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LEPODISIRAN

  • Lepodisiran

    • Small interfering RNA

    Lepodisiran (LY3819469) is a small interfering RNA that was developed to reduce lipoprotein(a) in people at risk of cardiovascular disease. It was developed

    Lepodisiran

    Lepodisiran

  • Lipoprotein(a)

    • Low-density lipoprotein containing apolipoprotein(a)

    Lp(a), including pelacarsen (80% reduction), olpasiran (95% reduction), lepodisiran (94% reduction), and muvalapin (47-86% reduction). A meta-analysis of

    Lipoprotein(a)

    Lipoprotein(a)

    Lipoprotein(a)

  • Pelacarsen

    • Experimental antisense oligonucleotide drug for lowering lipoprotein(a)

    development include small interfering RNAs (siRNAs) such as olpasiran, lepodisiran, and zerlasiran, which also target LPA messenger RNA. Additionally, oral

    Pelacarsen

    Pelacarsen

  • 2023 in science

    • 2-trialed Mazdutide against type-2 diabetes (9 Nov), phase 1-trialed lepodisiran against cardiovascular risk factor lipoprotein (12 Nov), rat-tested depot

    2023 in science

    2023_in_science

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