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Neointimal hyperplasia refers to proliferation and migration of vascular smooth muscle cells primarily in the tunica intima, resulting in the thickening
Neointimal_hyperplasia
Swirling and reverse current in a turbulent flow regime
concerning effects, including atherosclerotic lesions, postsurgical neointimal hyperplasia, in-stent restenosis, vein bypass graft failure, transplant vasculopathy
Eddy_(fluid_dynamics)
Medical implant to treat narrowed arteries
anti-proliferative medications—such as sirolimus or paclitaxel—that inhibit neointimal hyperplasia, the excessive tissue growth inside the artery that can lead to
Drug-eluting_stent
Recurrence of stenosis, a narrowing of a blood vessel
media, a smooth muscle wall in the vessel. This is also known as Neointimal Hyperplasia (NIHA). Vessel restenosis is typically detected by angiography,
Restenosis
Procedure to widen narrow arteries or veins
metal stents were found to cause in-stent restenosis as a result of neointimal hyperplasia and stent thrombosis, which led to the invention of drug-eluting
Angioplasty
Medication used for cancer
Ware M, et al. (May 2001). "Paclitaxel stent coating inhibits neointimal hyperplasia at 4 weeks in a porcine model of coronary restenosis". Circulation
Paclitaxel
Protein-coding gene in the species Homo sapiens
and in humans. Suppression of CCN1 expression results in reduced neointimal hyperplasia after balloon angioplasty, an effect that is reversed by delivery
CCN_family_member_1
Medical stent implanted into coronary arteries
(cell proliferation) to rapidly grow over the stent and cause a neointimal hyperplasia. In addition, if the stent damages the artery wall there is a strong
Coronary_stent
Surgical implant
October 1996). "Influence of external stent size on early medial and neointimal thickening in a pig model of saphenous vein bypass grafting". Circulation
External_support
Protein receptor active in neurons
Evans I, et al. (November 2015). "Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury". Cardiovascular
Neuropilin
Type of lipid raft in endocytosis
atherosclerosis: differential roles in fatty streak formation and neointimal hyperplasia". Current Opinion in Lipidology. 15 (5): 523–529. doi:10
Caveolae
Histone methylation on tail of histone H3 associated with gene bodies
novel regulator of vascular smooth muscle cells, controls vascular neointimal hyperplasia in diabetic rats". Atherosclerosis. 257: 152–163. doi:10.1016/j
H3K9me2
potassium channels. Patented by Merck, it can potentially prevent neointimal hyperplasia, a common cause of bypass graft failure. In addition to medical
Arachnids_in_medicine
Protein-coding gene in the species Homo sapiens
enhanced blood vessel neointimal thickening when challenged with vascular injury, indicating that NOV inhibits neoinitimal hyperplasia. Although NOV inhibits
CCN_family_member_3
Blockage of a grafted vein
K; Brian, L; Chien, L; Freedman, NJ (December 2004). "Vein graft neointimal hyperplasia is exacerbated by tumor necrosis factor receptor-1 signaling in
Vein_graft_failure
Protein family
Especially the cells in the cortical region had decreased in number Neointimal Hyperplasia is the movement and proliferation of smooth muscle cells into the
Margatoxin
to experiment with) a number of chemical agents to prevent the neointimal hyperplasia that is the cause of in-stent restenosis.[medical citation needed]
History of invasive and interventional cardiology
History_of_invasive_and_interventional_cardiology
Protein-coding gene in the species Homo sapiens
muscle cells in the context of pulmonary arterial hypertension and neointimal hyperplasia. Activation of ALDH1a3 in these cells causes vascular wall thickening
ALDH1A3
American physician
JA, Hunter WL, Froehlich JP. Paclitaxel stent coating inhibits neointimal hyperplasia at 4 weeks in a porcine model of coronary restenosis. Circulation
Benjamin_Abella
to be as effective as a paclitaxel-eluting stent in controlling Neointimal Hyperplasia. Bylander, Jessica (27 October 2008). "New Stents On The Block:
Genous
Genous stent promotes coronary vascular repair response and reduces neointimal hyperplasia after stent implantation. Although the Genous stent promotes rapid
Dual_therapy_stent
MicroRNA
miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia". Circ Res. 104 (4): 476–487. doi:10.1161/CIRCRESAHA.108.185363
Mir-221_microRNA
American cardiologist
C; Hruban, RH; et al. (2001). "Paclitaxel stent coating inhibits neointimal hyperplasia at 4 weeks in a porcine model of coronary restenosis". Circulation
Alan_Heldman
Protein-coding gene in the species Homo sapiens
muscle cell injury phenotypes: a novel target for the prevention of neointimal hyperplasia". Atherosclerosis. 203 (2): 377–86. doi:10.1016/j.atherosclerosis
Tetraspanin_9
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