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Chemical compound
Celastrol (tripterine) is a bioactive chemical compound isolated from the roots of Tripterygium wilfordii (Thunder duke vine) and Tripterygium regelii
Celastrol
Chemical compound
noted antimicrobial properties. It is also a biological precursor of celastrol. Friedelane is found in the wood of Calophyllum tomentosum, as well as
Friedelane
Species of flowering plant
wilfordii extract is a useful remedy for postmenopausal rheumatoid arthritis. Celastrol, a pentacyclic triterpenoid, and triptolide, a diterpene triepoxide, are
Tripterygium_wilfordii
Chemical compound
corkboard manufacturing. The compound is also a biological precursor of celastrol. It is considered a friedelane-type compound, appearing structurally similar
Friedelin
Chemical compound
identified from natural sources. Some are bioactive with promise as medicines. Celastrol is a triterpenoid quinone methide isolated from Tripterygium wilfordii
Quinone_methide
Medical condition
BCR-Abl's activity by blocking the active kinase domain (Fava et al., 2011). Celastrol is a compound extracted from Tripterygium wilfordii that has anti-cancer
Acute myeloblastic leukemia with maturation
Acute_myeloblastic_leukemia_with_maturation
02.012. PMID 24680370. Yang H, Chen D, Cui QC, Yuan X, Dou QP (2006). "Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent
Bark_isolate
Mammalian protein found in Homo sapiens
ligands that directly bind NR4A1, including cytosporone B, dexamethasone, celastrol, and certain polyunsaturated fatty acids. These NR4A1 ligands bind at
Nuclear_receptor_4A1
Chemical compound
terpenoids, alkaloids, lignans, and diterpenes. Among these, triptolide and celastrol have been extensively studied for their potent biological activities.
Demethylzeylasteral
inhibition of Th17/Th22 pathway in 2D and 3D human models of psoriasis by Celastrol enriched plant cell culture extract". Journal of the European Academy
Th22_cell
Protein found in humans
Meng Y, et al. (11 July 2013). "ER stress-mediated apoptosis induced by celastrol in cancer cells and important role of glycogen synthase kinase-3β in the
PSMB1
(2021). "The genome of Tripterygium wilfordii and characterization of the celastrol biosynthesis pathway". Gigabyte. 2021: 1–30. doi:10.46471/gigabyte.14
List of sequenced plant genomes
List_of_sequenced_plant_genomes
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