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Chemical compound
Odanacatib (INN; codenamed MK-0822) is an investigational treatment for osteoporosis and bone metastasis. It is an inhibitor of cathepsin K, an enzyme
Odanacatib
Protein found in humans
inhibitor, odanacatib, in Phase III clinical trials for osteoporosis. In September, 2016, Merck announced they were discontinuing development of odanacatib after
Cathepsin_K
Protein family of cysteine protease enzymes
of mouse cathepsin K structural elements that regulate the potency of odanacatib". The Biochemical Journal. 474 (5): 851–864. doi:10.1042/BCJ20160985.
Papain-like_protease
Ocuclear Ocufen Ocuflox Ocumycin Ocupress Ocusert Pilo Ocusulf Oczyesa odanacatib (USAN) odronextamab (INN) odulimomab (INN) ofatumumab (INN) ofloxacin
List_of_drugs:_O–Op
Family of proteases
and chronic pain. Cathepsin K inhibitors, Relacatib, Balicatib, and Odanacatib, were terminated during clinical trials at phases I, II, and III, respectively
Cathepsin
Enzyme attached to an inert material
actually used in other pharmaceutical applications for the production of Odanacatib, and Sofosbuvir. Zaushitsyna O, Berillo D, Kirsebom H, Mattiasson B (2013)
Immobilized_enzyme
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