Searches , social queries for ENE REDUCTASE
Search references for ENE REDUCTASE. Phrases containing ENE REDUCTASE
See searches and references containing ENE REDUCTASE!
Search references for ENE REDUCTASE. Phrases containing ENE REDUCTASE
See searches and references containing ENE REDUCTASE!ENE REDUCTASE
Class of enzymes
Ene-reductase (ER, ERED) is an enzyme able to catalyze the stereoselective reduction of carbon-carbon double bonds (C=C) that are activated by electron
Ene-reductase
Use of natural catalysts to perform chemical transformations
medium sized lactams can be synthesized in the chiral environment of an ene-reductase through a reductive, baldwin favored, radical cyclization terminated
Biocatalysis
Reaction in organic chemistry
functionality of ene reductases emphasizes their crucial role in catalyzing a variety of reactions. One example is the ene-reductase Old-Yellow-Enzyme
Group_transfer_reaction
Enzyme family
steroid reductase Δ4-3-Ketosteroid-5α-oxidoreductase Δ4-3-Oxosteroid-5α-reductase 3-Keto-Δ4-steroid-5α-reductase Testosterone 5α-reductase 4-Ene
5α-Reductase
Antiandrogen and hormone replacement medication
between 5α-reductase inhibitors and prostate cancer has been established. This is not due to a direct link between dutasteride or other 5α-reductase inhibitors
Dutasteride
Class of enzymes
Delta4-hydrogenase, 4-ene-3-oxosteroid 5alpha-reductase, reduced nicotinamide adenine dinucleotide, phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase, 4-ene-5alpha-reductase
Cholestenone_5alpha-reductase
Enzyme found in humans
enzyme that in humans is encoded by the HSD3B7 gene. Also called cholest-5-ene-3β,7α-diol 3β-dehydrogenase (EC 1.1.1.181), this enzyme catalyzes several
HSD3B7
Chemical compound
and MK-434 on the kinetics of pig testis microsomal testosterone-4-ene-5alpha-reductase activity". J. Steroid Biochem. Mol. Biol. 60 (5–6): 353–9. doi:10
MK-434
Chemical compound
FCE 28260 is an azasteroidal 5α-reductase inhibitor which was developed for the treatment of benign prostatic hyperplasia and androgenic alopecia (pattern
FCE_28260
Chemical compound
FrzF), an ene-reductase (OYE, FrzD), a nonheme, iron and α-ketoglutarate dependent oxygenase (αKG, FrzG), two short-chain dehydrogenase/reductases (SDRs,
FR901483
Endogenous weak androgen
4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate
Androstenedione
Antiandrogen medication
specifically on hair follicles. Finasteride is a widely dispensed 5α-reductase inhibitor. As such, it is an antiandrogen that works by decreasing the
Finasteride
Class of enzymes
1-ene-dehydrogenase, 3-oxosteroid:(2,6-dichlorphenolindophenol) Delta1-oxidoreductase, 4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase, Delta1-steroid
3-oxosteroid_1-dehydrogenase
Steroid drug
"4-Methyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-N-aryl-carboxamides: an approach to combined androgen blockade [5alpha-reductase inhibition with androgen receptor
Cl-4AS-1
Class of enzymes
Other names in common use include: progesterone reductase Δ5-3β-hydroxysteroid dehydrogenase 3β-hydroxy-5-ene steroid dehydrogenase 3β-hydroxy steroid
3β-Hydroxysteroid dehydrogenase
3β-Hydroxysteroid_dehydrogenase
Abandoned drug
"4-Methyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-N-aryl-carboxamides: an approach to combined androgen blockade [5alpha-reductase inhibition with androgen receptor
TFM-4AS-1
Chemical compound
Chloromethylandrostenediol (CMA), also known as 4-chloro-17α-methyl-androst-4-ene-3β,17β-diol, is a synthetic, orally active anabolic-androgenic steroid (AAS)
Chloromethylandrostenediol
Sex hormone
The major metabolic pathway of progesterone is reduction by 5α-reductase and 5β-reductase, into the dihydrogenated 5α-dihydroprogesterone and 5β-dihydroprogesterone
Progesterone
Polycyclic organic compound having sterane as a core structure
pregn-4-ene-11β,17α-diol-3,20-dione or androst-4-ene-3,11,17-trione. The double bond is designated by the lower-numbered carbon atom, i.e. "Δ4-" or "4-ene" means
Steroid
Organic compound used as flavouring and analgesic
(+)-pulegone. (+)-Pulegone reductase (PR) reduces this double bond using NADPH to form (−)-menthone. (−)-Menthone reductase (MR) then reduces the carbonyl
Menthol
Vertebrate natural glucocorticoid hormone
reactions for which 5-alpha reductase and 5-beta-reductase are the rate-limiting factors, respectively. 5-Beta reductase is also the rate-limiting factor
Cortisol
Functional group of organic compounds
containing thiol groups may protect from such harmful alkylation. 2-alkenal reductase Dicarbonyls Enol Patai, Saul; Rappoport, Zvi, eds. (1989). Enones. Patai's
Α,β-Unsaturated carbonyl compound
Α,β-Unsaturated_carbonyl_compound
Chemical compound
Stenandiol), or 5-androstenediol 3β,17β-dipropionate, also known as androst-5-ene-3β,17β-diol 3β,17β-dipropionate, is a synthetic anabolic–androgenic steroid
Androstenediol_dipropionate
Class of drugs
local conversion via 5α-reductase into DHT in tissues where 5α-reductase is expressed, an AAS that is not metabolized by 5α-reductase or is already 5α-reduced
Anabolic_steroid
EC 1.1.1.180: Now included with EC 1.1.1.131 mannuronate reductase EC 1.1.1.181: cholest-5-ene-3β,7α-diol 3β-dehydrogenase EC 1.1.1.182: Now included with
List_of_EC_numbers_(EC_1)
Mammalian pheromone also found in truffles
3β-hydroxysteroid dehydrogenase (androstadienol to androstadienone), 5α-reductase (androstadienone to androstenone), and 3α-hydroxysteroid dehydrogenase
Androstenol
Chemical compound
related structurally to androstenediol (androst-5-ene-3β,17β-diol), androstenedione (androst-4-ene-3,17-dione), and testosterone (androst-4-en-17β-ol-3-one)
Dehydroepiandrosterone
Anti-diabetic and anti-obesity medication
Kavianinia I, Harris PW, Brimble MA (January 2021). "Photo-induced radical thiol-ene chemistry: a versatile toolbox for peptide-based drug design". Chemical Society
Tirzepatide
Pharmaceutical drug
hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse)
Cefotetan
Chemical compound
Androstenediol 3β-acetate, or 5-androstenediol 3β-acetate, also known as androst-5-ene-3β,17β-diol 3β-acetate, is a synthetic anabolic-androgenic steroid and an
Androstenediol_3β-acetate
Prohormone of an anabolic-androgenic steroid
17β-dihydroxyestr-4-ene) 19-Nor-4-androstenediol (3α,17β-dihydroxyestr-4-ene) 19-Nor-5-androstenediol (3β,17β-dihydroxyestr-5-ene and 3α,17β-dihydroxyestr-5-ene) Norandrostenedione
Androgen_prohormone
2-Dithiolene ligands can exist in three oxidation states: the dianionic "ene-1,2-dithiolate", the neutral "1,2-dithioketone," and a monoanionic radical
Metal_dithiolene_complex
Chemical compound
HOCPCA Names Preferred IUPAC name 3-Hydroxycyclopent-1-ene-1-carboxylic acid Identifiers CAS Number 867178-11-8 Y 3D model (JSmol) Interactive image ChEMBL
HOCPCA
Progestin medication
adverse effects described. 5α-Reductase plays an important role in the metabolism of norethisterone, and 5α-reductase inhibitors such as finasteride
Norethisterone
Medication
Desogestrel and etonogestrel show some albeit weak inhibition of 5α-reductase (5.7% inhibition at 0.1 μM, 34.9% inhibition at 1 μM) and cytochrome P450
Desogestrel
disulfides: 2 RS· → RS−SR Thiyl radicals are intermediates in the thiol-ene reaction, which is the basis of some polymeric coatings and adhesives. Thiyl
Thiyl_radical
Chemical compound
Androstenediol 17β-acetate, or 5-androstenediol 17β-acetate, also known as androst-5-ene-3β,17β-diol 17β-acetate, is a synthetic anabolic-androgenic steroid and an
Androstenediol_17β-acetate
Injectable form of birth control
allopregnanolone, and pregnanolone (catalyzed by the enzymes 5α- and 5β-reductase and 3α- and 3β-HSD), is a positive allosteric modulator of the GABAA receptor
Medroxyprogesterone_acetate
molybdenum oxotransferases that also includes DMSO reductase, xanthine oxidase, and nitrite reductase. In mammals, the expression levels of sulfite oxidase
Sulfite_oxidase
Chemical compound
Lapisteride (INN; CS-891) is a dual inhibitor of both isoforms of the enzyme 5α-reductase. It was under investigation for the treatment of benign prostatic hyperplasia
Lapisteride
Chemotherapy medication
Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)
Docetaxel
Steroidal antiandrogen and antimineralocorticoid
names: 7α-Acetylthio-17α-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone 7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17β-carbolactone 3-(3-Oxo-7α-acetylth
Spironolactone
Chemical compound
Bolandiol (INN, also known as 19-nor-4-androstenediol, estr-4-ene-3β,17β-diol, or 3β-dihydronandrolone) is an anabolic-androgenic steroid (AAS) that was
Bolandiol
Hydrocarbon compound (CH4) in natural gas
final step in the process is catalyzed by the enzyme methyl coenzyme M reductase (MCR). Wetlands are the largest natural sources of methane to the atmosphere
Methane
Chemical compound
3 it is sterically favored to form a single stereomere by execution of a Ene-reaction. The alcohol or ester that is formed can be removed by presence
Xanthatin
Chemical compound
21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone CAS Number 128517-07-7 N PubChem CID 5352062 IUPHAR/BPS
Romidepsin
Antibiotic medication
hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse)
Cefazolin
Corticosteroid medication
beta-hydroxysteroid dehydrogenases (11[beta]-HSD) and 20-ketosteroid reductases. Methylprednisolone undergoes renal excretion of hydrophilic inactive
Methylprednisolone
Medication and naturally occurring steroid hormone
occurring pregnane steroid and is also known as pregn-4-ene-3,20-dione. It has a double bond (4-ene) between the C4 and C5 positions and two ketone groups
Progesterone_(medication)
Endogenous inhibitory neurosteroid
with the conversion of progesterone into 5α-dihydroprogesterone by 5α-reductase. After that, 3α-hydroxysteroid dehydrogenase converts this intermediate
Allopregnanolone
Stereogenic group placed on a molecule to encourage stereoselectivity in reactions
James K. Whitesell and coworkers in 1985. This chiral auxiliary was used in ene reactions of the derived ester of glyoxylic acid. In the total synthesis
Chiral_auxiliary
Chemical compound
17α-methylandrost-5-ene-3β,17β-diol, is a synthetic androstane steroid and a 17α-alkylated derivative of 5-androstenediol (androst-5-ene-3β,17β-diol). A number
Methandriol
Progestin medication
containing desogestrel. Gestodene may also act to some extent as a 5α-reductase inhibitor. Taken together, like desogestrel, gestodene appears to have
Gestodene
Hormonal medication used for birth control
5α-Dihydrolevonorgestrel is produced as an active metabolite of levonorgestrel by 5α-reductase. The elimination half-life of levonorgestrel is 24 to 32 hours, although
Levonorgestrel
Chemical compound
ethynylandrostanediol (HE-3235). Its formation from its parent drugs is catalyzed by 5α-reductase in tissues that express the enzyme in high amounts like the liver, skin
5α-Dihydroethisterone
Yellow pigment in urine
urobilinogen. The enzyme responsible for the degradation is bilirubin reductase, which was identified in 2024. Some of this remains in the large intestine
Urobilin
Antibiotic
hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse
Cefoperazone
Chemical compound
Gestonorone caproate has been reported to act to some extent as a 5α-reductase inhibitor, similarly to progesterone. Like the closely related progestins
Gestonorone_caproate
Chemical compound
[514-61-4] (5) in 40% yield. In an alternative synthesis, reaction of Estr-5(10)-ene-3,17-dione [3962-66-1] (3) with methanol catalyzed by malonic acid gave a
Mibolerone
Chemical compound
hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse)
Cefamandole
Medication producing effects similar to progesterone
and inducers of cytochrome P450 enzymes and other enzymes such as 5α-reductase may interact with progestogens.[citation needed] Progestogens act by binding
Progestogen_(medication)
Chemical compound
metabolism in healthy young adults: sexual dimorphism in activities of A-ring reductases, but not 11beta-hydroxysteroid dehydrogenases". J Clin Endocrinol Metab
6β-Hydroxycortisol
Protein-coding gene in the species Homo sapiens
glutathione, which usually acts as a redox coenzyme. Although aldose reductase can also detoxify methylglyoxal, the glyoxalase system is more efficient
Lactoylglutathione_lyase
Chemical compound
to chanoclavine-l-aldehyde, catalyzed by the short-chain dehydrogenase/reductase (SDR), EasD. From here, the biosynthesis diverges and the products formed
Ergine
with Jones reagent to afford androst-4-ene-3,17-dione with a 73% yield. Step 2 is hydroxylation of androst-4-ene-3,17-dione with OsO4 followed by step
Steroidal_aromatase_inhibitor
Medical usage of the prasterone compound
related structurally to androstenediol (androst-5-ene-3β,17β-diol), androstenedione (androst-4-ene-3,17-dione), and testosterone (androst-4-en-17β-ol-3-one)
Prasterone
Chemical compound
diacetate, or 5-androstenediol 3β,17β-diacetate, also known as androst-5-ene-3β,17β-diol 3β,17β-diacetate, is a synthetic anabolic-androgenic steroid
Androstenediol_diacetate
Chemical compound
hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram, due
Cefmetazole
Chemical compound
(JAN), norpropandrolate, 19-nor-4-androstenediol dipropionate, or estr-4-ene-3β,17β-diol 3,17-dipropionate) is a synthetic anabolic-androgenic steroid
Bolandiol_dipropionate
Austrian professor of organic chemistry (born 1939)
Bilindione-10-Thiol-Adduct as a Model for the Reduction Step of the Biliverdin Reductase System. Monatsh. Chem. 122, 319 (1991) U. Wagner, C. Kratky, H. Falk und
Heinz_Falk
Dopamine agonist medication
Saxagliptin Sitagliptin Teneligliptin Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase
Bromocriptine
Chemical compound
methylandrostenediol bisenanthoyl acetate, also known as 17α-methylandrost-5-ene-3β,17β-diol 3β,17β-di(3-oxononanoate), is a synthetic, injected anabolic–androgenic
Methandriol bisenanthoyl acetate
Methandriol_bisenanthoyl_acetate
Medication drug
2-dihydrospirorenone or as 17β-hydroxy-6β,7β:15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21-carboxylic acid, γ-lactone, is a synthetic steroidal 17α-spirolactone
Drospirenone
Chemical compound
lacking the keto group at the C3 position (part of the important 3-keto-4-ene structure) that is common in progestogens and is considered to be necessary
Allylestrenol
Progestin medication
16-methylene-17α-acetoxy-19-norprogesterone or as 16-methylene-17α-acetoxy-19-norpregn-4-ene-3,20-dione, is a synthetic norpregnane steroid and a derivative of progesterone
Segesterone_acetate
Chemical compound
second 6-member ring forms and agroclavine is obtained after additional reductase (Steps G and H). Finally elymoclavine is generated after an oxidation
Elymoclavine
Chemical compound
acyltransferase, KR is keto ACP reductase, KR with cross is inactive KR, DH is hydroxyl-thioester dehydratase, ER is enoyl reductase, TEI is thioesterase domain
Pikromycin
Pharmaceutical drug
2-3H2]medroxyprogesterone acetate (17-alpha-acetoxy-6-alpha-methyl[1,2-3H2]pregn-4-ene-3,20-dione) and [1,2-3H2]megestrol acetate (17-alpha-acetoxy-6-methyl[1,2-3H2]pregna-4
Megestrol_acetate
Chemical compound
Reed MJ, Purohit A (July 2006). "Lack of aromatisation of the 3-keto-4-ene metabolite of tibolone to an estrogenic derivative". Steroids. 71 (7): 639–646
Tibolone
Chemical compound
3β-propionate; 17α-Ethyl-19-nortestosterone 3β-propionate; 19-Nor-17α-pregn-4-ene-3β,17β-diol 3β-propionate; Norethandrolone 3β-propionate Routes of administration
Propetandrol
Chemical compound
17β-diaceate, 3β-hydroxynorethisterone 3β,17β-diacetate, or 17α-ethynylestr-4-ene-3β,17β-diol 3β,17β-diacetate, is a synthetic estrane steroid and a derivative
Etynodiol_diacetate
Abandoned drug
or glucocorticoid receptor and shows no significant inhibition of 5α-reductase (IC50 > 10 μM). In addition, it is non-aromatizable and hence has no potential
MK-0773
Chemical compound
pharmacological differences. Progesterone is metabolized by 5α- and 5β-reductases, 3α- and 3β-hydroxysteroid dehydrogenases, and 20α- and 20β-hydroxysteroid
Hydroxyprogesterone_caproate
Chemical compound
dipropionate; Methylandrostenediol 3β,17β-dipropionate; MADP; 17α-Methylandrost-5-ene-3β,17β-diol 3,17β-dipropionate Routes of administration Intramuscular injection
Methandriol_dipropionate
Chemical compound
Metilbisexovis), or methylandrostenediol propionate, also known as 17α-methylandrost-5-ene-3β,17β-diol 3β-propionate, is a synthetic, injected anabolic-androgenic steroid
Methandriol_propionate
Chemical compound
17β-cyclopent-1-enyl enol ether or as androsta-1,4-dien-17β-ol-3-one 17β-(1-cyclopent-1-ene) enol ether, is a synthetic androstane steroid and a derivative of testosterone
Quinbolone
Protein-coding gene in humans
"Synonymous polymorphism in the coding sequence of human 3-beta hydroxysteroid-5-ene dehydrogenase (HSD)". Nucleic Acids Research. 19 (5): 1172. doi:10.1093/nar/19
HSD3B1
6-bisphosphate 2-phosphatase EC 3.1.3.47: [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase EC 3.1.3.48: protein-tyrosine-phosphatase EC 3.1
List_of_EC_numbers_(EC_3)
travel, tourism, insurance
ENE REDUCTASE
ENE REDUCTASE
ENE REDUCTASE
ENE REDUCTASE
ENE REDUCTASE
ENE REDUCTASE
ENE REDUCTASE
ENE REDUCTASE
ENE REDUCTASE
travel, tourism, insurance