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Enzyme
3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds in humans
3α-Hydroxysteroid dehydrogenase
3α-Hydroxysteroid_dehydrogenase
Class of chemical compounds
position, hydroxysteroids are referred to as sterols, with an example being cholesterol. Hydroxysteroid dehydrogenase Ketosteroid Hydroxysteroids at the
Hydroxysteroid
Class of enzymes
17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B) (EC 1.1.1.51), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which
17β-Hydroxysteroid dehydrogenase
17β-Hydroxysteroid_dehydrogenase
Class of enzymes
enzymology, a 16alpha-hydroxysteroid dehydrogenase (EC 1.1.1.147) is an enzyme that catalyzes the chemical reaction a 16alpha-hydroxysteroid + NAD(P)+ ⇌ {\displaystyle
16-alpha-hydroxysteroid dehydrogenase
16-alpha-hydroxysteroid_dehydrogenase
Class of enzymes
3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) (EC 1.1.1.145) is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone
3β-Hydroxysteroid dehydrogenase
3β-Hydroxysteroid_dehydrogenase
Class of enzymes
In enzymology, 12alpha-hydroxysteroid dehydrogenase (EC 1.1.1.176) is an enzyme that catalyzes the chemical reaction cholic acid + NADP+ H+ H+
12alpha-hydroxysteroid dehydrogenase
12alpha-hydroxysteroid_dehydrogenase
Class of enzymes
11β-Hydroxysteroid dehydrogenase (HSD-11β or 11β-HSD) enzymes catalyze the conversion of inert 11 keto-products (e.g. cortisone) to active cortisol, or
11β-Hydroxysteroid dehydrogenase
11β-Hydroxysteroid_dehydrogenase
Medical condition
Congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency is an uncommon form of congenital adrenal hyperplasia (CAH) resulting
Congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency
Congenital_adrenal_hyperplasia_due_to_3β-hydroxysteroid_dehydrogenase_deficiency
Class of enzymes
In enzymology, 20-α-hydroxysteroid dehydrogenase (EC 1.1.1.149) is an enzyme that catalyzes the chemical reaction 17α,20α-dihydroxypregn-4-en-3-one + NADP+
20alpha-hydroxysteroid dehydrogenase
20alpha-hydroxysteroid_dehydrogenase
Class of enzymes
\rightleftharpoons } 16beta-hydroxysteroid Hence, this enzyme has one substrate, 16alpha-hydroxysteroid, and one product, 16beta-hydroxysteroid. This enzyme belongs
16-hydroxysteroid_epimerase
Class of oxidoreductase enzymes
Hydroxysteroid dehydrogenases (HSDs) are a group of alcohol oxidoreductases that catalyze the dehydrogenation of hydroxysteroids. These enzymes also catalyze
Hydroxysteroid_dehydrogenase
Endogenous steroid hormone
addition, it can be converted back into DHT via 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing conventional intermediates
Androsterone
Enzyme
In enzymology, 21-hydroxysteroid dehydrogenase (NADP+) (EC 1.1.1.151) is an enzyme that catalyzes the chemical reaction (5β)-pregnan-21-ol + NADP+
21-hydroxysteroid dehydrogenase (NADP+)
21-hydroxysteroid_dehydrogenase_(NADP+)
Rare autosomal recessive disorder causing impaired masculinisation
17β-Hydroxysteroid dehydrogenase III deficiency is a rare autosomal recessive disorder of sexual development condition that is a cause of 46,XY disorder
17β-Hydroxysteroid dehydrogenase III deficiency
17β-Hydroxysteroid_dehydrogenase_III_deficiency
Enzyme found in humans
Corticosteroid 11-β-dehydrogenase isozyme 2 also known as 11-β-hydroxysteroid dehydrogenase 2 is an enzyme that in humans is encoded by the HSD11B2 gene
Corticosteroid 11-beta-dehydrogenase isozyme 2
Corticosteroid_11-beta-dehydrogenase_isozyme_2
Mammalian protein found in humans
11β-Hydroxysteroid dehydrogenase type 1, also known as cortisone reductase, is an NADPH-dependent enzyme highly expressed in key metabolic tissues including
11β-Hydroxysteroid dehydrogenase type 1
11β-Hydroxysteroid_dehydrogenase_type_1
Class of enzymes
17)alpha-hydroxysteroid dehydrogenase (EC 1.1.1.209, 3(17)alpha-hydroxysteroid dehydrogenase) is an enzyme with systematic name 3(or 17)alpha-hydroxysteroid:NAD(P)+
3(or 17)a-hydroxysteroid dehydrogenase
3(or_17)a-hydroxysteroid_dehydrogenase
Class of enzymes
enzymology, a 7beta-hydroxysteroid dehydrogenase (NADP+) (EC 1.1.1.201) is an enzyme that catalyzes the chemical reaction a 7beta-hydroxysteroid + NADP+ ⇌ {\displaystyle
7beta-hydroxysteroid dehydrogenase (NADP+)
7beta-hydroxysteroid_dehydrogenase_(NADP+)
steroid + AH2 + O2 ⇌ {\displaystyle \rightleftharpoons } a 17alpha-hydroxysteroid + A + H2O The 3 substrates of this enzyme are steroid, an electron acceptor
Steroid_17alpha-monooxygenase
Enzyme
In enzymology, a 3-β(or 20-α)-hydroxysteroid dehydrogenase (EC 1.1.1.210) is an enzyme that catalyzes the chemical reaction 5α-androstan-3β,17β-diol +
3beta(or 20alpha)-hydroxysteroid dehydrogenase
3beta(or_20alpha)-hydroxysteroid_dehydrogenase
Enzyme
In enzymology, 21-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.150) is an enzyme that catalyzes the chemical reaction (5β)-pregnan-21-ol + NAD+
21-hydroxysteroid dehydrogenase (NAD+)
21-hydroxysteroid_dehydrogenase_(NAD+)
Index of enzymes associated with the same name
3-Hydroxysteroid dehydrogenase (3-HSD) may refer to: 3α-Hydroxysteroid dehydrogenase (3α-HSD) 3β-Hydroxysteroid dehydrogenase (3β-HSD) This set index
3-Hydroxysteroid dehydrogenase
3-Hydroxysteroid_dehydrogenase
Protein-coding gene in the species Homo sapiens
17β-Hydroxysteroid dehydrogenase 1 (17β-HSD1) is an enzyme that in humans is encoded by the HSD17B1 gene. This enzyme oxidizes or reduces the C17 hydroxy/keto
HSD17B1
Class of enzymes
In enzymology, 7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159) is an enzyme that catalyzes the chemical reaction cholic acid + NAD+ H+ H+
7alpha-hydroxysteroid dehydrogenase
7alpha-hydroxysteroid_dehydrogenase
Class of enzymes
In enzymology, a 12beta-hydroxysteroid dehydrogenase (EC 1.1.1.238) is an enzyme that catalyzes the chemical reaction 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate
12beta-hydroxysteroid dehydrogenase
12beta-hydroxysteroid_dehydrogenase
Protein-coding gene in the species Homo sapiens
17β-Hydroxysteroid dehydrogenase 3 (17β-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis. This
HSD17B3
Medical condition
D-bifunctional protein deficiency Other names 17β-hydroxysteroid dehydrogenase IV deficiency Specialty Medical genetics
D-bifunctional protein deficiency
D-bifunctional_protein_deficiency
Enzyme
In enzymology, a 3alpha-hydroxysteroid dehydrogenase (B-specific) (EC 1.1.1.50) is an enzyme that catalyzes the chemical reaction Androsterone + NAD+
3alpha-hydroxysteroid dehydrogenase (B-specific)
3alpha-hydroxysteroid_dehydrogenase_(B-specific)
Enzyme
In enzymology, a 3alpha-hydroxysteroid dehydrogenase (A-specific) (EC 1.1.1.213) is an enzyme that catalyzes the chemical reaction androsterone + NAD(P)+
3alpha-hydroxysteroid dehydrogenase (A-specific)
3alpha-hydroxysteroid_dehydrogenase_(A-specific)
Protein-coding gene in the species Homo sapiens
17β-Hydroxysteroid dehydrogenase 2 (17β-HSD2) is an enzyme of the 17β-hydroxysteroid dehydrogenase (17β-HSD) family that in humans is encoded by the HSD17B2
HSD17B2
Enzyme
In enzymology, a 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.239) is an enzyme that catalyzes the chemical reaction: Testosterone + NAD+
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)
Class of enzymes
17beta-dehydrogenase (NADP)) is an enzyme with systematic name 17beta-hydroxysteroid:NADP+ 17-oxidoreductase. This enzyme catalyses the chemical reaction
Testosterone 17b-dehydrogenase (NADP+)
Testosterone_17b-dehydrogenase_(NADP+)
Class of enzymes
In enzymology, a 3alpha(or 20beta)-hydroxysteroid dehydrogenase (EC 1.1.1.53) is an enzyme that catalyzes the chemical reaction 3α-Androstanediol + NAD+
3alpha(or 20beta)-hydroxysteroid dehydrogenase
3alpha(or_20beta)-hydroxysteroid_dehydrogenase
Protein-coding gene in the species Homo sapiens
reductase family 1 member C2, also known as bile acid binding protein, 3α-hydroxysteroid dehydrogenase type 3 (3α-HSD3), and dihydrodiol dehydrogenase type 2
AKR1C2
Medical condition
enzymes involved in steroid metabolism, like 11β-hydroxylase or 3β-hydroxysteroid dehydrogenase. It has a prevalence between 0.1% and 2% depending on
Late onset congenital adrenal hyperplasia
Late_onset_congenital_adrenal_hyperplasia
Protein-coding gene in the species Homo sapiens
member C3 (AKR1C3), also known as 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5, HSD17B5) or 3α-hydroxysteroid dehydrogenase type 2 (3α-HSD2) is a steroidogenic
AKR1C3
Protein-coding gene in the species Homo sapiens
as peroxisomal multifunctional enzyme type 2 (MFP-2), as well as 17β-hydroxysteroid dehydrogenase type IV (17β-HSD type IV) is a protein that in humans
HSD17B4
Type of enzyme
P450 (CYP1, 2, 3) – estrogen metabolism Hydroxysteroid dehydrogenases (and ketosteroid reductases) 3α-Hydroxysteroid dehydrogenase – androgen, progestogen
Steroidogenic_enzyme
Chemical compound
Etiocholanolone 17-Ketosteroids are endogenous steroid hormones. Hydroxysteroid Hydroxysteroid dehydrogenase 17-Ketosteroids at the U.S. National Library of
Ketosteroid
Corticosteroid precursor and metabolite of cortisol
actions of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1). Cortisol can also be metabolized back into cortisone by the actions of 11β-hydroxysteroid dehydrogenase
Cortisone
Family of aldo-keto reductase enzymes
3α-HSDTooltip 3α-Hydroxysteroid dehydrogenases, 3β-HSDsTooltip 3β-Hydroxysteroid dehydrogenases, 5β-reductases, 11β-HSDsTooltip 11β-Hydroxysteroid dehydrogenases
AKR1
Vertebrate natural glucocorticoid hormone
enzyme). Cortisol is metabolized reversibly to cortisone by the 11-beta hydroxysteroid dehydrogenase system (11-beta HSD), which consists of two enzymes: 11-beta
Cortisol
Medical condition
mutations in the HSD11B2 gene, which encodes the kidney isozyme of 11β-hydroxysteroid dehydrogenase type 2. In an unaffected individual, this isozyme inactivates
Apparent mineralocorticoid excess syndrome
Apparent_mineralocorticoid_excess_syndrome
as acceptors. The systematic name for this enzyme class is 17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase. Commonly used names include 17alpha-estradiol
Estradiol 17alpha-dehydrogenase
Estradiol_17alpha-dehydrogenase
17-oxidoreductase. Other names in common use include 20alpha-hydroxysteroid dehydrogenase, 17beta,20alpha-hydroxysteroid dehydrogenase, 17beta-estradiol dehydrogenase
Estradiol 17beta-dehydrogenase
Estradiol_17beta-dehydrogenase
Chemical compound
natural steroids androstanediol via 17β-hydroxysteroid dehydrogenase or from androstanedione via 3β-hydroxysteroid dehydrogenase. Epiandrosterone is used
Epiandrosterone
Enzyme
that catalyzes the reduction of keto sterols to the corresponding 3β-hydroxysteroids. For example: lophenol + NADP+ H+ H+ 4α-methyllathosterone
3-Ketosteroid_reductase
Protein-coding gene in the species Homo sapiens
HSD3B2 is a human gene that encodes for 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type II or hydroxy-delta-5-steroid dehydrogenase
HSD3B2
Protein-coding gene in the species Homo sapiens
HSD3B1 is a human gene that encodes for a 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type I or hydroxy-delta-5-steroid dehydrogenase
HSD3B1
Protein-coding gene in the species Homo sapiens
Aldo-keto reductase family 1 member C1 also known as 20α-hydroxysteroid dehydrogenase, 3α-hydroxysteroid dehydrogenase, and dihydrodiol dehydrogenase 1/2 is
AKR1C1
Protein-coding gene in the species Homo sapiens
17β-Hydroxysteroid dehydrogenase type 13 also known as 17β-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene. 17β-HSD13 is significantly
HSD17B13
Protein-coding gene in the species Homo sapiens
Aldo-keto reductase family 1 member C4, also known as 3α-Hydroxysteroid dehydrogenase type 1 (3α-HSD1), is an enzyme that in humans is encoded by the AKR1C4
AKR1C4
Chemical compound
is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic
Drostanolone_propionate
Enzyme
3-oxidoreductase. Other names in common use include 3beta-hydroxysteroid 5beta-oxidoreductase, and 3beta-hydroxysteroid 5beta-progesterone oxidoreductase. Enzyme 1
3beta-hydroxy-5beta-steroid dehydrogenase
3beta-hydroxy-5beta-steroid_dehydrogenase
Class of enzymes
The enzyme 5α-hydroxysteroid dehydratase (EC 4.2.1.62) catalyzes the chemical reaction 5α-ergosta-7,22-diene-3β,5-diol ⇌ {\displaystyle \rightleftharpoons
5alpha-hydroxysteroid dehydratase
5alpha-hydroxysteroid_dehydratase
Protein-coding gene in the species Homo sapiens
an enzyme that in humans is encoded by the HSD17B7 gene. The 17-beta-hydroxysteroid dehydrogenase enzyme (EC 1.1.1.62) oxidizes or reduces estrogens and
HSD17B7
Chemical compound
subsequently claimed by AstraZeneca as an inhibitor of the enzyme 11β-Hydroxysteroid dehydrogenase type 1. No other pharmacological data has been disclosed
2-(Ethylamino)-1,2-diphenylethanone
2-(Ethylamino)-1,2-diphenylethanone
Protein-coding gene in the species Homo sapiens
17-β-Hydroxysteroid dehydrogenase X (HSD10) also known as 3-hydroxyacyl-CoA dehydrogenase type-2 is a mitochondrial enzyme that in humans is encoded by
HSD17B10
Class of steroids
C24 Cholane Bile acid C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements
Norsteroid
Enzyme
In enzymology, a sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) is an enzyme that catalyzes the chemical reaction 3beta-hy
Sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
Sterol-4alpha-carboxylate_3-dehydrogenase_(decarboxylating)
Chemical compound
activities in humans. The compound is synthesized from androstadienol by 3β-hydroxysteroid dehydrogenase, and can be converted into androstenone (a more potent
Androstadienone
Class of chemicals derived from steroids
C24 Cholane Bile acid C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements
Secosteroid
Hydroxysteroid 17-beta dehydrogenase 6 is an enzyme that in humans is encoded by the HSD17B6 gene. The protein encoded by this gene has both oxidoreductase
HSD17B6
Chemical compound
is formed from androstenedione by 5α-reductase and from DHT by 17β-hydroxysteroid dehydrogenase. It has some androgenic activity. In female genital skin
Androstanedione
Genetic disorders of the adrenal gland
result in an apparent vulva. Ambiguous genitalia in XY males with 3β-hydroxysteroid dehydrogenase deficiency (3β-HSD2D). In females, hypogonadism can cause
Congenital adrenal hyperplasia
Congenital_adrenal_hyperplasia
NADP+ as acceptor. The systematic name of this enzyme class is 17beta-hydroxysteroid:NAD+ 17-oxidoreductase. Other names in common use include 17-ketoreductase
Testosterone 17beta-dehydrogenase
Testosterone_17beta-dehydrogenase
Protein-coding gene in the species Homo sapiens
encoded by the HSD17B8 gene. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active
HSD17B8
Protein-coding gene in the species Homo sapiens
17β-Hydroxysteroid dehydrogenase type 14 also known as 17β-HSD type 14 or 17βHSD14 is an enzyme that in humans is encoded by the HSD17B14 gene. 17βHSD14
HSD17B14
Chemical compound
monooxygenases, mainly, 6β-hydroxysteroid dehydrogenase (CYP3A4). 6β-hydroxycortisol is used as a biomarker of 6β-hydroxysteroid dehydrogenase (CYP3A4) activity
6β-Hydroxycortisol
Chemical compound
in axillary odor. It is produced from androstenone via the enzyme 3β-hydroxysteroid dehydrogenase. Unlike its C3α epimer 3α-androstenol, 3β-androstenol
3β-Androstenol
Drug class
20-lyase inhibitors): inhibit the synthesis of androgens from pregnanes 3β-Hydroxysteroid dehydrogenase inhibitors (3β-HSD inhibitors): inhibit the conversion
Androgen_synthesis_inhibitor
Chemical compound
addition, metribolone was identified in 2010 as a potent inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD) 1 and 2 (IC50 = 0.02 and 0.16 μM, respectively)
Metribolone
Compounds that alter neuronal activity
3α-hydroxysteroid dehydrogenase are involved in the biosynthesis of inhibitory neurosteroids, while 3β-hydroxysteroid dehydrogenase and hydroxysteroid sulfotransferases
Neurosteroid
Chemical compound
inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD). As a result of this action, trilostane blocks the conversion of Δ5-3β-hydroxysteroids, including pregnenolone
Trilostane
Chemical compound
(respectively) similarly) are known to be potent inhibitors of 11β-hydroxysteroid dehydrogenase (11β-HSD), which is responsible for the biosynthesis of
Formebolone
Catechin (polyphenol) in tea
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is the ester of epigallocatechin and gallic acid, and is a type of catechin
Epigallocatechin_gallate
Anti-inflammatory drug
Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain
Indometacin
Chemical compound
C24 Cholane Bile acid C27 Cholestane Functional group 17-Ketosteroid Hydroxysteroid Halogenated steroid Elements removed Norsteroid Secosteroid Elements
Estrin_(molecule)
Chemical compound
very potent competitive inhibitor of both isoforms (1 and 2) of 11β-hydroxysteroid dehydrogenase (11β-HSD). It is notably not metabolized by 11β-HSD2.
11α-Hydroxyprogesterone
Substance that quells or blunts the libido
Studies have demonstrated that some of these products inhibit 17β-hydroxysteroid dehydrogenase and 17,20-lyase, which catalyzes the conversion of
Anaphrodisiac
Gonadotropin secreted by the adenohypophysis
to androstenedione by 3β-hydroxysteroid dehydrogenase (3β-HSD) and then finally converted to testosterone by 17β-hydroxysteroid dehydrogenase (HSD17B).
Luteinizing_hormone
Enzyme
adrenal ferredoxin + O2 ⇌ {\displaystyle \rightleftharpoons } an 11beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O The 3 substrates of this enzyme
Steroid_11beta-monooxygenase
Medication mainly used for depression and smoking cessation
CYP2C19 leading to 4'-hydroxybupropion. The reductive pathways are by 11β-hydroxysteroid dehydrogenase type 1 in the liver and AKR7A2/AKR7A3 in the intestine
Bupropion
Protein-coding gene in humans
open reading frame 54, also known as HSD-29 (hydroxysteroid 29 dehydrogenase) and HSD-30 (hydroxysteroid 30 dehydrogenase) is a protein coding gene. The
C12orf54
Class of medications
the skin of reductive 17β-hydroxysteroid dehydrogenase, and oxidative 3α-hydroxysteroid dehydrogenase and 3β-hydroxysteroid dehydrogenase enzymes. In
5α-Reductase_inhibitor
Chemical compound
16-ene-synthetase activity of CYP17A1, and is converted into androstadienone by 3β-hydroxysteroid dehydrogenase. Male sweat contains approximately five times as much
Androstadienol
Chemical compound
glucocorticosteroids and androstenedione through the activity of 3α-hydroxysteroid dehydrogenase. Measurements of 17α-hydroxypregnenolone are useful in
17α-Hydroxypregnenolone
Chemical compound
by 3β-hydroxysteroid dehydrogenase type I into androstenedione, and androstenedione is aromatized into estrone. Then, placental 17β-hydroxysteroid dehydrogenase
Estriol
Enzyme
Kaplan NO (1969). "Purification and substrate specificities of bacterial hydroxysteroid dehydrogenases". Biochemistry. 8 (12): 5093–103. doi:10.1021/bi00840a063
3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase
3alpha-hydroxy-5beta-androstane-17-one_3alpha-dehydrogenase
Main sweet-tasting constituent of liquorice
Glycyrrhizin (glycyrrhizic acid or glycyrrhizinic acid) is the chief sweet-tasting constituent of Glycyrrhiza glabra (liquorice) root. Structurally, it
Glycyrrhizin
Medical condition
other causes such as partial androgen insensitivity syndrome and 17β-hydroxysteroid dehydrogenase 3 deficiency. Hair on the face and body is reduced and
5α-Reductase_2_deficiency
Chemical compound
Fluoxymesterone has been found to act as a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) (IC50Tooltip Half-maximal inhibitory
Fluoxymesterone
Protein-coding gene in the species Homo sapiens
that in humans is encoded by the HSD17B12 gene. The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA
HSD17B12
Female adult human
change in 46,XY persons with 5alpha-reductase-2 deficiency and 17beta-hydroxysteroid dehydrogenase-3 deficiency". Archives of Sexual Behavior. 34 (4): 399–410
Woman
Class of chemical compounds
tissues have all of the enzymes, including 3β-hydroxysteroid dehydrogenase (3β-HSD), 17β-hydroxysteroid dehydrogenase (17β-HSD), 5α-reductase, and steroid
Adrenal_steroid
Human hormone
prostate gland. In addition, unlike testosterone, DHT is inactivated by 3α-hydroxysteroid dehydrogenase (3α-HSD) into the very weak androgen 3α-androstanediol
Dihydrotestosterone
Chemical compound
inhibits the conversion of inactive cortisone to cortisol by blocking 11β-hydroxysteroid dehydrogenase (11β-HSD). 11β-HSD also reversibly catalyzes the conversion
Carbenoxolone
Abnormally high tissue pH due to metabolic dysfunction
Hypertension-associated Primary aldosteronism Nasogastric suction 11β-hydroxysteroid dehydrogenase type 2 deficiency Congenital chloride diarrhea Liquorice
Metabolic_alkalosis
steroid hormones by the action of two enzymes, 5α-reductase and 3α-hydroxysteroid dehydrogenase (3α-HSD). These enzymes can be inhibited by 5α-reductase
Neurosteroidogenesis inhibitor
Neurosteroidogenesis_inhibitor
Chemical compound
5α-DHF can be further metabolized into 3α,5α-tetrahydrocortisol by 3α-hydroxysteroid dehydrogenase. "Hydrallostane". Azzouni F, Godoy A, Li Y, Mohler J (2012)
5α-Dihydrocortisol
HYDROXYSTEROID
HYDROXYSTEROID
HYDROXYSTEROID
HYDROXYSTEROID
Boy/Male
American, German
Happiness; Joy
Surname or Lastname
English (Lancashire and Yorkshire)
English (Lancashire and Yorkshire) : habitational name from a place in Lancashire now known as Oakenbottom. The history of the place name is somewhat confused, but it is probably composed of the Old English elements Ç£cen or Äcen ‘oaken’ + botme ‘broad valley’. During the Middle Ages this name became successively Eakenbottom and Ickenbottom, the first element becoming associated with the dialect word hicken or higgen ‘mountain ash’ or the personal name Higgin.
Boy/Male
American, Anglo, Australian, British, Christian, English, French, German, Gujarati, Hindu, Indian
Mighty with a Spear; Spear; Form of Garret; To Watch
Girl/Female
Indian
Successful, Prosperous
Girl/Female
Biblical
Going out, departure.
Boy/Male
Hindu
(Son of Kesari)
Boy/Male
Arabic, Muslim
Respected; Accountant; Avenger; Another Name for Prophet Muhammad; Noble
Girl/Female
Dutch, German, Swedish
Lady
Girl/Female
Tamil
Kunshita | கà¯à®¨à¯à®·à¯€à®¤à®¾Â
Reference to the immaculate conception
Boy/Male
German American English
Powerful ruler.
HYDROXYSTEROID
HYDROXYSTEROID
HYDROXYSTEROID
HYDROXYSTEROID
HYDROXYSTEROID