainly Norfolk) : habitational name from a place in Suffolk, so called from Old English plæga, plega ‘sport’, ‘play’ + ford ‘ford’.

• Aldan

Boy/Male

English

Aldan

From the old manor.

• Karn

Boy/Male

Hindu

Karn

The ear

• Walcott

Boy/Male

Anglo, British, English

Walcott

From the Cottage by the Wall; Lives in the Welshman's Cottage

• Yasheena

Girl/Female

Arabic, Muslim

Yasheena

Joy

• Terrys

Boy/Male

American, Australian, British, English

Terrys

Son of Terrell

• Naarai

Girl/Female

Biblical

Naarai

Young person.

• Yudhajit

Boy/Male

Hindu

Yudhajit

Victor in war, A hero, Soldier, Of a king of the kekayas and maternal uncle of Bharata

• Timoteo

Boy/Male

Spanish

Timoteo

one who honors God.

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CDC34

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