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2020 book by Abigail Shrier
Irreversible Damage: The Transgender Craze Seducing Our Daughters is a 2020 book by Abigail Shrier, published by Regnery Publishing, which endorses the
Irreversible_Damage
Destruction or degeneration of brain cells
Brain injury, also known as brain damage or neurotrauma, is the destruction or degeneration of brain cells. It may result from external trauma, such as
Brain_injury
American freelance journalist and author
opinion pieces for the Wall Street Journal. In 2020, Shrier's book Irreversible Damage: The Transgender Craze Seducing Our Daughters was published by Regnery
Abigail_Shrier
Webcomic
A Lesson Is Learned But The Damage Is Irreversible (ALILBTDII) is a webcomic drawn by David Hellman and written by Dale Beran. Ted Rall described the comic
A Lesson Is Learned but the Damage Is Irreversible
A_Lesson_Is_Learned_but_the_Damage_Is_Irreversible
2023 studio album by Algiers
released through Matador Records on February 24, 2023. The single "Irreversible Damage", featuring Zack de la Rocha, was released in October 2022. "Something
Shook_(album)
American medical doctor and skeptic (1945–2023)
Eckert, AJ (July 4, 2021). "Irreversible Damage to the Trans Community: A Critical Review of Abigail Shrier's Irreversible Damage (Part One)". sciencebasedmedicine
Harriet_Hall
Incan archaeological artifact in Peru
drugs was arrested after hitting the stone with a hammer, causing "irreversible damage" and breaking off multiple fragments. Inca architecture Inca civilization
Twelve-angled_stone
Process of decreasing or eliminating a remnant magnetic field
Degaussing, or deperming, is the process of decreasing or eliminating a remnant magnetic field. It is named after the gauss, a unit of magnetism, which
Degaussing
Risk management strategy
according to their capabilities. Where there are threats of serious or irreversible damage, lack of full scientific certainty shall not be used as a reason
Precautionary_principle
American post-punk band
years. They quickly followed it up with the blistering single, "Irreversible Damage", which featured a rare verse from Rage Against the Machine's Zack
Algiers_(band)
Damaging changes to a biological cell
biological, nutritional or immunological factors. Cell damage can be reversible or irreversible. Depending on the extent of injury, the cellular response
Cell_damage
Biblical figure; Phoenician princess and wife of Ahab
Asherah worship and was responsible for Naboth's death. This caused irreversible damage to the reputation of the Omride dynasty, who were already unpopular
Jezebel
Small bumps on the head of the human penis
physically dangerous techniques for papule removal which can result in irreversible damage. Since dermatologists have safe, effective ways to remove the papules
Pearly_penile_papules
American murderers and brothers
brothers filed motions for a mistrial, claiming that they suffered irreversible damage in the penalty phase as a result of possible misconduct and ineffective
Lyle_and_Erik_Menendez
Activity of trying to catch fish
techniques (such as electrocution, blasting and poisoning) that can do irreversible damage to local ecosystems by killing or sterilizing entire fish stocks
Fishing
Medical condition
pancreas, or as chronic damage with persistent pain or malabsorption. It is a disease process characterized by irreversible damage to the pancreas as distinct
Chronic_pancreatitis
central serous chorioretinopathy, is the fourth most common cause of irreversible damage to the macula:. The term "pachychoroid" was first introduced in 2013
Pachychoroid disorders of the macula
Pachychoroid_disorders_of_the_macula
Historical landform in southern Ukraine
the 1950s. The creation of the Kakhovka Reservoir in 1956 caused irreversible damage to what remained of the original landscape. The reservoir was destroyed
Great_Meadow,_Ukraine
Structure in the human male reproductive system
and blocks its own blood supply. Testicular torsion may result in irreversible damage to the testicle within hours. A collection of serous fluid in the
Spermatic_cord
Disproportionation of CO into CO2 and elemental carbon
an eyesore; sooting (also called coking) can cause serious, even irreversible, damage to catalysts and catalyst beds. This is a problem in the catalytic
Boudouard_reaction
Form of sexual play
one of the greatest risks in cock and ball torture and may cause irreversible damage. Bleeding is an indicator of unsafe behavior. Because numbness may
Cock_and_ball_torture
Series of fortifications in northern China
excavator to pass through. Police described the act as causing "irreversible damage to the integrity of the Ming Great Wall and to the safety of the
Great_Wall_of_China
Physical care and treatment of film-based materials
faces irreversible damage, including image loss. It's important to digitize or duplicate these materials before they face irreversible damage. Cold storage
Conservation and restoration of film
Conservation_and_restoration_of_film
Consequences of nuclear explosions
harm, causing mass casualties, long-lasting radiation effects, and irreversible damage to ecosystems. The subject has become important in international
Humanitarian impact of nuclear weapons
Humanitarian_impact_of_nuclear_weapons
Destructive fishing practices are fishing practices which easily result in irreversible damage to habitats and the sustainability of the fishery ecosystems. Such
Destructive_fishing_practices
Process for removing yellowing from ABS plastic
retrobrighting acts only as a temporary fix and that all methods may cause irreversible damage to the appearance of ABS plastic. The usage has also expanded to
Retrobright
2024 animated comedy film
threatening the cosmic balance. If Moopoo remains on Earth, he could cause irreversible damage. Freddy and Batty plan to find Max to use the portal spell to get
200%_Wolf
South Korean film
stay in the intensive care unit. Doctors said Na-young sustained irreversible damage to her genitals, anus and intestines, which initially required her
Hope_(2013_film)
American conservative book publisher
A.J. (July 4, 2021). "Irreversible Damage to the Trans Community: A Critical Review of Abigail Shrier's book Irreversible Damage (Part One)". Science-Based
Regnery_Publishing
American musician, lead singer of Rage Against the Machine (b. 1970)
from Run the Jewels 3 (2016) "Ju$t" from Run the Jewels 4 (2020). "Irreversible Damage" from Shook by Algiers (2023) McIver, Joel (2014). Know Your Enemy:
Zack_de_la_Rocha
Temporary blindness after a flash
brightness: dazzle, after image formation, flash blindness, and irreversible damage. [...] Flash blindness occurs when an extremely bright flash is discharged
Flash_blindness
Dye with two chemical forms
Temperatures above about 200–230 °C (392–446 °F) typically cause irreversible damage to leuco dyes; a time-limited exposure of some types to about 250 °C
Leuco_dye
Fad diet fixed on ideas about types of food drawn from Zen Buddhism
Their report concluded that "when a diet has been shown to cause irreversible damage to health and ultimately lead to death, it should be roundly condemned
Macrobiotic_diet
Website covering issues in science and medicine, focusing on quackery
Science-Based Medicine published a book review of Abigail Shrier's Irreversible Damage written by founding editor Harriet Hall. In her review, Hall wrote
Science-Based_Medicine
Methodology on technology control
precautionary principle as ""Where there are threats of serious or irreversible damage, lack of full scientific certainty shall not be used as a reason
Collingridge_dilemma
Private town in Malaysia
development has had significant negative environmental impact, with irreversible damage due to reclamation of ecologically sensitive coastal wetlands. The
Forest_City,_Johor
Disorders or diseases of the brain
cases, the encephalopathy may cause permanent structural changes and irreversible damage to the brain. These permanent deficits can be considered a form of
Encephalopathy
Gangs of street children in the Philippines
discomfort to the user after inhalation, but permanent damage from inhalants is irreversible. Damage to organs such as the liver, kidneys, brain, and heart
Rugby_boy
(24 January 2012). "Liverpool's world heritage waterfront faces 'irreversible damage', report says". The Guardian. Retrieved 21 July 2021. Buckley, Julia
Former_World_Heritage_Sites
Group of vitamins
symptoms of mania and psychosis. Untreated, it is possible to cause irreversible damage to the brain and nerve system; in rare extreme cases, paralysis can
B_vitamins
1995 building collapse in Seoul, South Korea
units were shut off, it was too late: the structure had suffered irreversible damage, and the fifth floor slab around column 5E finally gave way.[citation
Sampoong Department Store collapse
Sampoong_Department_Store_collapse
RF connector for coaxial cables
accept the larger 50 ohm pin without irreversible damage, while others do not. In general a 50 ohm socket is not damaged by a 75 ohm pin, but the loose fit
N_connector
Hollow part of the root of a tooth
and sensory nerves carry signals back to the brain. In the case of irreversible damage to the pulp, root canal treatment can relieve associated dental pain
Root_canal
Electromechanical malfunctioning
best this will cause irreversible damage and data loss where contact was made. In the worst case the debris scraped off the damaged area may contaminate
Hard_disk_drive_failure
Surfactant and antiseptic agent
004% to 0.01%. Stronger concentrations can be caustic and cause irreversible damage to the corneal endothelium. Avoiding the use of benzalkonium chloride
Benzalkonium_chloride
Standardised phrases specifying risks associated with substances
R39 Danger of very serious irreversible effects R40 Limited evidence of a carcinogenic effect R41 Risk of serious damage to eyes R42 May cause sensitisation
List_of_R-phrases
One-way valve present between right auricle and right ventricle
possibly annular dilation and is usually pathologic which can lead to irreversible damage of cardiac muscle and worse outcomes due to chronic prolonged right
Tricuspid_valve
Dissolution of the chromatin in a dying cell
necrosis, a form of cellular injury in which living tissue undergoes irreversible damage through premature cell death. Unlike apoptosis, which is a regulated
Karyolysis
Cave in Chiang Rai province, Thailand
drastic changes to the cave, as even minor disturbances can lead to irreversible damage and the potential extinction of these specialized species, highlighting
Tham_Luang_Nang_Non
British politician (born 1988)
had an accident in which he shattered his right hip, leading to irreversible damage to his knee and spine; for four years following the accident he was
Liam_Conlon
Preservation of heritage collections
as many adhesives, liquid cleaners, and protective coatings may irreversibly damage the object. Many museums contain objects in their collection that
Conservation and restoration of bone, horn, and antler objects
Conservation_and_restoration_of_bone,_horn,_and_antler_objects
Species of cactus
Spider mites cause damage by sucking out vital nutrients from the plant. Large populations of mites can cause irreversible damage, eventually killing
Cleistocactus_strausii
bacterial diarrhea, mycoplasmal infections, gonorrhea Nausea (rare), irreversible damage to central nervous system (uncommon), tendinosis (rare) Inhibits
List_of_antibiotics
Act of trying to kill oneself which the person survives
failure). Individuals who jump from a height and survive may face irreversible damage to multiple organs, as well as the spine and brain. While a majority
Suicide_attempt
Degree of resistance to, or protection from, harm
depletion is a classic Malthusian problem and is sadly resulting in some irreversible damage to stocks. The sperm whale was driven to near extinction by the demand
Security
Common name for several species of land turtle
a special permit. Collecting wild-hatched box turtles can cause irreversible damage to populations, because these turtles have a low reproductive rate
Box_turtle
Form of the drug cocaine
as a lost generation. They were predicted to suffer from severe, irreversible damage, including reduced intelligence and social skills. It was later found
Crack_cocaine
Legal decision or proceeding during which not all parties to the dispute are present
would allow him or her to cause irreversible damage before the notice takes effect. Stark and Choplin argued that such damage would be possible if ex parte
Ex_parte
President of Israel from 1978 to 1983
implications: "This action is immoral and ineffective and will cause irreversible damage in the long and short run to Palestinian children and to our own
Yitzhak_Navon
Largest juniper tree in the United States
years. He could see how the site was being degraded and foresaw irreversible damage was on the verge of happening. Although the mission of the League
Bennett_Juniper
Largest ocean on Earth
consequences for the ocean. It disrupts deep-sea ecosystems and may cause irreversible damage to fragile marine habitats. Sediment stirring and chemical pollution
Pacific_Ocean
Neurological disorder
changes associated with advanced stage/chronic MBD usually indicated irreversible damage and is associated with a poor prognosis/outcome. Chronic alcohol
Marchiafava–Bignami_disease
Capacity loss in rechargeable batteries
charging current by the remaining cells, potentially leading to irreversible damage. Whiskers can also form (i.e., "precipitate") after the temperature
Memory_effect
Power supply with electrochemical cells
lead to a battery explosion, in addition to leakage or irreversible damage. It may also cause damage to the charger or device in which the overcharged battery
Electric_battery
2023 horror novel by Alison Rumfitt
novel, describes her transition as "irreparable damage," a play on the title of Irreversible Damage by the American journalist Abigail Shrier. Megan
Brainwyrms
Material that breaks up into parts instead of deforming as one
transmission when cut; and other devices or materials that display irreversible damage or changes when manipulated. "Take a look at a new frangible trakehner
Frangibility
Protective gear for the eyes
enter from around or under protective eye equipment. Serious and irreversible damage can occur when chemical substances contact the eyes in the form of
Eye_protection
Highly reactive molecules formed from diatomic oxygen (O2)
and tolerance to various types of stress. However, ROS can cause irreversible damage to DNA as they oxidize and modify some cellular components and prevent
Reactive_oxygen_species
Fictional species in the Fallout franchise
to it. Ghouls are sterile and incapable of procreation due to the irreversible damage caused by radiation to their reproductive systems. "Born ghouls"
Ghoul_(Fallout)
Neurological disorders
surgically untether the spinal cord though there might already be irreversible damage. In tethered spinal cord cases spina bifida can be accompanied by
Tethered_cord_syndrome
"warn[ed] that the conduct of the United States and Israel has inflicted irreversible damage on humanity’s cultural heritage". Cultural genocide List of attacks
Destruction of cultural heritage during the 2026 Iran war
Destruction_of_cultural_heritage_during_the_2026_Iran_war
Controversy surrounding a hypothesized medical condition
while Abigail Shrier, who later published the controversial book Irreversible Damage about the concept, called it an explanation for the experiences of
Rapid-onset gender dysphoria controversy
Rapid-onset_gender_dysphoria_controversy
Group of medical conditions characterized by irregular heartbeat
poisoning of the AV node (with drugs that impair conduction) or by irreversible damage to the node. Bradycardias may also be present in the normally functioning
Arrhythmia
American right-to-die legal case
(/ˈʃaɪvoʊ/; née Schindler; December 3, 1963 – March 31, 2005), a woman in an irreversible permanent vegetative state. Schiavo's husband and legal guardian argued
Terri_Schiavo_case
Operation to remove mucosa of the maxillary sinus
Caldwell-Luc antrostomy, and Radical antrostomy, is an operation to remove irreversibly damaged mucosa of the maxillary sinus. It is done when maxillary sinusitis
Caldwell-Luc_surgery
Species of snake
β-caerulotoxins) being the primary neurotoxic components. These toxins irreversibly damage motor nerve terminals by depleting synaptic vesicles and disrupting
Common_krait
Professor Ludwig Von Drake have to stop Cheryl before she causes irreversible damage to Bonkers' brain. 45 4 "What You Read Is What You Get" October 7
List_of_Bonkers_episodes
Book series by Jessica Townsend
using their Witness powers to find and stop them before they cause irreversible damage. Meanwhile, Unit 919 is forced to continue classes, with Morrigan
The_Nevermoor_series
British politician (born 1982)
2 August 2024. Cates, Miriam (4 July 2024). "Labour could cause irreversible damage in government". The Critic Magazine. Retrieved 2 August 2024. Cates
Miriam_Cates
Heroin-based recreational drug
manifest. The acetaminophen content of the drug induces severe, irreversible damage to the liver when taken in high doses for long periods of time. Very
Cheese_(recreational_drug)
American lawyer and activist (born 1982)
journalist Glenn Greenwald criticized Strangio's comments about the book Irreversible Damage: The Transgender Craze Seducing Our Daughters by Abigail Shrier.
Chase_Strangio
Cerebrospinal fluid lesion in the spinal canal
the need to repeat the procedure. Removal of the cyst results in irreversible damage to the intersecting spinal nerve. Although fibrin-glue therapy initially
Tarlov_cyst
Model of human interaction proposed in 1968
games:[citation needed] socially acceptable, undesirable but not irreversibly damaging may result in drastic harm. The Karpman triangle was an adaptation
Karpman_drama_triangle
Song sung by Marilyn Monroe in 1962
posted a comparison image of the dress which showed significant irreversible damage which occurred after the gala event. In the 1987 season three, sixth
Happy_Birthday,_Mr._President
Abnormally low levels of albumin in the blood
generally considered to be a sign of advanced hepatic cirrhosis, or irreversible damage to the liver. Production of albumin can be 60–80% lower in advanced
Hypoalbuminemia
2025 studio album by the Weather Station
7. "Ribbon" 3:18 8. "Fleuve" 1:10 9. "Humanhood" 4:11 10. "Irreversible Damage" Erin Orsztynova 5:36 11. "Lonely" 4:36 12. "Aurora" Lindeman Adams
Humanhood
Class of vitamins
paresthesia, depression, cognitive decline, ataxia, and even irreversible nerve damage. In infants, untreated deficiency may result in neurological impairment
Vitamin_B12
1977 international festival in Lagos, Nigeria
throughout the building; this let in water, which eventually caused irreversible damage to the equipment and floors. Power was then cut from the building
FESTAC_77
2021 book by Kathleen Stock
women's prisons despite evidence to the contrary being available. Irreversible Damage, a 2020 book by Abigail Shrier Trans: When Ideology Meets Reality
Material Girls: Why Reality Matters for Feminism
Material_Girls:_Why_Reality_Matters_for_Feminism
Alleged and confirmed Russian-linked sabotage incidents across Europe since 2022
Most confirmed sabotage incidents avoided large-scale casualties or irreversible damage to strategic assets that could be seen as an overt act of war. Some
Russian sabotage operations in Europe
Russian_sabotage_operations_in_Europe
International standard managed by the United Nations
dermal) or LC50 (inhalation). Skin corrosion means the production of irreversible damage to the skin following the application of a test substance for up
Globally Harmonized System of Classification and Labelling of Chemicals
Globally_Harmonized_System_of_Classification_and_Labelling_of_Chemicals
Church in Brussels, Belgium
historic buildings, advised against any carving, at the risk of causing irreversible damage to the ageing stones. All that was done was to treat the exterior
Church_of_Our_Lady_of_Laeken
2013–2016 Chinese land reclamation in the disputed South China Sea
8 billion cu ft) of sand and corals, resulting in significant and irreversible damage to the environment. Frank Muller-Karger, professor of biological
Great_Wall_of_Sand
Inflammation of inner tissue (pulp) of a tooth
This is the condition where the pulp is irreversibly damaged. The pulp cannot recover from the insult and damage. For example, decay that has reached the
Pulpitis
Ancient Mesoamerican city
perforations for the project have caused fractures in stones and irreversible damage, while the project will have limited benefit. In May 2021, the Secretariat
Teotihuacan
Town in Tafilah Governorate, Jordan
rich ancient history. Archaeologists believe that the site suffered irreversible damage after Nebuchadnezzar II invaded it. It was later occupied by the
Busaira,_Jordan
2026 diplomatic and energy crisis
pipeline remained technically functional despite Ukrainian reports of irreversible damage from Russian drone strikes. According to Fico, both parties reached
2026_Druzhba_pipeline_dispute
Mexican singer (1948–2019)
addition to neurological damage, the aftereffects of pneumonia, and the impact of alcoholism and smoking, outcoming in irreversible damage to his vocal apparatus
José_José
Damage to the retina of the eyes
disease course. Patients often become symptomatic when there is irreversible damage. Symptoms are usually not painful and can include:[citation needed]
Retinopathy
American musician, filmmaker and curator
Director 2016 Burn to Shine 6: Atlanta Burn to Shine Curator 2023 "Irreversible Damage" Algiers Director 2023 "I Can't Stand It!" Algiers Director 2025
Lee_Tesche
travel, tourism, insurance
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