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Medication used to treat malaria
Chloroquine is an antiparasitic medication that treats malaria. It works by increasing the levels of heme in the blood, a substance toxic to the malarial
Chloroquine
Medical condition
Chloroquine retinopathy is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes
Chloroquine_retinopathy
Antimalarial medication
prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria
Hydroxychloroquine
Early experimental treatment efforts during the start of COVID-19 pandemic
Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. Chloroquine, along with hydroxychloroquine
Chloroquine and hydroxychloroquine during the COVID-19 pandemic
Chloroquine_and_hydroxychloroquine_during_the_COVID-19_pandemic
Medication used to treat malaria and babesiosis
treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal
Quinine
Agents used in the treatment of malaria
affect some individuals taking standard doses (e.g., retinopathy with chloroquine, acute haemolytic anaemia with tafenoquine). Antimalarial drugs may be
Antimalarial_medication
Mosquito-borne disease
evolved resistance to several antimalarial medications; for example, chloroquine-resistant P. falciparum has spread to most malaria-prone areas and resistance
Malaria
Medication
Atabrine or Atebrin, is a medication with several uses. It is related to chloroquine and mefloquine. Although available from compounding pharmacies, as of
Mepacrine
Human disease caused by amoeba protists
with either metronidazole, tinidazole, nitazoxanide, dehydroemetine or chloroquine, and luminal infection is treated with diloxanide furoate or iodoquinoline
Amoebiasis
Species of single-celled organism
geographically contiguous Papua New Guinea, where chloroquine resistance is common (up to 20% resistance). Chloroquine resistance is an increasing problem in other
Plasmodium_vivax
Accelerated multinational clinical trial program to identify therapies against COVID-19
combined with interferon-beta, and hydroxychloroquine or chloroquine. Hydroxychloroquine or chloroquine investigation was discontinued in June 2020 due to concluding
Solidarity_trial
Contagious disease caused by SARS-CoV-2
promising drugs: An experimental drug called remdesivir Anti-malarial drugs chloroquine and hydroxychloroquine Two anti-HIV drugs, lopinavir/ritonavir and interferon-beta
COVID-19
Chemical compound
combination medication used to treat and prevent malaria, including chloroquine-resistant malaria. It contains atovaquone and proguanil. It is not recommended
Atovaquone/proguanil
Benzodiazepine sedative
to sarin, VX, or soman (or other organophosphate poisons), lindane, chloroquine, physostigmine, or pyrethroids. Diazepam is sometimes used intermittently
Diazepam
Indian multinational pharmaceutical company
largest global suppliers of the antimalarials hydroxychloroquine and chloroquine, as well as of APIs such as atenolol, chlorthalidone, losartan and metoprolol
Ipca_Laboratories
Formulary by the World Health Organization
tetraphosphate) Artesunate + sulfadoxine/pyrimethamine (Co-packaged) Chloroquine Dihydroartemisinin/piperaquine phosphate (dihydroartemisinin + piperaquine
WHO Model List of Essential Medicines
WHO_Model_List_of_Essential_Medicines
prescribed in malaria endemic areas, and new therapeutic drugs, including chloroquine and artemisinins, were used to resist the scourge. Today, artemisinin
History_of_malaria
episodes over the course of 6 seasons. Dwilson, Stephanie Dube (May 6, 2020). "'Dead Zone' Plague Episode Predicts Coronavirus & Chloroquine". Heavy.
List of The Dead Zone episodes
List_of_The_Dead_Zone_episodes
Heme biocrystallization is inhibited by quinoline antimalarials such as chloroquine. Targeting heme biocrystallization remains one of the most promising
Biocrystallization
President of the United States from 1993 to 2001
Sudan's medicine, and the destruction of the plant led to a shortage of chloroquine, a drug which is used to treat malaria. U.S. officials later acknowledged
Bill_Clinton
Chemical compound
China as a replacement for the structurally similar antimalarial drug chloroquine. Due to widespread parasite resistance to piperaquine, the drug fell
Piperaquine
Medical prevention of malaria
also be used for therapy in some cases. In areas where chloroquine remains effective: chloroquine 300 mg once weekly, and proguanil 200 mg once daily (started
Malaria_prophylaxis
Academic journal
Corporation, which concluded that the malaria drugs hydroxychloroquine and chloroquine did not improve the condition of COVID-19 patients, and may have harmed
The_Lancet
British scientist (1938–2021)
London School of Hygiene and Tropical Medicine LSHTM, where he worked on chloroquine resistance in malaria. In the late 1960s he was a Research Fellow with
David_Warhurst
Pharmaceutical drug
be forthcoming soon. Use of primaquine in combination with quinine or chloroquine each of which is very effective at clearing P. vivax from blood, improves
Primaquine
Lebanese-American media personality (born 1993)
mentioned that a study published in The Lancet on the effectiveness of chloroquine as a COVID-19 treatment was carried out by a company whose sales manager
Mia_Khalifa
Chemical compound
treating erythrocytic plasmodial infections. Examples include amodiaquine, chloroquine, and hydroxychloroquine. Other uses for the derivatives are: anti-asthmatic
4-Aminoquinoline
Chemical compound
often used together with chloroquine or atovaquone. When used with chloroquine the combination will treat mild chloroquine resistant malaria. It is taken
Proguanil
American cult leader and mass murderer (1931–1978)
Flavor Aid, poisoned with diphenhydramine, promethazine, chlorpromazine, chloroquine, chloral hydrate, diazepam, and cyanide. As members of Ryan's delegation
Jim_Jones
Conservative political advocacy organization
effective for preventing infection. Several countries initially used chloroquine or hydroxychloroquine for treatment of persons hospitalized with COVID-19
Association of American Physicians and Surgeons
Association_of_American_Physicians_and_Surgeons
Aspect of 2020 viral outbreak
developed, and promoted unapproved treatments such as hydroxychloroquine and chloroquine. In such instances, scientists, including Anthony Fauci, Michael Osterholm
Communication of the Trump administration during the COVID-19 pandemic
Communication_of_the_Trump_administration_during_the_COVID-19_pandemic
Chemical compound
a synthetic compound related to chloroquine which acts as an antimalarial, and shows good activity against chloroquine-resistant strains. It contains an
Ferroquine
Medical condition
corticosteroids are not effective as treatment for LET, but many will respond to chloroquine. LET resolves with normal skin, no residual scarring, no hyperpigmentation
Tumid_lupus_erythematosus
Cocktail of drugs ineffective in treating COVID-19
COVID-19. This approach includes advocating for the use of drugs such as chloroquine, hydroxychloroquine, ivermectin, azithromycin, bromhexine, nitazoxanide
COVID_kit
Chemical entity that reversibly binds ions
antioxidant and neuroprotective properties of different ionophores. Chloroquine is an antimalarial and antiamebic drug. It is also used in the management
Ionophore
Dictator of Cambodia from 1975 to 1979
Pot died after ingesting a lethal dose of a combination of Valium and chloroquine". His body was preserved with ice after an improvised embalming with
Pol_Pot
Chemical compound
treatment with Bafillomycin of 1 nM decreased chloroquine induced apoptosis without affecting chloroquine inhibition of autophagy. The exact mechanism
Bafilomycin
Chemical compound used as an intermediate to antimalarial drugs
intermediate to aminoquinoline antimalarial drugs including amodiaquine, chloroquine and hydroxychloroquine. 4,7-Dichloroquinoline was first reported in a
4,7-Dichloroquinoline
Parasitic disease that results in diarrhea
metronidazole. Other drugs, such as nitazoxanide, albendazole, quinacrine, chloroquine, paromomycin, and other drug combinations are also used in clinics. Refractory
Giardiasis
Antibiotic
the test result is negative and clindamycin can be used. Given with chloroquine or quinine, clindamycin is effective and well tolerated in treating Plasmodium
Clindamycin
Initial drug used as a reference
Nifedipine is the prototype dihydropyridine calcium channel blocker Chloroquine is the prototypical antimalarial agent Acyclovir is the prototype antiviral
Prototype_drug
German chemist (1902–1955)
German chemist (1902–1955). While working for Bayer AG, he discovered chloroquine, the active ingredient in the malaria drug Resochin. He also first synthesized
Hans_Andersag
American TV host and government official (born 1960)
Michael (April 1, 2020). "Column: The rotten science behind Trump's chloroquine obsession". Los Angeles Times. Archived from the original on April 27
Mehmet_Oz
Type of autoimmune arthritis
40–50 days for Hydroxychloroquine as compared to up to 60 days for Chloroquine. More recent studies suggest a shorter half-life of about 5 days. A long
Rheumatoid_arthritis
False or misleading virus information
medicine "helps fight coronavirus [disease 2019]". There were claims that chloroquine was used to cure more than 12,000 COVID-19 patients in Nigeria. In March
COVID-19_misinformation
Broad-spectrum herbicide
L-Cycloserine Propargylglycine GDHTooltip Glutamate dehydrogenase AAOA Bithionol Chloroquine EGCG GTP GW5074 Hexachlorophene Hydroxylamine Palmitoyl-CoA Pyridoxal
Glufosinate
Solid part of maxilla
defect. Palatal abscesses may also occur. Long-term use of the drug chloroquine diphosphatase, used in malaria prophylaxis, rheumatoid arthritis and
Hard_palate
Amino acid
L-Cycloserine Propargylglycine GDHTooltip Glutamate dehydrogenase AAOA Bithionol Chloroquine EGCG GTP GW5074 Hexachlorophene Hydroxylamine Palmitoyl-CoA Pyridoxal
Theanine
Indian profession
Oral Rehydration Salts (ORS) Therapy, Iron Folic Acid (IFA) Tablets, Chloroquine, Disposable Delivery Kits (DDK), Oral Pills & Condoms. Their responsibilities
Accredited Social Health Activist
Accredited_Social_Health_Activist
Species of flowering plant
activities, among others. Bankole et al 2016 find M. longifolium does control chloroquine resistant strains of Plasmodium berghei ANKA in mouse to some degree
Monoon_longifolium
Drug repurposing research related to COVID-19
that have been investigated include chloroquine, hydroxychloroquine, mefloquine, ivermectin, and atovaquone. Chloroquine and hydroxychloroquine are anti-malarial
COVID-19 drug repurposing research
COVID-19_drug_repurposing_research
Muscular disease in which the muscle fibers do not function correctly
Toxic myopathies: alcohol, corticosteroids, narcotics, colchicines, chloroquine Critical illness myopathy Metabolic myopathies Paraneoplastic myopathy
Myopathy
Crystalline waste product of parasitic blood digestion
Achilles' heel). Several currently used antimalarial drugs, such as chloroquine and mefloquine, are thought to kill malaria parasites by inhibiting haemozoin
Hemozoin
Medical condition
is inhibited. Low doses of antimalarials can be used. Orally ingested chloroquine is completely absorbed in the gut and is preferentially concentrated
Porphyria_cutanea_tarda
Pharmaceutical drug
treatment for chloroquine-sensitive or resistant Plasmodium falciparum malaria, and is deemed a reasonable alternative for uncomplicated chloroquine-resistant
Mefloquine
Antiviral drug
Using chloroquine or hydroxychloroquine with remdesivir may reduce the antiviral activity of remdesivir. Coadministration of remdesivir and chloroquine phosphate
Remdesivir
Abnormal patches of white hair
prostaglandin analogs (used in glaucoma treatment) and systemic drugs like chloroquine and acitretin. Several genetic and acquired disorders can mimic poliosis
Poliosis
American journalist (born 1976)
effectiveness against coronavirus of certain older drug therapies such as chloroquine that have been effective on other conditions. Alexander asked: "Is it
Peter_Alexander_(journalist)
Theoretical drug measure in pharmacology
{\displaystyle f_{u_{T}}} : fraction unbound in tissue For example, chloroquine has much greater affinity for body fat than blood, resulting in a V D
Volume_of_distribution
Hemoglobin with ferric iron unable to carry oxygen
anesthetic agents, especially prilocaine and benzocaine. Amyl nitrite, chloroquine, dapsone, nitrates, nitrites, nitroglycerin, nitroprusside, phenacetin
Methemoglobin
doses of hydroxychloroquine, 10,000 of Zithromax, and 750,000 doses of chloroquine to the state. North Carolina: Mecklenburg County announced that they
Timeline of the COVID-19 pandemic in the United States (2020)
Timeline_of_the_COVID-19_pandemic_in_the_United_States_(2020)
Abnormal formation of clumps of inflammatory cells (granulomata)
such as prednisone are indicated. Medications such as methotrexate, chloroquine, or azathioprine may occasionally be used in an effort to decrease the
Sarcoidosis
French biology researcher (born 1952)
sound", and criticised its members for "not having a clue". He defended chloroquine as a benchmark drug for lung diseases, saying that it had suddenly been
Didier_Raoult
Category 5 Atlantic hurricane in 1980
anti-malaria office to request the drug chloroquine from the US government. A total of 4.65 million chloroquine tablets were sent to Haiti in August and
Hurricane_Allen
Medical condition
a vacuolar myopathy without significant cell death or inflammation. Chloroquine/hydroxychloroquine prescriptions can cause a development of a progressively
Acquired non-inflammatory myopathy
Acquired_non-inflammatory_myopathy
France, hydroxychloroquine (the less toxic version of the malaria drug chloroquine) was also tested: in Lazio, its use was reported by the second week of
COVID-19_pandemic_in_Italy
Chronic muscular inflammation, primarily of the endomysium
with corticosteroids, amiodarone, cyclosporine, statins, colchicine, chloroquine or hydroxychloroquine, and chronic alcohol exposure just to name a few
Polymyositis
Species of single-celled organism
infect humans. Treatment is similar to other types of malaria, with chloroquine or artemisinin combination therapy typically recommended. P. knowlesi
Plasmodium_knowlesi
they had the potential to treat COVID-19 patients. Among those were chloroquine and hydroxychloroquine, which have been successfully used to treat malaria
United States responses to the COVID-19 pandemic
United_States_responses_to_the_COVID-19_pandemic
Form of scleroderma involving isolated patches of hardened skin
systemic corticosteroids. Antimalarials such as hydroxychloroquine or chloroquine have been used. Other immunomodulators such as methotrexate, topical
Morphea
Chemical compound
was a potential alternative to the preexisting combination therapy of chloroquine and sulfadoxine/pyrimethamine, as malaria was showing drug resistance
Chlorproguanil
Ukrainian-American physician (1973–2022)
cancer for several years. He is survived by his wife and eight children. Chloroquine and hydroxychloroquine during the COVID-19 pandemic "Dr. Vladimir Zelenko
Vladimir_Zelenko
Brazilian physician and author
During the COVID-19 pandemic, Ribeiro publicly endorsed the use of chloroquine and ozone therapy as treatments for coronavirus disease 2019, despite
Lair_Ribeiro
Chinese researcher at the Wuhan Institute of Virology
team published a paper in Cell Research showing that remdesivir and chloroquine inhibited the virus in vitro, and applied for a patent for the drug in
Shi_Zhengli
Chinese pharmaceutical chemist (born 1930)
where a majority came down with a form of malaria which is resistant to chloroquine. Because malaria was also a major cause of death in China's southern
Tu_Youyou
Comune in Trentino-Alto Adige/Südtirol, Italy
he died in Lana Hans Andersag (1902–1955) a scientist who discovered chloroquine Karl Zuegg (1914 – 2005) an Italian entrepreneur, MD of the Lana fruit
Lana,_South_Tyrol
Chemical compound
L-Cycloserine Propargylglycine GDHTooltip Glutamate dehydrogenase AAOA Bithionol Chloroquine EGCG GTP GW5074 Hexachlorophene Hydroxylamine Palmitoyl-CoA Pyridoxal
Methionine_sulfoximine
Local anesthetic
component of the veterinary drug Tributame along with embutramide and chloroquine used to carry out euthanasia on horses and dogs. Lidocaine, the first
Lidocaine
Sudanese complex bombed by the US in 1998
medicines, and its destruction has left the country with no supplies of chloroquine, the standard treatment for malaria". He also noted that the British
Al-Shifa pharmaceutical factory
Al-Shifa_pharmaceutical_factory
Chemical compound
acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It
Artemotil
Combination drug
caused by Plasmodium falciparum than that caused by P. vivax, for which chloroquine is considered more effective, though in the absence of a species-specific
Sulfadoxine/pyrimethamine
Phylum of protozoans
with either metronidazole, tinidazole, nitazoxanide, dehydroemetine or chloroquine, while luminal infection is treated with diloxanide furoate or iodoquinoline
Amoebozoa
Bilateral relations between India and Israel
consignment included ingredients for the drugs hydroxychloroquine and chloroquine. On this occasion, Sanjeev Singla, India's then ambassador to Israel
India–Israel_relations
Anti-parasite medication
phenytoin are reported to reduce the bioavailability of praziquantel. Chloroquine also reduces its bioavailability. Experimental evidence indicates praziquantel
Praziquantel
Indonesian emergency medicine physician
them to others. Corona publicly stated his concern about people using chloroquine for self-medication, touted by both Indonesian President Joko Widodo
Corona_Rintawan
Sedating antihistamine
Martin RE, Barrow RA (May 2014). "Chlorpheniramine Analogues Reverse Chloroquine Resistance in Plasmodium falciparum by Inhibiting PfCRT". ACS Medicinal
Promethazine
Medical condition
and hypotension (low blood pressure).[citation needed] Quinine, like chloroquine, inactivates enzymes in the lysosomes of cells and has an anti-inflammatory
Cinchonism
American politician (born 1964)
G. (December 2021). "Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized
Doug_Mastriano
Mammalian protein
L-Cycloserine Propargylglycine GDHTooltip Glutamate dehydrogenase AAOA Bithionol Chloroquine EGCG GTP GW5074 Hexachlorophene Hydroxylamine Palmitoyl-CoA Pyridoxal
Alanine_transaminase
Administering drugs to a whole population in order to prevent disease
needed] During a pilot programme in Uganda in 1959 mass administration of chloroquine / pyrimethamine was combined with spraying of residual insecticides (DDT)
Mass_drug_administration
Chemical compound
in Cameroon, pyronaridine had a 100% cure rate, compared with 60% for chloroquine. It is one of the components of the artemisinin combination therapy
Pyronaridine
Neuropsychiatric quinism is a chronic encephalopathy due to intoxication by chloroquine, quinacrine, mefloquine, and tafenoquine. It is associated with brain
Quinism
Typical antipsychotic medication
example, Miki et al. 1992 trialed daily doses of chlorpromazine, reversing chloroquine resistance in Plasmodium chabaudi isolates in mice. Weeks et al., 2018
Chlorpromazine
Topics referred to by the same term
Rodenstock also known as Tiefenbildner Imagon (drug), a trade name for the Chloroquine drug Imago (disambiguation) Imacon This disambiguation page lists articles
Imagon
Hospital in Zürich, Switzerland
Medical School on the use of the antimalarial drugs hydroxychloroquine and chloroquine for COVID-19 treatment. The research, published in The Lancet, found
University_Hospital_of_Zurich
Gradual retinal degeneration leading to progressive sight loss
autoimmune paraneoplastic retinopathy, drug toxicity (phenothiazines and chloroquine, less commonly with thioridazine and hydroxychloroquine), diffuse unilateral
Retinitis_pigmentosa
Chemical compound
compound related to chloroquine. The side effects of amodiaquine are generally minor to moderate and are similar to those of chloroquine. Rarely liver problems
Amodiaquine
Amino acid
L-Cycloserine Propargylglycine GDHTooltip Glutamate dehydrogenase AAOA Bithionol Chloroquine EGCG GTP GW5074 Hexachlorophene Hydroxylamine Palmitoyl-CoA Pyridoxal
Aspartic_acid
Sulfa drug
infections by Haemophilus influenzae. It is also used as adjunct therapy for chloroquine-resistant malaria and several forms of bacterial meningitis. It is taken
Sulfadiazine
Medical condition
haloperidol, chlorpromazine, fluphenazine, olanzapine), carbamazepine, chloroquine, cisplatin, diazoxide, levodopa, lithium, metoclopramide, lurasidone
Oculogyric_crisis
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