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GALECTIN 1

  • Galectin
  • Protein family binding to β-galactoside sugars

    Galectins are a class of proteins that bind specifically to β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which

    Galectin

    Galectin

    Galectin

  • Galectin-1
  • Protein-coding gene in the species Homo sapiens

    Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. LGALS1 contains four exons. The galectin-1 protein is 135 amino acids in length and

    Galectin-1

    Galectin-1

    Galectin-1

  • Galectin-3
  • Protein-coding gene in the species Homo sapiens

    Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have

    Galectin-3

    Galectin-3

    Galectin-3

  • Neural stem cell
  • Precursor cells of neurons and glia during embryonic development

    used to infect human NSCs (hNSCs) with Galectin-1 which were later transplanted into the damaged tissue. The hGal-1-hNSCs induced better and faster brain

    Neural stem cell

    Neural_stem_cell

  • Galectin-2
  • Protein-coding gene in the species Homo sapiens

    Galectin-2 is a protein that in humans is encoded by the LGALS2 gene. The protein encoded by this gene is a soluble beta-galactoside binding lectin. The

    Galectin-2

    Galectin-2

    Galectin-2

  • Triple-negative breast cancer
  • Type of breast cancer lacking certain gene expressions

    glycolysis in these tumors is probably related to their aggressive biology. Galectin-1 in TNBC is a beta-galactosidase-binding protein that shields cancer cells

    Triple-negative breast cancer

    Triple-negative_breast_cancer

  • Galectin-4
  • Protein-coding gene in the species Homo sapiens

    Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating

    Galectin-4

    Galectin-4

    Galectin-4

  • LGALS3BP
  • Protein-coding gene in the species Homo sapiens

    Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene. The galectins are a family of beta-galactoside-binding proteins

    LGALS3BP

    LGALS3BP

    LGALS3BP

  • Endothelial cell anergy
  • Defense mechanism of tumors against immunity

    proteins that can deliver death signals in leukocytes (Fas ligand and galectin-1). The formation of a leukocyte infiltrate at places of inflammation is

    Endothelial cell anergy

    Endothelial cell anergy

    Endothelial_cell_anergy

  • List of MeSH codes (D12.776)
  • dehydrogenase MeSH D12.776.377.715.085.050 – alpha 1-antichymotrypsin MeSH D12.776.377.715.085.085 – alpha 1-antitrypsin MeSH D12.776.377.715.085.100 – alpha-macroglobulins

    List of MeSH codes (D12.776)

    List_of_MeSH_codes_(D12.776)

  • Tolerogenic dendritic cell
  • such as PD-L1 and PD-L2, heme oxygenase 1, HLA-G, CD95L, TNF-related apoptosis inducing ligands, galectin-1 and DC-SIGN and production of immunosuppressive

    Tolerogenic dendritic cell

    Tolerogenic_dendritic_cell

  • Gem-associated protein 4
  • Protein-coding gene in the species Homo sapiens

    Grabski S, Wang JL, Patterson RJ (September 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic

    Gem-associated protein 4

    Gem-associated protein 4

    Gem-associated_protein_4

  • Margaret Shipp
  • American oncologist

    targeted drugs. Following this, Shipp's research team found that serum galectin-1 levels were "significantly associated with tumor burden and additional

    Margaret Shipp

    Margaret_Shipp

  • Galectin-9
  • Protein-coding gene in the species Homo sapiens

    Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9

    Galectin-9

    Galectin-9

    Galectin-9

  • Belapectin
  • Pharmaceutical compound

    Belapectin (also known as GR-MD-02) is a galectin-3 inhibitor developed by Galectin Therapeutics for the treatment of non-alcoholic steatohepatitis. In

    Belapectin

    Belapectin

  • Gabriel A. Rabinovich
  • Argentine biochemist

    how such tumors can be regressed. He also looked at the properties of galectins, and how they show potential for disease. Rabinovich was born in Córdoba

    Gabriel A. Rabinovich

    Gabriel A. Rabinovich

    Gabriel_A._Rabinovich

  • Bethan Psaila
  • British haematologist

    proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis. Science translational medicine, 16(768), eadj7552. Olijnik, A. A

    Bethan Psaila

    Bethan_Psaila

  • Fibroblast growth factor 23
  • Protein found in humans

    Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States

    Fibroblast growth factor 23

    Fibroblast growth factor 23

    Fibroblast_growth_factor_23

  • CD7
  • Mammalian protein found in humans

    membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". Journal of Immunology. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7

    CD7

    CD7

    CD7

  • Galectin-8
  • Protein found in humans

    Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene. This gene encodes a member of the galectin family. Galectins

    Galectin-8

    Galectin-8

    Galectin-8

  • LGALS13
  • Protein-coding gene in the species Homo sapiens

    Placental protein 13 (PP13, also known as galectin-13) is a protein that in humans is encoded by the LGALS13 gene. It is composed of two identical subunits

    LGALS13

    LGALS13

    LGALS13

  • CLC (gene)
  • Protein-coding gene in humans

    Galectin-10 is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional

    CLC (gene)

    CLC (gene)

    CLC_(gene)

  • VPREB1
  • Protein-coding gene in the species Homo sapiens

    PMID 11994467. Gauthier L, Rossi B, Roux F, Termine E, Schiff C (October 2002). "Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in

    VPREB1

    VPREB1

    VPREB1

  • Jun dimerization protein 2
  • Protein-coding gene in the species Homo sapiens

    Cox AD, Kloog Y (February 2013). "Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis". Oncotarget. 4 (2): 256–268

    Jun dimerization protein 2

    Jun dimerization protein 2

    Jun_dimerization_protein_2

  • ROMK
  • Potassium channel

    Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States

    ROMK

    ROMK

    ROMK

  • Diana L. Farmer
  • American pediatric surgeon

    spina bifida. In 2019, Farmer and Aijun Wang identified exosomes and galectin 1 as key to protecting neurons and ultimately reducing the lower-limb paralysis

    Diana L. Farmer

    Diana_L._Farmer

  • Galectin-7
  • Protein-coding gene in the species Homo sapiens

    Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding lectins involved in modulating

    Galectin-7

    Galectin-7

    Galectin-7

  • CD43
  • Mammalian protein found in humans

    membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". J. Immunol. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7.3801. PMID 10490978

    CD43

    CD43

    CD43

  • HSPC159
  • Protein-coding gene in the species Homo sapiens

    Galectin-related protein, also known as HSPC159, is a human gene. GRCh38: Ensembl release 89: ENSG00000119862 – Ensembl, May 2017 GRCm38: Ensembl release

    HSPC159

    HSPC159

    HSPC159

  • Endogenous regeneration
  • (HGF), Notch-1, sonic hedgehog (SHH), noggin, ciliary neurotrophic factor (CNTF), and a soluble carbohydrate-binding protein, Galectin-1, are reported

    Endogenous regeneration

    Endogenous_regeneration

  • Charcot–Leyden crystals
  • Microscopic crystals composed of eosinophil protein galectin-10

    Charcot–Leyden crystals are microscopic crystals composed of eosinophil protein galectin-10 found in people who have allergic diseases such as asthma or parasitic

    Charcot–Leyden crystals

    Charcot–Leyden crystals

    Charcot–Leyden_crystals

  • Chemical imaging
  • Simultaneous measurement of spectra and pictures

    Molecular and Cellular Biology (2008) 4377–4385. Belanis L, et al., Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters

    Chemical imaging

    Chemical_imaging

  • Selvigaltin
  • Chemical compound

    Selvigaltin (GB1211) is the first small-molecule, orally delivered galectin-3 inhibitor to be discovered. It is developed by Galecto Biotech, which is

    Selvigaltin

    Selvigaltin

    Selvigaltin

  • Ben Carson
  • American neurosurgeon and government official (born 1951)

    became official on July 1, 2013. In 2021, Carson joined Galectin Therapeutics to assist with development of the company's galectin-3 inhibitor, belapectin

    Ben Carson

    Ben Carson

    Ben_Carson

  • Integrin beta 1
  • Mammalian protein found in Homo sapiens

    Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (Jul 2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". Journal

    Integrin beta 1

    Integrin beta 1

    Integrin_beta_1

  • CCL17
  • Mammalian protein found in humans

    evaluation of treatment response in classical Hodgkin lymphoma: comparison of sGalectin-1, sCD163 and sCD30 with TARC". British Journal of Haematology. 175 (5):

    CCL17

    CCL17

    CCL17

  • HAVCR2
  • Protein-coding gene in the species Homo sapiens

    In addition to galectin-9, several ligands have been identified, such as phosphatidylserine (PtdSer), High Mobility Group Protein 1 (HMGB1) and Carcinoembryonic

    HAVCR2

    HAVCR2

    HAVCR2

  • Gem-associated protein 2
  • Protein-coding gene in the species Homo sapiens

    1016/S1097-2765(01)00244-1. PMID 11389857. Park JW, Voss PG, Grabski S, Wang JL, Patterson RJ (September 2001). "Association of galectin-1 and galectin-3 with Gemin4

    Gem-associated protein 2

    Gem-associated protein 2

    Gem-associated_protein_2

  • MTORC1
  • Protein complex

    Claude-Taupin A, et al. (April 2018). "Galectins Control mTOR in Response to Endomembrane Damage". Molecular Cell. 70 (1): 120–135.e8. doi:10.1016/j.molcel

    MTORC1

    MTORC1

    MTORC1

  • NEK8
  • Protein-coding gene in the species Homo sapiens

    Yunis R, Mak SK, et al. (2005). "Nek8 mutation causes overexpression of galectin-1, sorcin, and vimentin and accumulation of the major urinary protein in

    NEK8

    NEK8

    NEK8

  • Thymic nurse cell
  • negatively selected to undergo apoptosis. The molecules like gal-3 (Galectin-3) and gal-1(Galectin-1), on the other hand, produce antagonistic effects. They inhibit

    Thymic nurse cell

    Thymic_nurse_cell

  • TRPV5
  • Protein-coding gene in the species Homo sapiens

    Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States

    TRPV5

    TRPV5

    TRPV5

  • Small nuclear ribonucleoprotein D1
  • Protein-coding gene in the species Homo sapiens

    1016/S1097-2765(01)00244-1. PMID 11389857. Park JW, Voss PG, Grabski S, Wang JL, Patterson RJ (Sep 2001). "Association of galectin-1 and galectin-3 with Gemin4 in

    Small nuclear ribonucleoprotein D1

    Small nuclear ribonucleoprotein D1

    Small_nuclear_ribonucleoprotein_D1

  • Richard and Elizabeth Uihlein
  • American business people

    spa, and gift shops. Richard Uihlein is the chairman of the board for Galectin Therapeutics, a publicly traded biotech company focusing on treatments

    Richard and Elizabeth Uihlein

    Richard_and_Elizabeth_Uihlein

  • Pancreatic stellate cell
  • matri-cellular proteins. The up regulation of matri-cellular proteins such as galectin-1, and tenascin-C is present in the stromal tissues of pancreatic cancer

    Pancreatic stellate cell

    Pancreatic_stellate_cell

  • Anatole Klyosov
  • Russian scientist (born 1946)

    Atlanta, GA. The company was renamed as Galectin Therapeutics in May 2011. The company was renamed as Galectin Therapeutics in May 2011. He then became

    Anatole Klyosov

    Anatole Klyosov

    Anatole_Klyosov

  • MTOR
  • Mammalian protein found in humans

    galectin, galectin-3, interacts with TRIM16 to guide selective autophagy of damaged lysosomes. TRIM16 gathers ULK1 and principal components (Beclin 1

    MTOR

    MTOR

    MTOR

  • Autophagy
  • Process of cells digesting parts of themselves

    involved in response to lysosomal damage, often directed by galectins such as galectin-3 and galectin-8. Repair of damaged DNA involves the recruitment of enzymes

    Autophagy

    Autophagy

    Autophagy

  • Catenin beta-1
  • Mammalian protein found in humans

    reducing β-catenin nuclear accumulation is via the inhibition of galectin-3. The galectin-3 inhibitor GR-MD-02 is currently undergoing clinical trials in

    Catenin beta-1

    Catenin beta-1

    Catenin_beta-1

  • Mesohyl
  • Gelatinous matrix within a sponge

    of the following main elements: collagen, fibronectin-like molecules, galectin, and a minor component, dermatopontin. These polypeptides form the extracellular

    Mesohyl

    Mesohyl

  • Stingray
  • Suborder of fishes

    confirmed to be within the venom are cystatins, peroxiredoxin and galectin. Galectin induces cell death in its victims and cystatins inhibit defense enzymes

    Stingray

    Stingray

    Stingray

  • Consortium for Functional Glycomics
  • Glycomics research initiative

    major classes of mammalian glycan-binding proteins (GBPs): C-type lectin, galectin, and SIGLEC immune receptors that bind carbohydrates: CD1, T cell receptor

    Consortium for Functional Glycomics

    Consortium_for_Functional_Glycomics

  • AMP-activated protein kinase
  • Class of enzymes

    "TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis". Developmental Cell. 39 (1): 13–27

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • RAGE (receptor)
  • Protein-coding gene in the species Homo sapiens

    that may contribute to the cell's response to oxidative stress. Galectin-3 (AGE-R3):Galectin-3 is a lectin that binds AGEs and facilitates their removal from

    RAGE (receptor)

    RAGE (receptor)

    RAGE_(receptor)

  • Myeloid-derived suppressor cell
  • Group of immune cells in the bone marrow

    evidence for inhibiting Galectin-3 as a therapeutic target to reduce MDSCs. In a Phase 1b clinical trial of GR-MD-02 developed by Galectin Therapeutics, investigators

    Myeloid-derived suppressor cell

    Myeloid-derived_suppressor_cell

  • Sunil Kumar Podder
  • Indian molecular biologist and biophysicist

    (September 2000). "Elucidation of the mechanism of interaction of sheep spleen galectin-1 with splenocytes and its role in cell–matrix adhesion". Journal of Molecular

    Sunil Kumar Podder

    Sunil_Kumar_Podder

  • HAVCR1
  • Protein-coding gene in the species Homo sapiens

    TB, Kuchroo VK (December 2005). "The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity". Nature Immunology. 6 (12): 1245–1252. doi:10

    HAVCR1

    HAVCR1

    HAVCR1

  • Concanavalin domain
  • Protein structural motif

    (May 1998). "X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution". The Journal of Biological Chemistry

    Concanavalin domain

    Concanavalin domain

    Concanavalin_domain

  • Argopecten irradians
  • Species of bivalve

    the first bivalve PGRP to be cloned. AiGal1 is a galectin discovered by Song et al. 2010, CfToll-1 is a toll-like receptor (TLR) shared with other bivalves

    Argopecten irradians

    Argopecten irradians

    Argopecten_irradians

  • List of statistical tests
  • Andrea; Carpi, Federico; Mechanick, Jeffrey I.; Bartolazzi, Armando (2010). "Galectin-3 detection on large-needle aspiration biopsy improves preoperative selection

    List of statistical tests

    List_of_statistical_tests

  • Pancreatic cancer
  • Type of endocrine gland cancer

    approach involves the use of immunotherapy, such as oncolytic viruses. Galectin-specific mechanisms of the tumor microenvironment are under study. Because

    Pancreatic cancer

    Pancreatic cancer

    Pancreatic_cancer

  • Ferroptosis
  • Type of programmed cell death

    This phenomenon is promoted by secretion of galectin-13 during ferroptosis. Mechanistically, galectin-13 binds to CD44, inhibiting CD44-mediated membrane

    Ferroptosis

    Ferroptosis

  • TB006
  • Monoclonal antibody

    TB006 is a humanized monoclonal antibody targeting galectin-3, which is suspected to be a factor in the formation of amyloid plaques. The drug is being

    TB006

    TB006

  • Chromosome 2
  • Human chromosome

    HSPC159: Galectin-related protein ID2-AS1: encoding protein Id2 antisense rna 1 (head to head) LCLAT1: encoding protein Lysocardiolipin acyltransferase 1 LEPQTL1:

    Chromosome 2

    Chromosome 2

    Chromosome_2

  • LAMP1
  • Protein-coding gene in humans

    and E-selectin and galectins, with the LAMPs serving as ligands for the cell-adhesion molecules. Cell membrane expression of LAMP-1 observed in the following

    LAMP1

    LAMP1

    LAMP1

  • Cnidocyte
  • Stinging cell used by cnidarians

    composed of polymerized NOWA (Nematocyst Outer Wall Antigen) proteins. Nemato Galectin, minicollagen Ncol-15 and chondroitin are novel proteins used to build

    Cnidocyte

    Cnidocyte

    Cnidocyte

  • Interleukin 6
  • Cytokine protein

    and Galectin-3. There is considerable functional overlap and interaction between Substance P (SP), the natural ligand for the neurokinin type 1 receptor

    Interleukin 6

    Interleukin 6

    Interleukin_6

  • Pleurotus pulmonarius
  • Species of mushroom

    of P. pulmonarius may slow the proliferation of cancer cells with high galectin-3 levels, while at the same time downregulate tumour cell adherence – which

    Pleurotus pulmonarius

    Pleurotus pulmonarius

    Pleurotus_pulmonarius

  • CEACAM1
  • Mammalian protein found in humans

    Karlsson A (November 1999). "Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils". Journal of Immunology. 163

    CEACAM1

    CEACAM1

    CEACAM1

  • Coronavirus spike protein
  • Glycoprotein spike on a viral capsid or viral envelope

    called CEACAM1. The NTD has a galectin-like protein fold, but binds sugar molecules somewhat differently than galectins. The observed binding of N-acetylneuraminic

    Coronavirus spike protein

    Coronavirus spike protein

    Coronavirus_spike_protein

  • Polyvalency (chemistry)
  • Property of chemical species that can form multiple bonds

    saccharides on the binding of domain-I of recombinant tandem-repeat-type galectin-4 from rat gastrointestinal tract (G4-N)". Biochimie. 86 (4–5): 317–326

    Polyvalency (chemistry)

    Polyvalency (chemistry)

    Polyvalency_(chemistry)

  • Signal peptide
  • Short peptide present at N-terminal of newly synthesized proteins

    peptides can also be secreted by unconventional mechanisms. E.g. Interleukin, Galectin. The process by which such secretory proteins gain access to the cell exterior

    Signal peptide

    Signal_peptide

  • Amyloid
  • Insoluble protein aggregate with a fibrillar morphology

    j)\\&+2k_{\rm {off}}f(t,j+1)-2k_{\rm {off}}f(t,j)\\&+k_{-}\sum _{i=j+1}^{\infty }f(t,i)-k_{-}(j-1)f(t,j)\\&+k_{1}m(t)^{n_{1}}\delta _{j,n_{1}}+k_{2}m(t)^{n_{2}}M(t)\delta

    Amyloid

    Amyloid

    Amyloid

  • Arylsulfatase B
  • Mammalian protein found in Homo sapiens

    in free galectin-3, which attaches more strongly to less sulfated chondroitin 4-sulfate. Galectin-3 then acts on transcription factors AP-1 to increase

    Arylsulfatase B

    Arylsulfatase B

    Arylsulfatase_B

  • Papillary thyroid cancer
  • Medical condition

    Rodriguez J, De Pompa R, Bartolazzi A, Rosai J (April 2005). "Galectin-3 and HBME-1 expression in well-differentiated thyroid tumors with follicular

    Papillary thyroid cancer

    Papillary thyroid cancer

    Papillary_thyroid_cancer

  • Antimicrobial peptides
  • Class of peptides that have antimicrobial activity

    Al-Dhabi NA, Arockiaraj J (June 2017). "Bactericidal activity of fish galectin 4 derived membrane-binding peptide tagged with oligotryptophan". Developmental

    Antimicrobial peptides

    Antimicrobial peptides

    Antimicrobial_peptides

  • Proteinopathy
  • Diseases caused by abnormal protein structure

    tauopathy, synucleinopathy, and the aggregation of superoxide dismutase-1 (SOD1), polyglutamine, and TAR DNA-binding protein-43 (TDP-43). In all of

    Proteinopathy

    Proteinopathy

    Proteinopathy

  • Vojo Deretic
  • American geneticist

    damage: GALTOR (galectin-8–mTOR) links endomembrane damage to autophagy, galectin-3 recruits ESCRTs for lysosome repair, and galectin-9 activates AMPK

    Vojo Deretic

    Vojo Deretic

    Vojo_Deretic

  • Multiomics
  • Biological analysis approach

    Berhane; Schwartz, Stanley A. (February 2025). "Omics analysis reveals galectin-3 to be a potential key regulator of allergic inflammation in hereditary

    Multiomics

    Multiomics

    Multiomics

  • Glycan–protein interaction
  • Class of biological intermolecular interactions

    Common oligomerization structures of lectins are shown below. For example, galectins are usually observed as dimers, while intelectins form trimers and pentraxins

    Glycan–protein interaction

    Glycan–protein interaction

    Glycan–protein_interaction

  • Human coronavirus OC43
  • Species of virus

    PMC 5457962. PMID 27578435. BCoV S1-NTD does not recognize galactose as galectins do. Instead, it recognizes 5-N-acetyl-9-O-acetylneuraminic acid (Neu5

    Human coronavirus OC43

    Human coronavirus OC43

    Human_coronavirus_OC43

  • Bimolecular fluorescence complementation
  • Technology used to validate protein interactions

    V., Inohara, H. & Raz, A. Importin-mediated nuclear translocation of galectin-3. J. Biol. Chem. 281, 39649-39659 (2006). Liu, H. et al. Mutual regulation

    Bimolecular fluorescence complementation

    Bimolecular fluorescence complementation

    Bimolecular_fluorescence_complementation

  • ST2 cardiac biomarker
  • Member of the interleukin 1 receptor family

    biomarkers such as BNP, NT-proBNP, highly sensitive troponin, GDF-15, and galectin-3. One study indicated that discrimination is independent of age, body

    ST2 cardiac biomarker

    ST2_cardiac_biomarker

  • Proteoglycan 4
  • Proteoglycan; lubricant; gene

    water-soluble synovial fluid protein. In synovial fluid it interacts with Galectin-3 that improves its lubricating property. Lubricin's unglycosylated regions

    Proteoglycan 4

    Proteoglycan 4

    Proteoglycan_4

  • Immunoglobulin D
  • Antibody isotype

    IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44". Immunity. 49 (4): 709–724.e8. doi:10.1016/j.immuni.2018.08

    Immunoglobulin D

    Immunoglobulin D

    Immunoglobulin_D

  • Edinburgh BioQuarter
  • Office site in Edinburgh, Scotland

    Edinburgh Bioquarter. 9 June 2020. Retrieved 26 July 2022. "Galecto develops galectin modulators | Case Study". Edinburgh Bioquarter. 3 December 2020. Retrieved

    Edinburgh BioQuarter

    Edinburgh BioQuarter

    Edinburgh_BioQuarter

  • Cardiorenal syndrome
  • When dysfunction of the kidneys or heart induces dysfunction in the other

    the diagnosis of CRS. Though less frequently used in clinical practice, Galectin-3 and ST2 (suppressor of tumorigenicity 2), markers of fibrosis and myocardial

    Cardiorenal syndrome

    Cardiorenal_syndrome

  • Ana Anderson
  • American researcher and immunologist

    Schubart; et al. (December 2005). "The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity". Nature Immunology. 6 (12): 1245–52. doi:10

    Ana Anderson

    Ana_Anderson

  • Jo Douglass
  • Australian asthma researcher

    Health Press Ltd, Oxford UK. 2013 Chua JC, Douglass JA, et al. (2012) Galectin-10, a Potential Biomarker of Eosinophilic Airway Inflam. PLoS ONE 7(8):

    Jo Douglass

    Jo_Douglass

  • Alexa Fluor
  • Family of fluorescent dyes

    2011). "Fungal Recognition is Mediated by the Association of Dectin-1 and Galectin-3 in Macrophages". Proc. Natl. Acad. Sci. U.S.A. 108 (34): 14270–14275

    Alexa Fluor

    Alexa_Fluor

  • Integrin alpha 3
  • Mammalian protein found in Homo sapiens

    Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (July 2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". J

    Integrin alpha 3

    Integrin alpha 3

    Integrin_alpha_3

  • Co-stimulation
  • Signal to activate immune cells

    expressed mainly on T cells, but also on NK cells. Due to extracellular galectin 9 binding, 41-BB complexes are kept preassembled on the membrane. It interacts

    Co-stimulation

    Co-stimulation

  • Richard D. Cummings
  • American biochemist

    comprehensive overview of the emerging field of glycomics, and a co-editor of Galectins: Methods and Protocols. In addition, Cummings currently has 32 US Patents

    Richard D. Cummings

    Richard_D._Cummings

  • LAMP2
  • Protein-coding gene in the species Homo sapiens

    "Expression of Lamp-1 and Lamp-2 and their interactions with galectin-3 in human tumor cells". International Journal of Cancer. 75 (1): 105–11. doi:10

    LAMP2

    LAMP2

    LAMP2

  • Anti–Saccharomyces cerevisiae antibody
  • Immune response to yeast

    Chemically Induced Colitis and Augments Inflammatory Responses through Galectin-3". The Journal of Infectious Diseases. 197 (7): 972–980. doi:10.1086/528990

    Anti–Saccharomyces cerevisiae antibody

    Anti–Saccharomyces_cerevisiae_antibody

  • CLEC1B
  • Protein-coding gene in humans

    termed aggretin); hemin (an iron-containing porphyrin containing chlorine); galectin-9; the human immunodeficiency virus (which causes the acquired immunodeficiency

    CLEC1B

    CLEC1B

    CLEC1B

  • PDPN
  • Human protein

    rhodocytin (a platelet-activating snake venom also termed aggretin), hemin, galectin-9, dextran sulfate, sulfated polysaccharides, fucoidan, ketacine (i.e.

    PDPN

    PDPN

    PDPN

  • Immune checkpoint
  • Regulators of the immune system

    Th1/Tc1 function by triggering cell death upon interaction with its ligand, galectin-9. VISTA: Short for V-domain Ig suppressor of T cell activation, VISTA

    Immune checkpoint

    Immune checkpoint

    Immune_checkpoint

  • Infectious tolerance
  • brief history and perspective". European Journal of Immunology. 37 (Suppl 1): S116–123. doi:10.1002/eji.200737593. ISSN 0014-2980. PMID 17972355. Qin

    Infectious tolerance

    Infectious_tolerance

  • CDH17
  • Protein-coding gene in humans

    "Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas". Cancer Sci. 94 (5): 425–30

    CDH17

    CDH17

    CDH17

AI & ChatGPT searchs for online references containing GALECTIN 1

GALECTIN 1

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GALECTIN 1

  • VALENTINE
  • Female

    English

    VALENTINE

    Feminine form of French Valentin, VALENTINE means "healthy, strong." Compare with masculine Valentine.

    VALENTINE

  • Millen
  • Surname or Lastname

    Irish

    Millen

    Irish : variant of Mullen.English : from Old French Milon, an inflected form of the personal name Miles (see Miles 1).English : from Middle English milne, adjectival form of mille ‘mill’, or perhaps a topographic name for someone living in a lane leading to a mill, from Middle English mille, milne ‘mill’ + lane, lone ‘lane’.Dutch : patronymic from Miele 3.

    Millen

  • Ellick
  • Surname or Lastname

    Americanized form of German Illig. One family bearing this name and known to have made this change in form came to OH from Alsace in the 19th century.English

    Ellick

    Americanized form of German Illig. One family bearing this name and known to have made this change in form came to OH from Alsace in the 19th century.English : habitational name from either of two places called Elwick, in North Yorkshire and Northumberland, named with the Old English personal name Ella (or in the case of the first, possibly an unattested Ægla) + Old English wīc ‘outlying (dairy) farm’.

    Ellick

  • VALENTIN
  • Male

    French

    VALENTIN

     French form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.

    VALENTIN

  • VALENTIN
  • Male

    German

    VALENTIN

     German form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.

    VALENTIN

  • Freese
  • Surname or Lastname

    North German form of Fries 1.Dutch

    Freese

    North German form of Fries 1.Dutch : variant of Frese.English : metonymic occupational name for a weaver of frieze, a coarse woolen cloth with a thick nap, Old French frise.

    Freese

  • VALENTIN
  • Male

    Swedish

    VALENTIN

     Swedish form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.

    VALENTIN

  • Miers
  • Surname or Lastname

    English

    Miers

    English : patronymic from a variant spelling of Mayer 1.English : variant of Myers.Spanish : variant of Mier 2.Dutch : variant of Mier 3.Dutch (van der Miers) : variant of Meers 2.

    Miers

  • Miles
  • Surname or Lastname

    English (of Norman origin)

    Miles

    English (of Norman origin) : via Old French from the Germanic personal name Milo, of unknown etymology. The name was introduced to England by the Normans in the form Miles (oblique case Milon). In English documents of the Middle Ages the name sometimes appears in the Latinized form Milo (genitive Milonis), although the normal Middle English form was Mile, so the final -s must usually represent the possessive ending, i.e. ‘son or servant of Mile’.English : patronymic from the medieval personal name Mihel, an Old French contracted form of Michael.English : occupational name for a servant or retainer, from Latin miles ‘soldier’, sometimes used as a technical term in this sense in medieval documents.Irish (County Mayo) : when not the same as 1 or 3, an Anglicized form of Gaelic Ó Maolmhuire, Myles being used as the English equivalent of the Gaelic personal name Maol Muire (see Mullery).Jewish (eastern Ashkenazic) : unexplained.Dutch : variant of Miels, a variant of Miele 3.John Miles or Myles (c.1621–83), born probably in Herefordshire, England, was a pioneer American Baptist minister who emigrated to New England in 1662 and had a pastorate in Swansea, MA. Many of his descendants spell their name Myles.

    Miles

  • Mills
  • Surname or Lastname

    English and Scottish

    Mills

    English and Scottish : variant of Mill 1.English : either a metronymic form of Mill 2, or a variant of Miles.Irish : in Ulster this is the English name, but elsewhere in Ireland it may be a translation of a Gaelic topographic byname, an Mhuilinn ‘of the mill’.

    Mills

  • Michael
  • Surname or Lastname

    English, German, Dutch, and Jewish

    Michael

    English, German, Dutch, and Jewish : from the personal name Michael, ultimately from Hebrew Micha-el ‘Who is like God?’. This was borne by various minor Biblical characters and by one of the archangels, the protector of Israel (Daniel 10:13, 12:1; Rev. 12:7). In Christian tradition, Michael was regarded as the warrior archangel, conqueror of Satan, and the personal name was correspondingly popular throughout Europe, especially in knightly and military families. In English-speaking countries, this surname is also found as an Anglicized form of several Greek surnames having Michael as their root, for example Papamichaelis ‘Michael the priest’ and patronymics such as Michaelopoulos.

    Michael

  • Valentin
  • Boy/Male

    American, Australian, Basque, Chinese, Finnish, French, German, Latin, Spanish, Swedish

    Valentin

    Healthy; Strong; Valiant; The Name of More than 50 Saints and Three Roman Emperors

    Valentin

  • Mifflin
  • Surname or Lastname

    English

    Mifflin

    English : unexplained.John Mifflin (born 1640) came to Delaware from Warminster, Wiltshire, England, in the 1670s. He is probably the same person as the John Mifflin, a Quaker, who built his home, ‘Fountain Green’, in Fairmont Park, Philadelphia, in 1679. His fourth-generation descendant Thomas Mifflin (1744–1800) was a member of the Continental Congress, a revolutionary soldier, and governor of PA.

    Mifflin

  • VALENTIN
  • Male

    Danish

    VALENTIN

    , healthy.

    VALENTIN

  • Morie
  • Surname or Lastname

    Scottish spelling of Irish Morey 1.English and French

    Morie

    Scottish spelling of Irish Morey 1.English and French : from the personal name Amaury (see Morey 2).

    Morie

  • Middleton
  • Surname or Lastname

    English and Scottish

    Middleton

    English and Scottish : habitational name from any of the places so called. In over thirty instances from many different areas, the name is from Old English midel ‘middle’ + tūn ‘enclosure’, ‘settlement’. However, Middleton on the Hill near Leominster in Herefordshire appears in Domesday Book as Miceltune, the first element clearly being Old English micel ‘large’, ‘great’. Middleton Baggot and Middleton Priors in Shropshire have early spellings that suggest gem̄ðhyll (from gem̄ð ‘confluence’ + hyll ‘hill’) + tūn as the origin.A Scottish family of this name derives it from lands at Middleto(u)n near Kincardine. The Scottish physician Peter Middleton practiced in New York City after 1752 and was one of the founders of the medical school at King's College (now Columbia University) in 1767. One of the earliest of the Charleston, SC, Middleton family of prominent legislators was Arthur Middleton, born in Charleston in 1681.

    Middleton

  • Mobbs
  • Surname or Lastname

    English (Norfolk)

    Mobbs

    English (Norfolk) : metronymic from the medieval female personal name Mab(be) (see Mapp 1).

    Mobbs

  • Mille
  • Surname or Lastname

    French

    Mille

    French : from the Germanic personal name Milo (see Miles 1).English : variant spelling of Mill.Dutch : variant of Miele.

    Mille

  • Valentin
  • Boy/Male

    Swedish American Latin Spanish

    Valentin

    Brave.

    Valentin

  • Part 1 and 2'
  • Boy/Male

    Shakespearean

    Part 1 and 2'

    King Henry IV, Part 1' Earl of March. Scroop.

    Part 1 and 2'

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GALECTIN 1

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GALECTIN 1

Online names & meanings

  • Ambaalika
  • Girl/Female

    Hindu, Indian, Malayalam, Marathi

    Ambaalika

    Mother

  • PETRI
  • Male

    Finnish

    PETRI

     Finnish form of Greek Petros, PETRI means "rock, stone." Compare with another form of Petri.

  • Hallaway
  • Surname or Lastname

    English

    Hallaway

    English : variant of Alaway, from the Old English personal name Æðelwīg, composed of the elements æðel ‘noble’ + wīg ‘war’.

  • Thayanban | தயாந்பந
  • Boy/Male

    Tamil

    Thayanban | தயாந்பந

    Devoted to ones mother

  • Chalsia
  • Girl/Female

    Indian

    Chalsia

    Landing place or port, Seaport. place name

  • Anisa
  • Girl/Female

    Muslim

    Anisa

    Affectionate.

  • Smales
  • Surname or Lastname

    English

    Smales

    English : patronymic from Small.

  • Anenasya
  • Boy/Male

    Indian, Sanskrit

    Anenasya

    Freedom from Sin; Pious; Pure

  • Kerwin
  • Boy/Male

    Christian & English(British/American/Australian)

    Kerwin

    Dark Skinned

  • Yagneshwar | யஜ்ஞேஷ்வர
  • Boy/Male

    Tamil

    Yagneshwar | யஜ்ஞேஷ்வர

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GALECTIN 1

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GALECTIN 1

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GALECTIN 1

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Other words and meanings similar to

GALECTIN 1

AI search in online dictionary sources & meanings containing GALECTIN 1

GALECTIN 1

  • Victoria
  • n.

    An asteroid discovered by Hind in 1850; -- called also Clio.

  • Volator
  • n.

    Same as Volador, 1.

  • Galactic
  • a.

    Of or pertaining to the galaxy or Milky Way.

  • Villein
  • n.

    See Villain, 1.

  • Galactin
  • n.

    An amorphous, gummy carbohydrate resembling gelose, found in the seeds of leguminous plants, and yielding on decomposition several sugars, including galactose.

  • Vintage
  • n.

    The produce of the vine for one season, in grapes or in wine; as, the vintage is abundant; the vintage of 1840.

  • Waldenses
  • n. pl.

    A sect of dissenters from the ecclesiastical system of the Roman Catholic Church, who in the 13th century were driven by persecution to the valleys of Piedmont, where the sect survives. They profess substantially Protestant principles.

  • Volt
  • n.

    The unit of electro-motive force; -- defined by the International Electrical Congress in 1893 and by United States Statute as, that electro-motive force which steadily applied to a conductor whose resistance is one ohm will produce a current of one ampere. It is practically equivalent to / the electro-motive force of a standard Clark's cell at a temperature of 15¡ C.

  • Vesbium
  • n.

    A rare metallic element of which little is known. It is said by Scacchi to have been extracted from a yellowish incrustation from the cracks of a Vesuvian lava erupted in 1631.

  • Galactic
  • a.

    Of or pertaining to milk; got from milk; as, galactic acid.

  • Volapuk
  • n.

    Literally, world's speech; the name of an artificial language invented by Johan Martin Schleyer, of Constance, Switzerland, about 1879.

  • Vocal
  • a.

    Consisting of, or characterized by, voice, or tone produced in the larynx, which may be modified, either by resonance, as in the case of the vowels, or by obstructive action, as in certain consonants, such as v, l, etc., or by both, as in the nasals m, n, ng; sonant; intonated; voiced. See Voice, and Vowel, also Guide to Pronunciation, // 199-202.

  • Vesta
  • n.

    An asteroid, or minor planet, discovered by Olbers in 1807.

  • Ward
  • a.

    The act of guarding; watch; guard; guardianship; specifically, a guarding during the day. See the Note under Watch, n., 1.

  • Vowel
  • n.

    A vocal, or sometimes a whispered, sound modified by resonance in the oral passage, the peculiar resonance in each case giving to each several vowel its distinctive character or quality as a sound of speech; -- distinguished from a consonant in that the latter, whether made with or without vocality, derives its character in every case from some kind of obstructive action by the mouth organs. Also, a letter or character which represents such a sound. See Guide to Pronunciation, // 5, 146-149.

  • Galactin
  • n.

    An amorphous, gelatinous substance containing nitrogen, found in milk and other animal fluids. It resembles peptone, and is variously regarded as a coagulating or emulsifying agent.

  • Galactin
  • n.

    A white waxy substance found in the sap of the South American cow tree (Galactodendron).

  • Wahabee
  • n.

    A follower of Abdel Wahab (b. 1691; d. 1787), a reformer of Mohammedanism. His doctrines prevail particularly among the Bedouins, and the sect, though checked in its influence, extends to most parts of Arabia, and also into India.

  • Grison
  • n.

    A South American animal of the family Mustelidae (Galictis vittata). It is about two feet long, exclusive of the tail. Its under parts are black. Also called South American glutton.