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Protein
cyclin/CDK complexes, though is primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking
P21
Topics referred to by the same term
p21 is a cyclin-dependent kinase inhibitor. P21 or P-21 may also refer to: p21/ras, part of the RAt Sarcoma family of proteins Transforming protein p21
P21_(disambiguation)
p21 activated kinases (PAKs) are members of a family of enzymes. They serve as targets for the small GTP binding proteins CDC42 and Rac and have been
P21-activated_kinases
The P21 class is a class of inshore patrol vessels of the Armed Forces of Malta's Maritime Squadron. They are alternatively known as the Austal class
P21-class_patrol_vessel
GTP-binding proteins functioning on cell-cycle regulation
Ras, from "Rat sarcoma virus", is a family of related proteins that are expressed in all animal cell lineages and organs. All Ras protein family members
Ras_GTPase
The Phage 21 S (P21 Holin) Family (TC# 1.E.1) is a member of the Holin Superfamily II. The Bacteriophage P21 Lysis protein S holin (TC# 1.E.1.1.1) is the
P21_holin_family
Skills identified as being required for success in the 21st century
(SCANS), a national coalition called the Partnership for 21st Century Skills (P21), the international Organisation for Economic Co-operation and Development
21st_century_skills
Reciprocating internal combustion engine
The Glickenhaus by Pipo Moteurs P21 engine is a twin-turbocharged, four-stroke, 3.5-liter, V8 racing engine, designed and produced by Pipo Moteurs for
Glickenhaus by Pipo Moteurs P21 engine
Glickenhaus_by_Pipo_Moteurs_P21_engine
Protein-coding gene in the species Homo sapiens
RAS p21 protein activator 2 is a protein that in humans is encoded by the RASA2 gene. The protein encoded by this gene is member of the GAP1 family of
RAS_p21_protein_activator_2
French-Cypriot pianist (born 1951)
Nos. 31 & 12 P21 015 : A Tribute to Cyprus P21 016-A : Schumann • Vol. 1 • Live Recordings P21 017-N : Bach • Vol. 2 • Transcriptions P21 018 : Mozart
Cyprien_Katsaris
Ship built in 1977
LÉ Emer (P21) of the Irish Naval Service, now known as NNS Prosperity of the Nigerian Navy, was built as a patrol vessel in Verolme Dockyard, Cork, Ireland
LÉ_Emer
{\displaystyle (2_{0}2_{0}2_{0}2_{0})} ( ∗ 0 ∗ 0 ) {\displaystyle ({*}_{0}{*}_{0})} 4 P21 P 1 21 1 P 1 1 21 Γ m C 2 2 {\displaystyle \Gamma _{m}C_{2}^{2}} 1a ( b :
List_of_space_groups
Mammalian protein found in Homo sapiens
reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activated kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve
PAK1
Protein-coding gene in the species Homo sapiens
RAS p21 protein activator 4B is a protein that in humans is encoded by the RASA4B gene. GRCh38: Ensembl release 89: ENSG00000170667 – Ensembl, May 2017
RASA4B
Diplomatic summit resulting in the Paris Agreement
The 2015 United Nations Climate Change Conference, COP 21 or CMP 11 was held in Paris, France, from 30 November to 12 December 2015. It was the 21st yearly
2015 United Nations Climate Change Conference
2015_United_Nations_Climate_Change_Conference
Submarine of the Royal Navy
24 August 1927 Decommissioned 5 July 1944 Identification Pennant number P21 Fate Scrapped 1945 General characteristics Class & type Odin-class submarine
HMS_Oberon_(P21)
Protein-coding gene in humans
the "Harvey Rat sarcoma viral oncogene homolog" and transforming protein p21, is an enzyme that is encoded by the HRAS gene in humans. The HRAS gene is
HRAS
Widely used CAD 3D data exchange file format
modeling language specified in ISO 10303-11. A STEP-File is also called p21-File and STEP Physical File. The file extensions .stp and .step indicate
ISO_10303-21
Cancer of plasma cells
years t(14;16) IgH and C-MAF 2–5% Median overall survival: 5 years t(6;14)(p21;q32) IgH and CCND3 2% Median overall survival: 7–10 years t(14;20)(q32;q12)
Multiple_myeloma
Prime Minister of India since 2014
Modi (right) at CoP21 Climate Conference, in Paris, announcing the founding of the International Solar Alliance (ISA). November 2015.
Narendra_Modi
Protein-coding gene in humans
commonly known as the p21-activated protein kinase exchange factor beta (beta-PIX or βPIX), because it was identified by binding to p21-activated kinase (PAK)
ARHGEF7
States of matter for water as a solid
leading candidates for the space group of ice XIX: P-4, Pca21, Pcc2, P21/a, and P21/c. They also measured dielectric spectra in situ and determined phase
Phases_of_ice
Chemical compound
crystal structure belongs to the monoclinic system and has the space group P21/n, yellow crystals. Potassium tetrachloroiodate(III) can be obtained by reacting
Potassium tetrachloroiodate(III)
Potassium_tetrachloroiodate(III)
Motorcycle model
Battery 12 volt, 8 Ah Head lamp 12V, H4-60/55W (halogen) Tail lamp 12V, P21/5W Turn signal lamp 12V, R10W X 4nos First Generation Royal Enfield Classic
Royal_Enfield_Classic
Protein-coding gene in humans
nucleus. The gene product of KRAS, the K-Ras protein, was first found as a p21 GTPase. Like other members of the ras subfamily of GTPases, the K-Ras protein
KRAS
Uranium oxyanion associated with a monovalent or divalent cation
Ca3UO6 VI P21 monoclinic Cs2UO4 VI I4/mmm tetragonal MgU3O10 VI hexagonal Sr3UO6 VI P21 monoclinic MgUO4 VI Imma orthorhombic Li2U3O10 VI α: P21/c β: P2
Uranate
Mineral variety of copper carbonate
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/a Identification Formula mass 221.1 g/mol Color Bright green, dark green
Malachite
Mammalian protein found in Homo sapiens
PAK3 (p21-activated kinase 2, beta-PAK) is one of three members of Group I PAK family of evolutionary conserved serine/threonine kinases. PAK3 is preferentially
PAK3
XML grammar for geographical features
xlink:type="Simple" xlink:href="#p21"/> </abc:Building> <abc:SurveyMonument gml:id="g234"> <abc:position> <gml:Point gml:id="p21"> <gml:posList>100,200</gml:posList>
Geography_Markup_Language
Rare silicate mineral
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/m Identification Color Violet, lilac, light brown Crystal habit Fibrous,
Charoite
Class of proteins
name Gene Chromosomal locus Replication protein A1 RPA1 Chr. 17 p13.3 Replication protein A2 RPA2 Chr. 1 p35.3 Replication protein A3 RPA3 Chr. 7 p21.3
Single-stranded binding protein
Single-stranded_binding_protein
Road in Penang, Malaysia
Penang State Route P21, Song Ban Kheng Road or Jalan Song Ban Kheng is one of the main roads in Bukit Mertajam, Penang. It runs east–west to connect with
Penang_State_Route_P21
Animal cell cycle checkpoint
phosphorylation, as shown in the figure. p27 and p21 are stoichiometric inhibitors of G1/S- and S-cyclin-Cdk complexes. While p21 levels increase during cell-cycle entry
Restriction_point
Egyptian-American medical researcher
of WAF1 while working with Bert Vogelstein at Johns Hopkins University. p21(WAF1) was the first mammalian cell cycle inhibitor to be discovered, and
Wafik_El-Deiry
Rabbit: Explorations in Warner Bros. Animation p21 Reading the Rabbit: Explorations in Warner Bros. Animation p21 Milligan, Mercedes (April 2, 2026). "Annecy
Looney Tunes and Merrie Melodies filmography (1970–present)
Looney_Tunes_and_Merrie_Melodies_filmography_(1970–present)
Zeolite mineral group
Crystal class Dipyramidal (mmm) H-M symbol: (2/m 2/m 2/m) Space group Immm P21/n (Ferrierite-Na) Identification Color white, colorless, pinkish, orange
Ferrierite
Magnitude 6.7 earthquake in the Philippines
Malapatan, 136 of them seriously. Damage to roads in Sarangani amounted to P21.9 million. The municipal hall of Glan and a school were rendered unsafe for
November 2023 Mindanao earthquake
November_2023_Mindanao_earthquake
One of the 7 crystal systems in crystallography
halotrichite P2, P21 C2 6–9 Domatic Cs (C1h) m *11 [ ] polar hilgardite Pm, Pc Cm, Cc 10–12 Prismatic C2h 2/m 2* [2,2+] centrosymmetric gypsum P2/m, P21/m C2/m
Monoclinic_crystal_system
Class of chemical compounds
monoclinic P21/n a=6.7527 b=7.5077 c=11.8867 β =99.935 Z=4 593.59 5.361 RbTe1·25Mo0·75O6 a=10.469 (Ag,Na)2Te4O15 x=0.4 2:2 monoclinic P21/c a = 6.333
Tellurite_tellurate
Road in Ukraine
P21 road is a regional road (P-Highway) in Zakarpattia Oblast and Ivano-Frankivsk, Ukraine. It runs north-south and connects cities of Dolyna and Khust
P21_road_(Ukraine)
Chemical compound containing oxalate and phosphate anions
density comment references Phoxite (NH4)2Mg2(C2O4)(PO3OH)2(H2O)4 monoclinic P21/c a=7.2962 b=13.5993 c=7.8334 β=108.271° Z=2 738.07 1.98 mineral biaxial(-)
Oxalate_phosphate
528 c=6.438 Z=4 piperazin-diium (C4N2H12)[FeIIFeIII(HPO3)2F3] monoclinic P21/n a = 12.935 b = 6.4476 c = 15.693 β = 105.630° Z = 4 1260.4 2.196 brown
Phosphite_fluoride
Class of chemical compounds
451.22 LiBF2C2O4·2H2O lithium difluoro(oxalato)borate dihydrate monoclinic P21/c a = 9.5580 b = 12.7162 c = 5.4387 Z = 4 634.63 NaBF2C2O4 sodium difluoro(oxalato)borate
Oxalate_fluoride
Chemical compound
Crystal structure Monoclinic (α-form) Triclinic, aP228 (γ-form) Space group P21/a, No. 14 (α-form) P1, No. 2 (γ-form) Point group 2/m (α-form) 1 (γ-form)
Lauric_acid
Daily bus routes serving the metropolitan area of Washington, D.C., United States
Carrollton Line on Route P20, and Hanover Parkway-New Carrollton Line on Route P21, are daily bus routes operated by the Washington Metropolitan Area Transit
Greenbelt_Lines
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/a Identification Mohs scale hardness 5.5–6.0 Streak black Specific gravity
Ilvaite
Chemical compound
standard conditions SbPO4 crystallises in a monoclinic form with space group P21/m. Antimony phosphate has been investigated for use in lithium ion and sodium
Antimony_orthophosphate
Chemical compound
the doubly hydrogen-bonded 8-membered rings. The crystal has space group P21/C. Longer O—O distances are observed in strong intramolecular hydrogen bonds
Carbonic_acid
Nesosilicate mineral
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/a Unit cell a = 4.763, b = 14.29 c = 4.618 [Å]; β = 100.25°; Z = 4 Identification
Euclase
Family of protein complexes
NCBI gene 64240 HGNC 13886 OMIM 605459 RefSeq NM_022436 UniProt Q9H222 Other data Locus Chr. 2 p21 Search for Structures Swiss-model Domains InterPro
Sterolin
Sulfosalt mineral
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/a Identification Color grey-black Cleavage {001} good; also possibly {010}
Jamesonite
French industrialist (1858–1940)
Histoire & collections: 25. 2003. Ward's Auto World. May 2002, Vol. 38 Issue 5, p21. 1/6p. "» Édouard Michelin". automotivehalloffame.org. Retrieved 23 June
Édouard Michelin (industrialist)
Édouard_Michelin_(industrialist)
Very rare organic mineral
Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/c, P21/n Unit cell a = 1625 pm, b = 463.8 pm, c = 1042 pm; β = 111°10'; Z = 2
Carpathite
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/a Unit cell a = 10.63, b = 12.06 c = 8.4 [Å]; β = 114.03°; Z = 4 Identification
Inyoite
Chemical compound
susceptibility (χ) −346.0·10−6 cm3/mol Structure Space group monoclinic, P21/a Lattice constant a = 1.8431(3) nm, b = 0.5119(1) nm, c = 1.2929(2) nm α = 90°
Hexabenzocoronene
Monoclinic/orthogonal 8 p211 9 p2111 10 c211 11 pm11 12 pb11 13 cm11 14 p2/m11 15 p21/m11 16 p2/b11 17 p21/b11 18 c2/m11 Orthorhombic 19 p222 20 p2122 21 p21212 22 c222 23
Layer_group
Phosphate mineral (Zn2Fe(PO4)2 . 4H2O)
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/c Identification Formula mass 448.40 g/mol Color Blue-green to colourless
Phosphophyllite
Eighteen-carbon straight-chain fatty acid
°C) Structure Crystal structure B-form = Monoclinic Space group B-form = P21/a Point group B-form = Cs 2h Lattice constant a = 5.591 Å, b = 7.404 Å, c = 49
Stearic_acid
Oxygen deprivation to a newborn infant
Classification D ICD-10: P21 ICD-9-CM: 768 MeSH: D001238 DiseasesDB: 1416 External resources eMedicine: ped/149
Perinatal_asphyxia
Control mechanism in the eukaryotic cell cycle
target genes, including p21, an inhibitor of the G1-to-S promoting complex cyclin E-CDK2. In addition, another mechanism by which p21 is activated is through
Cell_cycle_checkpoint
Ability of a solid material to exist in more than one form or crystal structure
is allowed to evaporate slowly. Whereas form I has monoclinic space group P21/c, the new form has space group Pc. Both polymorphs consist of sheets of
Crystal_polymorphism
Sulfite mineral
the indexed powder data. A subsequent study determined the space group is P21/m (no. 11) with unit cell dimensions: a = 4.505 Å, b = 5.333 Å, c = 6.405 Å;
Scotlandite
Class of chemical compounds
octahedra; melts incongruently at 268 °C K5Tl8 melts at 273 °C K10Tl7 monoclinic P21/c a = 10.132 b = 22.323 c = 13.376 β = 93.14° Z=4 [Tl7]7– pentagonal bipyramid
Thallide
Protein-coding gene in the species Homo sapiens
RAS p21 protein activator 1 or RasGAP (Ras GTPase activating protein), also known as RASA1, is a 120-kDa cytosolic human protein that provides two principal
RAS_p21_protein_activator_1
Central nervous system stimulant
and water. The crystal structure of either enantiomer is monoclinic with P21 space group; at 90 K (−183.2 °C; −297.7 °F), it has lattice parameters a
Methamphetamine
Protein-coding gene in the species Homo sapiens
This gene product was isolated based on its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple
BCCIP
Mineral
official mineral designation was also given. It is monoclinic, with space group P21/c (space group 14). Elkinstantonite was first identified in nature by scientists
Elkinstantonite
Member of the cyclin protein family
they are also promoters of the cyclin D-CDK4/6 complex. Without p27 and p21, cyclin D levels are reduced and the complex is not formed at detectable
Cyclin_D
Yellow-green phosphate mineral
system that is part of the point group 2/m and belongs to the space group P21/n. The crystals of brazilianite are elongated and prismatic along [100].
Brazilianite
Supermini car produced by Peugeot
Second generation Peugeot e-208 GT Overview Model code P21 Production 2019–present Assembly Slovakia: Trnava (Trnava Plant) Spain: Zaragoza (Opel España
Peugeot_208
American historian (1928–1996)
Nicholas Wahl; Obituary. The Times (London, England). (20 September 1996) News: p21. Word Count: 672 Outsider in France's inner circle: Obituary of Nicholas
Nicholas_Wahl
música en Cuba. La Habana. vol 4, p21. Spelt 'Creach' in Giro Radamés 2007. Diccionario enciclopédico de la música en Cuba. La Habana. vol 4, p21. v t e
Vieja_Trova_Santiaguera
Chemical compound
either side. It occurs in two crystalline forms, α and β. Both have the P21/c monoclinic symmetry and a density of ca. 1.7 g/cm3, which is relatively
Perylenetetracarboxylic dianhydride
Perylenetetracarboxylic_dianhydride
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/b Unit cell a = 9.68, b = 10.38 c = 9.38 [Å], β = 90.00° (approximated) Z = 4
Ichnusaite
Chemical compound
(anhydrous) C2/c, No. 15 (monohydrate, hexahydrate) P21/n, No. 14 (tetrahydrate) P1, No. 2 (pentahydrate) P21/c, No. 14 (heptahydrate) Point group 2/m 2/m 2/m
Iron(II)_sulfate
Australian defence company
Austal Limited is an Australian-based global ship building company and defence prime contractor that specialises in the design, construction and support
Austal
Arsenate mineral
the arthurite group members Arthurite is of the monoclinic space group: P21/c with a = 10.189(2)Å, b = 9.649(2)Å, c = 5.598(1)Å and β = 92.16(2). The
Arthurite
Class of chemical compounds
density properties references Boroseleniteselenate B2Se3O10 1:2 monoclinic P21/c a = 4.3466, b = 7.0237, c = 22.1460, β = 94.922°, Z = 4 colourless hygroscopic
Selenate_selenite
Chemical compound
Refractive index (nD) 1.644 Structure Crystal structure monoclinic Space group P21/c, No. 14 Lattice constant a = 15.5641(8) Å, b = 4.6564(3) Å, c = 21.1029(15)
N-Benzoyl-N'-phenylurea
Mammalian protein found in Homo sapiens
PAK1, PAK2 contains a p21-binding domain (PBD) and an auto-inhibitory domain (AID) and exists in an inactive conformation. The p21 activated kinases (PAK)
PAK2
Rare mercury(I) basic carbonate mineral
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/c Identification Color pale greenish yellow Crystal habit tabular, subhedral
Clearcreekite
Pennant number Builder Date of launch Notes Andromeda (gk) ("Andromeda") P21 Westermoen 1965 renumbered P196 in 1982, decommissioned 1983. re-engined
Greek_Tjeld-type_patrol_boat
Sulfate mineral
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/c Unit cell a = 20.870, b = 6.135 c = 22.91 [Å], β = 102.73° V = 2,861.23 Å3
Devilline
Mammalian protein found in humans
p21. Upon activation by p53, p21 inhibits cyclin-dependent kinases, leading to cell cycle arrest and contributing to tumor suppression. However, p21 can
P53
Fastening mechanism
Miniature bayonet cap (MBC) 1 9 mm BA15d Small bayonet cap (SBC) 2 15 mm BAY15d (P21/5W, 1157) 2 15 mm, axially offset pins BAX15s 1 15 mm, radially offset pins
Bayonet_mount
Chemical compound
−50 °C. The most common structure of WO3 is monoclinic with space group P21/n. The pure compound is an electric insulator, but oxygen-deficient varieties
Tungsten_trioxide
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/c Unit cell a = 9.909 Å, b = 9.655 Å, c = 8.502 Å; β = 97.20°; Z = 16 Identification
Pararealgar
British single-seat WWII fighter aircraft
Price 1982, p. 17. Price 1977, p. 20. Glancey 2006, pp. 37–38. Price 2002 p21 Price 2003, p. 21. Price 2002 p23 Morgan and Shacklady 2000, p. 27. Gunston
Supermarine_Spitfire
Class of chemical compounds
1:1 monoclinic P21/c a = 7.8520 b = 6.7922 c = 17.5394 β = 95.440° Z = 4 931.2 (Co(NH3)4CO3)(NO3)·(H2O)0.5 1:1 monoclinic P21/n a=7.4319 b=22.647
Carbonate_nitrate
Pharmaceutical compound
Padnarsertib (KPT-9274), is a drug which acts as a dual inhibitor of the enzymes p21-activated kinase 4 (PAK4) and nicotinamide phosphoribosyltransferase (NAMPT)
Padnarsertib
Pharmaceutical compound
PF-3758309 is an experimental anticancer drug which acts as an inhibitor of p21-activated kinases with highest affinity for PAK4. It shows activity against
PF-3758309
system Monoclinic Crystal class Prismatic (2/m) (same H-M symbol) Space group P21/b Identification Color Colourless, white, pale lilac; brownish or reddish
Thomsenolite
Chemical compound
(N2H6)(H2PO2)2 monoclinic P21/c a = 7.74 b = 6.44 c = 6.77 β = 98.1° 1,3-diaminoguanidinium(1+) hypophosphite (CN5H8)H2PO2 monoclinic P21/c ?P21/m a=6.3673 b=14
Phosphinate
Class of inorganic chemical compounds
BeP2N4 cubic Fd3 a=7.1948 Z=8 372.44 bulk modulus 325 GPa BP3N6 monoclinic P21/c a=5.027 b=4.5306 c=17.332 β=106.387° Z=4 378.7 3.293 Li47B3P14N42 trigonal
Nitridophosphate
Class of enzymes
HGNC 2716 OMIM 604744 RefSeq NM_013974 UniProt O95865 Other data EC number 3.5.3.18 Locus Chr. 6 p21 Search for Structures Swiss-model Domains InterPro
Dimethylargininase
Enzyme
OMIM 169740 RefSeq NM_001166424 UniProt P20142 Other data EC number 3.4.23.3 Locus Chr. 6 pter-p21.1 Search for Structures Swiss-model Domains InterPro
Pepsin
NCBI gene 3108 HGNC 4934 OMIM 142855 RefSeq NM_006120 UniProt P28067 Other data Locus Chr. 6 p21.3 Search for Structures Swiss-model Domains InterPro
HLA-DM
Phosphate mineral
Exploration Company. Sampleite is monoclinic. It belongs to the space group P21/n or P21/c. In a thin section it has a high surface relief and will have sharp
Sampleite
Protein family
HGNC 7141 OMIM 158270 PDB 1lbj RefSeq NM_001040109 UniProt P12872 Other data Locus Chr. 6 p21.3-p21.2 Search for Structures Swiss-model Domains InterPro
Motilin
Carboxylic acid with chemical formula CH3CH2CO2H
495 cP (90 °C) Structure Crystal structure Monoclinic (−95 °C) Space group P21/c Lattice constant a = 4.04 Å, b = 9.06 Å, c = 11 Å α = 90°, β = 91.25°,
Propionic_acid
P21
P21
P21
P21
Boy/Male
American, Australian, British, English, Irish
King's Doorkeeper; Stranger; Variant of Dorran Stranger
Boy/Male
Tamil
Respected
Boy/Male
Indian
Merciful, Gentle
Boy/Male
English American Shakespearean
From the farm near the moor.
Surname or Lastname
English
English : occupational name for an innkeeper, Anglo-Norman French taverner (Old French tavernier, Late Latin tabernarius from taberna ‘shop’, ‘inn’).
Girl/Female
Indian, Sanskrit
Gladness; Happiness
Boy/Male
Hindu
Lord of the lamp, Name of poet
Boy/Male
Japanese
Praise; admirable.
Boy/Male
Indian
One who knows dates, Tall
Boy/Male
Indian
Capacious, Wide, Ample, One, Broad-minded, Liberal, Learn, All embracing
P21
P21
P21
P21
P21