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MRTFA

  • MRTFA

    • Protein-coding gene in humans

    Myocardin-related transcription factor A is a protein that in humans is encoded by the MRTFA gene (previously MKL1). The protein encoded by this gene is regulated by

    MRTFA

    MRTFA

    MRTFA

  • Down syndrome

    • Genetic disorder

    leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MRTFA) Other Ewing sarcoma t(11 FLI1; 22 EWS) Synovial sarcoma t(x SYT;18 SSX)

    Down syndrome

    Down syndrome

    Down_syndrome

  • Turner syndrome

    • X chromosome monosomy

    leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MRTFA) Other Ewing sarcoma t(11 FLI1; 22 EWS) Synovial sarcoma t(x SYT;18 SSX)

    Turner syndrome

    Turner syndrome

    Turner_syndrome

  • Birth defect

    • Condition present at birth regardless of cause

    leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MRTFA) Other Ewing sarcoma t(11 FLI1; 22 EWS) Synovial sarcoma t(x SYT;18 SSX)

    Birth defect

    Birth defect

    Birth_defect

  • Miscarriage

    • Natural premature termination of pregnancy

    leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MRTFA) Other Ewing sarcoma t(11 FLI1; 22 EWS) Synovial sarcoma t(x SYT;18 SSX)

    Miscarriage

    Miscarriage

    Miscarriage

  • MRTFB

    • Protein-coding gene in humans

    relevance for myogenic differentiation, motile function and addiction. MRTFA GRCh38: Ensembl release 89: ENSG00000186260 – Ensembl, May 2017 GRCm38:

    MRTFB

    MRTFB

    MRTFB

  • Fryns–Aftimos syndrome

    • Medical condition

    leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MRTFA) Other Ewing sarcoma t(11 FLI1; 22 EWS) Synovial sarcoma t(x SYT;18 SSX)

    Fryns–Aftimos syndrome

    Fryns–Aftimos syndrome

    Fryns–Aftimos_syndrome

  • Miscarriage and mental disorders

    • Medical condition

    leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MRTFA) Other Ewing sarcoma t(11 FLI1; 22 EWS) Synovial sarcoma t(x SYT;18 SSX)

    Miscarriage and mental disorders

    Miscarriage_and_mental_disorders

  • Miscarriage risks

    • Factors that increase the chance of a miscarriage

    leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MRTFA) Other Ewing sarcoma t(11 FLI1; 22 EWS) Synovial sarcoma t(x SYT;18 SSX)

    Miscarriage risks

    Miscarriage_risks

  • Polysomy

    • Abnormal multiples of one or more chromosomes

    leukemia t(15 PML,17 RARA) Acute megakaryoblastic leukemia t(1 RBM15;22 MRTFA) Other Ewing sarcoma t(11 FLI1; 22 EWS) Synovial sarcoma t(x SYT;18 SSX)

    Polysomy

    Polysomy

    Polysomy

  • List of human protein-coding genes 5

    • HGNC:16635; P82673 9872 MRRF HGNC:7234; Q96E11 9873 MRS2 HGNC:13785; Q9HD23 9874 MRTFA HGNC:14334; Q969V6 9875 MRTFB HGNC:29819; Q9ULH7 9876 MRTO4 HGNC:18477;

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

  • Acute megakaryoblastic leukemia

    • Blood marrow cancer originating in megakaryoblast cells

    involves the RBM15 gene on chromosome 1 and the MKL1 gene (also termed MRTFA) on chromosome 22 to create a RBM15-MKL1 fusion gene. Studies in mice indicate

    Acute megakaryoblastic leukemia

    Acute megakaryoblastic leukemia

    Acute_megakaryoblastic_leukemia

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