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Chronic multi-symptomatic pain disorder
Fibromyalgia (FM) is a long-term condition characterised by widespread chronic pain. Other symptoms can include fatigue, trouble thinking or remembering
Fibromyalgia
Muscle relaxant medication
in topical creams.[citation needed] A 2004 review found benefit for fibromyalgia symptoms, with a reported number needed to treat of 4.8 (meaning that
Cyclobenzaprine
SNRI medication
disorder, generalized anxiety disorder, obsessive–compulsive disorder, fibromyalgia, neuropathic pain, and other types of chronic pain. It is taken by mouth
Duloxetine
2007 film
Living with Fibromyalgia: A Journey of Hope and Understanding is a 2007 documentary film by Stephen Eyer and Daneen Akers from Trillusion Media, Inc. The
Living_with_Fibromyalgia
Inflammation of the upper rib joints
further investigation for other, more serious causes of chest pain. Fibromyalgia may increase the pain effects of costochondritis. The exact etiology
Costochondritis
Investigational fibromyalgia drugs
investigational fibromyalgia drugs, or drugs that are currently under development for clinical use in the treatment of fibromyalgia but are not yet approved
List of investigational fibromyalgia drugs
List_of_investigational_fibromyalgia_drugs
US nonprofit organization
Fibromyalgia Association (NFA) is a nonprofit organization whose purpose is to help improve the quality of life for people living with fibromyalgia (FM)
National Fibromyalgia Association
National_Fibromyalgia_Association
Steroid medication
small study found that prednisone was ineffective in the treatment of fibromyalgia and that there was actually a trend towards deterioration. "Product monograph
Prednisone
SNRI medication
treatment of fibromyalgia, major depressive disorder, and neuropathic pain. In the US, it is solely approved for the treatment of fibromyalgia, even though
Milnacipran
Pseudoscientific needling treatment
pain and fibromyalgia. The evidence for its efficacy in shoulder pain is low quality and includes only two studies. Its efficacy for fibromyalgia does not
Acupuncture
Off-label, experimental use of the drug
studied for the treatment of multiple chronic pain conditions, including fibromyalgia, multiple sclerosis, Crohn's disease, long COVID, and complex regional
Low-dose_naltrexone
American actress (born 1974)
Langer raises awareness and money for the research and treatment of fibromyalgia, from which she herself suffers. Perry, Simon (November 21, 2017). "'My
A._J._Langer
Symptom
in some chronic pain conditions, with the archetypal condition being fibromyalgia. Exercise, psychotherapy, and medical therapies are commonly prescribed
Nociplastic_pain
Drug whose use induces sleep
treat non-restorative sleep and associated symptoms in conditions like fibromyalgia as well. This group of drugs is related to sedatives. Whereas the term
Hypnotic
Painful sensations in muscle tissue
caused by metabolic myopathy, some nutritional deficiencies, ME/CFS, fibromyalgia, and amplified musculoskeletal pain syndrome. The most common causes
Myalgia
Dietary recommendation to help ease gastrointestinal issues
including bloating and flatulence. It also seems to be beneficial in fibromyalgia. If the problem lies with indigestible fiber instead, the patient may
Low-FODMAP_diet
Worsening of symptoms with activity
infection-associated chronic conditions (IACCs) such as long COVID and fibromyalgia. PEM is often severe enough to be disabling, and is triggered by ordinary
Post-exertional_malaise
Nervous system disease affecting nerves beyond the brain and spinal cord
2014). "Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia". The Cochrane Database of Systematic Reviews. 2015 (1) CD007115. doi:10
Peripheral_neuropathy
Medical condition
syndrome (MPS) is commonly confused with fibromyalgia (FM) as their presentation is similar. However, fibromyalgia is typically associated with fatigue,
Myofascial_pain_syndrome
Medical symptom
has been especially associated with fibromyalgia and ME/CFS, with approximately 65 to 95% of people with fibromyalgia and 85 to 95% of people with ME/CFS
Non-restorative_sleep
Unusual discomfort when in a cool environment
anemia, low body weight, iron deficiency, vitamin B12 deficiency, fevers, fibromyalgia or vasoconstriction. There may also be differences in people in the expression
Cold_sensitivity
Anticonvulsant medication
anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, generalized anxiety disorder
Pregabalin
Impairment in the clarity of consciousness
implicated in the expression of brain fog symptoms. Many people with fibromyalgia experience cognitive problems (often called "fibrofog"), which may involve
Clouding_of_consciousness
Advocates presenting a petition to the Welsh Parliament requesting specialist care for people with ME/CFS and fibromyalgia
Controversies related to ME/CFS
Controversies_related_to_ME/CFS
Any disease or malfunction of the autonomic nervous system
nervous system (SNS), predominant dysautonomia is common along with fibromyalgia, chronic fatigue syndrome, irritable bowel syndrome, and interstitial
Dysautonomia
Tricyclic antidepressant
disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. Due to the frequency and prominence
Amitriptyline
Awareness day for various medical conditions
raise awareness of myalgic encephalomyelitis/chronic fatigue syndrome, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and other chronic immunological
International May 12th Awareness Day
International_May_12th_Awareness_Day
Medical condition
symptoms that people with NCGS may develop, such as neurological disorders, fibromyalgia, psychological disturbances, and dermatitis. For these reasons, NCGS
Non-celiac_gluten_sensitivity
Chemical compound
Esreboxetine was developed by Pfizer for the treatment of neuropathic pain and fibromyalgia. It failed to show significant benefit over currently available medications
Esreboxetine
Short-chain carbohydrates poorly absorbed in the small intestine
restricting FODMAPs, might help to improve digestive symptoms in adults with fibromyalgia, irritable bowel syndrome (IBS) and other functional gastrointestinal
FODMAP
Unapproved treatment for fibromyalgia
Guaifenesin protocol is a treatment to reverse fibromyalgia suggested since the 1990s by R. Paul St. Amand, M.D. of UCLA. The protocol involves three parts:
Guaifenesin_protocol
Class of antidepressant medication
depressive disorder (MDD), anxiety disorders, chronic neuropathic pain, fibromyalgia, and menopausal symptoms. Off-label uses include treatments for attention
Serotonin–norepinephrine reuptake inhibitor
Serotonin–norepinephrine_reuptake_inhibitor
Chronic medical condition
feature of ME/CFS, but is more closely associated with fibromyalgia. Modern definitions of fibromyalgia not only include widespread pain but also fatigue,
Myalgic encephalomyelitis/chronic fatigue syndrome
Myalgic_encephalomyelitis/chronic_fatigue_syndrome
Process of transplantation of fecal bacteria from a healthy individual into a recipient
pain intensity and improve fatigue and quality of life in patients with fibromyalgia. A 2023 review found that fecal microbiota transplantation improved symptoms
Fecal_microbiota_transplant
Anticonvulsant and analgesic medication
cocaine addiction, dementia, depression, diabetic peripheral neuropathy, fibromyalgia, headache, hiccups, Huntington's disease, mania, migraine, obsessive-compulsive
Lacosamide
Excessive focus on distressing physical symptoms
disorder is frequently associated with functional pain syndromes, such as fibromyalgia and irritable bowel syndrome (IBS). Somatic symptom disorder typically
Somatic_symptom_disorder
Chemical compound
Effective: for post-herpetic neuralgia (trial: NEUCOURSE) Ineffective: for fibromyalgia (trial: ALDAY) Effective: for diabetic peripheral neuropathic pain (trial:
Mirogabalin
Belief that symptoms are caused by an unproven infection
to chronic Lyme are in many cases likely due to fibromyalgia or myalgic encephalomyelitis. Fibromyalgia can be triggered by an infection, and antibiotics
Chronic_Lyme_disease
Form of neurostimulation
insomnia. CES has been suggested as a possible treatment for headaches, fibromyalgia, smoking cessation, and opiate withdrawal, but there is little evidence
Cranial electrotherapy stimulation
Cranial_electrotherapy_stimulation
Nervous system condition
examined hypervigilance in relation to chronic pain conditions, namely fibromyalgia and rheumatoid arthritis. People suffering from hypervigilance may become
Hypervigilance
Chinese system of coordinated posture and movement, breathing, and meditation
efficacy in alleviating fibromyalgia symptoms including pain, sleep quality, fatigue, anxiety, depression, and fibromyalgia impact, as per a pilot randomized
Qigong
British novelist
struggled with undiagnosed health issues, until she was diagnosed with fibromyalgia. She also has Ehlers–Danlos syndrome. Hibbert's issues with doctors inspired
Talia_Hibbert
American anesthesiologist, pain medicine physician, and clinical researcher
and repetitive transcranial magnetic stimulation for the treatment of fibromyalgia, chronic pain, and related conditions, with an emphasis on reducing reliance
Anna_Woodbury
Commercial pharmaceutical company
management of fibromyalgia. On August 15, 2025, the U.S. Food and Drug Administration approved TNX-102 SL as TONMYA™ for the management of fibromyalgia, making
Tonix_Pharmaceuticals
SSRI antidepressant
well-tolerated and improve the overall symptomatology in patients with fibromyalgia", but is less robust in helping with the pain involved. Off-label paroxetine
Paroxetine
Interdisciplinary approach for easing pain
include chronic low back pain, osteoarthritis of the hip and knee, and fibromyalgia. Exercise alone or with other rehabilitation disciplines (including psychotherapeutic
Pain_management
Pharmaceutical compound
cannabinoid receptor modulator which is under development for the treatment of fibromyalgia, generalized anxiety disorder, interstitial cystitis, major depressive
ONO-1110
Hyperirritable spots in skeletal muscle
trigger points in the diagnosis of fibromyalgia is thin. More recently, an association has been made between fibromyalgia tender points and active trigger
Myofascial_trigger_point
Method of treating diseases by bathing
recommended for various illnesses, including arthritis, skin conditions and fibromyalgia. Balneotherapy should be discussed in advance with a physician before
Balneotherapy
Part of the eye
early detection and diagnosis of glaucoma. One small study found that fibromyalgia patients had decreased RNFL thickness but another found no difference
Retinal_nerve_fiber_layer
Medical condition
possibly the immune system, rather than from peripheral tissue damage. Fibromyalgia, chronic fatigue syndrome (now called ME/CFS) and irritable bowel syndrome
Functional_somatic_syndrome
Medical condition of the bladder and pelvic floor
life. Some of those affected also have irritable bowel syndrome and fibromyalgia. The cause of interstitial cystitis is unknown. While it can, it does
Interstitial_cystitis
American singer, songwriter and actress (born 1986)
was later revealed to be the effect of a long-term condition called fibromyalgia. In February 2018, it prompted Gaga to cancel the last ten shows of the
Lady_Gaga
Heritable connective tissue disorder
Chavrimootoo, S.; Ramakrishnan, S. (1 June 2018). "AB1411-HPR Hypermobility and fibromyalgia: coexistence or mistaken identity?". Annals of the Rheumatic Diseases
Hypermobility spectrum disorder
Hypermobility_spectrum_disorder
Disease of the bony spine that results in narrowing of the spinal canal
diagnosis Cauda equina syndrome, osteomylitis, peripheral vascular disease, fibromyalgia Treatment Medications, exercises, bracing, surgery. Medication NSAIDs
Spinal_stenosis
1990–1991 conflict in the Middle East
Gulf War illness (GWI). Common symptoms reported are chronic fatigue, fibromyalgia, and gastrointestinal disorder. There has been widespread speculation
Gulf_War
American musician
Danzig. In December 2008, Hardy revealed that she had been diagnosed with fibromyalgia. She was prescribed the opioid drug Norco to treat her pain, which resulted
Annie_Hardy
High amplitude low frequency brain wave
at a rate of 56% (compared to 14% in healthy controls). Patients with fibromyalgia often report unrefreshing sleep. A study conducted in 1975 by Moldovsky
Delta_wave
Medical theory
of endocannabinoids is the underlying pathophysiology of migraines, fibromyalgia, and irritable bowel syndrome. The deficiency may sometimes start in
Clinical endocannabinoid deficiency syndrome
Clinical_endocannabinoid_deficiency_syndrome
American physician
has done extensive research in musculoskeletal medicine focusing on fibromyalgia and the structure of the musculoskeletal system and how it affects function
Tyler_Cymet
American internet personality (born 1988)
bisexual. On May 3, 2024, Gilardi revealed that he had been diagnosed with fibromyalgia, which had affected the scope of his animated work. On August 1, 2026
Max_Gilardi
State of desire for sleep, for unusually long periods
tumor Chronic pains Concussion – a mild traumatic brain injury Diabetes Fibromyalgia Head injury Hypercalcemia – too much calcium in the blood Hypermagnesemia
Somnolence
Class of medication used to treat depression and other conditions
affects pain, health-related quality of life, depression, and sleep in fibromyalgia syndrome. Tricyclics appear to be the most effective class, with moderate
Antidepressant
American singer (1945–2017)
concerts until 2002, before retiring from live performances due to advanced fibromyalgia. Hamlin's "Angel Baby" was covered by several artists, including Linda
Rosie_Hamlin
Techniques to train attention and awareness
pain, functional status, and self-efficacy in persons diagnosed with fibromyalgia. Journal of Alternative and Complementary Medicine, Vol. 12, No. 1, 2006
Meditation
v t e Neuropathic pain and fibromyalgia pharmacotherapies Monoaminergics SNRIsTooltip Serotonin–norepinephrine reuptake inhibitor (e.g., duloxetine, milnacipran)
List of investigational analgesics
List_of_investigational_analgesics
Norepinephrine reuptake inhibitor
the treatment of attention deficit hyperactivity disorder (ADHD) and fibromyalgia, but development for these uses was discontinued. List of investigational
Ampreloxetine
Film claiming root canals cause disease
root canals or infected teeth can lead to migraines, diabetes, lupus, fibromyalgia and heart disease. The film makes specific false claims of "97% of patients
Root_Cause_(film)
English media figure (born 1972)
her previous appearance, she had been diagnosed with fibromyalgia. "Celebrities face fibromyalgia (5 of 8)". CNN. 1 August 2017. Retrieved 28 September
Jo_Guest
State of overwhelm caused by an excess of sensory input
tics in an environment of overwhelming sensory stimuli. Fibromyalgia People with fibromyalgia are hypersensitive to intense stimuli such as bright lights
Sensory_overload
Pharmaceutical compound
explored. There was also interest in JZP-386 for the potential treatment of fibromyalgia. List of investigational narcolepsy and hypersomnia drugs Valiloxybate
JZP-386
Chemical compound
syndrome, major depressive disorder, bipolar disorder, neuropathic pain, fibromyalgia, and obesity. Regulatory filing was planned for 2007, but development
Radafaxine
Scottish television radio presenter
Island Discs "for a number of months" to receive treatment for a form of fibromyalgia, and that Lauren Laverne would deputise during this period. In July 2019
Kirsty_Young
Thiamine analogue
v t e Neuropathic pain and fibromyalgia pharmacotherapies Monoaminergics SNRIsTooltip Serotonin–norepinephrine reuptake inhibitor (e.g., duloxetine, milnacipran)
Benfotiamine
Proteins that bind lipids to transport them in body fluids
diseases and dysfunction. ApoC1 level increases in neuropathic pain and fibromyalgia patients which suggest it plays an important role in occurrence of these
Apolipoprotein
Blood clot
Postural Orthostatic Tachycardia Syndrome (POTS), atrial fibrillation, and fibromyalgia. Fibrinaloid microclots are easily measured using techniques such as
Thrombus
American physician
practice with five centers that offer treatment for conditions including fibromyalgia, adrenal fatigue (a non-existent condition), complex endocrine dysfunction
Kent_Holtorf
Chemical compound
clinical data show potential benefits in the management of arthritis and fibromyalgia.[unreliable medical source?] Cetyl myristoleate was isolated for the
Cetyl_myristoleate
Topics referred to by the same term
(see Annunciator panel) Chinese Wikipedia Chronic Widespread Pain (see Fibromyalgia#Genetics) Coalition of Women for a Just Peace Coalworker's pneumoconiosis
CWP
Condition characterized by amplified and chronic pain
This type of AMPS includes full-body pain. It is also known as juvenile fibromyalgia.[citation needed] This type of AMPS refers to amplified pain that varies
Amplified musculoskeletal pain syndrome
Amplified_musculoskeletal_pain_syndrome
Type of sexual assault involving sexual intercourse without consent
pelvic inflammatory disease, sexual dysfunction, premenstrual distress, fibromyalgia, vaginal discharge, vaginal itching, burning during urination, and generalized
Rape
Uncomfortable skin sensation
causes is known as uremic pruritus mast cell activation syndrome (MCAS). fibromyalgia Drugs (such as opioids) that activate histamine (H1) receptors or trigger
Itch
Functional gastrointestinal disorder
gastroesophageal reflux, symptoms relating to the genitourinary system, fibromyalgia, headache, backache, and psychiatric symptoms such as depression, sleep
Irritable_bowel_syndrome
Antidepressant medication
and migraines in children. Trazodone may be useful in the treatment of fibromyalgia as well as diabetic neuropathy. It may also be useful in the treatment
Trazodone
American television dancer, choreographer, actress, and singer (born 1968)
with Lupus. She also has chronic fatigue syndrome, chronic pain, and fibromyalgia. In 2019 while on The Talk, Inaba also opened up about struggling with
Carrie_Ann_Inaba
Pharmaceutical compound
under development for the treatment of cancer pain, neuropathic pain, fibromyalgia, and Tourette's syndrome but was never marketed. It was formulated as
ZYN-001
treatment for a wide variety of orthopedic conditions such as headaches, fibromyalgia, sciatica, tendinitis, chronic neck pain, and post-surgical conditions
Strain_and_counterstrain
Fraudulent alternative medical treatment
medical treatment which is claimed to cure cancer, multiple sclerosis, fibromyalgia and other diseases. There is no scientific evidence that 714-X is effective
714-X
Species of bacterium
on a possible link to it being a cofactor in HIV infection as well as fibromyalgia, Gulf War syndrome and Chronic fatigue syndrome, however the belief that
Mycoplasma_fermentans
Redness of the face due to physiological conditions
Latinized Greek word for "redness" and the Latin "of embarrassment") fever fibromyalgia histamines homocystinuria (flushing across the cheeks) Horner's syndrome
Flushing_(physiology)
Enzyme
intolerance, and for the relief of other conditions, such as migraine or fibromyalgia. However, the results are inconclusive because studies to date have involved
Diamine_oxidase
Synthetic cannabinoid
clinical trials and case studies have demonstrated modest effectiveness in fibromyalgia and multiple sclerosis. Nabilone is used to treat nausea and vomiting
Nabilone
American actress (1968–2018)
and left her almost entirely house bound. She also had celiac disease, fibromyalgia, and depression at the time of her death, and had regular seizures. English
Vanessa_Marquez
Serotonin antagonist/antiemetic
although it has been used experimentally as an analgesic in cases of fibromyalgia. It was patented in 1982 and approved for medical use in 1992. Tropisetron
Tropisetron
Medical conditions
number or rare autoimmune conditions, secondary autoimmunities, such as fibromyalgia that are more frequent in GSE than in the normal population. Gulliane-Barre
Gluten-sensitive enteropathy–associated conditions
Gluten-sensitive_enteropathy–associated_conditions
American author and spokesperson (1942–2019)
children. After being diagnosed with Fibromyalgia, Winfield she became a spokeswoman for the National Fibromyalgia Association. Winfield died on April
Frances_Winfield
disorder counts is up for debate. An example of a wastebasket diagnosis is fibromyalgia diagnosed via muscle pain of unclear source. Evidence-based medicine
Unsolved_problems_in_medicine
American nonprofit organization
illnesses myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), fibromyalgia, post-treatment Lyme disease syndrome, and long COVID. The OMF was founded
Open_Medicine_Foundation
Neuroscientist
a "breakthrough on chronic pain." His study of neuroinflammation in fibromyalgia, conducted in collaboration with Karolinska Institutet, was named one
Marco_Loggia
Type of behavior therapy
appeared to give promising results. One study found it to be effective with fibromyalgia-related pain anxiety. In another, researchers observed a notable improvement
Behavioral_activation
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