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Biotechnology company
ImmunoGen, Inc. was a biotechnology company focused on the development of antibody-drug conjugate (ADC) therapeutics for the treatment of cancer. ImmunoGen
ImmunoGen
Antigen/epitope that induce immune response
An immunogen is any substance that generates B-cell (humoral/antibody) and/or T-cell (cellular) adaptive immune responses upon exposure to a host organism
Immunogen
Topics referred to by the same term
Immunogen may refer to: ImmunoGen, a pharmaceuticals company Immunogen, an antigen/epitope inducing an immune response This disambiguation page lists articles
Immunogen_(disambiguation)
American pharmaceutical company
facing competition from biosimilars. In February 2024, AbbVie acquired ImmunoGen for $10.1 billion, aiming to expedite its entry into the ovarian cancer
AbbVie
Molecule triggering an immune response
correct. All immunogens are antigens, but not all antigens are immunogens. The antigen within a vaccine is often referred to as an immunogen, even if, strictly
Antigen
Species of bacterium
Mycobacteroides immunogenum (formerly Mycobacterium immunogenum) is a species of bacteria from the phylum Actinomycetota, belonging to the genus Mycobacteroides
Mycobacteroides_immunogenum
Outermost layer of many types of the infectious agent
(2018-03-08). "Common Features of Enveloped Viruses and Implications for Immunogen Design for Next-Generation Vaccines". Cell. 172 (6): 1319–1334. doi:10
Viral_envelope
Reaction between an antibody and an antigen that differs from the immunogen
the reaction between an antibody and an antigen that differs from the immunogen. It is sometimes also referred to as cross-immunity or cross-protective
Cross-reactivity
Ingredients used in a vaccine dose
and preservatives) very little of which is the active ingredient, the immunogen. A single dose may have merely nanograms of virus particles, or micrograms
Vaccine_ingredients
Ability of a foreign substance to provoke an immune response
response, it is an 'immunogenic antigen', which is referred to as an immunogen. Many lipids and nucleic acids are relatively small molecules and/or have
Immunogenicity
American private equity firm
investments of the 1970s were Biogen, Artificial Intelligence Software, Immunogen and Digital Research. Jacqui Morby, one of the first women to become a
TA_Associates
Chemical compound
according to the WHO. DM1 and its attachment via these linkers result from ImmunoGen Inc research. An example is: Trastuzumab emtansine (T-DM1), an anti-HER2/neu
Mertansine
Class of pharmaceutical drugs
adrenocorticotropic hormone (ACTH)-induced production of adrenal androgens; and immunogens and vaccines against androstenedione like ovandrotone albumin and androstenedione
Antiandrogen
Process strengthening the immune system
immune system becomes fortified against an infectious agent (known as the immunogen). When this system is exposed to molecules that are foreign to the body
Immunization
Chemical compound
Biotechnology News. ImmunoGen reports encouraging clinical data of IMGN901. News-medical.net. Retrieved on 2010-11-20. "ImmunoGen receives FDA orphan
Lorvotuzumab_mertansine
Vaccine
Androvax, also known as androstenedione:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine
Androvax
Protein found in humans
of neurological pathologies, most notably, multiple sclerosis, as an immunogen. Syncytin-1 mediated trophoblast fusion is essential for normal placental
Syncytin-1
Beam anchored at only one end
based on an antibody layer that interacts selectively with a particular immunogen. In the static mode of operation, the sensor response is represented by
Cantilever
Vaccine containing DNA
interest) are sometimes constructed to express more than one immunogen, or to express an immunogen and an immunostimulatory protein. Because the plasmid –
DNA_vaccine
Hemagglutinin of influenza virus
away from the receptor binding site. In 2015 researchers designed an immunogen mimicking the HA stem, specifically the area where the antibody ties to
Hemagglutinin_(influenza)
American inventor of the polio vaccine (1914–1995)
from the original on April 1, 2017. Retrieved May 4, 2017. Remune (HIV-1 Immunogen, Salk vaccine) Archived March 21, 2009, at the Wayback Machine AIDSmeds
Jonas_Salk
Systematic naming of drugs
Approach. Medicus Media. p. 2371. ISBN 0803613245. "Antibody Production (Immunogen Preparation)". www.piercenet.com. Retrieved 2013-10-17.{{cite web}}: CS1
Drug_nomenclature
Administration of a vaccine to protect against disease
disease. The activation occurs through priming the immune system with an immunogen. Stimulating immune responses with an infectious agent is known as immunization
Vaccination
Human retrovirus, cause of AIDS
J (1998). "The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens". Science. 280 (5371): 1884–8. Bibcode:1998Sci...280.1884W. doi:10.1126/science
HIV
Method for clinical diagnosis, treatment, and biological research of proteins
and roasted walnuts can be utilized as immunogens. Protein concentrations of the defatted powdered immunogens are set through the Kjeldahl method with
Protein_detection
American physician and immunologist
In 2012, Haynes was awarded a Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery (CHAVI-ID) to continue HIV vaccine development. From 2012-2019
Barton_Haynes
American physician and virologist (born 1932)
"Scientific Advisory Board". Duke Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery. Archived from the original on 2015-08-03. Retrieved 14 Aug
Stanley_Plotkin
the sporozoite (SPZ) stage of the malaria parasite, Plasmodium, as an immunogen, and as a carrier for immunomodulatory molecules. Sanaria's primary mission
Sanaria
Human Genome Sciences (1992–2012) IL (????–2006; acquired by Pacgen) ImmunoGen (1981–2024) Immunomedics (1982–2020) Indian Drugs and Pharmaceuticals
List of pharmaceutical companies
List_of_pharmaceutical_companies
Hormone therapy used to treat symptoms of menopause
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Hormone_replacement_therapy
Nonprofit American medical research institute
com. Retrieved 2018-02-13. "Center for HIV/AIDS Vaccine Immunology & Immunogen Discovery". scripps.edu. "2011 Sep/Oct – Chemistry, At the Highest Level"
Scripps_Research
American cell biologist and micrographer
she co-discovered the vault (organelle). Subsequently, she worked at ImmunoGen Inc. where she worked on staining and photographing different cancer cells
Nancy_Kedersha
Class of biopharmaceutical drugs
progression on or after chemotherapy Mirvetuximab soravtansine Elahere ImmunoGen treatment of adults with folate receptor alpha (FRα)-positive, platinum-resistant
Antibody–drug_conjugate
Species of bacterium
2018). "Mannheimia haemolytica in bovine respiratory disease: immunogens, potential immunogens, and vaccines". Animal Health Research Reviews. 19 (2): 79–99
Mannheimia_haemolytica
which the same immunogen is used repeatedly for vaccination, the sequential immunization approach relies on a series of different immunogens with the goal
Management_of_HIV/AIDS
Preparation for acquired immunity to disease
and preservatives) very little of which is the active ingredient, the immunogen. A single dose may have merely nanograms of virus particles, or micrograms
Vaccine
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
List of 5α-reductase inhibitors
List_of_5α-reductase_inhibitors
Gender-affirming medical treatment
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Gender-affirming hormone therapy
Gender-affirming_hormone_therapy
Any steroid hormone that promotes male characteristics
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Androgen
Anabolic steroid
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Nandrolone_phenylpropionate
Form of hormone therapy
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Androgen_replacement_therapy
Androgen and anabolic steroid
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Oxandrolone
American private equity investor
billion acquisition of Catalent, AbbVie's $10.1 billion acquisition of ImmunoGen, and Uber's $2.25 billion acquisition of Transplace. Madu then joined
Kristofer_Madu
Antiandrogen medication
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Finasteride
Type of toxic lectin
RiVax, RTA1-33/44-198, and a single domain antibody-antigen complex with the RTA1-33/44-198 immunogen. Original figure can be found in Legler, et al.
Ricin
Steroidal antiandrogen and antimineralocorticoid
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Spironolactone
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Dehydroepiandrosterone
Class of pharmaceutical drugs
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Selective androgen receptor modulator
Selective_androgen_receptor_modulator
Primary female sex hormone
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Estrogen
Type of hormone replacement therapy with unclear efficacy
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Bioidentical hormone replacement therapy
Bioidentical_hormone_replacement_therapy
Chemical compound
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Estradiol_valerate
Protein type
immature laminin receptor protein are identical, universal T-cell inducing immunogens on primary rodent and human cancers. Anticancer Res. 1999 Nov-Dec;19(6C):5535-42
Oncofetal_antigen
Anabolic steroid
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Nandrolone_decanoate
Androgenic Anabolic steroid
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Nandrolone
Hormonal treatment for prostate cancer
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Androgen_deprivation_therapy
Species of virus
H261L enhance the stability of this form, making it a more effective immunogen. This approach aims to develop vaccines that are both more cost-effective
Rabies_virus
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Testosterone_enanthate
Type of antibody
not a heterophile antibody? When it is an antibody against a specific immunogen". Clinical Chemistry. 45 (5): 616–618. doi:10.1093/clinchem/45.5.616.
Heterophile_antibody
Commercial production of peptides
development of binding assays, the study of receptor agonist/antagonists or as immunogens for the production of specific antibodies. Generally, peptides are synthesized
Custom_peptide_synthesis
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Drostanolone_propionate
Primary male sex hormone
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Testosterone
Type of gender-affirming medical treatment
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Feminizing_hormone_therapy
Vaccine to prevent poliomyelitis
generic sense, vaccination works by priming the immune system with an "immunogen". Stimulating immune response, by use of an infectious agent, is known
Polio_vaccine
Androgen and anabolic steroid
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Oxymetholone
Breast cancer drug
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Letrozole
Hormone replacement medication
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Dutasteride
Indian biophysicist and professor (b. 1960)
IISc which has research interests in the design of HIV-1 and influenza immunogens. He also serves as an honorary professor at Jawaharlal Nehru Centre for
Raghavan_Varadarajan
American multinational law firm
Union Bank HPS Corporate Lending Fund's 2025 $1.1 billion bond offering ImmunoGen advisement in its 2023 $10.1 billion acquisition by Abbvie Inc. TPG advisement
Ropes_&_Gray
Accidental puncture of skin causing contamination
J (1998). "The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens". Science. 280 (5371): 1884–88. Bibcode:1998Sci...280.1884W. doi:10.1126/science
Needlestick_injury
Anabolic steroid
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Trenbolone
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Testosterone_cypionate
Class of drugs
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Aromatase_inhibitor
Vaccine that contains antigenic parts of the pathogen
B cell receptor signalling pathway. After dendritic cells capture the immunogen present in the vaccine, they can present the substances to naive B cells
Subunit_vaccine
Method of administering medication
immune tolerance mechanisms that prevent the body from overreacting to immunogens encountered in the course of daily life. Buccal tablets are a type of
Buccal_administration
Human hormone
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Dihydrotestosterone
Antiandrogen medication used in treatment of prostate cancer
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Enzalutamide
Androgen and anabolic steroid
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Metandienone
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Mesterolone
Protein-coding gene in the species Homo sapiens
sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. GRCh38: Ensembl release 89: ENSG00000134940 – Ensembl, May
ACRV1
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Boldenone_undecylenate
Medical treatment for venomous bites and stings
several processes and may contain other serum proteins that can act as immunogens. Some individuals may react to the antivenom with an immediate hypersensitivity
Antivenom
Immunogen and vaccine against androstenedione
polyandroalbumin, as well as ovandrotone:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine
Ovandrotone_albumin
Pharmaceutical drug classification
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
ATC_code_A
Pharmaceutical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Deuterated_testosterone
Antiandrogen with a nonsteroidal chemical structure
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Nonsteroidal_antiandrogen
Selective estrogen receptor modulator
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Tamoxifen
Genomics services company
(August 8, 2014). "In silico prediction of Gallibacterium anatis pan-immunogens". Veterinary Research. 45 (1): 80. doi:10.1186/s13567-014-0080-0. PMC 4423631
CD_Genomics
Species of tick
60: 65. Stone BF & Binnington KC (1986) The paralyzing toxin and other immunogens of the tick I. holocyclus and the role of the salivary gland in their
Ixodes_holocyclus
Class of drugs
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Anabolic_steroid
Biomolecule
ASPsiRNA resource.[non-primary source needed] Plain RNAs may be poor immunogens, but antibodies can easily be created against RNA-protein complexes. Many
Small_interfering_RNA
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Cyproterone_acetate
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Metenolone_enanthate
Androgenic and anabolic steroid medication
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Androstanolone
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Steroidal_aromatase_inhibitor
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Drostanolone
Steroidal hormone medication
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Estradiol_(medication)
Breast cancer medication
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Exemestane
Chemical compound
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Chlorodehydromethyltestosterone
Chlorodehydromethyltestosterone
Chemical compound
Others Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Stilbestrol
Steroid use
medroxyprogesterone acetate, megestrol acetate) Others Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin) #WHO-EM
Ergogenic use of anabolic steroids
Ergogenic_use_of_anabolic_steroids
IMMUNOGEN
IMMUNOGEN
IMMUNOGEN
IMMUNOGEN
Boy/Male
French
German.
Female
Norse
Old Norse name composed of the elements bjorg "help, salvation" and hildr "battle, fight," hence "helpful battle maid." In mythology, this is the name of the goddess of the evening mist who slays the sun every night.Â
Girl/Female
Indian, Telugu
Goddess
Boy/Male
Arabic, Muslim
Noble Person of the Religion
Boy/Male
Hindu
Reviver of lakshmanas life
Boy/Male
Celebrity, Gujarati, Hindu, Indian, Kannada, Kashmiri, Malayalam, Marathi, Oriya, Punjabi, Sikh, Tamil, Telugu, Traditional
God Gift; Life Giving; Full of Life
Male
English
English surname transferred to forename use, derived from the name of a county of Scotland, which took its name from Gaelic Aonghus (supposedly from Aongus Fer), ANGUS means "excellent valor."Â
Girl/Female
Tamil
Leelavati | லீலாவதீ
Playful, Goddess Durga
Boy/Male
American, Australian, Hebrew
God is My Judge
Boy/Male
Indian, Sanskrit
Part of Lotus
IMMUNOGEN
IMMUNOGEN
IMMUNOGEN
IMMUNOGEN
IMMUNOGEN
n.
A substance added to an immunogenic agent to enhance the production of antibodies.