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Search references for OLIG2. Phrases containing OLIG2
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Protein found in humans
Oligodendrocyte transcription factor (OLIG2) is a basic helix-loop-helix (bHLH) transcription factor encoded by the OLIG2 gene. The protein is of 329 amino
OLIG2
Aggressive type of brain cancer
biomarkers is unreliable. IDH-wildtype glioblastomas usually have lower OLIG2 expression compared with IDH-mutant lower grade astrocytomas. In patients
Glioblastoma
Nerve cell sending impulse to muscle
Transcription factors here include Pax6, OLIG2, Nkx-6.1, and Nkx-6.2, which are regulated by sonic hedgehog (Shh). The OLIG2 gene being the most important due
Motor_neuron
Central organ of the human nervous system
GFAP and S100B whereas myelin basic protein and the transcription factor OLIG2 are expressed in oligodendrocytes. Cerebrospinal fluid is a clear, colourless
Human_brain
Neural cell type
are typically identified by their expression of the transcription factor OLIG2. Most oligodendrocytes develop during embryogenesis and early postnatal
Oligodendrocyte
Protein structural motif
NEUROG2; NEUROG3; NHLH1; NHLH2; NPAS1; NPAS2; NPAS3; NPAS4; OAF1; OLIG1; OLIG2; OLIG3; PTF1A; SCL; SCXB; SIM1; SIM2; SOHLH1; SOHLH2; SREBF1; SREBF2; TAL1;
Basic_helix–loop–helix
Developmental precursor to the central nervous system
Retinoic acid is required ventrally along with Shh to induce Pax6 and Olig2 during differentiation of motor neurons. Three main ventral cell types are
Neural_tube
Neuroscientist and pediatrician
and multiple sclerosis. His laboratory was the first to isolate Olig1 and Olig2, two related bHLH transcription factors which are essential for the differentiation
David_Rowitch
South Korean neuroscientist and neuroimmunologist
co-first author highlighted the finding that the transcription factor, Olig2, sequentially defines motor neuron and oligodendrocyte fate specification
Gloria_Choi
Medical condition
differentiation obsolete in the future. Although, in normal brain tissue, OLIG2 expresses on oligodendrocytes but not on mature astrocytes, it expresses
Oligodendroglioma
Subtype of glial cell in the central nervous system
of Olig1 and Olig2 in neuroepithelial cells of the pMN and p3 domains of the ventral ventricular zone. Together, Nkx2.2 and Olig1/Olig2 drive OPC specification
Oligodendrocyte progenitor cell
Oligodendrocyte_progenitor_cell
Critical protein in embryonic development
expresses a highly individualized combination of transcription factors—Nkx2.2, Olig2, Nkx6.1, Nkx6.2, Dbx1, Dbx2, Irx3, Pax6, and Pax7—that is regulated by the
Sonic_hedgehog_protein
Hospital and academic medical center in New York City
Adolfo García-Sastre, Peter Palese and colleagues for modern research. OLIG2 gene linked to schizophrenia is discovered. Proteins associated with ALS
Mount Sinai Hospital (Manhattan)
Mount_Sinai_Hospital_(Manhattan)
Protein-coding gene in the species Homo sapiens
humans is encoded by the OLIG1 gene. Oligodendrocyte Transcription factor OLIG2 GRCh38: Ensembl release 89: ENSG00000184221 – Ensembl, May 2017 GRCm38:
OLIG1
Use of stem cells to treat or prevent a disease or condition
remyelination detected by Myelin Basic Proteins, positive differentiation into Olig2 positive oligodendrocytes, prevented the glial scar formation and restored
Stem-cell_therapy
Human chromosome
receptor-interacting protein 1 OLIG1: encoding oligodendrocyte transcription factor 1 OLIG2: encoding oligodendrocyte transcription factor 2 PAXBP1: encoding protein
Chromosome_21
Natural partial recreation of myelin sheaths in the brain
dysregulation. Possible genes involved inside this pathway are TCF4 and OLIG2 which are both expressed in high amounts in areas where remyelination has
Remyelination
ENSG00000184221 bHLH Known motif – High-throughput in vitro [658] AVCATATGKT OLIG2 ENSG00000205927 bHLH Known motif – High-throughput in vitro [659] AMCATATGKY
List of human transcription factors
List_of_human_transcription_factors
Protein-coding gene in the species Homo sapiens
Rowitch DH, Stiles CD (Oct 2003). "Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with
NKX2-2
of scute (lsc) vertebrates E-12 Math1, Math5 Nato3 Beta3, Beta4, Olig1, Olig2, Olig3 NeuroD1 (NeuroD), NeuroD2 (Ndrf), NeuroD4 (Math3), NeuroD6 (Math2
Proneural_genes
Protein family
reduced by inhibiting Nkx2.2 and Olig2 in neural progenitors while allowing the expression of Ngn2. The ability of Olig2 to induce expression of Ngn2 is
Neurogenins
Transient structure in animal development
decrease in expression of Olig2, while when the Gli2 protein was mutated, the expression of Olig2 was not detected. Olig2 is normally expressed in the
Rhombomere
Protein-coding gene in the species Homo sapiens
Chemistry. 277 (30): 26761–8. doi:10.1074/jbc.M202078200. PMID 12004059. "OLIG2 oligodendrocyte lineage transcription factor 2 [Homo sapiens (human)] -
C8orf48
Protein-coding gene in the species Homo sapiens
PMC 528928. PMID 15489334. Lin YW, Deveney R, Barbara M, et al. (2005). "OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in
LMO1
Q68BL8 11046 OLFML3 HGNC:24956; Q9NRN5 11047 OLIG1 HGNC:16983; Q8TAK6 11048 OLIG2 HGNC:9398; Q13516 11049 OLIG3 HGNC:18003; Q7RTU3 11050 OLR1 HGNC:8133; P78380
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
Line of stem cells for research
causing a substantial increase in their numbers which express SOX6, SOX10 and OLIG2, markers of glial induction and OPC specification. As the myelin organoid
Myelinoid
OLIG2
OLIG2
OLIG2
OLIG2
Girl/Female
Indian, Sanskrit
Gold
Boy/Male
Arthurian Legend
Father of Guinevere.
Boy/Male
Biblical
An army; warring.
Girl/Female
Latin
Envious.
Boy/Male
Australian, Czech, Dutch, Hebrew
Laughter
Boy/Male
Irish
Hugh is a translation of an ancient name Aodh meaning “â€fire.â€â€ A name with nationalistic connotations as Hugh O’Neill, Earl of Tyrone and Red Hugh O’Donnell, Earl of Tyrconnell together led a rebellion and won some major battles against the forces of the English queen Elizabeth 1st, before being defeated at the Battle of Kinsale in 1601.
Surname or Lastname
English (Devon)
English (Devon) : habitational name from Eveleigh in Broad Clyst, Devon.
Boy/Male
American, British, English
From the Cross Meadow
Boy/Male
Muslim
Servant of the praiseworthy, The ever praised
Boy/Male
Tamil
One who is auspicious
OLIG2
OLIG2
OLIG2
OLIG2
OLIG2