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Protein coding gene in Humans
initiation factor 4A-I (also known as eIF4A1 or DDX2A) is a 46 kDa cytosolic protein that, in humans, is encoded by the EIF4A1 gene, which is located on chromosome
EIF4A1
Multiprotein complex used in gene expression
Subunit MW (kDa)[A] Isoforms Key Features eIF4A 46 eIF4A1, eIF4A2, eIF4A3 DEAD-box RNA helicase. Binds mRNA, eIF4G, eIF4B, eIF4H, and PDCD4. Inhibited
Eukaryotic initiation factor 4F
Eukaryotic_initiation_factor_4F
Protein family
initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA
EIF4A
Human chromosome
CD300E, CD300LB, CD300LD, CD300LF, CD300LG DEAD box helicases: DDX2A (EIF4A1), DDX5, DDX42, DDX48 (EIF4A3), DDX52 FOX (forkhead box) proteins: FOXJ1
Chromosome_17
Protein-coding gene in the species Homo sapiens
layer, CTIP2-expressing ones. Moreover, IRE1α controls the proteostasis of eIF4A1 to drive translation of neuronal subtype determinants. GRCh38: Ensembl release
ERN1
Protein-coding gene in the species Homo sapiens
Miyashita A, Shimizu N, Endo N, et al. (1999). "Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse
SOX15
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
contain many RNA helicases, including the DEAD/H-box helicases Ded1p/DDX3, eIF4A1, and RHAU. In yeast, catalytic ded1 mutant alleles give rise to constitutive
Stress_granule
Gene which maintains basic cellular functions
formerly EIF3S4 EIF3G EIF3I EIF3H EIF3J EIF3K EIF3L EIF3M EIF3S5 EIF3S8 EIF4A1 EIF4A2 EIF4A3 EIF4E2 EIF4G1 EIF4G2 EIF4G3 EIF4H EIF5 EIF5 EIF5A EIF5AL1
Housekeeping_gene
Q9UBQ5 4836 EIF3L HGNC:18138; Q9Y262 4837 EIF3M HGNC:24460; Q7L2H7 4838 EIF4A1 HGNC:3282; P60842 4839 EIF4A2 HGNC:3284; Q14240 4840 EIF4A3 HGNC:18683;
List of human protein-coding genes 3
List_of_human_protein-coding_genes_3
Protein-coding gene in the species Homo sapiens
translation initiation factor 4 gamma has been shown to interact with MKNK1, EIF4A1, EIF4E, MKNK2 and PABPC1. Eukaryotic initiation factor GRCh38: Ensembl release
Eukaryotic translation initiation factor 4 gamma 1
Eukaryotic_translation_initiation_factor_4_gamma_1
Protein-coding gene in the species Homo sapiens
surface that is used experimentally. EIF4E has been shown to interact with: EIF4A1, EIF4EBP1, EIF4EBP2, EIF4EBP3, EIF4ENIF1, EIF4G1, and EIF4G2. Other direct
EIF4E
RNA family
ACA48 and U67, and the C/D box snoRNA mgU6-77, share the same host gene (EIF4A1). Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation
Small_nucleolar_RNA_SNORA48
RNA family
U1445 in 18S rRNA. This RNA is expressed from the intron of the host gene EIF4A1. Kiss, T (2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs
Small_nucleolar_RNA_SNORA67
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