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Opioid medication
Fentanyl is a highly potent synthetic opioid of the piperidine family, used primarily as pain medication. It is 50 to 100 times more potent than morphine
Fentanyl
Chemical compound
despropionyl fentanyl, is a direct precursor to fentanyl and acetylfentanyl. It is commonly found as a contaminant in samples of drugs containing fentanyl, which
4-ANPP
Ongoing overuse of opioid medication in the US
illegally-made fentanyl; as the statistics on overdose deaths (as of 2015) do not distinguish pharmaceutical fentanyl from illegally-made fentanyl, the actual
Opioid epidemic in the United States
Opioid_epidemic_in_the_United_States
Misuse of opioid medications in California, United States
to synthetic opioids increased by 1,027% (almost eleven-fold). In 2023, fentanyl, a particularly potent opioid that often contaminates other recreational
California_opioid_crisis
Comprehensive list of compounds structurally related to fentanyl
The following is a list of fentanyl analogues (sometimes referred to as fentalogs), and includes both compounds developed by pharmaceutical companies for
List_of_fentanyl_analogues
Glass pipe associated with recreational drug use
battle the rising use of methamphetamine. A fentanyl pipe is a hammer-shaped pipe used to smoke fentanyl, which is often sold in "chunks". A love rose
Drug_pipe
Transnational drug-trafficking organization
synthesize fentanyl and its analogues come from China where it is then processed into actual fentanyl by criminal organizations in Mexico. Fentanyl is chemically
Sinaloa_Cartel
Overview of present and pending US laws targeting fentanyl
the Democratic Party. Only the END FENTANYL Act and the HALT Fentanyl Act have been signed into law. The Stop Fentanyl Border Crossings Act is pending United
Anti-fentanyl legislation in the United States
Anti-fentanyl_legislation_in_the_United_States
Chemical compound
Fentanyl carbamate (Fentanyl ethyl carbamate, Fentanyl ethylformate) is an opioid analgesic that is an analog of fentanyl and has been sold as a designer
Fentanyl_carbamate
Opioid analgesic
Acetylfentanyl (acetyl fentanyl) is an opioid analgesic drug that is an analog of fentanyl. Studies have estimated acetylfentanyl to be 15 times more
Acetylfentanyl
Chemical compound
Fentanyl azepane (Fentanyl azepane homologue) is an opioid derivative which is a homologue of fentanyl, where the central piperidine ring has been expanded
Fentanyl_azepane
American rapper (1992–2018)
referenced in his lyrics. He died from an accidental drug overdose of cocaine, fentanyl, and alcohol at his home at the age of 26. Malcolm James McCormick was
Mac_Miller
Synthetic opioid analgesic
potent short-acting synthetic opioid analgesic drug. It is an analog of fentanyl with around one quarter of its potency. One of the first mentions of this
Butyrfentanyl
Placement of cyclopentyl fentanyl, isobutyryl fentanyl, para-chloroisobutyryl fentanyl, para-methoxybutyryl fentanyl, and valeryl fentanyl in Schedule I; Correction"
List of Schedule I controlled substances (U.S.)
List_of_Schedule_I_controlled_substances_(U.S.)
Opioid analgesic
Cyclopropylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug. Between June and December 2017, a total
Cyclopropylfentanyl
Combination of narcotics
of cocaine and heroin; however, methamphetamine mixed with morphine or fentanyl has also been used. A speedball may be taken intravenously or by nasal
Speedball_(drug)
2022 Canadian film
Love in the Time of Fentanyl is a 2022 documentary film by Colin Askey, about group of people who operate a safe injection site in the Downtown Eastside
Love_in_the_Time_of_Fentanyl
Synthetic opioid analgesic metabolite and precursor
is an analog and metabolite of fentanyl with the removal of the phenethyl moiety (or functional group) from fentanyl chemical structure. Norfentanyl
Norfentanyl
Opioid analgesic
Isobutyrylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold online as a designer drug. It is believed to be around the same
Isobutyrylfentanyl
Mexican drug trafficker (born 1986)
Sinaloa Cartel and its fentanyl trafficking operations, including: coordination of fentanyl trafficking into the U.S.; shipping fentanyl precursor chemicals
Jesús_Alfredo_Guzmán_Salazar
2026 American crime drama series
trafficking-turned-serial killer who kills wealthy men using lethal doses of fentanyl Quincy Tyler Bernstine as Nora Washington, the head of the FBI's sex crimes
Furious_(TV_series)
Opioid analgesic
is an analog of fentanyl, and has been sold online as a designer drug. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include
4-Chloroisobutyrylfentanyl
2024 film by John Swab
star in a gritty action crime thriller about the dangerous underworld of fentanyl cartels in middle America. Work hits too close to home for a drug cop when
King_Ivory
Chemical compound
Fentanyl tropane (tropafentanyl) is an opioid derivative which is an analogue of fentanyl, where the central piperidine ring has been bridged with a two
Fentanyl_tropane
Opioid analgesic
is an analog of fentanyl and has been sold online as a designer drug. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include
Methoxyacetylfentanyl
Chemical compound
chemicals and pharmaceutical drugs such as fentanyl. Because of its possible use in the illicit manufacture of fentanyl, the United States Drug Enforcement Administration
N-Phenethyl-4-piperidinone
Opioid analgesic
(or alpha-Methylfentanyl, α-MF) an opioid analgesic that is an analog of fentanyl. It is sometimes sold as "China White". α-Methylfentanyl was discovered
Α-Methylfentanyl
American actor (1988–2023)
treatment for drug addiction in 2021. Ellingson died from a suspected fentanyl overdose in Fontana, California, on November 5, 2023. He was 35. According
Evan_Ellingson
2025 British crime drama television series
as Jaime Lopez (season 1), the leader of a Mexican cartel involved in fentanyl production Toby Jones as Colin Tattersall, a retired DCI tasked with taking
MobLand
Opioid analgesic
also known as phenylfentanyl, is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug. In the United States, benzoylfentanyl
Benzoylfentanyl
Opioid designer drug
(N-phenylpropylnorfentanyl, fentanyl propyl analogue) is an opioid derivative which has been sold as a designer drug. It is a homologue of fentanyl, with similar analgesic
Homofentanyl
Synthetic opioid
spirochlorphine, and is claimed to be an opioid with a similar potency to fentanyl, but no pharmacological data for cychlorphine have been published. It is
Cychlorphine
Class of drugs
centrally active, selective μ-opioid receptor agonists. The high potency of fentanyl (in humans) is matched by a few nitazenes and surpassed by etonitazene
Nitazenes
2018 execution in Nebraska
execution since 1997. The execution was the first in the United States to use fentanyl. The execution took place on August 14, 2018, at the Nebraska State Penitentiary
Execution_of_Carey_Dean_Moore
American politician (born 1986)
opioid fentanyl as a weapon of mass destruction. A Congressional Research Service report released in March stated that "formally designating fentanyl as [a
Lauren_Boebert
Synthetic opioid analgesic
rhinoceroses. It is a structural analogue of the synthetic opioid analgesic fentanyl. It is typically administered in this context by tranquilizer dart. Carfentanil
Carfentanil
Opioid analgesic
It is slightly less potent than fentanyl in rats. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea
Phenaridine
Opioid analgesic
analog of fentanyl and has been sold online as a designer drug. While the structural isomer p-fluorofentanyl was one of the first illicit fentanyl analogues
Orthofluorofentanyl
Opioid analgesic
Valerylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold online as a designer drug. It has been seldom reported on illicit
Valerylfentanyl
Opioid analgesic
analog of fentanyl and has been sold online as a designer drug, mainly in Sweden and other Scandinavian countries. Side effects of fentanyl analogs are
Cyclopentylfentanyl
Synthetic opioid
also called A-3217) is a potent synthetic opioid structurally related to fentanyl that was developed in the early 1990s as one of a series of potent naloxone-reversible
Ocfentanil
Chemical compound
analog of fentanyl and has been sold as a designer drug, first identified in Pennsylvania in the US in March 2020. The effects of fentanyl analogs are
4-Bromofentanyl
Opioid analgesic
3-Methylfentanyl (3-MF, mefentanyl) is an opioid analgesic that is an analog of fentanyl. 3-Methylfentanyl is one of the most potent opioids, estimated to be between
3-Methylfentanyl
American actress and singer (1989–2026)
involving fentanyl, coroner says". Shafer, Ellise (September 22, 2026). "Hayden Panettiere's Cause of Death Revealed as Toxic Effects of Fentanyl and More;
Hayden_Panettiere
Opioid analgesic
(4-fluorofentanyl, para-fluorofentanyl, pFF) is an opioid analgesic analogue of fentanyl developed by Janssen Pharmaceuticals in the 1960s. Parafluorofentanyl was
Parafluorofentanyl
Chinese drug manufacturer
indicted by the United States Justice Department for crimes relating to fentanyl, xylazine and methamphetamine production, distribution of synthetic opioids
Hanhong Pharmaceutical Technology
Hanhong_Pharmaceutical_Technology
Opioid analgesic
is an opioid analgesic that is an analogue of fentanyl. 3-Allylfentanyl has effects similar to fentanyl, although it is only 0.13x-0.14x as potent by
3-Allylfentanyl
N-(2C-B) fentanyl N-(2C-C) fentanyl N-(2C-D) fentanyl N-(2C-E) fentanyl N-(2C-G) fentanyl N-(2C-H) fentanyl N-(2C-I) fentanyl N-(2C-IP) fentanyl N-(2C-N)
List_of_designer_drugs
Opioid analgesic
β-Hydroxyfentanyl is an opioid analgesic that is an analogue of fentanyl. β-Hydroxyfentanyl was sold briefly on the black market in the early 1980s, before
Β-Hydroxyfentanyl
Veterinary anesthetic, sedative and analgesic
territory of Puerto Rico. The drug is used as a cutting agent for heroin and fentanyl. Xylazine was discovered as an antihypertensive agent in 1962 by Farbenfabriken
Xylazine
Mexican criminal organization
the organization is primarily involved in the distribution of cocaine, fentanyl, and methamphetamine to the United States, but it is also involved in growing
La Nueva Familia Michoacana Organization
La_Nueva_Familia_Michoacana_Organization
American medical television drama series
parents of teenager Nick Bradley that their son is brain-dead due to a fentanyl overdose. He prescribes unnecessary tests to allow them more time to process
The_Pitt
Opioid analgesic
3R,4S,βS-ohmefentanyl, was 28 times more powerful as a painkiller than fentanyl, the chemical from which it is derived, and 6300 times more powerful than
Ohmefentanyl
Opioid analgesic
analog of fentanyl and has been sold online as a designer drug, first appearing in Europe in late 2016. It has somewhat lower potency than fentanyl itself
Tetrahydrofuranylfentanyl
Canadian actor (2003–2020)
for treatment bed. His cause of death was later determined as accidental fentanyl overdose. He was survived by his mother, father Clive, and grandparents
Logan_Williams
Medicated adhesive patch
containing opioids such as buprenorphine and fentanyl, used to relieve moderate to severe pain. Fentanyl is often used for opioid-tolerant patients. Nitroglycerin
Transdermal_analgesic_patch
American actor (2004–2022)
Los Angeles on June 16, 2022, at the age of 18, following an accidental fentanyl overdose. The 2022 film The Price We Pay, in which he played the role of
Tyler_Sanders
Opioid analgesic
3-Methylthiofentanyl is an opioid analgesic and analogue of fentanyl. 3-Methylthiofentanyl was sold briefly on the black market in the early 1980s, before
3-Methylthiofentanyl
Toxic chemical agent used by Russian special forces
originally thought by some sources to be a derivative of the potent opioid fentanyl, most probably 3-methylfentanyl dissolved in an inhalational anaesthetic
Kolokol-1
Second election of Donald Trump
officials, and their families, with some receiving letters laced with fentanyl. As of March 2024, the Department of Justice's Election Threats Task Force
2024 United States presidential election
2024_United_States_presidential_election
2022 murder in Utah, U.S.
39‑year‑old American man living in Utah, died from a lethal dose of illicit fentanyl. On May 8, 2023, his wife, Kouri Darden Richins was charged with his murder;
Murder_of_Eric_Richins
Atypical opioid drug
being its primary action. Unlike conventional opioids such as morphine and fentanyl, SR-17018 produces robust analgesic effects in rodents with very little
SR-17018
Slang term for opioid drug mixtures
potent mixtures of synthetic opioids, for example benzimidazole opioids or fentanyl analogues, which were often sold on the street misleadingly as "heroin"
Gray_death
fentanyl being imported into the United States, killing over 100 Americans every day. Over a two-year period, close to $800 million worth of fentanyl
Illegal_drug_trade_in_China
Chemical compound
compound, developed through modification of the fentanyl scaffold and with similar potency to fentanyl. It was designed as a mixed μ/δ opioid agonist but
Deekonda2016
Chemical compound
Benzylfentanyl (R-4129) is a fentanyl analog. It was temporarily placed in the US Schedule I by emergency scheduling in 1985 due to concerns about its
Benzylfentanyl
American rapper and singer (born 1984)
2024, Jelly Roll testified before the U.S. Congress in support of anti-fentanyl legislation. Explaining his perspective as a former distributor of illegal
Jelly_Roll_(singer)
Former American pharmaceutical manufacturer
fentanyl. Fentanyl is an extremely fast-acting and powerful opioid used to relieve breakthrough pain in cancer patients, and prescription of fentanyl
Insys_Therapeutics
American musician and songwriter (1958–2016)
overdosing on counterfeit hydrocodone/paracetamol pills which were laced with fentanyl. Prince's awards include the Grammy President's Merit Award, the American
Prince_(musician)
Opioid analgesic drug
is an analogue of fentanyl and was developed in the early 1990s. Brifentanil is most similar to highly potent, short-acting fentanyl analogues such as
Brifentanil
Topics referred to by the same term
may refer to: 4-anilino-N-phenethylpiperidine – a direct precursor to fentanyl All Nigeria Peoples Party Armenian Nuclear Power Plant The Army Nuclear
ANPP
Chemical compound
analogue of fentanyl where the piperidine ring has been cleaved to form an open-chain structure. It is around 40× less potent than fentanyl itself but
Secofentanyl
American actor (born 1943)
cause of death was determined as a combined drug intoxication involving fentanyl and cocaine. In February 1998, De Niro was held for questioning by French
Robert_De_Niro
3-Quinuclidinyl benzilate, the oripavine-derived Bentley-series opioid etorphine, fentanyl, 3-methylfentanil, another synthetic opioid analogous or derivative to
Moscow hostage crisis chemical agent
Moscow_hostage_crisis_chemical_agent
Chemical compound
opioids discovered, with an analgesic strength 20 times stronger than fentanyl. Starting in 2023, it has become an increasingly widespread drug of abuse
N-Desethylisotonitazene
American actor (1966–2021)
death in 2021 at age 54, after using heroin laced with a lethal amount of fentanyl. Four men were charged in the aftermath of his death with various crimes
Michael_K._Williams
Synthetic opioid analgesic precursor
opioid analgesic drug precursor to 4-fluorofentanyl. It is an analog of fentanyl. 3-Methylbutyrfentanyl 4-Fluorobutyrfentanyl 4-Fluorofentanyl α-Methylfentanyl
Despropionyl-p-fluorofentanyl
Opioid analgesic
Furanylfentanyl (Fu-F) is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug. It has an ED50 value of 0.02 mg/kg in
Furanylfentanyl
Opioid analgesic
relationships of the fentanyl family of drugs. R-30490 was found to be the most selective agonist for the μ-opioid receptor out of all the fentanyl analogues tested
R-30490
Opioid analgesic designer drug
of fentanyl first invented in 1973, and which has been sold as a designer drug. Side effects of fentanyl analogs are similar to those of fentanyl itself
Isofentanyl
American activist and advocate
rumor on TikTok suggested, falsely, that he was associated with smuggling fentanyl, also mistaking his name for Matthew. He soon posted a TikTok response
Gabriel_Ocasio-Cortez
American actor (1968–2023)
Angeles County Medical Examiner's autopsy report indicates Rich died from a fentanyl overdose. Carras, Christi (January 8, 2023). "Adam Rich, former child star
Adam_Rich
Chemical compound
sufficiently structurally distinct to fall outside the formal definition of a "fentanyl analogue" in jurisdictions such as the US and New Zealand which have Markush
Brorphine
like fentanyl, are contributing significantly to the alarming increase in overdose deaths. A considerable amount of illicitly produced fentanyl originates
Illegal drug trade in the United States
Illegal_drug_trade_in_the_United_States
Darknet news website
DeepDotWeb received about $8.4 million in kickbacks from purchases of fentanyl, firearms, hacking tools, and other contraband on Darknet marketplaces
DeepDotWeb
Chemical compound
an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug. As with other fentanyl analogues, parafluorofuranylfentanyl has
Parafluorofuranylfentanyl
American documentary film
abuse of drugs. Part two of the documentary follows the mass marketing of Fentanyl. While the opioid crisis was killing over 40 people per day, Insys Therapeutics
The Crime of the Century (2021 film)
The_Crime_of_the_Century_(2021_film)
Deaths due to abuse of opioid drugs
trade names OxyContin and Percocet), hydrocodone (Vicodin, Norco), and fentanyl (Abstral, Actiq, Duragesic, Fentora), which is a very strong painkiller
Opioid_epidemic
Chemical compound
slightly more potent than fentanyl. Side effects of benzimidazole derived opioids are likely to be similar to those of fentanyl, which include itching,
Isotonitazene
Hospital in Oregon, United States
2023, one of the hospital's nurses was accused of switching patients' fentanyl IVs with water in order to divert the supply to herself. This is believed
Rogue_Regional_Medical_Center
Opioid analgesic designer drug
that is an analog of fentanyl which has been sold as a designer drug. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include
2,2'-Difluorofentanyl
American actress (born 1967)
Leandro had died aged 19. It was later revealed to be due to accidental fentanyl poisoning. Living the De Niro Dream Archived October 23, 2013, at the Wayback
Drena_De_Niro
Opioid analgesic
that is an analog of fentanyl and has been sold as a designer drug. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include
Benzodioxolefentanyl
American politician and attorney (born 1951)
flow of fentanyl over the border. Kennedy introduced a bill to classify drug cartels as terrorist organizations because they traffic fentanyl, a drug
John Kennedy (Louisiana politician)
John_Kennedy_(Louisiana_politician)
2023 studio album by JPEGMafia and Danny Brown
the Hoes" samples a live performance of "Untitled" by Dirty Beaches. "Fentanyl Tester" samples "Milkshake" by Kelis. "Burfict!" interpolates "Procession
Scaring_the_Hoes
Russian invasion of Ukraine, support for Iran, transnational repression, and fentanyl production. Economic sanctions and export controls against China by the
United States sanctions against China
United_States_sanctions_against_China
American rapper (1989–2024)
from an accidental drug overdose after taking multiple drugs, including fentanyl, alprazolam, codeine, and promethazine in 2024. Dequantes Devontay Lamar
Rich_Homie_Quan
Ongoing economic conflict
to secure their borders with the U.S. against illegal immigration and fentanyl smuggling, and promote domestic manufacturing in the United States. Trudeau
2025–2026 Canada–United States trade war
2025–2026_Canada–United_States_trade_war
Country in Southeast Asia
Archived from the original on 26 April 2023. Retrieved 18 April 2023. "Huge fentanyl haul seized in Asia's biggest-ever drugs bust". Reuters. 18 May 2020. Archived
Myanmar
functional analogs are morphine, heroin and fentanyl, which have the same mechanism of action, but fentanyl is structurally quite different from the other
Functional_analog_(chemistry)
travel, tourism, insurance
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