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INTEGRIN BETA-1

  • Integrin beta 1
  • Mammalian protein found in Homo sapiens

    Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor that in humans is encoded by the ITGB1 gene. This integrin associates with integrin

    Integrin beta 1

    Integrin beta 1

    Integrin_beta_1

  • Integrin beta 6
  • Protein-coding gene in the species Homo sapiens

    Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins

    Integrin beta 6

    Integrin beta 6

    Integrin_beta_6

  • Integrin beta 3
  • Mammalian protein found in Homo sapiens

    Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes. The

    Integrin beta 3

    Integrin beta 3

    Integrin_beta_3

  • Integrin beta 2
  • Mammalian protein found in Homo sapiens

    In molecular biology, CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one

    Integrin beta 2

    Integrin beta 2

    Integrin_beta_2

  • Integrin beta 4
  • Protein-coding gene in the species Homo sapiens

    Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene. Integrins are heterodimers composed of alpha and beta

    Integrin beta 4

    Integrin beta 4

    Integrin_beta_4

  • Integrin beta 7
  • Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the heterodimeric integrin

    Integrin beta 7

    Integrin beta 7

    Integrin_beta_7

  • Integrin beta 5
  • Protein-coding gene in the species Homo sapiens

    subunit of integrin that can interact with the integrin alpha v to form the integrin alpha v beta 5 integrin heterodimer. Integrin alpha V beta 5 is a receptor

    Integrin beta 5

    Integrin beta 5

    Integrin_beta_5

  • Integrin alpha-1
  • Mammalian protein found in Homo sapiens

    Integrin alpha-1 also CD49a is an integrin alpha subunit encoded in humans by the gene ITGA1. It makes up half of the α1β1 integrin duplex. Though CD49a

    Integrin alpha-1

    Integrin alpha-1

    Integrin_alpha-1

  • Integrin beta 8
  • Protein-coding gene in the species Homo sapiens

    Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene. This gene is a member of the integrin beta chain family and encodes a single-pass

    Integrin beta 8

    Integrin beta 8

    Integrin_beta_8

  • Integrin subunit beta like 1
  • Protein-coding gene in the species Homo sapiens

    Integrin subunit beta like 1 is a protein that in humans is encoded by the ITGBL1 gene. This gene encodes a beta integrin-related protein that is a member

    Integrin subunit beta like 1

    Integrin subunit beta like 1

    Integrin_subunit_beta_like_1

  • VLA-4
  • Integrin dimer

    Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the

    VLA-4

    VLA-4

    VLA-4

  • Integrin alpha X
  • Mammalian protein found in Homo sapiens

    protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain

    Integrin alpha X

    Integrin alpha X

    Integrin_alpha_X

  • Integrin
  • Transmembrane receptors involved in cellular adhesion and signalling

    Integrins are transmembrane receptors that help cell–cell and cell–extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal

    Integrin

    Integrin

    Integrin

  • Alpha-v beta-3
  • αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed

    Alpha-v beta-3

    Alpha-v_beta-3

  • LPAM-1
  • Protein complex

    Integrin α4β7 (Lymphocyte Peyer’s patch adhesion molecule-1) is an integrin heterodimer composed of CD49d (alpha-4) subunit and beta-7 subunit noncovalently

    LPAM-1

    LPAM-1

  • Integrin alpha 3
  • Mammalian protein found in Homo sapiens

    Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes

    Integrin alpha 3

    Integrin alpha 3

    Integrin_alpha_3

  • Integrin alpha 5
  • Protein

    chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain

    Integrin alpha 5

    Integrin alpha 5

    Integrin_alpha_5

  • Integrin alpha E
  • Protein-coding gene in the species Homo sapiens

    encoded by the ITGAE gene. CD103 binds integrin beta 7 (β7– ITGB7) to form the complete heterodimeric integrin molecule αEβ7, which has no distinct name

    Integrin alpha E

    Integrin alpha E

    Integrin_alpha_E

  • Integrin alpha 2
  • Mammalian protein found in Homo sapiens

    common beta chain. They are found on a wide variety of cell types including T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved

    Integrin alpha 2

    Integrin alpha 2

    Integrin_alpha_2

  • CD11
  • biology, CD11 is the α (alpha) component of various integrins, especially ones in which the β (beta) component is CD18 (β2) and mediate leukocyte adhesion

    CD11

    CD11

  • Integrin alpha 2b
  • Mammalian protein found in Homo sapiens

    Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are

    Integrin alpha 2b

    Integrin alpha 2b

    Integrin_alpha_2b

  • TGF beta 1
  • Protein-coding gene in the species Homo sapiens

    Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted

    TGF beta 1

    TGF beta 1

    TGF_beta_1

  • ITGB1BP1
  • Protein-coding gene in the species Homo sapiens

    Integrin beta-1-binding protein 1 is a protein that in humans is encoded by the ITGB1BP1 gene. The cytoplasmic domains of integrins are essential for

    ITGB1BP1

    ITGB1BP1

    ITGB1BP1

  • Interleukin 1 beta
  • Mammalian protein found in Homo sapiens

    Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and

    Interleukin 1 beta

    Interleukin 1 beta

    Interleukin_1_beta

  • Integrin alpha M
  • Mammalian protein found in Homo sapiens

    Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1)

    Integrin alpha M

    Integrin alpha M

    Integrin_alpha_M

  • Integrin alpha 4
  • Mammalian protein found in Homo sapiens

    alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha

    Integrin alpha 4

    Integrin alpha 4

    Integrin_alpha_4

  • Integrin alpha V
  • Mammalian protein found in Homo sapiens

    beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains

    Integrin alpha V

    Integrin alpha V

    Integrin_alpha_V

  • Integrin alpha L
  • Mammalian protein found in Homo sapiens

    containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed

    Integrin alpha L

    Integrin alpha L

    Integrin_alpha_L

  • Integrin alpha 10
  • Protein-coding gene in the species Homo sapiens

    with the integrin beta 1 chain (ITGB1) to form a novel collagen type II-binding integrin expressed in cartilage tissue. TAR syndrome 1q21.1 deletion syndrome

    Integrin alpha 10

    Integrin alpha 10

    Integrin_alpha_10

  • Stress granule
  • Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

    condensates in the cytosol composed of proteins and RNA that assemble into 0.1–2 μm membraneless organelles when the cell is under stress. The mRNA molecules

    Stress granule

    Stress granule

    Stress_granule

  • Integrin-linked kinase
  • Protein found in humans

    catalytic domain. Integrins lack enzymatic activity and depend on adapters to signal proteins. ILK is linked to beta-1 and beta-3 integrin cytoplasmic domains

    Integrin-linked kinase

    Integrin-linked kinase

    Integrin-linked_kinase

  • Transforming growth factor beta
  • Cytokine

    Dalton SL, Wu J, et al. (February 1999). "The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation

    Transforming growth factor beta

    Transforming growth factor beta

    Transforming_growth_factor_beta

  • Collagen, type XXIII, alpha 1
  • Mammalian protein found in humans

    Non-small-cell lung carcinoma Prostate cancer Homotrimer Lipid raft Integrin, beta 1 GRCh38: Ensembl release 89: ENSG00000050767 – Ensembl, May 2017 GRCm38:

    Collagen, type XXIII, alpha 1

    Collagen, type XXIII, alpha 1

    Collagen,_type_XXIII,_alpha_1

  • Lymphocyte function-associated antigen 1
  • Integrin found on lymphocytes

    Lymphocyte function-associated antigen 1 (LFA-1) is an integrin found on lymphocytes and other leukocytes. LFA-1 plays a key role in emigration, which

    Lymphocyte function-associated antigen 1

    Lymphocyte_function-associated_antigen_1

  • Integrin alpha 6
  • Mammalian protein found in Homo sapiens

    alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion

    Integrin alpha 6

    Integrin alpha 6

    Integrin_alpha_6

  • Integrin alpha 8
  • Protein-coding gene in the species Homo sapiens

    soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds to

    Integrin alpha 8

    Integrin alpha 8

    Integrin_alpha_8

  • Sigvotatug vedotin
  • Experimental antibody-drug conjugate targeting integrin beta-6 for solid tumors

    sigvotatug vedotin is composed of a monoclonal antibody directed against integrin beta-6 (IB6), conjugated to the cytotoxic payload monomethyl auristatin E

    Sigvotatug vedotin

    Sigvotatug_vedotin

  • Integrin alpha 9
  • Protein-coding gene in the species Homo sapiens

    encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell

    Integrin alpha 9

    Integrin alpha 9

    Integrin_alpha_9

  • Vedolizumab
  • Medication used for the treatment of gastro-intestinal diseases

    to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7), blocking the α4β7 integrin results

    Vedolizumab

    Vedolizumab

  • Integrin alpha 7
  • beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1. The primary binding partners of alpha-7 integrin are laminin-1

    Integrin alpha 7

    Integrin alpha 7

    Integrin_alpha_7

  • ICAM-1
  • Mammalian protein found in Homo sapiens

    to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into respiratory epithelium. ICAM-1 is

    ICAM-1

    ICAM-1

    ICAM-1

  • Integrin alpha 11
  • Protein-coding gene in the species Homo sapiens

    an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears

    Integrin alpha 11

    Integrin alpha 11

    Integrin_alpha_11

  • ITGB1BP3
  • Protein-coding gene in the species Homo sapiens

    Medicine. Li J, Mayne R, Wu C (Feb 2000). "A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation". J

    ITGB1BP3

    ITGB1BP3

    ITGB1BP3

  • TGF beta Activation
  • Garat, C.; Matthay, M. A.; et al. (1999). "The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation

    TGF beta Activation

    TGF_beta_Activation

  • Alpha-5 beta-1
  • α5β1, also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It

    Alpha-5 beta-1

    Alpha-5_beta-1

  • List of human clusters of differentiation
  • not listed on hcdm Bennett JS. Structure and function of the platelet integrin alphaIIbbeta3. J Clin Invest 2005; 115:3363-9. "FITC Anti-human CD51 Antibody

    List of human clusters of differentiation

    List_of_human_clusters_of_differentiation

  • Ga-68-Trivehexin
  • Contrast agent for cancer imaging

    (LAP) in its complex with transforming growth factor beta 1 (TGF-β1). Binding of αvβ6-integrin to LAP releases and thus, activates TGF-β1. In early-stage

    Ga-68-Trivehexin

    Ga-68-Trivehexin

    Ga-68-Trivehexin

  • FERMT3
  • Protein-coding gene in the species Homo sapiens

    β(2) integrin function depend on both cell type (Natural killer cell or Leukocytes) and the integrin activation stimulus. The prevention of the beta-3 activation

    FERMT3

    FERMT3

    FERMT3

  • Alpha 5
  • Topics referred to by the same term

    the Power Rangers franchise Integrin alpha-5, a protein encoded by the ITGA5 gen in humans Alpha-5 beta-1 (α5β1), an integrin that binds to matrix macromolecules

    Alpha 5

    Alpha_5

  • Integrin alpha D
  • Protein-coding gene in the species Homo sapiens

    of a novel gene-encoding a human beta 2-integrin alpha subunit". Gene. 171 (2): 291–4. doi:10.1016/0378-1119(95)00869-1. PMID 8666289. Shelley CS, Da Silva

    Integrin alpha D

    Integrin alpha D

    Integrin_alpha_D

  • Collagen, type XVII, alpha 1
  • Mammalian protein found in humans

    intracellular domains of bullous pemphigoid antigen 2 (BP180) and beta 4 integrin, hemidesmosomal components of basal keratinocytes". Biochemical and

    Collagen, type XVII, alpha 1

    Collagen, type XVII, alpha 1

    Collagen,_type_XVII,_alpha_1

  • G protein
  • Type of proteins

    alpha (Gα), beta (Gβ) and gamma (Gγ) subunits. In addition, the beta and gamma subunits can form a stable dimeric complex referred to as the beta-gamma complex

    G protein

    G protein

    G_protein

  • Photo-reactive amino acid analog
  • mediates cell survival in vitro via interaction with integrin beta 1 and activation of integrin-linked kinase. J. Biol. Chem. doi:10.1074/jbc.M706563200

    Photo-reactive amino acid analog

    Photo-reactive_amino_acid_analog

  • ADAM2
  • Protein-coding gene in humans

    evidence that mouse egg alpha6beta1 integrin is the receptor for sperm fertilinbeta". Chemistry & Biology. 6 (1): 1–10. doi:10.1016/S1074-5521(99)80015-5

    ADAM2

    ADAM2

    ADAM2

  • TGOLN2
  • Protein-coding gene in the species Homo sapiens

    "The luminal domain of TGN38 interacts with integrin beta 1 and is involved in its trafficking". Traffic. 1 (9): 713–23. doi:10.1034/j.1600-0854.2000.010904

    TGOLN2

    TGOLN2

    TGOLN2

  • Liver regeneration
  • Natural regrowth of damaged liver tissue

    extracellular matrix (ECM). ECM remodeling initiates signaling impulses through integrin and leads to the release of local growth factors. The cascade starts with

    Liver regeneration

    Liver_regeneration

  • Fibrillin-1
  • Protein found in humans

    eight-cysteine domains homologous with latent TGF-beta binding protein, and a proline-rich region. The FBN-1 gene is involved in a variety of embryonic developmental

    Fibrillin-1

    Fibrillin-1

    Fibrillin-1

  • Juxtacrine signalling
  • Contact-based cell-cell signalling

    cell communication. Cells use mainly the receptor integrin to interact with ECM proteins. Integrins are a family of receptor proteins that integrate the

    Juxtacrine signalling

    Juxtacrine signalling

    Juxtacrine_signalling

  • PI3K/AKT/mTOR pathway
  • Cell cycle regulation pathway

    many known factors that enhance the PI3K/AKT pathway including EGF, shh, IGF-1, insulin, and calmodulin. Both leptin and insulin recruit PI3K signalling

    PI3K/AKT/mTOR pathway

    PI3K/AKT/mTOR pathway

    PI3K/AKT/mTOR_pathway

  • Thrombospondin 1
  • Protein-coding gene in the species Homo sapiens

    and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. The thrombospondin-1 protein

    Thrombospondin 1

    Thrombospondin 1

    Thrombospondin_1

  • Cedelizumab
  • Monoclonal antibody

    antibody, which binds to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7) on T lymphocytes

    Cedelizumab

    Cedelizumab

  • Cell adhesion molecule
  • Subset of cell adhesion proteins

    transcription. Integrins are heterodimeric, as they consist of an alpha and beta subunit. There are currently 18 alpha subunits and 8 beta subunits, which

    Cell adhesion molecule

    Cell_adhesion_molecule

  • Laminin, beta 1
  • Protein-coding gene in the species Homo sapiens

    (2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". J. Cell

    Laminin, beta 1

    Laminin, beta 1

    Laminin,_beta_1

  • Neuropeptide
  • Peptides released by neurons as intercellular messengers

    VIP Substance P Dopamine Cholecystokinin Neurotensin Glucagon-like peptide-1 (in the nucleus accumbens) Epinephrine (adrenaline) Neuropeptide Y Neurotensin

    Neuropeptide

    Neuropeptide

    Neuropeptide

  • Mechanotransduction
  • Conversion of mechanical stimulus of a cell into electrochemical activity

    extracellular matrix ligands, integrins are also receptive to autocrine and paracrine signals such as growth factors in the TGF-beta family. Chondrocytes have

    Mechanotransduction

    Mechanotransduction

    Mechanotransduction

  • Cilengitide
  • Chemical compound

    "Nanomolar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins". Journal of Medicinal Chemistry. 45 (5): 1045–51

    Cilengitide

    Cilengitide

    Cilengitide

  • Transforming growth factor beta superfamily
  • Protein family

    factor-beta (TGF-beta) is a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. TGF-beta-1 is a

    Transforming growth factor beta superfamily

    Transforming growth factor beta superfamily

    Transforming_growth_factor_beta_superfamily

  • Notch signaling pathway
  • Series of molecular signals

    redundant Notch homologs, glp-1 and lin-12. During C. elegans, GLP-1, the C. elegans Notch homolog, interacts with APX-1, the C. elegans Delta homolog

    Notch signaling pathway

    Notch signaling pathway

    Notch_signaling_pathway

  • Signal transduction
  • Cascade of intracellular and molecular events for transmission/amplification of signals

    PMID 17084981. Gilcrease MZ (March 2007). "Integrin signaling in epithelial cells". Cancer Letters. 247 (1): 1–25. doi:10.1016/j.canlet.2006.03.031. PMID 16725254

    Signal transduction

    Signal transduction

    Signal_transduction

  • TGF beta 2
  • Protein-coding gene in the species Homo sapiens

    Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during

    TGF beta 2

    TGF beta 2

    TGF_beta_2

  • Receptor for activated C kinase 1
  • Protein-coding gene in the species Homo sapiens

    "Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit". The Journal of Biological Chemistry. 273 (4): 2379–83. doi:10

    Receptor for activated C kinase 1

    Receptor for activated C kinase 1

    Receptor_for_activated_C_kinase_1

  • Caveolin 1
  • Protein found in humans

    most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting

    Caveolin 1

    Caveolin 1

    Caveolin_1

  • Ligand (biochemistry)
  • Substance that forms a complex with a biomolecule

    1982). "Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites".

    Ligand (biochemistry)

    Ligand (biochemistry)

    Ligand_(biochemistry)

  • TLN1
  • Protein-coding gene in the species Homo sapiens

    cells. Talin-1 functions to mediate cell-cell adhesion via the linkage of integrins to the actin cytoskeleton and in the activation of integrins. Altered

    TLN1

    TLN1

    TLN1

  • Laminin, beta 2
  • Protein-coding gene in the species Homo sapiens

    2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". Journal

    Laminin, beta 2

    Laminin, beta 2

    Laminin,_beta_2

  • Mammary gland
  • Exocrine gland in humans and other mammals

    differentiation sub-locally. Important players include beta-1 integrin, epidermal growth factor receptor (EGFR), laminin-1/5, collagen-IV, matrix metalloproteinase

    Mammary gland

    Mammary gland

    Mammary_gland

  • Alpha chain
  • Subunit of a protein

    the T-cell receptor, the fibrinogen alpha chain, the integrin alpha chain, Hemoglobin, alpha 1 It should be distinguished from the term alpha helix,

    Alpha chain

    Alpha_chain

  • Collagen, type III, alpha 1
  • Mammalian protein

    (monomers), each called an alpha 1 chain of type III collagen. Formally, the monomers are called collagen type III, alpha-1 chain and in humans are encoded

    Collagen, type III, alpha 1

    Collagen, type III, alpha 1

    Collagen,_type_III,_alpha_1

  • Platelet membrane glycoprotein
  • Surface glycoproteins involved in hemostasis

    Calvete JJ (1995). "On the structure and function of platelet integrin alpha IIb beta 3, the fibrinogen receptor". Proc. Soc. Exp. Biol. Med. 208 (4):

    Platelet membrane glycoprotein

    Platelet_membrane_glycoprotein

  • Timothy A. Springer
  • American immunologist

    (16 July 1993). "Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1". Cell. 74 (1): 185–195. doi:10.1016/0092-8674(93)90305-A

    Timothy A. Springer

    Timothy_A._Springer

  • Addressin
  • Protein found in humans

    structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences".

    Addressin

    Addressin

    Addressin

  • Tyrosine-protein kinase SYK
  • Enzyme

    Dib K (March 2003). "Fgr but not Syk tyrosine kinase is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophils"

    Tyrosine-protein kinase SYK

    Tyrosine-protein kinase SYK

    Tyrosine-protein_kinase_SYK

  • Insulin-like growth factor 1
  • Protein found in humans

    Insulin-like growth factor 1 (IGF1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in

    Insulin-like growth factor 1

    Insulin-like growth factor 1

    Insulin-like_growth_factor_1

  • Fibronectin
  • Protein involved in cell adhesion, cell growth, cell migration and differentiation

    extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as

    Fibronectin

    Fibronectin

    Fibronectin

  • CD63
  • Mammalian protein found in humans

    "Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29)". Journal of Immunology

    CD63

    CD63

    CD63

  • Laminin
  • Protein in the extracellular matrix

    secreted by Schwann cells. Neurons of the peripheral nervous system express integrin receptors that attach to laminins and promote neuroregeneration after injury

    Laminin

    Laminin

    Laminin

  • Adhesion molecule (immunoglobulin-like)
  • Protein domain

    structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition". Structure. 6 (6): 793–801. doi:10

    Adhesion molecule (immunoglobulin-like)

    Adhesion molecule (immunoglobulin-like)

    Adhesion_molecule_(immunoglobulin-like)

  • Vitaxin
  • Pharmaceutical compound

    (MEDI-523) is a humanized monoclonal antibody against the vascular integrin alpha-v beta-3. It is shown to be a promising angiogenesis inhibitor used in

    Vitaxin

    Vitaxin

  • TGF beta signaling pathway
  • Signaling pathway involving transforming growth factor beta proteins

    The transforming growth factor beta (TGFβ) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo

    TGF beta signaling pathway

    TGF_beta_signaling_pathway

  • Disintegrin
  • Proteins from viper venom inhibiting platelets aggregation

    clumping of platelets. They interact with the beta-1 and -3 families of integrins receptors. Integrins are cell receptors involved in cell–cell and cell–extracellular

    Disintegrin

    Disintegrin

    Disintegrin

  • PTK2B
  • Protein-coding gene in humans

    alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility". J. Cell Biol. 152 (1): 181–95. doi:10.1083/jcb.152.1.181. PMC 2193648

    PTK2B

    PTK2B

    PTK2B

  • CIB1
  • Protein-coding gene in humans

    protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3). CIB1 is a small protein

    CIB1

    CIB1

    CIB1

  • Natalizumab
  • Medication used to treat multiple sclerosis and Crohn's disease

    a humanized monoclonal antibody against the cell adhesion molecule α4-integrin. It is given by intravenous infusion. The drug is believed to work by reducing

    Natalizumab

    Natalizumab

    Natalizumab

  • Tenascin C
  • Human protein-coding gene

    J, Balmes J, Sheppard D (May 1995). "Distribution of integrins alpha v beta 6 and alpha 9 beta 1 and their known ligands, fibronectin and tenascin, in

    Tenascin C

    Tenascin C

    Tenascin_C

  • Focal adhesion
  • Structures which transmit force and signals between a cell and the extracellular matrix

    the DGEA and GFOGER motifs found in collagen. Integrins are heterodimers which are formed from one beta and one alpha subunit. These subunits are present

    Focal adhesion

    Focal adhesion

    Focal_adhesion

  • Connective tissue growth factor
  • Protein found in humans

    Ugarova TP, Ye RD, Lau LF, Lam SC (June 2002). "Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61

    Connective tissue growth factor

    Connective tissue growth factor

    Connective_tissue_growth_factor

  • Periostin
  • Protein-coding gene in the species Homo sapiens

    POSTN gene. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells. Periostin

    Periostin

    Periostin

    Periostin

  • Biological therapy for inflammatory bowel disease
  • Medical treatment

    trials for Crohn's disease. Etrolizumab is an integrin receptor antagonist that targets beta 7 integrins. Etrolizumab has shown efficacy in phase 2 trials

    Biological therapy for inflammatory bowel disease

    Biological therapy for inflammatory bowel disease

    Biological_therapy_for_inflammatory_bowel_disease

  • Stromal cell-derived factor 1
  • Mammalian protein found in Homo sapiens

    expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of

    Stromal cell-derived factor 1

    Stromal cell-derived factor 1

    Stromal_cell-derived_factor_1

  • Autocrine signaling
  • Signaling within the same cell

    Chung, Jun (2004). "Autocrine signaling in carcinoma: VEGF and the α6β4 integrin". Seminars in Cancer Biology. 14 (2): 115–22. doi:10.1016/j.semcancer.2003

    Autocrine signaling

    Autocrine signaling

    Autocrine_signaling

AI & ChatGPT searchs for online references containing INTEGRIN BETA-1

INTEGRIN BETA-1

AI search references containing INTEGRIN BETA-1

INTEGRIN BETA-1

  • MacBeth
  • Boy/Male

    Scottish Shakespearean

    MacBeth

    Son of Beth.

    MacBeth

  • Beta
  • Girl/Female

    Greek Hebrew English

    Beta

    From the Hebrew Elisheba, meaning either oath of God, or God is satisfaction. Famous bearer: Old...

    Beta

  • LETA
  • Female

    Spanish

    LETA

     Short form of Spanish Aleta, LETA means "winged." Compare with another form of Leta.

    LETA

  • NETA
  • Female

    Hebrew

    NETA

    (נֶטַע) Hebrew unisex name NETA means meaning "plant, shrub."

    NETA

  • Ekatala
  • Boy/Male

    Hindu, Indian, Sanskrit

    Ekatala

    Emperor; Single Beat

    Ekatala

  • META
  • Female

    German

    META

    Short form of German Margarete, META means "pearl."

    META

  • Spandan
  • Boy/Male

    Bengali, Hindu, Indian, Sanskrit

    Spandan

    Heart Beat

    Spandan

  • BETA
  • Female

    English

    BETA

    English name derived from the second letter of the Greek alphabet, beta, related to Hebrew bet, BETA means "house." 

    BETA

  • BET
  • Female

    English

    BET

    Short form of English Elizabeth, BET means "God is my oath." 

    BET

  • BELA
  • Male

    Hebrew

    BELA

    (בֶּלַע) Hebrew name BELA means "destruction." In the bible, this is the name of several characters, including a king of Edom.

    BELA

  • PETA
  • Female

    Native American

    PETA

     Native American Blackfoot name PETA means "golden eagle." Compare with another form of Peta.

    PETA

  • BERTA
  • Female

    English

    BERTA

    Czech and Polish form of German Bertha, BERTA means "bright."

    BERTA

  • BETH
  • Female

    English

    BETH

    Short form of English Elizabeth, BETH means "God is my oath." 

    BETH

  • Pranjavi
  • Girl/Female

    Indian, Marathi

    Pranjavi

    Our Heart Beat

    Pranjavi

  • ZETA
  • Female

    Italian

    ZETA

     Variant spelling of Italian Zita, ZETA means "little girl." Compare with another form of Zeta.

    ZETA

  • BEA
  • Female

    English

    BEA

    Short form of English Beatrix, BEA means "voyager (through life)." 

    BEA

  • ELÅ»BIETA
  • Female

    Polish

    ELŻBIETA

    Polish form of Greek Elisabet, ELŻBIETA means "God is my oath."

    ELŻBIETA

  • BEATA
  • Female

    Polish

    BEATA

    Polish name derived from Latin beatus, BEATA means "blessed." 

    BEATA

  • Beth-shemesh
  • Biblical

    Beth-shemesh

    Beth (Hebrew)|house of the sun

    Beth-shemesh

  • ERZSÉBET
  • Female

    Hungarian

    ERZSÉBET

    Hungarian form of Greek Elisabet, ERZSÉBET means "God is my oath."

    ERZSÉBET

AI search queries for Facebook and twitter posts, hashtags with INTEGRIN BETA-1

INTEGRIN BETA-1

Follow users with usernames @INTEGRIN BETA-1 or posting hashtags containing #INTEGRIN BETA-1

INTEGRIN BETA-1

Online names & meanings

  • IVANKA
  • Female

    Bulgarian

    IVANKA

    , Jehovah's gift (or grace).

  • Shashibhushan
  • Boy/Male

    Hindu, Indian, Kannada, Malayalam, Marathi, Telugu

    Shashibhushan

    Lord Shiva; One who Wears Moon as Ornament

  • Izzard
  • Surname or Lastname

    English

    Izzard

    English : variant spelling of Izard.

  • Anik | அநிக
  • Boy/Male

    Tamil

    Anik | அநிக

    Lord Ganesh, Soldier, Many

  • Pushtika
  • Girl/Female

    Hindu, Indian

    Pushtika

    Well Nourished Girl

  • Fadwa
  • Girl/Female

    Indian

    Fadwa

    Self sacrificing

  • Duryab |
  • Boy/Male

    Muslim

    Duryab |

    Finder of good things

  • Datrim
  • Boy/Male

    Hindu, Indian

    Datrim

    Peaceful

  • Lakhani
  • Boy/Male

    Hindu, Indian

    Lakhani

    Rich

  • Sihon
  • Biblical

    Sihon

    rooting out; conclusion

AI search & ChatGPT queries for Facebook and twitter users, user names, hashtags with INTEGRIN BETA-1

INTEGRIN BETA-1

Top AI & ChatGPT search, Social media, medium, facebook & news articles containing INTEGRIN BETA-1

INTEGRIN BETA-1

AI searchs for Acronyms & meanings containing INTEGRIN BETA-1

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AI searches, Indeed job searches and job offers containing INTEGRIN BETA-1

Other words and meanings similar to

INTEGRIN BETA-1

AI search in online dictionary sources & meanings containing INTEGRIN BETA-1

INTEGRIN BETA-1

  • Beat
  • v. i.

    A cheat or swindler of the lowest grade; -- often emphasized by dead; as, a dead beat.

  • Beat
  • n.

    A recurring stroke; a throb; a pulsation; as, a beat of the heart; the beat of the pulse.

  • Bet
  • imp. & p. p.

    of Bet

  • Beat
  • v. i.

    To make a sound when struck; as, the drums beat.

  • Beat
  • v. i.

    A round or course which is frequently gone over; as, a watchman's beat.

  • Beat
  • v. i.

    To make a succession of strokes on a drum; as, the drummers beat to call soldiers to their quarters.

  • Dry-beat
  • v. t.

    To beat severely.

  • Wager
  • v. t.

    That on which bets are laid; the subject of a bet.

  • Beat
  • imp.

    of Beat

  • Beat
  • v. t.

    To strike repeatedly; to lay repeated blows upon; as, to beat one's breast; to beat iron so as to shape it; to beat grain, in order to force out the seeds; to beat eggs and sugar; to beat a drum.

  • Beat
  • v. t.

    To give the signal for, by beat of drum; to sound by beat of drum; as, to beat an alarm, a charge, a parley, a retreat; to beat the general, the reveille, the tattoo. See Alarm, Charge, Parley, etc.

  • Integrity
  • n.

    The state or quality of being entire or complete; wholeness; entireness; unbroken state; as, the integrity of an empire or territory.

  • Integral
  • a.

    Pertaining to, or proceeding by, integration; as, the integral calculus.

  • Beat
  • p. p.

    of Beat

  • Integral
  • a.

    Essential to completeness; constituent, as a part; pertaining to, or serving to form, an integer; integrant.

  • To-beat
  • v. t.

    To beat thoroughly or severely.

  • Intern
  • a.

    To put for safe keeping in the interior of a place or country; to confine to one locality; as, to intern troops which have fled for refuge to a neutral country.

  • Integrant
  • a.

    Making part of a whole; necessary to constitute an entire thing; integral.