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GRB7

  • GRB7
  • Protein-coding gene in the species Homo sapiens

    factor receptor-bound protein 7, also known as GRB7, is a protein that in humans is encoded by the GRB7 gene. The product of this gene belongs to a small

    GRB7

    GRB7

    GRB7

  • HER2
  • Mammalian protein found in humans

    carcinomas. The ERBB2 gene is physically near the gene encoding GRB7 on chromosome 17. GRB7 is a proto-oncogene associated with breast, testicular germ cell

    HER2

    HER2

    HER2

  • GSDMB
  • Protein-coding gene in the species Homo sapiens

    linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon". Int. J. Oncol. 24 (4): 757–63. doi:10.3892/ijo.24.4.757. PMID 15010812

    GSDMB

    GSDMB

    GSDMB

  • Insulin receptor
  • Cell receptor found in humans

    Resistance. Insulin receptor has been shown to interact with ENPP1, GRB10, GRB7, IRS1, MAD2L1, PRKCD, PTPN11, and SH2B1. GRCh38: Ensembl release 89: ENSG00000171105

    Insulin receptor

    Insulin receptor

    Insulin_receptor

  • List of MeSH codes (D12.776.476)
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

    List of MeSH codes (D12.776.476)

    List_of_MeSH_codes_(D12.776.476)

  • Epidermal growth factor receptor
  • Transmembrane protein

    (May 1996). "Cloning and characterization of GRB14, a novel member of the GRB7 gene family". The Journal of Biological Chemistry. 271 (21): 12502–10. doi:10

    Epidermal growth factor receptor

    Epidermal growth factor receptor

    Epidermal_growth_factor_receptor

  • KIT gene
  • Mammalian protein and protein-coding gene

    "Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor". The Biochemical Journal. 341 (1):

    KIT gene

    KIT gene

    KIT_gene

  • List of MeSH codes (D12.776.157)
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

    List of MeSH codes (D12.776.157)

    List_of_MeSH_codes_(D12.776.157)

  • List of human protein-coding genes 3
  • HGNC:4563; O75791 6618 GRAPL HGNC:37240; Q8TC17 6619 GRB2 HGNC:4566; P62993 6620 GRB7 HGNC:4567; Q14451 6621 GRB10 HGNC:4564; Q13322 6622 GRB14 HGNC:4565; Q14449

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • BPS domain
  • Protein family

    protein domain of approximately 45 amino acids found in the adaptor proteins Grb7/|Grb10/Grb14. It mediates inhibition of the tyrosine kinase domain of the

    BPS domain

    BPS domain

    BPS_domain

  • RET proto-oncogene
  • Mammalian protein

    shown to interact with: DOK1, DOK5, GDNF family receptor alpha 1, GRB10, GRB7, Grb2, SHC1, and STAT3. GRCh38: Ensembl release 89: ENSG00000165731 – Ensembl

    RET proto-oncogene

    RET proto-oncogene

    RET_proto-oncogene

  • Chromosome 17
  • Human chromosome

    oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (17q12) GRB7: Growth factor Receptor-Bound protein 7 (17q12) BRCA1: breast cancer 1, early

    Chromosome 17

    Chromosome 17

    Chromosome_17

  • GRB14
  • Protein-coding gene in the species Homo sapiens

    (May 1996). "Cloning and characterization of GRB14, a novel member of the GRB7 gene family". J. Biol. Chem. 271 (21). UNITED STATES: 12502–12510. doi:10

    GRB14

    GRB14

    GRB14

  • SH2 domain
  • Protein domain

    CRKL; CSK DAPP1 FER; FES; FGR; FRK; FYN GRAP; GRAP2; GRB10; GRB14; GRB2; GRB7 HCK; HSH2D INPP5D; INPPL1; ITK; JAK2; LCK; LCP2; LYN MATK; NCK1; NCK2 PIK3R1;

    SH2 domain

    SH2 domain

    SH2_domain

  • Pleckstrin homology domain
  • Clinical Significance

    FGD1, FGD2, FGD3, FGD4, FGD5, FGD6, GAB1, GAB2, GAB3, GAB4, GRB10, GRB14, GRB7, IRS1, IRS2, IRS4, ITK, ITSN1, ITSN2, KALRN, KIF1A, KIF1B, KIF1Bbeta, MCF2

    Pleckstrin homology domain

    Pleckstrin homology domain

    Pleckstrin_homology_domain

  • ERBB3
  • Protein found in humans

    PW, Sivertsen SP, Sasaki H, Wallasch C, et al. (March 1998). "Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target

    ERBB3

    ERBB3

    ERBB3

  • ERBB4
  • Protein-coding gene in the species Homo sapiens

    PW, Sivertsen SP, Sasaki H, Wallasch C, Daly RJ (Mar 1998). "Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target

    ERBB4

    ERBB4

    ERBB4

  • Rnd1
  • Protein-coding gene in the species Homo sapiens

    (Nobes et al., 1998).[supplied by OMIM] Rnd1 has been shown to interact with GRB7, PLXNB1, PDE6D, ARHGAP5 and UBXD5. GRCh38: Ensembl release 89: ENSG00000172602

    Rnd1

    Rnd1

    Rnd1

  • PTK2
  • Protein-coding gene in humans

    has been shown to interact with: BCAR1, BMX, CD61, CRK, DCC, FYN, GIT1, GRB7, Grb2, IRS1, ITGB5, JAK2, MAPK8IP3, NCK1, NCK2, NEDD9, NEO1, P53, PIK3R1

    PTK2

    PTK2

    PTK2

  • EPH receptor B1
  • Protein-coding gene in the species Homo sapiens

    ephrin-B family members. EPH receptor B1 has been shown to interact with: ACP1 GRB7 and NCK1 Ephrin-B2 GRCh38: Ensembl release 89: ENSG00000154928 – Ensembl

    EPH receptor B1

    EPH receptor B1

    EPH_receptor_B1

  • Stress granule
  • Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

    NP, Ho PC, Wei LN (March 2008). "Regulation of stress granule dynamics by Grb7 and FAK signalling pathway". The EMBO Journal. 27 (5): 715–726. doi:10.1038/emboj

    Stress granule

    Stress granule

    Stress_granule

  • Star related lipid transfer domain containing 3
  • linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon". International Journal of Oncology. 24 (4): 757–763. doi:10.3892/ijo

    Star related lipid transfer domain containing 3

    Star related lipid transfer domain containing 3

    Star_related_lipid_transfer_domain_containing_3

  • GRB2
  • Protein-coding gene in the species Homo sapiens

    "Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor". The Biochemical Journal. 341 (1):

    GRB2

    GRB2

    GRB2

  • RASSF9
  • Protein-coding gene in the species Homo sapiens

    ras-associating (RA)-like domain in the N-termini of band 4.1/JEF domains and in the Grb7/10/14 adapter family". Biochem Biophys Res Commun. 259 (1): 113–20. doi:10

    RASSF9

    RASSF9

    RASSF9

  • Gasdermin A
  • Protein-coding gene in the species Homo sapiens

    linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon". Int. J. Oncol. 24 (4): 757–63. doi:10.3892/ijo.24.4.757. PMID 15010812

    Gasdermin A

    Gasdermin A

    Gasdermin_A

  • Telethonin
  • Protein in the human body

    linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon". International Journal of Oncology. 24 (4): 757–63. doi:10.3892/ijo

    Telethonin

    Telethonin

    Telethonin

  • List of MeSH codes (D12.644)
  • MeSH D12.644.360.024.297 – grb2 adaptor protein MeSH D12.644.360.024.298 – grb7 adaptor protein MeSH D12.644.360.024.300 – grb10 adaptor protein MeSH D12

    List of MeSH codes (D12.644)

    List_of_MeSH_codes_(D12.644)

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