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Bacterium that causes tuberculosis
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative
Mycobacterium_tuberculosis
Closely related bacterium species that cause tuberculosis
includes: Mycobacterium tuberculosis Mycobacterium africanum Mycobacterium orygis Mycobacterium bovis and the Bacillus Calmette–Guérin strain Mycobacterium microti
Mycobacterium tuberculosis complex
Mycobacterium_tuberculosis_complex
Genus of bacteria
of the Mycobacterium tuberculosis complex demonstrates that Mycobacterium africanum, Mycobacterium bovis, Mycobacterium caprae, Mycobacterium microti
Mycobacterium
Species of bacterium
Mycobacterium bovis is a slow-growing (16- to 20-hour generation time) aerobic bacterium and the causative agent of tuberculosis in cattle (known as bovine
Mycobacterium_bovis
Bacterium that causes leprosy
obligate intracellular parasite, which means, unlike its relative Mycobacterium tuberculosis, it cannot be grown in cell-free laboratory media. This is likely
Mycobacterium_leprae
Species of bacterium
Mycobacterium vaccae vaccine include immunotherapy for allergic asthma, cancer, depression, leprosy, psoriasis, dermatitis, eczema and tuberculosis.
Mycobacterium_vaccae
Medical condition
extensively drug-resistant TB (XDR-TB). Tuberculosis is caused by infection with the bacterium Mycobacterium tuberculosis. Almost one in four people in the
Multidrug-resistant tuberculosis
Multidrug-resistant_tuberculosis
Methods for diagnosing tuberculosis
Tuberculosis is diagnosed by finding Mycobacterium tuberculosis bacteria in a clinical specimen taken from the patient. While other investigations may
Diagnosis_of_tuberculosis
Infectious disease
consumption, is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis initially infects the lungs, but it can also spread
Tuberculosis
Species of bacterium
of pulmonary tuberculosis. The symptoms of infection resemble those of M. tuberculosis. It is a member of the Mycobacterium tuberculosis complex. There
Mycobacterium_africanum
Disease treatment
drug-resistant tuberculosis (pre-XDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) in 2021. Pre-XDR-TB is now defined as TB due to Mycobacterium tuberculosis
Management_of_tuberculosis
State of tuberculosis infection without symptoms
when a person is infected with the bacterium Mycobacterium tuberculosis but does not have active tuberculosis (TB). The active form of the disease can be
Latent_tuberculosis
Growth medium used to culture Mycobacterium species
specially used for culture of Mycobacterium species, notably Mycobacterium tuberculosis. When grown on LJ medium, M. tuberculosis appears as brown, granular
Löwenstein–Jensen_medium
Long fatty acids found in the cell walls of the Mycobacteriales taxon
taxon, a group of bacteria that includes Mycobacterium tuberculosis, the causative agent of the disease tuberculosis. They form the major component of the
Mycolic_acid
Species of bacterium
Mycobacterium smegmatis is an acid-fast bacterial species in the phylum Actinomycetota and the genus Mycobacterium. It is 3.0 to 5.0 μm long with a bacillus
Mycobacterium_smegmatis
Species of bacterium
Mycobacterium caprae is a species of bacteria in the genus Mycobacterium and a member of the Mycobacterium tuberculosis complex. The species is named
Mycobacterium_caprae
2025 nonfiction book by John Green
tuberculosis, a curable disease usually brought on by the bacteria Mycobacterium tuberculosis that is the leading cause of death from an infectious disease
Everything_Is_Tuberculosis
Mycobacterium tuberculosis contains at least nine small RNA families in its genome. The small RNA (sRNA) families were identified through RNomics – the
Mycobacterium tuberculosis sRNA
Mycobacterium_tuberculosis_sRNA
Species of bacterium
Mycobacterium microti is a member of the Mycobacterium tuberculosis complex (MTBC) known as the 'Vole bacillus', first described as a pathogen of field
Mycobacterium_microti
that Mycobacterium tuberculosis must cause a pulmonary disease in order to be successfully transmitted from one person to another. Tuberculosis, better
List of antibiotic-resistant bacteria
List_of_antibiotic-resistant_bacteria
Chemical compound
in the cell wall of Mycobacterium tuberculosis and similar species. It is the primary lipid found on the exterior of M. tuberculosis cells. Cord factor
Cord_factor
Species of bacterium
Mycobacterium canettii, a novel pathogenic taxon of the Mycobacterium tuberculosis complex (MTBC), was first reported in 1969 by the French microbiologist
Mycobacterium_canettii
disease. Tuberculosis is an infectious disease caused by bacteria of the Mycobacterium tuberculosis complex (MTBC). Throughout history, tuberculosis has been
History_of_tuberculosis
Tuberculosis disgnostic and antibiotic sensitivity test
rapid tuberculosis diagnosis and rapid antibiotic sensitivity test. It is an automated diagnostic test that can identify Mycobacterium tuberculosis (MTB)
GeneXpert_MTB/RIF
Species of bacterium
Mycobacterium marinum is a slow growing fresh and saltwater mycobacterium (SGM) belonging to the genus Mycobacterium and the phylum Actinobacteria. It
Mycobacterium_marinum
Group of bacteria
Mycobacterium avium complex is a group of mycobacteria comprising Mycobacterium intracellulare and Mycobacterium avium that are commonly grouped because
Mycobacterium_avium_complex
Tuberculosis of the renal and genital organs
renal and genital tuberculosis lesions may be a component of disseminated miliary tuberculosis. Identification of Mycobacterium tuberculosis in urine through
Urogenital_tuberculosis
Species of bacterium
Mycobacterium pinnipedii is a member of the Mycobacterium tuberculosis complex which primarily infects seals. It is a slowly growing pathogenic Mycobacterium
Mycobacterium_pinnipedii
Species of bacterium
Mycobacterium kansasii is a bacterium in the Mycobacterium genus. It is an environmental bacteria that causes opportunistic infections in humans, and is
Mycobacterium_kansasii
Species of bacterium
related to Mycobacterium marinum, from which it evolved around one million years ago, and more distantly to the mycobacteria which cause tuberculosis and leprosy
Mycobacterium_ulcerans
Protein made by Mycobacterium tuberculosis
encoded by the esxB gene. CFP-10 is a 10 kDa secreted antigen from Mycobacterium tuberculosis. It forms a 1:1 heterodimeric complex with ESAT-6. Both genes
CFP-10
Species of bacterium
(2008). "The use of the name Mycobacterium w for the leprosy immunotherapeutic bacillus creates confusion with M. tuberculosis-W (Beijing strain): A suggestion"
Mycobacterium_indicus_pranii
Species of bacterium
Mycobacterium fortuitum is a nontuberculous species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of
Mycobacterium_fortuitum
Infection specificity of pathogens
complications such as microcephaly may occur. Mycobacterium tuberculosis is a human-tropic bacterium that causes tuberculosis - the second most common cause of death
Host_tropism
Tuberculosis that is resistant to the most effective drugs
testing of Mycobacterium tuberculosis against second-line drugs using the Bactec MGIT 960 System". The International Journal of Tuberculosis and Lung Disease
Extensively drug-resistant tuberculosis
Extensively_drug-resistant_tuberculosis
Chemical compound
its necessity in Mycobacterium tuberculosis. Accumulation of propionyl-CoA can lead to toxic effects. In Mycobacterium tuberculosis, it has been suggested
Propionyl-CoA
Biological process
tumour-suppressor genes. In 1999, the virulence genes associated with Mycobacterium tuberculosis were identified through transposon mutagenesis-mediated gene knockout
Transposon_mutagenesis
the kinase-mediated signaling networks in Mycobacterium tuberculosis, the causative pathogen of tuberculosis. Holder of a master's degree in biotechnology
Vinay_K._Nandicoori
Tuberculosis which spreads beyond the lungs
9% of males). Diagnosis requires culture or PCR detection of Mycobacterium tuberculosis in urine, supplemented by imaging studies showing characteristic
Extrapulmonary_tuberculosis
Bacteriological technique
diagnosing tuberculosis (caused by Mycobacterium tuberculosis) and other diseases caused by atypical mycobacteria, such as leprosy (caused by Mycobacterium leprae)
Ziehl–Neelsen_stain
Enzyme that metabolizes compounds containing epoxides
at least as it is detected in mouse liver. Mycobacterium tuberculosis, the causative agent of tuberculosis, expresses at least six different forms of
Epoxide_hydrolase
Medication
other drugs such as isoniazid and rifampicin in the treatment of Mycobacterium tuberculosis and as directly observed therapy (DOT). It is never used on its
Pyrazinamide
Professor of Microbiology
known for his research on Mycobacterium tuberculosis. His research on the discovery and characterization of the Mycobacterium smegmatis porin A (MspA)
Michael_Niederweis
Immunological test for tuberculosis
protein from Mycobacterium tuberculosis, obtaining purified protein derivative (PPD) and enabling the creation of a reliable test for tuberculosis. Her first
Mantoux_test
Virus infecting mycobacteria
isolated from the bacterial species Mycobacterium smegmatis and Mycobacterium tuberculosis, the causative agent of tuberculosis, more than 4,200 mycobacteriophage
Mycobacteriophage
Medical condition
meningitis, is a specific type of bacterial meningitis caused by the Mycobacterium tuberculosis infection of the meninges—the system of membranes which envelop
Tuberculous_meningitis
Protein made by Mycobacterium tuberculosis
kDa, is produced by Mycobacterium tuberculosis, it is a secretory protein and potent T cell antigen. It is used in tuberculosis diagnosis by the whole
ESAT-6
Antibiotic for treatment of tuberculosis
infection of Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). In persons with isoniazid-resistant Mycobacterium tuberculosis infection
Isoniazid
some studies use different animal species. Their function in Mycobacterium tuberculosis infection has been the main focus in past research. Group 1 CD1-restricted
Group 1 CD1-restricted T cells
Group_1_CD1-restricted_T_cells
Bacteria that can enter and survive in host cells
in the cytoplasm and nuclei of the host cell's they inhabit. Mycobacterium tuberculosis is an example of an intracellular bacterial species. There are
Intracellular_bacteria
Medical condition
such as those with uncontrolled HIV. Mycobacterium tuberculosis is the most common cause of both pulmonary tuberculosis and tuberculous lymphadenitis. Historically
Tuberculous_lymphadenitis
Medical condition
homelessness and HIV/AIDS. Miliary tuberculosis is a form of tuberculosis that is the result of Mycobacterium tuberculosis travelling to extrapulmonary organs
Miliary_tuberculosis
Infection that develops from a pre-existing condition
infection called mycobacterium avium-intracellulare infection. Mycobacterium tuberculosis is a species of bacteria that causes tuberculosis, a respiratory
Opportunistic_infection
Species of bacterium
AccuProbes to identify Mycobacterium avium complex, Mycobacterium tuberculosis complex, Mycobacterium kansasii, and Mycobacterium gordonae directly from
Mycobacterium_gordonae
Species of bacterium
Mycobacteroides abscessus (formerly Mycobacterium abscessus) is a species of rapidly growing, multidrug-resistant, nontuberculous mycobacteria (NTM) that
Mycobacteroides_abscessus
Medical condition
by demonstrating Mycobacterium tuberculosis in peritoneal fluid or in a biopsy specimen. The histopathologic findings of tuberculosis in biopsy, such as
Abdominal_tuberculosis
Glycolipid found in mycobacterial cell walls
and a virulence factor associated with Mycobacterium tuberculosis, the bacteria responsible for tuberculosis. Its primary function is to inactivate macrophages
Lipoarabinomannan
Class of enzymes
kinetics of Mycobacterium tuberculosis malate synthase have been well categorized. Malate synthase is essential to Mycobacterium tuberculosis survival because
Malate_synthase
Field of study
organisms like Mycobacterium tuberculosis. It is possible that the human genome has evolved in part from our exposure to M. tuberculosis. Animal model
Public_health_genomics
Species of bacterium
Mycobacterium lepromatosis is an aerobic, acid-fast bacillus (AFB), and the second known causative agent of Hansen's disease (leprosy). It was discovered
Mycobacterium_lepromatosis
Indian microbiologist
on pathogenesis, including drug resistance mechanisms in both mycobacterium tuberculosis (TB) and human immunodeficiency viruses (HIV). Amit Singh was
Amit_Singh_(scientist)
American biochemist
who co-discovered Streptomycin, the first antibiotic against Mycobacterium tuberculosis in Selman Waksman laboratory at Rutgers University. Waksman went
Elizabeth_Bugie
Study of the structure of every protein in a genome
targets in Mycobacterium tuberculosis, the bacterium that causes tuberculosis. The development of novel drug therapies against tuberculosis are particularly
Structural_genomics
Skin rash of small, red nodules due to infection by M. tuberculosis
the skin that may appear two to four weeks after inoculation by Mycobacterium tuberculosis in a previously infected and immunocompetent individual.[citation
Tuberculosis_verrucosa_cutis
Coenzyme
isoniazid, which is used in the treatment of tuberculosis, an infection caused by Mycobacterium tuberculosis. Isoniazid is a prodrug and once it has entered
Nicotinamide adenine dinucleotide
Nicotinamide_adenine_dinucleotide
Tuberculosis vaccine candidate
vaccine against tuberculosis in humans currently in clinical trials. It is based on a genetically modified form of the Mycobacterium tuberculosis pathogen isolated
MTBVAC
Subspecies of bacteria
drugs (which can generally kill Mycobacterium tuberculosis). MAP is susceptible to antibiotics used to treat Mycobacterium avium disease, such as rifabutin
Mycobacterium avium subsp. paratuberculosis
Mycobacterium_avium_subsp._paratuberculosis
functions as both catalase and peroxidase, a catalase-peroxidase. In Mycobacterium tuberculosis, mutations in KatG are commonly associated with resistance to
KatG
Vaccine primarily used against tuberculosis
he reported to Koch. By 1901 Koch distinguished Mycobacterium bovis from Mycobacterium tuberculosis. Following the success of vaccination in preventing
BCG_vaccine
Species of bacterium
Mycobacterium orygis is a species of the tuberculosis complex of the genus Mycobacterium. It causes tuberculosis in oryx, rhinos, dairy cattle, rhesus
Mycobacterium_orygis
Type of medical test
infection) is a condition where people have an immune response to Mycobacterium tuberculosis, the bacterium that causes TB, without any signs or symptoms of
Interferon gamma release assay
Interferon_gamma_release_assay
Abscess lacking signs of inflammation
associated with infections due to bacteria like Mycobacterium tuberculosis, the cause of tuberculosis, and fungi like those from the genus Blastomyces
Cold_abscess
Tuberculosis of the spine
issues, or a hoarse voice. Infection of the lungs by the bacteria Mycobacterium tuberculosis (MTB) eventually spreads through the host's body. Without treatment
Pott's_disease
Inflammation of the alveoli of the lungs
associated with Streptococcus pneumoniae, anaerobic organisms, and Mycobacterium tuberculosis; smoking facilitates the effects of Streptococcus pneumoniae,
Pneumonia
Painful facial skin nodules due to infection by M. tuberculosis
eyelids, lips, cheeks, ears and neck. It is the most common Mycobacterium tuberculosis skin infection. The lesions may ultimately develop into disfiguring
Lupus_vulgaris
Peruvian biologist
responsible for tuberculosis, with a particular emphasis on the mechanisms of resistance to pyrazinamide in Mycobacterium tuberculosis. Sheen Cortavarría
Patricia_Sheen
Some bacteria that do not cause tuberculosis
groups for diagnosis and treatment: Mycobacterium tuberculosis complex, which can cause tuberculosis: M. tuberculosis, M. bovis, M. africanum, M. microti
Nontuberculous_mycobacteria
Chemical compound
Pyrazinoic acid (POA) is a pyrazinamide (PZA) metabolite. Mycobacterium tuberculosis pyrazinamidase converts pyrazinamide into this compound, the active
Pyrazinoic_acid
Canadian microbiologist and researcher (born 1961)
in Mycobacterium tuberculosis, and COVID-19. His pioneering discovery of the "eukaryotic like" protein kinases and phosphatases in Mycobacterium tuberculosis
Yossef_Av-Gay
Abnormal change in size of the neck lymph nodes
(neck) lymph nodes associated with tuberculosis as well as nontuberculous (atypical) mycobacteria such as Mycobacterium marinum. Scrofula is the term used
Mycobacterial cervical lymphadenitis
Mycobacterial_cervical_lymphadenitis
Inflammation of membranes around the brain
infectious agents that cause chronic infectious meningitis such as mycobacterium tuberculosis, many fungal species and viruses are difficult to isolate from
Chronic_meningitis
Vaccines to prevent tuberculosis
repeated BCG, or combined BCG and killed Mycobacterium leprae vaccine for prevention of leprosy and tuberculosis in Malawi. Karonga Prevention Trial Group"
Tuberculosis_vaccines
Sterol biosynthesized by all animal cells
steroid generally associated with mammals, the human pathogen Mycobacterium tuberculosis is able to completely degrade this molecule and contains a large
Cholesterol
Medical condition
calves." Some sources define "paratuberculosis" by the lack of Mycobacterium tuberculosis, rather than the presence of any specific infectious agent, leaving
Paratuberculosis
Antibiotic medication
to treat several types of bacterial infections, including tuberculosis (TB), Mycobacterium avium complex, leprosy, and Legionnaires' disease. It is almost
Rifampicin
Protein family
3OQ8, PDB: 3EOL and PDB: 3E5B) and eleven structures from Mycobacterium tuberculosis (PDB: 1F61, PDB: 1F8I, PDB: 1F8M, PDB: 6C4A, PDB: 6C4C, PDB:
Isocitrate_lyase
activator or Bpa) is an ATP-independent proteasome activator of Mycobacterium tuberculosis that forms 12-fold symmetric rings and interacts with the 20S
Proteasome_accessory_factor_E
Process of preserving foods with heat
oral ingestion of infected milk) as well as of Mycobacterium tuberculosis (which causes tuberculosis) were later demonstrated. For all practical purposes
Pasteurization
Medical condition
inflammation of the ileum, a portion of the small intestine. Mycobacterium tuberculosis infection may mimic Crohn's disease Ileitis. Ileitis may be linked
Ileitis
Growth medium used to culture Mycobacterium species
liquid growth medium specially used for culture of Mycobacterium species, notably Mycobacterium tuberculosis. Ammonium sulfate L-Glutamic acid Sodium citrate
Middlebrook_7H9_Broth
Species of bacterium
Mycobacterium subsp. avium is a subspecies of the phylum Actinomycetota, belonging to the genus Mycobacterium. The subspecies name Mycobacterium avium
Mycobacterium avium subsp. avium
Mycobacterium_avium_subsp._avium
Biological database
focuses on tuberculosis antibiotic resistance genes. It is a highly structured, text-based database focusing on Mycobacterium tuberculosis at seven different
MUBII-TB-DB
Lung infection
Moraxella catarrhalis. Mycobacterium tuberculosis, the tubercle bacillus, may also cause lobar pneumonia if pulmonary tuberculosis is not treated promptly
Lobar_pneumonia
Chemical compound
is an isolate of Lessonia nigrescens that has activity against Mycobacterium tuberculosis. Wächter, G. A.; Franzblau, S. G.; Montenegro, G; Hoffmann, J
Saringosterol
chorismate → salicylic acid MbtI is the responsible enzyme from Mycobacterium tuberculosis. Zwahlen, Jacque; Kolappan, Subramaniapillai; Zhou, Rong; Kisker
Salicylate_synthase
Inflammatory aggregation of immune cells
granulomas and are not specific for tuberculosis. Mycobacterium tuberculosis can cause the granulomas of tuberculosis which tend to contain necrosis ("caseating
Granuloma
Infectious disease and significant cause of mortality in India
on December 30, 2019. The bacterium that causes TB is called mycobacterium tuberculosis. A person can unknowingly acquire this bacteria and have it lie
Tuberculosis_in_India
Bacterial strain
Mycobacterium tuberculosis strain H37Rv is the most studied strain of tuberculosis in research laboratories. It was first isolated by Dr. Edward R. Baldwin
H37Rv
Type of white blood cell
peroxides digest the pathogen. However, some bacteria (such as Mycobacterium tuberculosis) have become resistant to these methods of digestion. Typhoidal
Macrophage
studied as a virulence factor associated with the ESX-1 system in Mycobacterium tuberculosis. These secretion systems are often found in gram-positive bacteria
Type_VII_secretion_system
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