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Protein-coding gene in the species Homo sapiens
protein that in humans is encoded by the MTDH gene. MTDH (AEG-1) is involved in HIF-1alpha mediated angiogenesis. MTDH also interacts with SND1 and involved
MTDH
Multiprotein complex
facilitate the RLC. Recently identified members of RISC are SND1 and MTDH. SND1 and MTDH are oncogenes and regulate various gene expression. Ago, Argonaute;
RNA-induced_silencing_complex
Family of regulator genes
signaling in regulation of microRNAs (miR-29, miR-150, miR-17-92). c-Myc induces MTDH (AEG-1) gene expression and in turn itself requires AEG-1 oncogene for its
Myc
Protein
cell cultures and animal models. Nucleolin has been shown to interact with: MTDH, CSNK2A2, Centaurin, alpha 1, HuR, NPM1, P53, PPP1CB, S100A11, Sjögren syndrome
Nucleolin
HGNC:16111; O94964 9965 MTCL3 HGNC:21494; Q5TF21 9966 MTCP1 HGNC:7423; P56278 9967 MTDH HGNC:29608; Q86UE4 9968 MTERF1 HGNC:21463; Q99551 9969 MTERF2 HGNC:30779;
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
Precursor microRNA family
(MTDH) and EZH2. It further induces apoptosis, inhibition of colony formation and tumorigenesis of breast cancer cells in vivo. A decrease in MTDH and
Mir-26 microRNA precursor family
Mir-26_microRNA_precursor_family
Protein-coding gene in humans
interacts with splicing complex proteins KHDRBS3 (T-STAR) and Metadherin (MTDH) which also alter CD44 splicing. Subsequently, the knockdown of Sam68 has
KHDRBS1
Protein-coding gene in humans
been shown to interact with the protein metadherin, encoded by the oncogene MTDH acting to influence alternative splicing of tumour-related genes such as
YTHDC1
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