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Cell biology concept
Macropinosomes are a type of cellular compartment that form as a result of macropinocytosis. Macropinosomes have been described to form via a wave-like
Macropinosome
Mode of endocytosis to bring small particles into a cell
onto the membrane, large fluid-filled endocytic vesicles form called macropinosomes, which can transiently increase the bulk fluid uptake of a cell by up
Pinocytosis
Protein found in humans
component filamentous actin cell projection membrane plasma membrane macropinosome cell leading edge extracellular exosome cytoskeleton nucleus lamellipodium
CARMIL1
Family of related toxins
similar to that of the plant toxin ricin. After entering a cell via a macropinosome, the payload (A subunit) cleaves a specific adenine nucleobase from
Shiga_toxin
Genus of virus
macropinocytosis leads to the formation of macropinocytosis-specific endosomes (macropinosomes), which are large enough to accommodate Ebola virions. This discovery
Ebolavirus
Vacuole to which materials ingested by endocytosis are delivered
specialized cells such as polarized cells and macrophages. Phagosomes, macropinosomes and autophagosomes mature in a manner similar to endosomes, and may
Endosome
Italian chemist
breaking in intestinal organoid development The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS Liberali is married with
Prisca_Liberali
Protein-coding gene in the species Homo sapiens
vesicle vesicle early phagosome ruffle membrane early phagosome membrane macropinosome phagocytic vesicle membrane cell projection phagocytic vesicle Biological
APPL2
Protein-coding gene in humans
binding protein binding metal ion binding Cellular component cytoplasm macropinosome retromer complex lysosomal membrane early endosome endosome membrane
ANKFY1
Protein-coding gene in the species Homo sapiens
endosome ruffle plasma membrane cytoplasmic vesicle early phagosome macropinosome intracellular vesicle cell projection phagocytic vesicle Biological
APPL1
Species of virus
confirmed). After infection, the virus enters into lymphocytes via macropinosomes.[citation needed] Once the virus newly infects a cell, the lipid membrane
Kaposi's sarcoma-associated herpesvirus
Kaposi's_sarcoma-associated_herpesvirus
Species of virus affecting humans and animals
through the glycoprotein (GP) surface peplomer and is endocytosed into macropinosomes in the host cell. To penetrate the cell, the viral membrane fuses with
Zaire_ebolavirus
Protein-coding gene in the species Homo sapiens
component of membrane extracellular matrix cytoplasmic vesicle melanosome macropinosome intermediate filament cytoskeleton Biological process ossification angiogenesis
MMP14
Protein-coding gene in the species Homo sapiens
GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation". J Biol Chem. 278 (6): 4063–71. doi:10.1074/jbc
RAB34
Protein-coding gene in humans
a marker for dendritic cells and is involved in the trafficking of macropinosomes to the cytoskeleton, supporting a function-based concept of Hodgkin
CLIP1
Protein found in humans
sheath adaxonal region Schmidt-Lanterman incisure PCSK9-AnxA2 complex macropinosome basement membrane cell surface lysosomal membrane basolateral plasma
Annexin_A2
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