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DDX6

  • DDX6
  • Protein-coding gene in the species Homo sapiens

    Probable ATP-dependent RNA helicase DDX6 is an enzyme that in humans is encoded by the DDX6 gene. DEAD box proteins, characterized by the conserved motif

    DDX6

    DDX6

    DDX6

  • Decapping complex
  • Eukaryotic protein complex that removes the 5' cap on mRNA

    proteins such as Xrn1, Upf1, Upf2, Upf3, the LSm complex, and the Dhh1 ortholog DDX6. Proteins unique to plants and mammals include the beta propeller protein

    Decapping complex

    Decapping complex

    Decapping_complex

  • P-bodies
  • Biomolecular condensates of mRNA and RNA binding proteins found in eukaryotic cells

    SMG7 SMG7 Yes AGO1 AGO1 Yes LGALS7 LEG7 No MYO1D MYO1D No XRCC5 XRCC5 No DDX6 DDX6/p54/RCK Yes ZC3HAV1 ZCCHV Yes DDX27 DDX27 No NUMA1 NUMA1 No DSG1 DSG1

    P-bodies

    P-bodies

  • Stress granule
  • Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

    et al. (April 2007). "Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules". Molecular Biology of the

    Stress granule

    Stress granule

    Stress_granule

  • DHX30 syndrome
  • Rare genetic disorder

    helicase genes involved in similar developmental disorders include DDX3X, DDX6, EIF4A2, DDX23, DDX54, DDX59, EIF4A3, DHX9, DHX37, DHX16, and DHX34. Lessel

    DHX30 syndrome

    DHX30_syndrome

  • RNA helicase
  • NS3 helicase, DBP2, DbpA, DDX17, DDX25, DDX3, DDX3X, DDX3Y, DDX4, DDX5, DDX6, DDX23, DDX54, DDX59, DEAD-box protein DED1, DEAD-box RNA helicase, DEAD-box

    RNA helicase

    RNA helicase

    RNA_helicase

  • Helicase
  • Class of enzymes that unpack genetic material

    CHD5, CHD6, CHD7, CHD8, CHD9 DEAD box/DEAD/DEAH box helicase: DDX3X, DDX5, DDX6, DDX10, DDX11, DDX12, DDX58, DHX8, DHX9, DHX37, DHX40, DHX58, DHX30 ASCC3

    Helicase

    Helicase

    Helicase

  • DHX30
  • Gene and Protein

    (DHX9, DHX30, DHX37, DHX16, and DHX34) and 7 DEAD-box RNA helicases (DDX3X, DDX6, EIF4A2, DDX23, DDX54, DDX59, and EIF4A3). DHX30, as with many DEAD/DEAH-box

    DHX30

    DHX30

    DHX30

  • CNOT9
  • Protein-coding gene in humans

    "Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression". Mol. Cell. 54 (5): 751–65. doi:10.1016/j

    CNOT9

    CNOT9

    CNOT9

  • List of human protein-coding genes 2
  • HGNC:2699; O15523 4072 DDX4 HGNC:18700; Q9NQI0 4073 DDX5 HGNC:2746; P17844 4074 DDX6 HGNC:2747; P26196 4075 DDX10 HGNC:2735; Q13206 4076 DDX11 HGNC:2736; Q96FC9

    List of human protein-coding genes 2

    List_of_human_protein-coding_genes_2

  • Witold Filipowicz
  • Polish-Swiss biochemist and molecular biologist

    "Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression". Molecular Cell. 54 (5): 751–765. doi:10.1016/j

    Witold Filipowicz

    Witold_Filipowicz

  • DDX1
  • Protein-coding gene in the species Homo sapiens

    Yagi K, Nishi Y (April 1999). "Expression of two dead box genes (DDX1 and DDX6) is independent of that of MYCN in human neuroblastoma cell lines". Biochemistry

    DDX1

    DDX1

    DDX1

  • ATXN2L
  • Protein-coding gene in the species Homo sapiens

    Welzel F, et al. (2007). "Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules". Mol. Biol. Cell. 18 (4):

    ATXN2L

    ATXN2L

    ATXN2L

  • MiR-122
  • RNA family

    molecular behavior of Ago2. Another miRISC component, the DEAD-box RNA helicase DDX6, does not play a role in miR-122-facilitated HCV replication. The existing

    MiR-122

    MiR-122

    MiR-122

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