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Use of more than one medication or modality together to treat a single condition
Combination therapy or polytherapy is therapy that uses more than one medication or modality. Typically, the term refers to using multiple therapies to
Combination_therapy
Agents used in the treatment of malaria
therapies. Though antimalarial drugs have repeatedly been observed to elicit resistance in the malaria parasite—including for combination therapies featuring
Antimalarial_medication
serially or in combination leading to the development of multi-drug resistant mutations. In contrast, antiretroviral combination therapy defends against
Management_of_HIV/AIDS
Attempted medical remediation of a health problem
word therapy. Therapy as a treatment for physical or mental condition is based on knowledge usually from one of three separate fields (or a combination of
Therapy
Concept in pharmacology and biochemistry
a majority of combination therapies, although synergistic effect is more common. If the combination of two drugs in combination therapy has an effect
Additive_effect
Medication
et al. (February 2008). "The effects of dutasteride, tamsulosin and combination therapy on lower urinary tract symptoms in men with benign prostatic hyperplasia
Tamsulosin
Antimicrobial substance active against bacteria
infections may be treated with a combination therapy of fusidic acid and rifampicin. Antibiotics used in combination may also be antagonistic and the
Antibiotic
Psychiatric medication used to treat mood disorders
effective for acute and/or maintenance therapy. Thus, most patients are placed on combination therapy. Combination therapy (e.g., an atypical antipsychotic
Mood_stabilizer
Medication against high blood pressure
and without heart failure. It can be used as either monotherapy or combination therapy for the management of hypertension or coronary artery disease. Amlodipine
Amlodipine
Pharmaceutical compound
treated with a combination of three cancer-inhibiting agents, daraxonrasib, afatinib, and SD36. Mice treated with this combination therapy had far more
Daraxonrasib
Class of anticancer drugs
blockade therapy is not effective for all patients, as some may exhibit resistance. To overcome resistance, a strategy involving the combination of PD-1/PD-L1
PD-1_and_PD-L1_inhibitors
Type of autoimmune arthritis
anti-rheumatic drugs. The levels of miRNA before and after anti-TNFa/DMRADs combination therapy are potential novel biomarkers for predicting and monitoring the
Rheumatoid_arthritis
Drug with two or more active ingredients
(intramuscular administration or intravenous therapy), or a suppository (rectal). A legitimate combination drug that exceeds rigorous laboratory quality
Combination_drug
High blood pressure medication
the effects of the established therapy of the combination of atenolol and bendroflumethiazide to the new drug combination of amlodipine and perindopril
Perindopril
Mental disorder associated with trauma
people with PTSD are counselling (psychotherapy) and medication. Most combination therapy (psychotherapy and pharmacotherapy) does not seem to be more effective
Post-traumatic stress disorder
Post-traumatic_stress_disorder
Medical condition
"The effectiveness of combination therapies for androgenetic alopecia: A systematic review and meta-analysis". Dermatologic Therapy. 33 (4) e13741. Hindawi
Pattern_hair_loss
Spectrum of mood disorders
be combined with benzodiazepines to treat catatonic depression. Combination therapy can help relieve symptoms and enhance overall function. When medication
Catatonic_depression
Skin condition characterized by pimples
review of cosmetic therapies". Cutis (Review). 95 (5): 276–81. PMID 26057505. Kroepfl L, Emer JJ (November 2016). "Combination Therapy for Acne Scarring:
Acne
Autoimmune disease
however studies of combination therapy are limited, and five meta-analyses/reviews "suggested no clear advantage of the combination therapy". However, subgroup
Hashimoto's_thyroiditis
Type of chewing gum that delivers nicotine to the body
nicotine polacrilex. It is a type of nicotine replacement therapy (NRT) used alone or in combination with other pharmacotherapy for smoking cessation and for
Nicotine_gum
Combination drug
Ghorashian S, Arnold U, et al. (July 2009). "Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis:
Nifurtimox/eflornithine
Alternative cancer treatment
The Issels treatment, or Issels combination therapy, is an alternative cancer treatment based on the ideas of Josef Issels. The treatment is considered
Issels_treatment
Medication investigated as a treatment for progeria
in people one year of age and older. It is under trial for its use as combination treatment for Hepatitis D Virus. The most common side effects included
Lonafarnib
Pharmaceutical drug
and Drug Administration (FDA), in September 2021, granted Breakthrough Therapy designation for disitamab vedotin for the second-line treatment of patients
Disitamab_vedotin
Group of drugs used against malaria
in Physiology or Medicine for her discovery. Artemisinin-based combination therapies (ACTs) have become standard treatment worldwide for P. falciparum
Artemisinin
Medication
combination with sulbactam to treat susceptible strains of bacteria in the genus Acinetobacter It is an analog of avibactam. The combination therapy
Durlobactam
minoxidil and ketoconazole are more effective than individual use. Combination therapy of LLLT or microneedling with finasteride or minoxidil demonstrated
Management_of_hair_loss
Abnormally low sperm count
problems coexist on the female side. The Low dose Estrogen Testosterone Combination Therapy may improve sperm count and motility in some men including severe
Oligospermia
Specific application of intentional sleep deprivation
Wake therapy (sometimes sleep deprivation therapy) is a specific application of intentional sleep deprivation. It encompasses many sleep-restricting paradigms
Wake_therapy
Tonsil cancer that has material basis in squamous cells
such as asbestos and perchloroethylene in certain occupations, radiation therapy and dietary factors. The early lesions are usually asymptomatic. The patients
Tonsil_carcinoma
Protein found in humans
anti-CTLA-4 therapy resulted in an increase in efficacy that was about four to five times as large as that of control treatments. This combination therapy incorporating
ICOS_(gene)
German biotechnology company
pipeline includes several late-stage programs in oncology testing combination therapy approaches to improve treatment outcomes. In the field of infectious
BioNTech
Chemical compound
molecules. In diabetic patients, the short-term effect of these drug therapies is to decrease current blood glucose levels; the long-term effect is a
Acarbose
Class of drugs
Nitin J.; Patel, Mahesh; Sangle, Ganesh V. (May 2020). "Glucagon-based therapy: Past, present and future". Peptides. 127 170296. doi:10.1016/j.peptides
Glucagon_receptor_agonist
climatotherapy cobalt therapy cold compression therapy combination therapy consolidation therapy contrast bath therapy counseling craniosacral therapy (mostly pseudoscientific)
List_of_therapies
Research into combination antibiotics is ongoing. Bassetti, Matteo; Righi, Elda (October 2015). "New antibiotics and antimicrobial combination therapy for the
Combination_antibiotic
Any chemical that inhibits the function of CDKs
administered in combination with letrozole increased the likelihood of progression free survival to 63% in the first 18 months of therapy versus 42% for
CDK_inhibitor
French physician and researcher (1942–2020)
retrovirus as the cause of AIDS, and his ground-breaking use of triple combination therapy for the effective control of HIV in the patient. A practicing physician
Jacques_Leibowitch
Class of drugs to lower cholesterol
lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin. Combination preparations of a statin and another agent, such as ezetimibe/simvastatin
Statin
Combination of antihypertensive drugs
excess water and salt in the body. Several organizations recommend combination therapy for hypertension in cases of failure of a single drug to achieve
ACE inhibitor and thiazide combination
ACE_inhibitor_and_thiazide_combination
Insufficient production of thyroid hormones
and T3 therapy carried a higher rate of side effects and no benefit over T4 alone. Similarly, American guidelines discourage combination therapy due to
Hypothyroidism
Skin condition
further darkening of the affected skin. In severe or recurrent cases, combination therapy of hydroquinone plus one or more additional topical agents is common
Postinflammatory hyperpigmentation
Postinflammatory_hyperpigmentation
Surgical using radiation
administered alone or in combination with other therapies. For brain metastases, these treatment options include whole brain radiation therapy (WBRT), surgery
Radiosurgery
Fixed dose combination HIV drug
antiretroviral therapy in several countries, including the European Union, the United Kingdom and the United States. The combination is indicated for
Bictegravir/emtricitabine/tenofovir alafenamide
Bictegravir/emtricitabine/tenofovir_alafenamide
Type of physical therapy
Inversion therapy, or simply inversion, is the process of seeking therapeutic benefits from hanging by the legs, ankles, or feet in an inverted angle
Inversion_therapy
Chemical compound
preferred to quinine for severe malaria. Often it is used as part of combination therapy, such as artesunate plus mefloquine. It is not used for the prevention
Artesunate
Chemical compound
designated the combination an orphan medicine. The FDA and the EMA granted the application for elexacaftor, tezacaftor, and ivacaftor combination therapy an orphan
Tezacaftor
Medication used to treat a viral infection
treatment ends. Once SVR is achieved, treatment is considered a success. Combination therapy of interferon and ribavirin has a SVR rate of approximately 65%.
Antiviral_drug
Combination cytotoxic phototherapy
Photodynamic/photothermal combination therapy involves the usage of a chemical compound or nanomaterial that, when irradiated at a certain wavelength
Combined photothermal and photodynamic therapy
Combined_photothermal_and_photodynamic_therapy
Central nervous system stimulant prodrug
romantic relationships). Long-term combination therapy for ADHD (i.e., treatment with both a stimulant and behavioral therapy) produces even larger effect sizes
Lisdexamfetamine
Anticonvulsant medication
opioids or other CNS depressants. A 2022 meta-analysis found that combination therapy with opioids and gabapentinoids could be associated with an increased
Pregabalin
Species of single-celled organism
similar to other types of malaria, with chloroquine or artemisinin combination therapy typically recommended. P. knowlesi malaria is an emerging disease
Plasmodium_knowlesi
Disease caused by parasites of the Leishmania type
infection. Recent research in leishmaniasis treatment explores combination therapies, nanotechnology-based drugs, and immunotherapy. For cutaneous disease
Leishmaniasis
lymphoblastic leukemia 1965 – MOPP regimen combination therapy cures advanced Hodgkin's lymphoma, with the combination of: nitrogen mustard, vincristine, procarbazine
Timeline of cancer treatment development
Timeline_of_cancer_treatment_development
Deuterated cystic fibrosis drug (ivacaftor analogue)
for vanzacaftor, tezacaftor, and deutivacaftor combination therapy orphan drug designation. The combination was approved for medical use in the United States
Vanzacaftor/tezacaftor/deutivacaftor
Vanzacaftor/tezacaftor/deutivacaftor
German physician (1907–1998)
concluded that there was no evidence that treatment with Issels Combination Therapy or any related treatments were effective against cancer. Issels wrote
Josef_Issels
Drug of the fibrate class, mainly used to reduce cholesterol levels
Calculi (Kidney Stones) When fenofibrate and a statin are given as combination therapy, it is recommended that fenofibrate be given in the morning and the
Fenofibrate
Drug combination for HIV/AIDS prophylaxis and treatment
United States as part of antiretroviral combination therapy for the treatment of HIV-1. The combination therapy is suggested as one of the options for
Emtricitabine/tenofovir
Medication
antidepressant, it is specifically used as both a monotherapy and combination therapy for treatment-resistant depression (TRD) as well as major depressive
Esketamine
Antiretroviral drug used to treat HIV
used in combination therapy for the treatment of AIDS/HIV. Enfuvirtide is indicated for the treatment of HIV-1 infection, in combination therapy with other
Enfuvirtide
Spanish molecular biochemist (born 1949)
PMID 12923533 – via PubMed. Barbacid, Mariano (2 December 2025). "A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor
Mariano_Barbacid
Mood disorder
This treatment includes cognitive behavioral therapy (CBT), anti-depressant medication, and combination therapy. Research supports the notion that minor depressive
Minor_depressive_disorder
Clinical treatment of skin conditions
Light-emitting diode therapy (LEDT) is a clinical approach that applies different wavelengths of light to cure diseases or conditions with skin-safe lights
Light-emitting_diode_therapy
Anticancer medication
esophageal squamous cell carcinoma. In the same year, the FDA approved a combination therapy consisting of relatlimab and nivolumab for the treatment of some
Nivolumab
Chemical compound
Milani M, Amerio P (August 2004). "Skin tolerability and efficacy of combination therapy with hydrogen peroxide stabilized cream and adapalene gel in comparison
Hydrogen_peroxide
Disorder of the inner ear
disease. However, recent pharmacokinetic experiments have shown that combination therapy with Monoamine oxidase inhibitors can drastically increase the bioavailability
Ménière's_disease
Class of drugs used to treat malignant tumors
certain functional adenocarcinomas, making them commonly used in combination therapies with antineoplastic drugs. Additionally, antineoplastic drugs are
Antineoplastic
CNS stimulant and isomer of amphetamine
cognitive behavioral therapy, 12-step programs, non-contingent reward-based therapies, psychodynamic therapy, and other combination therapies involving these
Dextroamphetamine
Therapy involving intentional exposure to sunlight
Light therapy, also called phototherapy or bright light therapy, is the exposure to direct sunlight or artificial light at controlled wavelengths in order
Light_therapy
Noncancerous increase in size of the prostate gland
Roehrborn CG, et al. (Medical Therapy of Prostatic Symptoms (MTOPS) Research Group) (January 2006). "Combination therapy with doxazosin and finasteride
Benign_prostatic_hyperplasia
medical personnel must approve the abortion. As of 2023, Medabon (a combination therapy containing two medicines called mifepristone and misoprosto) is the
Abortion_in_Cambodia
Species of fungus
in salvage therapy for refractory cases. A case report indicated that voriconazole in combination with amphotericin B as salvage therapy for disseminated
Coccidioides_immitis
Parasitic disease also known as sleeping sickness
is still used today. Resistance to melarsoprol is increasing, and combination therapy with nifurtimox is currently under research. Eflornithine (difluoromethylornithine
African_trypanosomiasis
NeuroIntegration Therapy (NIT) is a non-invasive combination therapy that integrates quantitative electroencephalography (qEEG or QEEG) brain mapping
NeuroIntegration_Therapy
Disease treatment
way of explaining combination therapy.[medical citation needed] There are other theoretical reasons for supporting combination therapy. The different drugs
Management_of_tuberculosis
Monoclonal antibody
myeloma as a combination therapy (second line). Daratumumab phase III trials for multiple myeloma show great promise in combination therapy with lenalidomide
Daratumumab
Group of enantiomers
"Discovery, mechanisms of action and combination therapy of artemisinin". Expert Review of Anti-Infective Therapy. 7 (8): 999–1013. doi:10.1586/eri.09
Lumefantrine
Chemical compound
disease progression. Phase II trials were done to evaluate how NAMI-A in combination with gemcitabine impact cancer progression. 19 patients were added in
NAMI-A
Central nervous system stimulant
cognitive behavioral therapy, 12-step programs, non-contingent reward-based therapies, psychodynamic therapy, and other combination therapies involving these
Methamphetamine
Bempedoic acid/ezetimibe/atorvastatin is a combination therapy composed of bempedoic acid, ezetimibe, and atorvastatin. In a randomized study it showed
Bempedoic acid/ezetimibe/atorvastatin
Bempedoic_acid/ezetimibe/atorvastatin
British academic (born 1950)
Care Research Senior Investigator. Peto's research has included combination therapy for AIDS, the search for an effective AIDS vaccine, the transmission
Tim_Peto
Anti-parasitic medical drug
together with eflornithine in nifurtimox-eflornithine combination treatment as first-line therapy for second-stage gambiense sleeping sickness. In Chagas
Nifurtimox
of antiretroviral therapy, deaths from AIDS have stayed low since the introduction of protease inhibitors and combination therapy in the late 1990s.
HIV/AIDS_in_Europe
Cancer medication
epidermal growth factor receptor (EGFR) pathways. It is used in combination therapy for HER2-positive breast cancer. It is used for the treatment of
Lapatinib
Chemical compound
used in combination with tamoxifen, reduces the uterine hyperplasia and increases the antitumour effects of tamoxifen. A rational combination of AFPep
AFPep
Eye disease affecting the choroid
careful observation, photodynamic therapy, thermal laser, intravitreal injection of anti-VEGF therapy, or combination therapy. In PCV, sudden blurring of vision
Polypoidal choroidal vasculopathy
Polypoidal_choroidal_vasculopathy
Castration via anaphrodisiacal drugs
cognitive behavioral therapy combined with leuprolide acetetate was compared to cognitive behavioral therapy alone, the combination therapy produced a much
Chemical_castration
Medical specialty
fertility for younger patients. The most common route for treatment is combination therapy, consisting of a mix of both surgical and non-surgical interventions
Gynecologic_oncology
2022. Rodney Sinclair (16 May 2015). Female pattern hair loss: Combination therapy with low dose oral minoxidil and spironolactone. 2015 Annual Meeting
Rodney_Sinclair
Chemical compound
inappropriately. It has been researched both as part of a potential combination therapy for some cancers, or alternatively as an antiparasitic, or antiviral
Brequinar
Central nervous system stimulant
cognitive behavioral therapy, 12-step programs, non-contingent reward-based therapies, psychodynamic therapy, and other combination therapies involving these
Amphetamine
Medication used to treat diabetes
(June 2016). "Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes: A Systematic Review and Meta-analysis". Annals
Metformin
Drug mixture used mainly to treat ADHD and narcolepsy
cognitive behavioral therapy, 12-step programs, non-contingent reward-based therapies, psychodynamic therapy, and other combination therapies involving these
Adderall
Blue dye also used as a medication
transmission-stage gametocyte and has synergy with the standard artemisinin-based combination therapy (ACT). Its effects against other malarial species and P. falciparum
Methylene_blue
Chemical compound
Nevirapine in triple combination therapy has been shown to suppress viral load effectively when used as initial antiretroviral therapy (i.e., in antiretroviral-naive
Nevirapine
Pattern seen in radiologic examinations
stimulation. Each of these therapies can be used individually, however, there's greater efficacy and recovery with combination therapy. Conservative treatment's
Scottie_dog_sign
Action to achieve a result in the delivery of healthcare
(TENS) Laser therapy Combination therapy Occupational therapy Immunization Vaccination Immunosuppressive therapy Psychotherapy Drug therapy Acupuncture
Medical_procedure
Inflammatory bowel disease that causes ulcers in the colon
remission was 22% higher if probiotics were used in combination with 5-aminosalicylic acid therapy. It is unclear whether probiotics help to prevent future
Ulcerative_colitis
Chemical compound
artemisinin combination therapy. Piperaquine kills parasites by disrupting the detoxification of host heme. Piperaquine is used in combination with dihydroartemisinin
Piperaquine
Type of therapy to improve mental health
Cognitive behavioral therapy (CBT) is a form of psychotherapy that combines basic principles from cognitive psychology and behaviorism. It aims to reduce
Cognitive_behavioral_therapy
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COMBINATION THERAPY
COMBINATION THERAPY
Girl/Female
Hindu, Indian
Combination of God
Girl/Female
American, Australian, Jamaican
Noble One; Combination Name
Girl/Female
Assamese, Hindu, Indian, Kannada, Tamil
Combination of Meenakshi and Natrajan
Boy/Male
British, English
Combination of Mary and Ann
Girl/Female
American, Australian
Combination Name
Girl/Female
Hindu
Combination of Meenakshi & natrajan
Girl/Female
Hindu, Indian
Combination of Rose and Anna
Boy/Male
British, English
Combination of Ysabel and Anne
Girl/Female
Hindu, Indian, Kannada
Combination
Girl/Female
Indian
Combination of God
Girl/Female
Tamil
Combination of Meenakshi & natrajan
Girl/Female
Arabic, Indian, Pakistani
Combination
Girl/Female
American, British, English
Combination of Ada and Maris
Girl/Female
American, Australian
Combination Name
Girl/Female
Tamil
Sadvita | ஸதà¯à®µà®¿à®¤à®¾
Combination
Sadvita | ஸதà¯à®µà®¿à®¤à®¾
Boy/Male
Indian
Combination of Durga and Ishwar
Girl/Female
Tamil
Combination of rose and Anna
Girl/Female
Christian & English(British/American/Australian)
Combination of Lee & Anne
Boy/Male
Indian, Tamil
Combination of Lord Krishna / Shiva
Girl/Female
American, Australian, French
Combination of Lana and Elle
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
COMBINATION THERAPY
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