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Abnormal accumulation of iron in the body
Iron overload is the abnormal and increased accumulation of total iron in the body, leading to organ damage. The primary mechanism of organ damage is oxidative
Iron_overload
Genetic condition involving iron buildup
primary storage area for iron and naturally accumulates excess iron over time, it is likely to be damaged by iron overload. Toxins may accumulate in
Hereditary_haemochromatosis
Iron overload disorder caused by consumption of home-brewed beer
African iron overload is an iron overload disorder first observed among people of African descent in Southern Africa and Central Africa. It is now recognized
African_iron_overload
Medical condition, an iron metabolism disease
Hemosiderosis is a form of iron overload disorder resulting in the accumulation of hemosiderin. Types include: Transfusion hemosiderosis Idiopathic pulmonary
Hemosiderosis
Iron metabolism in the body
diseases of iron overload, such as hereditary hemochromatosis, and iron deficiency, such as iron-deficiency anemia. A 2024 review examined iron metabolism
Human_iron_metabolism
Mammalian protein found in Homo sapiens
deletion also had increased duodenal iron absorption, elevated plasma iron and transferrin saturation levels, and iron overload, mainly in hepatocytes. Mice have
HFE_(gene)
Medical condition
removes iron from the blood. This involves delivering iron chelating agents such as deferoxamine, deferiprone or deferasirox. If iron overload has caused
Transfusion_hemosiderosis
Diverse collection of blood-related cancers
secondary hemochromatosis due to iron overload from repeated transfusions. Patients with chronic iron overload can have iron deposits in their liver, heart
Myelodysplastic_syndrome
Chemical element with atomic number 26 (Fe)
chemotherapy may develop iron deficiency and anemia, for which intravenous iron therapy is used to restore iron levels. Iron overload, which may occur from
Iron
Cookware valued for heat retention properties
iron fish, a small iron ingot used during cooking to provide dietary iron to those with iron deficiency. People with hemochromatosis (iron overload,
Cast-iron_cookware
Medical procedure to remove heavy metals from the body
Nurchi, Valeria M.; Lachowicz, Joanna (2019). "Chapter 3. Iron Chelation for Iron Overload in Thalassemia". In Sigel, Astrid; Freisinger, Eva; Sigel,
Chelation_therapy
Anemia which requires regular blood transfusion
dependence is iron overloading, which can damage the liver, heart, bone tissue and endocrine glands. Iron chelation therapy is used to treat iron overload and common
Transfusion-dependent_anemia
Iron-carrying protein
total amount of iron stored in the body; hence, serum ferritin is used as a diagnostic test for iron-deficiency anemia and iron overload. Aggregated ferritin
Ferritin
Inherited blood disorder causing anemia
and include anemia, pallor, tiredness, enlargement of the spleen, iron overload, abnormal bone structure, jaundice, and gallstones. In severe cases
Alpha-thalassemia
Medical lab value of bound serum iron
saturation is a common indicator of iron deficiency anemia whereas a high transferrin saturation may indicate iron overload or hemochromatosis. Transferrin
Transferrin_saturation
Medical condition
Hemochromatosis type 4 is a hereditary iron overload disorder that affects ferroportin, an iron transport protein needed to export iron from cells into circulation
Hemochromatosis_type_4
Hereditary blood disorder causing anemia
ineffective production of red blood cells, increased hemolysis, and iron overload. Diagnosis is by checking the medical history of near relatives, microscopic
Beta_thalassemia
Family of inherited blood disorders
transfusion in case of an anemia crisis. Complications of transfusion include iron overload with resulting heart or liver disease. Other symptoms of thalassemias
Thalassemia
Chronic disease of the liver, characterized by fibrosis
transferrin saturation: markers of iron overload as in hemochromatosis, copper and ceruloplasmin: markers of copper overload as in Wilson's disease Immunoglobulin
Cirrhosis
Topics referred to by the same term
Look up overload or overloaded in Wiktionary, the free dictionary. Overload or overloaded may refer to: Overload (novel), a 1979 novel by Arthur Hailey
Overload
Iron formulation used to prevent or treat iron deficiency anemia
Other side effects, which may occur with excessive use, include iron overload and iron toxicity. Ferrous salts used as supplements by mouth include ferrous
Iron_supplement
Oral iron chelator
brand name Exjade among others, is an oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood
Deferasirox
Fungal infection
diabetic ketoacidosis, low white blood cells, cancer, organ transplant, iron overload, kidney problems, long-term steroids or use of immunosuppressants, and
Mucormycosis
Protein-coding gene in the species Homo sapiens
serum iron being available for developing red blood cells. When the hepcidin level is abnormally low, such as in hemochromatosis, iron overload occurs
Hepcidin
Medical condition
retardation, aminoaciduria (amino acids in the urine), cholestasis, iron overload, lactic acidosis and early death. Prior to birth, the growth of the
GRACILE_syndrome
Iron chelator
Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major. It was first approved and indicated
Deferiprone
South African geneticist (born 1975)
Stellenbosch University, where she conducted influential research into iron overload. She is now the managing director of Gene Diagnostics, a private genetic
Monique_Zaahl
Inflammation of abdominal organ lining
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Peritonitis
Inability of the liver to perform its normal functions
hepatitis B or C, autoimmune, hereditary and metabolic causes (such as iron or copper overload, steatohepatitis or non-alcoholic fatty liver disease). Acute-on-chronic
Liver_failure
cases of iron overload. The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. Iron export
Iron_in_biology
Medical condition
an inability to control how much iron is absorbed by the body, in turn leading to iron overload, where excess iron accumulates in many areas of the body
Juvenile_hemochromatosis
Chronic inflammation and degradation of the stomach lining
possibly leading to vitamin B12 deficiency; and malabsorption of iron, leading to iron deficiency anaemia. It can be caused by persistent infection with
Atrophic_gastritis
Digestive disease of the large intestine
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Diverticulitis
Medical condition
accessing iron in the blood, which causes anemia that is apparent at birth. It can lead to pallor, fatigue, and slow growth. The iron overload aspect of
Hypochromic_anemia
Inflammation of the pancreas
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Pancreatitis
Protrusion of abdominal contents through the inguinal canal in the pelvis
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Inguinal_hernia
Medical condition
Hemochromatosis is a rare, severe, and non-hereditary disease. It is a secondary iron overload with extrahepatic siderosis caused by severe fetal liver injury. This
Neonatal_hemochromatosis
Medical condition
Haemochromatosis type 3 is a type of iron overload disorder associated with deficiencies in transferrin receptor 2. It exhibits an autosomal recessive
Haemochromatosis_type_3
viscosity Reduced net transfused volume of red blood cells, which reduces iron overload. However, there are also potential risks associated with an exchange
Transfusion therapy (Sickle-cell disease)
Transfusion_therapy_(Sickle-cell_disease)
Effect of alcohol consumption on the human body
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Alcohol_flush_reaction
Inflammation of the colon (large intestine)
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Colitis
Inflammation of the small intestine
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Enteritis
Genetic disorder causing red blood cells to be spherical
patients who are heterozygous for a hemochromatosis gene may exhibit iron overload, despite the hemochromatosis genes being recessive. In chronic patients
Hereditary_spherocytosis
Medical condition where fat accumulates in the liver
quantitative MRI techniques such as proton density fat-fraction mapping and iron-corrected T1 (cT1) mapping techiques. Decreasing caloric intake by at least
Fatty_liver_disease
Type of joint disorder
following diseases: Psoriasis Reactive arthritis Ehlers–Danlos syndrome Iron overload Hepatitis Lyme disease Sjögren's disease Hashimoto's thyroiditis Celiac
Arthritis
Medical blood test to measure transferrin
very late in the disease. This is in contrast to transfusional iron overload in which iron deposition occurs first in the reticuloendothelial cells and
Total_iron-binding_capacity
Abnormal exit of tissues or organs from the cavity they usually reside in
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Hernia
Hole in the wall of the gastrointestinal tract
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Gastrointestinal_perforation
Intestinal inflammation causing bloody diarrhea
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Dysentery
Entrance of abdominal organs into the middle chest through the diaphragm
may include trouble swallowing and chest pains. Complications may include iron deficiency anemia, volvulus, or bowel obstruction. The most common risk factors
Hiatal_hernia
Medical condition
polymorphisms have currently been firmly linked to alcoholic liver disease. Iron overload (hemochromatosis). Diet: Malnutrition, particularly vitamin A and E
Alcoholic_liver_disease
Autoimmune disorder
nutritional deficiencies. Common deficiencies in coeliac disease include iron, folate, zinc, vitamin D, and vitamin B12. Vitamin D deficiency can cause
Coeliac_disease
Iron-based medication
event of known iron overload or iron utilization disorders. Iron polymaltose must not be administered at the same time as parenteral iron preparations.
Iron_polymaltose
Abnormal growth of tissue projecting from a mucous membrane
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Polyp_(medicine)
Allergic inflammatory condition of the esophagus
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Eosinophilic_esophagitis
Inflammation of the appendix
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Appendicitis
Dilated veins in the lower oesophagus
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Esophageal_varices
Abnormal dilation of the large intestine
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Megacolon
Narrowing of the lower esophagus due to mucosal or muscular tissue
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Schatzki_ring
Digestive system in humans
which is sent to the liver and secreted in the bile. Another product is iron, which is used in the formation of new blood cells in the bone marrow. Medicine
Human_digestive_system
Bowel movement consisting of fresh blood
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Hematochezia
Precancerous tissue formation in the esophagus
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Barrett's_esophagus
Reduced ability of blood to carry oxygen
anemia), blood loss, and fluid overload (hypervolemia). Globally, the most common underlying cause of anemia is dietary iron deficiency, followed by the
Anemia
Disease of the small intestine
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Jejunitis
Presence of excess fat in feces
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Steatorrhea
Medical condition
forms of iron overload can be thought of as relative hepcidin deficiency in one way or another[1]. For instance, a severe form of iron overload, juvenile
Iron_metabolism_disorder
Type of metal poisoning
immediately. A quick response to iron poisoning can significantly improve clinical outcomes. Overnutrition Iron overload Manoguerra, Anthony S.; Erdman
Iron_poisoning
Flow of stomach contents into the esophagus
are or may be allergic to titanium, stainless steel, nickel, or ferrous iron materials. A warning advises that the device should not be used by patients
Gastroesophageal reflux disease
Gastroesophageal_reflux_disease
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Proctocolitis
Chronic, autoimmune disease of the liver
alone are not enough for the diagnosis of autoimmune hepatitis Iron overload - elevated iron in the body can cause liver inflammation The choice for medical
Autoimmune_hepatitis
Marvel Studios film
Iron Man is a 2008 American superhero film based on the Marvel Comics character Iron Man. Produced by Marvel Studios and distributed by Paramount Pictures
Iron_Man_(2008_film)
Bodily stone made of feces
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Fecalith
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Pyloric_stenosis
Medical symptom or condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Nausea
Inability to digest lactose
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Lactose_intolerance
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Acute_pancreatitis
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Microscopic_colitis
Medical techniques to separate one or more components of blood
Erythrocytapheresis – removal of erythrocytes (red blood cells) in people with iron overload as a result of Hereditary haemochromatosis. This process is also used
Apheresis
Protrusion of abdominal contents through the abdominal wall
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Umbilical_hernia
Break or tear in anal canal skin
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Anal_fissure
Inflammatory bowel disease that causes ulcers in the colon
disease flares. Chronic bleeding from the GI tract, chronic inflammation, and iron deficiency often lead to anemia, which can affect quality of life. The clinical
Ulcerative_colitis
Folding of part of the intestine into itself
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Intussusception (medical disorder)
Intussusception_(medical_disorder)
Mammalian protein found in Homo sapiens
Medical professionals may check serum transferrin level in iron deficiency and in iron overload disorders such as hemochromatosis. Drosophila melanogaster
Transferrin
Abnormal presence of gases in the peritoneal cavity of the abdomen
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Pneumoperitoneum
Inflammation of the stomach and small intestine
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Gastroenteritis
Disease where stones form in the gallbladder
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Gallstone
Medical condition
and headache. Some patients may have bronze-colored skin due to an overload of iron. Patients with syndromic hereditary sideroblastic anemia may experience
Sideroblastic_anemia
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Zenker's_diverticulum
Inflammation of the stomach lining
(NSAIDs) such as aspirin, ibuprofen, and naproxen. Other drugs include cocaine, iron, colchicine when administered at toxic levels, kayexalate (a kind of polystyrene
Gastritis
Disruption to the propulsive ability of the intestine
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Ileus
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Proctalgia_fugax
Medical condition with dark feces
in the blood being altered by digestive enzymes and intestinal bacteria. Iron supplements may cause a grayish-black stool that should be distinguished
Melena
American journalist
at the National Institute of Health Clinical Center before dying of iron overload from the transfusions he had as treatment of his severe immune disorder
Elizabeth_DeVita-Raeburn
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Dumping_syndrome
Ulceration of the gastrointestinal tract
vomiting. melena (tarry, foul-smelling feces due to presence of oxidized iron from hemoglobin); rarely, an ulcer can lead to a gastric or duodenal perforation
Peptic_ulcer_disease
Human disease-causing mutation
degenerative changes there by oxidation cascades.[citation needed] Iron overload primarily affects nerve cells in the substantia nigra and basal ganglia
HFE_H63D_gene_mutation
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Enterocolitis
Type of fluid replacement used to prevent and treat dehydration
only with care, infusing slowly to avoid flooding the circulation and overloading the heart. Feeding should usually resume within 2–3 hours after starting
Oral_rehydration_therapy
Medical condition
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Duodenitis
Twisting of part of the intestine, causing a bowel obstruction
Hepatorenal syndrome Peliosis hepatis Metabolic disorders Wilson's disease Iron overload Gallbladder Cholecystitis Gallstone / Cholelithiasis Cholesterolosis
Volvulus
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IRON OVERLOAD
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IRON OVERLOAD
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