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A neurosteroidogenesis inhibitor is a drug that inhibits the production of endogenous neurosteroids. Neurosteroids include the excitatory neurosteroids
Neurosteroidogenesis inhibitor
Neurosteroidogenesis_inhibitor
Class of medications
List of 5α-reductase inhibitors Discovery and development of 5α-reductase inhibitors CYP17A1 inhibitor Neurosteroidogenesis inhibitor Ulrike Blume-Peytavi;
5α-Reductase_inhibitor
Drug class
A steroidogenesis inhibitor, also known as a steroid biosynthesis inhibitor, is a type of drug which inhibits one or more of the enzymes that are involved
Steroidogenesis_inhibitor
Antiandrogen medication
prevents the formation of neurosteroids, it functions as a neurosteroidogenesis inhibitor and may contribute to a reduction of GABAA activity. Reduction
Finasteride
Compounds that alter neuronal activity
benzodiazepines may also inhibit neurosteroidogenic enzymes reducing neurosteroid synthesis. List of neurosteroids Neurosteroidogenesis inhibitor Membrane steroid
Neurosteroid
Drug
Progonadotropin CYP17A1 inhibitor Steroidogenesis inhibitor Antiandrogen Antiestrogen Antiprogestogen Neurosteroidogenesis inhibitor Jonathan S. Berek; Emil
Antigonadotropin
Antiandrogen and hormone replacement medication
inhibition of DHT production, 5α-reductase inhibitors such as dutasteride are also neurosteroidogenesis inhibitors, preventing the 5α-reductase-mediated biosynthesis
Dutasteride
Protein-coding gene in the species Homo sapiens
Costa E, Auta J, Guidotti A, et al. (1994). "The pharmacology of neurosteroidogenesis". J. Steroid Biochem. Mol. Biol. 49 (4–6): 385–389. doi:10
Diazepam_binding_inhibitor
for the treatment of alcoholism in the 1950s List of steroids Neurosteroidogenesis inhibitor Linsenbardt AJ, Taylor A, Emnett CM, Doherty JJ, Krishnan K
List_of_neurosteroids
Human protein
for both rat and human forms of TSPO. Steroidogenic enzyme Neurosteroidogenesis inhibitor GRCh38: Ensembl release 89: ENSG00000100300 – Ensembl, May 2017
Translocator_protein
List of pharmaceutical drugs under clinical development for treatment of depression
(GlyT1) inhibitor Solriamfetol (Sunosi; JZP-110; SKLN05; ARL-N05; YKP-10A; R-228060; ADX-N05) – norepinephrine and dopamine reuptake inhibitor and trace
List of investigational antidepressants
List_of_investigational_antidepressants
Chemical compound
Guidotti A, Korneyev A, Romeo E (June 1994). "The pharmacology of neurosteroidogenesis". The Journal of Steroid Biochemistry and Molecular Biology. 49 (4–6):
FGIN-143
Guidotti, A.; Korneyev, A.; Romeo, E. (June 1994). "The pharmacology of neurosteroidogenesis". The Journal of Steroid Biochemistry and Molecular Biology. 49 (4–6):
Vassilios_Papadopoulos
Anxiolytic medication
anxiolytic effects of alpidem. This protein mediates promotion of neurosteroidogenesis in the brain, for instance of allopregnanolone. Alpidem is structurally
Alpidem
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NEUROSTEROIDOGENESIS INHIBITOR
NEUROSTEROIDOGENESIS INHIBITOR
NEUROSTEROIDOGENESIS INHIBITOR
NEUROSTEROIDOGENESIS INHIBITOR
NEUROSTEROIDOGENESIS INHIBITOR
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